IL157756A0 - Novel expression vectors - Google Patents
Novel expression vectorsInfo
- Publication number
- IL157756A0 IL157756A0 IL15775602A IL15775602A IL157756A0 IL 157756 A0 IL157756 A0 IL 157756A0 IL 15775602 A IL15775602 A IL 15775602A IL 15775602 A IL15775602 A IL 15775602A IL 157756 A0 IL157756 A0 IL 157756A0
- Authority
- IL
- Israel
- Prior art keywords
- vectors
- present
- expression vectors
- provides
- expression
- Prior art date
Links
- 239000013604 expression vector Substances 0.000 title abstract 3
- 239000013598 vector Substances 0.000 abstract 3
- 230000014509 gene expression Effects 0.000 abstract 2
- 239000002157 polynucleotide Substances 0.000 abstract 2
- 102000040430 polynucleotide Human genes 0.000 abstract 2
- 108091033319 polynucleotide Proteins 0.000 abstract 2
- 108090000623 proteins and genes Proteins 0.000 abstract 2
- 238000003556 assay Methods 0.000 abstract 1
- 238000007876 drug discovery Methods 0.000 abstract 1
- 238000007877 drug screening Methods 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 239000002773 nucleotide Substances 0.000 abstract 1
- 125000003729 nucleotide group Chemical group 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 230000001105 regulatory effect Effects 0.000 abstract 1
- 230000002123 temporal effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/67—General methods for enhancing the expression
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01H—NEW PLANTS OR NON-TRANSGENIC PROCESSES FOR OBTAINING THEM; PLANT REPRODUCTION BY TISSUE CULTURE TECHNIQUES
- A01H6/00—Angiosperms, i.e. flowering plants, characterised by their botanic taxonomy
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
- A01K67/027—New or modified breeds of vertebrates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- General Health & Medical Sciences (AREA)
- Plant Pathology (AREA)
- Environmental Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Botany (AREA)
- Developmental Biology & Embryology (AREA)
- Immunology (AREA)
- Physiology (AREA)
- Analytical Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Animal Husbandry (AREA)
- Biodiversity & Conservation Biology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Measurement And Recording Of Electrical Phenomena And Electrical Characteristics Of The Living Body (AREA)
- Compositions Of Oxide Ceramics (AREA)
- Image Generation (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US27477001P | 2001-03-09 | 2001-03-09 | |
PCT/AU2002/000351 WO2002072844A1 (fr) | 2001-03-09 | 2002-03-08 | Nouveaux vecteurs d'expression |
Publications (1)
Publication Number | Publication Date |
---|---|
IL157756A0 true IL157756A0 (en) | 2004-03-28 |
Family
ID=23049549
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL15775602A IL157756A0 (en) | 2001-03-09 | 2002-03-08 | Novel expression vectors |
IL157756A IL157756A (en) | 2001-03-09 | 2003-09-04 | Methods for assaying activity of trancriptional control elements |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL157756A IL157756A (en) | 2001-03-09 | 2003-09-04 | Methods for assaying activity of trancriptional control elements |
Country Status (13)
Country | Link |
---|---|
US (3) | US7157272B2 (fr) |
EP (1) | EP1373528B1 (fr) |
JP (2) | JP2004530425A (fr) |
KR (1) | KR100917939B1 (fr) |
CN (1) | CN100471956C (fr) |
AT (1) | ATE404679T1 (fr) |
AU (1) | AU2002242474B2 (fr) |
CA (1) | CA2440148C (fr) |
DE (2) | DE02708018T1 (fr) |
IL (2) | IL157756A0 (fr) |
NZ (1) | NZ528000A (fr) |
WO (1) | WO2002072844A1 (fr) |
ZA (1) | ZA200306885B (fr) |
Families Citing this family (41)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7598079B2 (en) | 1998-12-24 | 2009-10-06 | Novation Pharmaceuticals, Inc. | Assay for identifying compounds which affect stability of mRNA |
WO2002072844A1 (fr) * | 2001-03-09 | 2002-09-19 | Gene Stream Pty Ltd | Nouveaux vecteurs d'expression |
ATE464317T1 (de) | 2001-06-05 | 2010-04-15 | Curevac Gmbh | Stabilisierte mrna mit erhöhtem g/c-gehalt für die gentherapie |
DE60330489D1 (de) * | 2002-09-16 | 2010-01-21 | Promega Corp | Schnell abgebaute reporter-fusionsproteine |
DE102004042546A1 (de) * | 2004-09-02 | 2006-03-09 | Curevac Gmbh | Kombinationstherapie zur Immunstimulation |
AR053279A1 (es) * | 2005-05-19 | 2007-04-25 | Monsanto Technology Llc | Regulacion post-transcripcional de la expresion genica |
US20070212332A1 (en) * | 2005-08-11 | 2007-09-13 | Department Of Veterans Affairs | Methods for accelerating bone repair |
EP1760092A1 (fr) * | 2005-08-26 | 2007-03-07 | Applied Research Systems ARS Holding N.V. | Système pour le criblage des cellules à haute expression d'une protéine d'intérêt |
WO2007038757A2 (fr) * | 2005-09-28 | 2007-04-05 | Attagene Inc. | Procedes et compositions d'evaluation non invasive d'une expression genique |
DE102005046490A1 (de) * | 2005-09-28 | 2007-03-29 | Johannes-Gutenberg-Universität Mainz | Modifikationen von RNA, die zu einer erhöhten Transkriptstabilität und Translationseffizienz führen |
US20070245258A1 (en) * | 2006-04-13 | 2007-10-18 | Codman Neuro Sciences Sàrl | Graphical user interface of an external control device for controlling an implantable medical device while minimizing human error |
EP2121921A4 (fr) * | 2006-12-13 | 2010-08-04 | Idiverse Inc | Nouveaux gènes et molécules d'arn qui confèrent une tolérance à la contrainte |
WO2008076844A2 (fr) * | 2006-12-13 | 2008-06-26 | Unl Technology Development Corporation | Nouveaux gènes et molécules d'arn conférant une tolérance au stress |
AU2007335194B2 (en) | 2006-12-21 | 2014-01-23 | Gene Stream Pty Ltd | Bioluminescent assays utilising secreted luciferases |
US20100239502A1 (en) * | 2007-07-11 | 2010-09-23 | Koninklijke Philips Electronics N.V. | In vivo expression analysis using ultrasound-induced transfection of reporter constructs |
US20090111099A1 (en) * | 2007-10-27 | 2009-04-30 | Yongsheng Ma | Promoter Detection and Analysis |
US20110071047A1 (en) * | 2007-10-27 | 2011-03-24 | O.D. 260 Inc. | Promoter detection and analysis |
KR101204895B1 (ko) | 2010-01-27 | 2012-11-26 | 단국대학교 산학협력단 | Prc1 유전자 프로모터의 삭제변이 프로모터를 함유하는 암세포 특이적 발현벡터 |
EP3578205A1 (fr) | 2010-08-06 | 2019-12-11 | ModernaTX, Inc. | Compositions pharmaceutiques a base d'acides nucléiques modifiés et leur utilisation medicale |
CN104531812A (zh) | 2010-10-01 | 2015-04-22 | 现代治疗公司 | 设计核酸及其使用方法 |
WO2012071631A1 (fr) | 2010-12-03 | 2012-06-07 | Gene Stream Pty Ltd | Molécules électroluminescentes améliorées |
JP2014511687A (ja) | 2011-03-31 | 2014-05-19 | モデルナ セラピューティクス インコーポレイテッド | 工学操作された核酸の送達および製剤 |
US9464124B2 (en) | 2011-09-12 | 2016-10-11 | Moderna Therapeutics, Inc. | Engineered nucleic acids and methods of use thereof |
ES2911677T3 (es) | 2011-10-03 | 2022-05-20 | Modernatx Inc | Nucleósidos, nucleótidos y ácidos nucleicos modificados, y sus usos |
RS63244B1 (sr) | 2011-12-16 | 2022-06-30 | Modernatx Inc | Kompozicije modifikovane mrna |
US9572897B2 (en) | 2012-04-02 | 2017-02-21 | Modernatx, Inc. | Modified polynucleotides for the production of cytoplasmic and cytoskeletal proteins |
US20140010861A1 (en) | 2012-04-02 | 2014-01-09 | modeRNA Therapeutics | Modified polynucleotides for the production of proteins associated with human disease |
US9878056B2 (en) | 2012-04-02 | 2018-01-30 | Modernatx, Inc. | Modified polynucleotides for the production of cosmetic proteins and peptides |
US9283287B2 (en) | 2012-04-02 | 2016-03-15 | Moderna Therapeutics, Inc. | Modified polynucleotides for the production of nuclear proteins |
LT2922554T (lt) | 2012-11-26 | 2022-06-27 | Modernatx, Inc. | Terminaliai modifikuota rnr |
US8980864B2 (en) | 2013-03-15 | 2015-03-17 | Moderna Therapeutics, Inc. | Compositions and methods of altering cholesterol levels |
CN104099357B (zh) * | 2013-04-12 | 2016-09-21 | 中国科学院上海生命科学研究院 | 检测蛋白质稳定性的方法及其应用 |
US10023626B2 (en) | 2013-09-30 | 2018-07-17 | Modernatx, Inc. | Polynucleotides encoding immune modulating polypeptides |
KR20160067219A (ko) | 2013-10-03 | 2016-06-13 | 모더나 세라퓨틱스, 인코포레이티드 | 저밀도 지단백질 수용체를 암호화하는 폴리뉴클레오타이드 |
EP3452101A2 (fr) * | 2016-05-04 | 2019-03-13 | CureVac AG | Arn codant pour une protéine thérapeutique |
MX2018015540A (es) | 2016-06-20 | 2019-04-11 | Janssen Vaccines & Prevention Bv | Promotor bidireccional potente y equilibrado. |
EP3506916B1 (fr) | 2016-09-01 | 2021-04-07 | Chimera Bioengineering Inc. | Lymphocytes t car optimisés avec de l'or |
JP2021518747A (ja) * | 2018-02-13 | 2021-08-05 | キメラ・バイオエンジニアリング,インコーポレーテッド | Rna不安定化エレメントを使用した遺伝子発現の調整 |
KR102490457B1 (ko) * | 2019-11-26 | 2023-01-19 | 한국생명공학연구원 | 단백질 발현용 mRNA 구조체 및 이의 용도 |
WO2022204471A1 (fr) * | 2021-03-26 | 2022-09-29 | Ptc Therapeutics Inc. | Régulation de l'expression de transgènes au moyen d'un commutateur d'épissage inductible à petites molécules |
WO2022250430A1 (fr) * | 2021-05-25 | 2022-12-01 | 한국생명공학연구원 | Procédé de préparation d'arnm pour exprimer une protéine, et utilisation de l'arnm ainsi préparé |
Family Cites Families (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2163212C (fr) * | 1993-05-18 | 2004-07-13 | Ahmed Abdullah Azad | Composes therapeutiques |
US5464758A (en) * | 1993-06-14 | 1995-11-07 | Gossen; Manfred | Tight control of gene expression in eucaryotic cells by tetracycline-responsive promoters |
US5587300A (en) * | 1994-04-26 | 1996-12-24 | Wisconsin Ulumni Research Foundation | Method to increase regulatory molecule production |
US5650135A (en) * | 1994-07-01 | 1997-07-22 | The Board Of Trustees Of The Leland Stanford Junior University | Non-invasive localization of a light-emitting conjugate in a mammal |
US5625048A (en) * | 1994-11-10 | 1997-04-29 | The Regents Of The University Of California | Modified green fluorescent proteins |
US5777079A (en) * | 1994-11-10 | 1998-07-07 | The Regents Of The University Of California | Modified green fluorescent proteins |
US5804387A (en) * | 1996-02-01 | 1998-09-08 | The Board Of Trustees Of The Leland Stanford Junior University | FACS-optimized mutants of the green fluorescent protein (GFP) |
EP1484409B1 (fr) * | 1996-12-16 | 2009-04-08 | Eisai R&D Management Co., Ltd. | Construction d'AND comprenant un gène de résistance à un médicament et un gène étranger |
US6231880B1 (en) * | 1997-05-30 | 2001-05-15 | Susan P. Perrine | Compositions and administration of compositions for the treatment of blood disorders |
EP1021549A2 (fr) * | 1997-09-19 | 2000-07-26 | Sequitur, Inc. | THERAPIES GENIQUES A BASE D'ARNm SENS |
US6130313A (en) * | 1997-10-02 | 2000-10-10 | Clontech Laboratories, Inc. | Rapidly degrading GFP-fusion proteins |
US6306600B1 (en) * | 1998-04-17 | 2001-10-23 | Clontech Laboratories, Inc. | Rapidly degrading GFP-fusion proteins and methods of use |
US5965421A (en) * | 1997-11-26 | 1999-10-12 | Human Genome Sciences, Inc. | Human IRAK-2 |
JPH11266872A (ja) * | 1998-03-20 | 1999-10-05 | Suntory Ltd | NF−κBの活性化を抑制する物質のスクリーニング方法 |
US20040002056A1 (en) * | 1998-05-12 | 2004-01-01 | Lorens James B. | Methods of screening for bioactive agents using cells transformed with self-inactivating viral vectors |
US6307123B1 (en) * | 1998-05-18 | 2001-10-23 | Dekalb Genetics Corporation | Methods and compositions for transgene identification |
AU779438B2 (en) * | 1998-12-24 | 2005-01-27 | Novation Pharmaceuticals Inc. | Compounds which affect mRNA stability and uses therefor |
GB9828709D0 (en) * | 1998-12-24 | 1999-02-17 | Novartis Ag | Assay |
US20020102638A1 (en) * | 2000-01-31 | 2002-08-01 | Rosen Craig A. | Nucleic acids, proteins, and antibodies |
US6841362B1 (en) * | 2000-02-29 | 2005-01-11 | The Trustees Of Columbia University In The City Of New York | Melanoma differentiation associated gene-7 promoter and uses thereof |
AU2001257428A1 (en) * | 2000-04-28 | 2001-11-12 | Message Pharmaceuticals, Inc. | Methods for identifying novel nucleic acid regulatory elements and compounds that affect the regulation |
WO2002072844A1 (fr) * | 2001-03-09 | 2002-09-19 | Gene Stream Pty Ltd | Nouveaux vecteurs d'expression |
EP2718441A1 (fr) * | 2011-04-20 | 2014-04-16 | King Faisal Specialist Hospital And Research Centre | Système de fluorescence d'origine cellulaire à élément de réponse à de multiples interférons et virus |
US20180305776A1 (en) * | 2017-04-20 | 2018-10-25 | The Board Of Trustees Of The Leland Stanford Junior University | Myc-reporters, cells containing myc-reporters and methods of use thereof |
-
2002
- 2002-03-08 WO PCT/AU2002/000351 patent/WO2002072844A1/fr active IP Right Grant
- 2002-03-08 DE DE02708018T patent/DE02708018T1/de active Pending
- 2002-03-08 IL IL15775602A patent/IL157756A0/xx unknown
- 2002-03-08 KR KR1020037011649A patent/KR100917939B1/ko active IP Right Grant
- 2002-03-08 AT AT02708018T patent/ATE404679T1/de not_active IP Right Cessation
- 2002-03-08 AU AU2002242474A patent/AU2002242474B2/en not_active Ceased
- 2002-03-08 NZ NZ528000A patent/NZ528000A/en not_active IP Right Cessation
- 2002-03-08 DE DE60228212T patent/DE60228212D1/de not_active Expired - Lifetime
- 2002-03-08 JP JP2002571895A patent/JP2004530425A/ja not_active Withdrawn
- 2002-03-08 EP EP02708018A patent/EP1373528B1/fr not_active Expired - Lifetime
- 2002-03-08 CN CNB028082532A patent/CN100471956C/zh not_active Expired - Fee Related
- 2002-03-08 CA CA2440148A patent/CA2440148C/fr not_active Expired - Lifetime
-
2003
- 2003-09-03 ZA ZA200306885A patent/ZA200306885B/xx unknown
- 2003-09-04 IL IL157756A patent/IL157756A/en unknown
- 2003-09-09 US US10/658,093 patent/US7157272B2/en not_active Expired - Lifetime
-
2006
- 2006-10-04 US US11/542,982 patent/US9994858B2/en active Active
-
2010
- 2010-08-02 JP JP2010173310A patent/JP2011015685A/ja active Pending
-
2018
- 2018-04-25 US US15/962,062 patent/US20180305705A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
EP1373528B1 (fr) | 2008-08-13 |
AU2002242474B2 (en) | 2004-05-20 |
EP1373528A4 (fr) | 2004-12-29 |
US9994858B2 (en) | 2018-06-12 |
US20040209274A2 (en) | 2004-10-21 |
US20040115704A1 (en) | 2004-06-17 |
US20180305705A1 (en) | 2018-10-25 |
US20070298417A1 (en) | 2007-12-27 |
KR100917939B1 (ko) | 2009-09-21 |
DE02708018T1 (de) | 2004-09-30 |
JP2011015685A (ja) | 2011-01-27 |
CA2440148C (fr) | 2012-07-10 |
ZA200306885B (en) | 2009-03-25 |
WO2002072844A1 (fr) | 2002-09-19 |
IL157756A (en) | 2010-12-30 |
EP1373528A1 (fr) | 2004-01-02 |
KR20030092013A (ko) | 2003-12-03 |
JP2004530425A (ja) | 2004-10-07 |
CN100471956C (zh) | 2009-03-25 |
NZ528000A (en) | 2005-09-30 |
CN1503844A (zh) | 2004-06-09 |
CA2440148A1 (fr) | 2002-09-19 |
ATE404679T1 (de) | 2008-08-15 |
DE60228212D1 (de) | 2008-09-25 |
US7157272B2 (en) | 2007-01-02 |
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