IL158488A0 - Tir3 a novel taste receptor - Google Patents

Tir3 a novel taste receptor

Info

Publication number
IL158488A0
IL158488A0 IL15848802A IL15848802A IL158488A0 IL 158488 A0 IL158488 A0 IL 158488A0 IL 15848802 A IL15848802 A IL 15848802A IL 15848802 A IL15848802 A IL 15848802A IL 158488 A0 IL158488 A0 IL 158488A0
Authority
IL
Israel
Prior art keywords
tir3
taste receptor
novel taste
novel
receptor
Prior art date
Application number
IL15848802A
Other languages
English (en)
Original Assignee
Sinai School Medicine
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sinai School Medicine filed Critical Sinai School Medicine
Publication of IL158488A0 publication Critical patent/IL158488A0/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/72Receptors; Cell surface antigens; Cell surface determinants for hormones
    • C07K14/723G protein coupled receptor, e.g. TSHR-thyrotropin-receptor, LH/hCG receptor, FSH receptor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Endocrinology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
IL15848802A 2001-04-20 2002-04-22 Tir3 a novel taste receptor IL158488A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US28520901P 2001-04-20 2001-04-20
PCT/US2002/012656 WO2002086079A2 (en) 2001-04-20 2002-04-22 T1r3 a novel taste receptor

Publications (1)

Publication Number Publication Date
IL158488A0 true IL158488A0 (en) 2004-05-12

Family

ID=23093241

Family Applications (1)

Application Number Title Priority Date Filing Date
IL15848802A IL158488A0 (en) 2001-04-20 2002-04-22 Tir3 a novel taste receptor

Country Status (8)

Country Link
US (2) US20040219632A1 (xx)
EP (1) EP1572871A4 (xx)
JP (2) JP2005501519A (xx)
AU (1) AU2002305218B2 (xx)
CA (1) CA2445197A1 (xx)
IL (1) IL158488A0 (xx)
MX (1) MXPA03009580A (xx)
WO (1) WO2002086079A2 (xx)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7402400B2 (en) 2001-07-03 2008-07-22 Regents Of The University Of California Mammalian sweet taste receptors
US7803982B2 (en) 2001-04-20 2010-09-28 The Mount Sinai School Of Medicine Of New York University T1R3 transgenic animals, cells and related methods
CA2452716C (en) * 2001-07-03 2012-06-26 The Regents Of The University Of California Mammalian sweet and amino acid heterodimeric taste receptors
ES2259418T3 (es) 2002-07-22 2006-10-01 Ardana Bioscience Limited Metodo de deteccion sistematica y farmaco candidato antitumor.
US20050106571A1 (en) 2003-10-02 2005-05-19 The Regents Of The University Of California Mammalian T1R3 sweet taste receptors
WO2006113422A2 (en) * 2005-04-13 2006-10-26 The Government Of The Usa As Represented By The Secretary Of The Dept. Of Health And Human Services Human sweet and umami taste receptor variants
DE102005028453A1 (de) * 2005-06-17 2006-12-28 Philipps-Universität Marburg Verfahren zur Bestimmung und Beeinflussung der Fertilität männlicher Säugetiere und des Menschen
US20110097741A1 (en) * 2006-04-20 2011-04-28 Jay Patrick Slack Partial t1r2 nucleic acid sequence, receptor protein and its use in screening assays
TW200813232A (en) * 2006-06-08 2008-03-16 Senomyx Inc Rationale, methods, and assays for identifying novel taste cell genes and salty taste receptor targets and assays using these identified genes or gene products
JP5627479B2 (ja) * 2011-01-24 2014-11-19 日清食品ホールディングス株式会社 Skn−1a/iノックアウトマウスを用いた味蕾細胞マーカー分子の探索方法
US9128079B2 (en) 2011-08-08 2015-09-08 The Coca-Cola Company Methods of using lung or bronchial epithelial cells to identify bitter taste modulators
US20150045610A1 (en) * 2012-04-12 2015-02-12 Monell Chemical Senses Center Method of modifying spermatogenesis, spermiogenesis and/or fertility in mammals

Family Cites Families (81)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3725453A (en) * 1970-10-16 1973-04-03 American Home Prod L-4{40 -cyano-3-(2,2,2-trihaloacetamido) succinanilic acids
JPS5825980B2 (ja) * 1976-02-12 1983-05-31 ヤマサ醤油株式会社 サイクリックヌクレオチドの定量法
US4376110A (en) * 1980-08-04 1983-03-08 Hybritech, Incorporated Immunometric assays using monoclonal antibodies
US4873191A (en) * 1981-06-12 1989-10-10 Ohio University Genetic transformation of zygotes
ES507187A0 (es) * 1981-11-16 1983-01-01 Union Ind Y Agro Ganader S A U Procedimiento de obtencion de una leche humanizada adiciona-da de nucleotidos con destino a la alimentacion infantil.
US5168062A (en) * 1985-01-30 1992-12-01 University Of Iowa Research Foundation Transfer vectors and microorganisms containing human cytomegalovirus immediate-early promoter-regulatory DNA sequence
US5506337A (en) * 1985-03-15 1996-04-09 Antivirals Inc. Morpholino-subunit combinatorial library and method
US5034506A (en) * 1985-03-15 1991-07-23 Anti-Gene Development Group Uncharged morpholino-based polymers having achiral intersubunit linkages
US4921939A (en) * 1985-03-19 1990-05-01 Universite Claude Bernard -Lyon 1 Sweetening agents
US4826824A (en) * 1985-10-25 1989-05-02 Duke University Method of enhancing the taste perception of sweetness of aspartame and derivatives thereof
US4946778A (en) * 1987-09-21 1990-08-07 Genex Corporation Single polypeptide chain binding molecules
ES2007350A6 (es) * 1987-05-29 1989-06-16 Ganadera Union Ind Agro Productos alimenticios enriquecidos con nucleosidos yno nucleotidos para la nutricion infantil y de adultos, y procedimiento para su preparacion.
US4886646A (en) * 1988-03-23 1989-12-12 The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration Hanging drop crystal growth apparatus and method
US5010175A (en) * 1988-05-02 1991-04-23 The Regents Of The University Of California General method for producing and selecting peptides with specific properties
US5013716A (en) * 1988-10-28 1991-05-07 Warner-Lambert Company Unpleasant taste masking compositions and methods for preparing same
US5530101A (en) * 1988-12-28 1996-06-25 Protein Design Labs, Inc. Humanized immunoglobulins
US5096676A (en) * 1989-01-27 1992-03-17 Mcpherson Alexander Crystal growing apparatus
US5464764A (en) * 1989-08-22 1995-11-07 University Of Utah Research Foundation Positive-negative selection methods and vectors
US5792844A (en) * 1990-07-27 1998-08-11 Isis Pharmaceuticals, Inc. Oligonucleoside linkages containing adjacent nitrogen atoms
US5783682A (en) * 1990-07-27 1998-07-21 Isis Pharmaceuticals, Inc. Oligonucleotide mimics having nitrogen-containing linkages
US5217889A (en) * 1990-10-19 1993-06-08 Roninson Igor B Methods and applications for efficient genetic suppressor elements
US5130105A (en) * 1990-10-23 1992-07-14 The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration Protein crystal growth tray assembly
ATE250629T1 (de) * 1991-04-19 2003-10-15 Univ Washington Für säugetierphosphodiesterasen kodierende dns
US5221410A (en) * 1991-10-09 1993-06-22 Schering Corporation Crystal forming device
US5688662A (en) * 1992-04-09 1997-11-18 Linguagen Corporation Gustducin polynucleotides, vectors, host cells and recombinant methods
US5817759A (en) * 1992-04-09 1998-10-06 Linguagen Corporation Gustducin polypeptides and fragments
US6008000A (en) * 1992-04-09 1999-12-28 Linguagen Corporation Gustducin materials and methods
US5288514A (en) * 1992-09-14 1994-02-22 The Regents Of The University Of California Solid phase and combinatorial synthesis of benzodiazepine compounds on a solid support
US5884230A (en) * 1993-04-28 1999-03-16 Immunex Corporation Method and system for protein modeling
US5400741A (en) * 1993-05-21 1995-03-28 Medical Foundation Of Buffalo, Inc. Device for growing crystals
PT652960E (pt) * 1993-05-27 2001-08-30 Icos Corp Materiais para fosfodiesterases especificas e de ligacao do mpg ciclico e respectivos metodos
US5519134A (en) * 1994-01-11 1996-05-21 Isis Pharmaceuticals, Inc. Pyrrolidine-containing monomers and oligomers
US5389537A (en) * 1994-01-21 1995-02-14 Wisconsin Alumni Research Foundation Nuclease having altered specificity
US5593853A (en) * 1994-02-09 1997-01-14 Martek Corporation Generation and screening of synthetic drug libraries
US5539083A (en) * 1994-02-23 1996-07-23 Isis Pharmaceuticals, Inc. Peptide nucleic acid combinatorial libraries and improved methods of synthesis
US5637684A (en) * 1994-02-23 1997-06-10 Isis Pharmaceuticals, Inc. Phosphoramidate and phosphorothioamidate oligomeric compounds
US5525735A (en) * 1994-06-22 1996-06-11 Affymax Technologies Nv Methods for synthesizing diverse collections of pyrrolidine compounds
US5549974A (en) * 1994-06-23 1996-08-27 Affymax Technologies Nv Methods for the solid phase synthesis of thiazolidinones, metathiazanones, and derivatives thereof
US5569588A (en) * 1995-08-09 1996-10-29 The Regents Of The University Of California Methods for drug screening
WO1997014709A1 (en) * 1995-10-13 1997-04-24 F. Hoffmann-La Roche Ag Antisense oligomers
US5777195A (en) * 1996-05-17 1998-07-07 The Rockefeller University Knockout mutant mouse for DARPP-32 and use thereof
IL118460A (en) * 1996-05-28 1999-09-22 Dead Sea Works Ltd Edible salt mixture
US6004808A (en) * 1996-06-21 1999-12-21 Aurora Biosciences Corporation Promiscuous G-protein compositions and their use
US5814500A (en) * 1996-10-31 1998-09-29 The Johns Hopkins University School Of Medicine Delivery construct for antisense nucleic acids and methods of use
UA65549C2 (uk) * 1996-11-05 2004-04-15 Елі Ліллі Енд Компані Спосіб регулювання ожиріння шляхом периферійного введення аналогів та похідних glp-1 (варіанти) та фармацевтична композиція
PL342297A1 (en) * 1998-02-06 2001-06-04 Ilexus Pty Ltd Three-dimensional structures and models of fc receptors and their application
ATE474852T1 (de) * 1998-07-28 2010-08-15 Univ California Nukleinsäuren, die für einen an ein g-protein gekoppelten, an der sensorischen transduktion beteiligten rezeptor kodieren
EP1100810A4 (en) * 1998-07-28 2002-09-18 Univ California NUCLEIC ACIDS ENCODING G PROTEIN ASSOCIATED RECEPTORS WHICH INTERVENE IN SENSORY TRANSDUCTION
US7402400B2 (en) * 2001-07-03 2008-07-22 Regents Of The University Of California Mammalian sweet taste receptors
KR20010085308A (ko) * 1998-07-28 2001-09-07 린다 에스. 스티븐슨 감각 정보전달에 관여하는 단백질 암호 핵산
WO2000018788A1 (en) * 1998-09-30 2000-04-06 The Regents Of The University Of California Nucleic acids encoding a g protein gamma subunit involved in sensory transduction
US6558910B2 (en) * 1999-09-10 2003-05-06 The Regents Of The University Of California SF, a novel family of taste receptors
US7314716B2 (en) * 1999-11-19 2008-01-01 Mount Sinai School Of Medicine Gustducin γ subunit materials and methods
WO2001064882A2 (en) * 2000-02-29 2001-09-07 Millennium Pharmaceuticals, Inc. 1983, 52881, 2398, 45449, 50289, and 52872, g protein-coupled receptors and uses therefor
TW201006846A (en) * 2000-03-07 2010-02-16 Senomyx Inc T1R taste receptor and genes encidung same
US6608176B2 (en) * 2000-03-31 2003-08-19 University Of Miami Taste receptor for umami (monosodium glutamate) taste
MXPA02009843A (es) * 2000-04-07 2004-09-06 Senomyx Inc Receptores t2r del sabor y genes que codifican para los mismos.
AU2001251259A1 (en) * 2000-04-07 2001-10-23 Senomyx, Inc. Novel signal transduction molecules
AU2001257282A1 (en) * 2000-04-25 2001-11-07 The General Hospital Corporation Association of protein kinase c zeta polymorphisms with diabetes
WO2001083749A2 (en) * 2000-04-28 2001-11-08 Warner-Lambert Company Gene and sequence variation associated with sensing carbohydrate compounds and other sweeteners
EP1301595A2 (en) * 2000-05-22 2003-04-16 Incyte Genomics, Inc. G-protein coupled receptors
US7374878B2 (en) * 2000-06-22 2008-05-20 Senomyx, Inc. Receptor fingerprinting, sensory perception, and biosensors of chemical sensants
US7179614B2 (en) * 2000-09-14 2007-02-20 Mount Sinai School Of Medicine Screening methods to identify compounds that modulate type I phosphodiesterase (PDE) activity
US20030216545A1 (en) * 2000-09-28 2003-11-20 Spytek Kimberly A. Novel proteins and nucleic acids encoding same
GB0025572D0 (en) * 2000-10-18 2000-12-06 Glaxo Group Ltd New polypeptide
US7041457B2 (en) * 2000-10-30 2006-05-09 Senomyx, Inc. Gαq protein variants and their use in the analysis and discovery of agonists and antagonists of chemosensory receptors
WO2002036622A2 (en) * 2000-10-30 2002-05-10 Senomyx, Inc. GαqPROETIN VARIANTS AND THEIR USE IN THE ANALYSIS AND DISCOVERY OF AGONISTS AND ANTAGONISTS OF CHEMOSENSORY RECEPTORS
US20020164645A1 (en) * 2000-12-29 2002-11-07 The Regents Of The University Of California Assays for taste receptor cell specific ion channel
TW201022287A (en) * 2001-01-03 2010-06-16 Senomyx Inc T1R taste receptors and genes encoding same
AU2002251729A1 (en) * 2001-01-03 2002-08-28 Curagen Corporation G protein-coupled receptor-like proteins and nucleics acids encoding same
WO2002068593A2 (en) * 2001-02-23 2002-09-06 The Trustees Of Columbia University In The City Of New York Chemosensory gene family encoding gustatory and olfactory receptors and uses thereof
US7368285B2 (en) * 2001-03-07 2008-05-06 Senomyx, Inc. Heteromeric umami T1R1/T1R3 taste receptors and isolated cells that express same
US6955887B2 (en) * 2001-03-30 2005-10-18 Senomyx, Inc. Use of T1R hetero-oligomeric taste receptor to screen for compounds that modulate taste signaling
US7803982B2 (en) * 2001-04-20 2010-09-28 The Mount Sinai School Of Medicine Of New York University T1R3 transgenic animals, cells and related methods
US20040023294A1 (en) * 2001-05-22 2004-02-05 Arizu Chandra S. G-protein coupled receptors
US6942874B2 (en) * 2001-05-25 2005-09-13 Linguagen Corp. Nucleotide compounds that block the bitter taste of oral compositions
CA2452716C (en) * 2001-07-03 2012-06-26 The Regents Of The University Of California Mammalian sweet and amino acid heterodimeric taste receptors
AU2002336571A1 (en) * 2001-09-18 2003-04-01 Irm, Llc Sweet taste receptors
US7208290B2 (en) * 2001-12-14 2007-04-24 Senomyx, Inc. Methods of co-expressing umami taste receptors and chimeric Gα15 variants
EP1474516B1 (en) * 2002-01-25 2013-03-27 The Regents of The University of California Methods of modulating cold sensory perception
US20040018976A1 (en) * 2002-05-14 2004-01-29 Feder John N. Polynucleotide encoding novel human G-protein coupled receptors, and splice variants thereof

Also Published As

Publication number Publication date
JP2005501519A (ja) 2005-01-20
AU2002305218B2 (en) 2007-10-18
WO2002086079A3 (en) 2007-04-12
JP2010115201A (ja) 2010-05-27
EP1572871A2 (en) 2005-09-14
MXPA03009580A (es) 2004-12-06
CA2445197A1 (en) 2002-10-31
US20040219632A1 (en) 2004-11-04
EP1572871A4 (en) 2007-11-14
WO2002086079A2 (en) 2002-10-31
US20090217391A1 (en) 2009-08-27

Similar Documents

Publication Publication Date Title
EP1404928A4 (en) CONSTRUCTION
GB0113542D0 (en) A mechanism
GB0420901D0 (en) A seat
IL158488A0 (en) Tir3 a novel taste receptor
AU148688S (en) A spoon
AU149656S (en) A cart-housing
AU301861S (en) A toaster/breadbox
GB2374219B (en) A receiver
GB0119032D0 (en) A toaster
GB2370985B (en) A seat
HK1033241A2 (en) A novel mouse-device
AU148725S (en) A spout
GB0125183D0 (en) Receptor
GB0114929D0 (en) Receptor
GB0111959D0 (en) Receptor
GB0110662D0 (en) Receptor
GB0117369D0 (en) A barbecue
AU151778S (en) A spoon
AU146528S (en) A bowl
AU148023S (en) A cup
AU149291S (en) A confection
AU148760S (en) A frypan
AU143799S (en) A hatbox
AU147171S (en) A flumegate
AU145394S (en) A cord-lock