IL151242A0 - A solution of human collagenase 3 and crystalline fragments thereof - Google Patents
A solution of human collagenase 3 and crystalline fragments thereofInfo
- Publication number
- IL151242A0 IL151242A0 IL15124201A IL15124201A IL151242A0 IL 151242 A0 IL151242 A0 IL 151242A0 IL 15124201 A IL15124201 A IL 15124201A IL 15124201 A IL15124201 A IL 15124201A IL 151242 A0 IL151242 A0 IL 151242A0
- Authority
- IL
- Israel
- Prior art keywords
- solution
- human collagenase
- crystalline fragments
- fragments
- crystalline
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N9/00—Investigating density or specific gravity of materials; Analysing materials by determining density or specific gravity
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
- C12N9/6489—Metalloendopeptidases (3.4.24)
- C12N9/6491—Matrix metalloproteases [MMP's], e.g. interstitial collagenase (3.4.24.7); Stromelysins (3.4.24.17; 3.2.1.22); Matrilysin (3.4.24.23)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
- C12Q1/37—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving peptidase or proteinase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
- C12Y304/24—Metalloendopeptidases (3.4.24)
- C12Y304/24017—Stromelysin 1 (3.4.24.17)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2299/00—Coordinates from 3D structures of peptides, e.g. proteins or enzymes
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Biotechnology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Biophysics (AREA)
- General Physics & Mathematics (AREA)
- Rheumatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Pathology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Enzymes And Modification Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/514,026 US6934639B1 (en) | 2000-02-25 | 2000-02-25 | Methods for designing agents that interact with MMP-13 |
| PCT/US2001/005150 WO2001063244A1 (en) | 2000-02-25 | 2001-02-16 | Solution and crystal structures of mmp-13 active site and uses thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL151242A0 true IL151242A0 (en) | 2003-04-10 |
Family
ID=24045514
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL15124201A IL151242A0 (en) | 2000-02-25 | 2001-02-16 | A solution of human collagenase 3 and crystalline fragments thereof |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US6934639B1 (pt) |
| EP (1) | EP1274980A4 (pt) |
| JP (1) | JP2003524176A (pt) |
| KR (1) | KR20020089362A (pt) |
| CN (1) | CN1423748A (pt) |
| AU (1) | AU2001241534A1 (pt) |
| BR (1) | BR0108684A (pt) |
| CA (1) | CA2401063A1 (pt) |
| EA (1) | EA200200904A1 (pt) |
| HK (1) | HK1052553A1 (pt) |
| HU (1) | HUP0301720A2 (pt) |
| IL (1) | IL151242A0 (pt) |
| NO (1) | NO20024044L (pt) |
| PL (1) | PL359819A1 (pt) |
| WO (1) | WO2001063244A1 (pt) |
| ZA (1) | ZA200206248B (pt) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MXPA01013171A (es) | 2001-02-14 | 2004-05-21 | Warner Lambert Co | Inhibidores triciclicos de sulfonamida de metaloproteinasa de matriz. |
| MXPA01013326A (es) | 2001-02-14 | 2002-08-26 | Warner Lambert Co | Bifenil sulfonamidas utiles como inhibisdores de metaloproteinasa de matriz. |
| DOP2002000333A (es) | 2001-02-14 | 2002-09-30 | Warner Lambert Co | Derivados de acido isoftalico como inhibidores de metaloproteinasas de la matriz |
| MXPA01013172A (es) | 2001-02-14 | 2002-08-21 | Warner Lambert Co | Inhibidores sulfonamida de metaloproteinasa de matriz. |
| ES2231708T3 (es) | 2001-02-14 | 2005-05-16 | Warner-Lambert Company Llc | Benzotiadicinas inhibidoras de metaloproteinasa de matriz. |
| DOP2002000332A (es) | 2001-02-14 | 2002-08-30 | Warner Lambert Co | Inhibidores de piridina de metaloproteinasas de la matriz |
| EP1368323B1 (en) | 2001-02-14 | 2010-06-30 | Warner-Lambert Company LLC | Pyrimidine matrix metalloproteinase inhibitors |
| PA8539501A1 (es) | 2001-02-14 | 2002-09-30 | Warner Lambert Co | Compuestos triazolo como inhibidores de mmp |
| US6924276B2 (en) | 2001-09-10 | 2005-08-02 | Warner-Lambert Company | Diacid-substituted heteroaryl derivatives as matrix metalloproteinase inhibitors |
| US6962922B2 (en) | 2001-10-12 | 2005-11-08 | Warner-Lambert Company Llc | Alkynylated quinazoline compounds |
| CA2462442A1 (en) | 2001-10-12 | 2003-04-24 | Warner-Lambert Company Llc | Alkyne matrix metalloproteinase inhibitors |
| US6894057B2 (en) | 2002-03-08 | 2005-05-17 | Warner-Lambert Company | Oxo-azabicyclic compounds |
| US6747147B2 (en) | 2002-03-08 | 2004-06-08 | Warner-Lambert Company | Oxo-azabicyclic compounds |
| AU2003250470A1 (en) | 2002-08-13 | 2004-02-25 | Warner-Lambert Company Llc | Pyrimidinone fused bicyclic metalloproteinase inhibitors |
| WO2004014378A1 (en) | 2002-08-13 | 2004-02-19 | Warner-Lambert Company Llc | 3-isoquinolinone derivatives as matrix metalloproteinase inhiitors |
| MXPA05001785A (es) | 2002-08-13 | 2005-04-25 | Warner Lambert Co | Derivados de cromona como inhibidores de las metaloproteinasas de matriz. |
| BR0313724A (pt) | 2002-08-13 | 2005-06-28 | Warner Lambert Co | Derivados de azaisoquinolina como inibidores de metaloproteinase de matriz |
| WO2004014375A2 (en) | 2002-08-13 | 2004-02-19 | Warner-Lambert Company Llc | Fused bicyclic metalloproteinase inhibitors |
| AU2003249477A1 (en) | 2002-08-13 | 2004-02-25 | Warner-Lambert Company Llc | Heterobicylcic metalloproteinase inhibitors |
| EP1553949B1 (en) | 2002-08-13 | 2007-04-18 | Warner-Lambert Company LLC | Pyrimidine-2,4-dione derivatives as matrix metalloproteinase inhibitors |
| AU2003253186A1 (en) | 2002-08-13 | 2004-02-25 | Warner-Lambert Company Llc | Fused tetrahydropyridine derivatives as matrix metalloproteinase inhibitors |
| WO2004014892A1 (en) | 2002-08-13 | 2004-02-19 | Warner-Lambert Company Llc | Monocyclic derivatives as matrix metalloproteinase inhibitors |
| PA8578101A1 (es) | 2002-08-13 | 2004-05-07 | Warner Lambert Co | Derivados de heterobiarilo como inhibidores de metaloproteinasa de la matriz |
| US7189700B2 (en) * | 2003-06-20 | 2007-03-13 | Kimberly-Clark Worldwide, Inc. | Anti-chrondrosarcoma compounds |
| US11094399B2 (en) * | 2011-01-11 | 2021-08-17 | Shimadzu Corporation | Method, system and program for analyzing mass spectrometoric data |
| GB201505305D0 (en) | 2015-03-27 | 2015-05-13 | Immatics Biotechnologies Gmbh | Novel Peptides and combination of peptides for use in immunotherapy against various tumors |
| DK3388075T5 (da) | 2015-03-27 | 2024-09-23 | Immatics Biotechnologies Gmbh | Hidtil ukendte peptider og kombination af peptider til anvendelse ved immunterapi mod forskellige tumorer |
| GB201505585D0 (en) | 2015-03-31 | 2015-05-13 | Immatics Biotechnologies Gmbh | Novel peptides and combination of peptides and scaffolds for use in immunotherapy against renal cell carinoma (RCC) and other cancers |
| EP4316597A2 (en) | 2017-07-07 | 2024-02-07 | immatics biotechnologies GmbH | Novel peptides and combination of peptides for use in immunotherapy against lung cancer, including nsclc, sclc and other cancers |
| US10800823B2 (en) | 2017-07-07 | 2020-10-13 | Immatics Biotechnologies Gmbh | Peptides and combination of peptides for use in immunotherapy against lung cancer, including NSCLC, SCLC and other cancers |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5331573A (en) * | 1990-12-14 | 1994-07-19 | Balaji Vitukudi N | Method of design of compounds that mimic conformational features of selected peptides |
| US5929097A (en) * | 1996-10-16 | 1999-07-27 | American Cyanamid Company | Preparation and use of ortho-sulfonamido aryl hydroxamic acids as matrix metalloproteinase and tace inhibitors |
| US6008243A (en) | 1996-10-24 | 1999-12-28 | Agouron Pharmaceuticals, Inc. | Metalloproteinase inhibitors, pharmaceutical compositions containing them, and their use |
-
2000
- 2000-02-25 US US09/514,026 patent/US6934639B1/en not_active Expired - Fee Related
-
2001
- 2001-02-16 WO PCT/US2001/005150 patent/WO2001063244A1/en not_active Application Discontinuation
- 2001-02-16 CN CN01808109A patent/CN1423748A/zh active Pending
- 2001-02-16 KR KR1020027011133A patent/KR20020089362A/ko not_active Application Discontinuation
- 2001-02-16 EA EA200200904A patent/EA200200904A1/ru unknown
- 2001-02-16 CA CA002401063A patent/CA2401063A1/en not_active Abandoned
- 2001-02-16 EP EP01912788A patent/EP1274980A4/en not_active Withdrawn
- 2001-02-16 PL PL35981901A patent/PL359819A1/xx not_active Application Discontinuation
- 2001-02-16 BR BR0108684-7A patent/BR0108684A/pt not_active IP Right Cessation
- 2001-02-16 IL IL15124201A patent/IL151242A0/xx unknown
- 2001-02-16 JP JP2001562162A patent/JP2003524176A/ja not_active Withdrawn
- 2001-02-16 AU AU2001241534A patent/AU2001241534A1/en not_active Abandoned
- 2001-02-16 HU HU0301720A patent/HUP0301720A2/hu unknown
-
2002
- 2002-08-06 ZA ZA200206248A patent/ZA200206248B/en unknown
- 2002-08-23 NO NO20024044A patent/NO20024044L/no not_active Application Discontinuation
-
2003
- 2003-06-30 HK HK03104643.0A patent/HK1052553A1/zh unknown
Also Published As
| Publication number | Publication date |
|---|---|
| BR0108684A (pt) | 2003-06-24 |
| HK1052553A1 (zh) | 2003-09-19 |
| AU2001241534A1 (en) | 2001-09-03 |
| PL359819A1 (en) | 2004-09-06 |
| ZA200206248B (en) | 2003-08-20 |
| KR20020089362A (ko) | 2002-11-29 |
| EA200200904A1 (ru) | 2003-02-27 |
| HUP0301720A2 (hu) | 2003-09-29 |
| JP2003524176A (ja) | 2003-08-12 |
| CN1423748A (zh) | 2003-06-11 |
| WO2001063244A1 (en) | 2001-08-30 |
| NO20024044D0 (no) | 2002-08-23 |
| NO20024044L (no) | 2002-10-24 |
| US6934639B1 (en) | 2005-08-23 |
| CA2401063A1 (en) | 2001-08-30 |
| EP1274980A4 (en) | 2005-02-09 |
| EP1274980A1 (en) | 2003-01-15 |
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