IL151024A0 - Conjugates of a biopolymer and a therapeutic agent - Google Patents
Conjugates of a biopolymer and a therapeutic agentInfo
- Publication number
- IL151024A0 IL151024A0 IL15102401A IL15102401A IL151024A0 IL 151024 A0 IL151024 A0 IL 151024A0 IL 15102401 A IL15102401 A IL 15102401A IL 15102401 A IL15102401 A IL 15102401A IL 151024 A0 IL151024 A0 IL 151024A0
- Authority
- IL
- Israel
- Prior art keywords
- biopolymer
- conjugates
- therapeutic agent
- therapeutic
- agent
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/61—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule the organic macromolecular compound being a polysaccharide or a derivative thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US18255800P | 2000-02-15 | 2000-02-15 | |
| US21150800P | 2000-06-14 | 2000-06-14 | |
| PCT/US2001/004925 WO2001060412A2 (en) | 2000-02-15 | 2001-02-15 | Modification of biopolymers for improved drug delivery |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL151024A0 true IL151024A0 (en) | 2003-02-12 |
Family
ID=26878197
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL15102401A IL151024A0 (en) | 2000-02-15 | 2001-02-15 | Conjugates of a biopolymer and a therapeutic agent |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP1263472A2 (en) |
| JP (1) | JP2003522806A (en) |
| AU (1) | AU2001238346A1 (en) |
| CA (1) | CA2400205A1 (en) |
| IL (1) | IL151024A0 (en) |
| WO (1) | WO2001060412A2 (en) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MXPA03006294A (en) * | 2001-01-18 | 2003-09-16 | Merck Patent Gmbh | Bifunctional fusion proteins with glucocerebrosidase activity. |
| US7723296B2 (en) | 2001-01-18 | 2010-05-25 | Genzyme Corporation | Methods for introducing mannose-6-phosphate and other oligosaccharides onto glycoproteins and its application thereof |
| WO2004060404A1 (en) * | 2002-12-27 | 2004-07-22 | Chugai Seiyaku Kabushiki Kaisha | Drug carrier |
| CA2528067C (en) | 2003-06-05 | 2015-08-04 | The Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services | Poly-gamma-glutamic acid conjugates for eliciting immune responses directed against bacilli |
| US7365223B2 (en) * | 2003-06-18 | 2008-04-29 | Nst Neurosurvival Technologies Ltd | Method for selective targeting of apoptotic cells and small molecule ligands used thereof |
| CA2542041C (en) * | 2003-10-10 | 2014-12-09 | Cellular Bioengineering, Inc. | Methods and compositions for growing corneal endothelial and related cells on biopolymers and creation of artifical corneal transplants |
| US7625736B2 (en) | 2004-06-04 | 2009-12-01 | The United States Of America As Represented By The Department Of Health And Human Services | Methods for preparing immunogenic conjugates |
| EP1790665B1 (en) | 2004-09-07 | 2014-11-05 | Chugai Seiyaku Kabushiki Kaisha | Process for producing water-soluble modified hyaluronic acid |
| JP5137814B2 (en) * | 2005-04-06 | 2013-02-06 | ジェンザイム・コーポレーション | Conjugation of PEG and polysialicosomal enzymes via acid labile linkers for therapeutic targeting |
| US20080206276A1 (en) | 2005-07-08 | 2008-08-28 | Michael Otto | Targeting Poly-Gamma-Glutamic Acid to Treat Staphylococcus Epidermidis and Related Infections |
| PT2121713E (en) | 2007-01-18 | 2013-06-25 | Genzyme Corp | Oligosaccharides comprising an aminooxy group and conjugates thereof |
| CA3040973A1 (en) | 2008-12-16 | 2010-07-01 | Genzyme Corporation | Oligosaccharide-protein conjugates |
| WO2012118189A1 (en) | 2011-03-03 | 2012-09-07 | 中外製薬株式会社 | Hyaluronic acid derivative modified by amino-carbonic acid |
| WO2012140650A2 (en) | 2011-04-12 | 2012-10-18 | Hepacore Ltd. | Conjugates of carboxy polysaccharides with fibroblast growth factors and variants thereof |
| CN104603156B (en) | 2012-09-05 | 2016-10-26 | 中外制药株式会社 | Introduce and have aminoacid and the derivatives of hyaluronic acids of steroid base |
| KR102049568B1 (en) * | 2013-04-01 | 2019-11-27 | 삼성전자주식회사 | Composition for nucleic acid delivery containing hyaluronic acid |
| GB201602359D0 (en) * | 2016-02-10 | 2016-03-23 | Medimmune Ltd | Pyrrolobenzodiazepine Conjugates |
| CN108440684A (en) * | 2018-03-22 | 2018-08-24 | 华侨大学 | A kind of NI-Cys-Alg self-assembled nanometers carrier and its preparation method and application |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1991014696A1 (en) * | 1990-03-29 | 1991-10-03 | Gilead Sciences, Inc. | Oligonucleotide-transport agent disulfide conjugates |
| US5169934A (en) * | 1990-05-14 | 1992-12-08 | Anergen, Inc. | Intracellularly cleavable compounds |
| US6335434B1 (en) * | 1998-06-16 | 2002-01-01 | Isis Pharmaceuticals, Inc., | Nucleosidic and non-nucleosidic folate conjugates |
| JP3426599B2 (en) * | 1991-11-08 | 2003-07-14 | ヘモゾル インコーポレイテッド | Hemoglobin as a drug carrier |
| US5902795A (en) | 1992-06-16 | 1999-05-11 | Trustees Of Tufts College | Oligosaccharides reactive with hyaluronan-binding protein and their methods of use |
| US5329029A (en) | 1992-11-05 | 1994-07-12 | Wan Barbara Y | Phosphatidylalkanolamine derivatives and their use in generating phospholipid conjugates |
| ATE264671T1 (en) * | 1993-02-22 | 2004-05-15 | American Bioscience Inc | METHOD FOR THE IN VIVO ADMINISTRATION OF BIOLOGICAL SUBSTANCES AND COMPOSITIONS USABLE THEREFOR |
| US5354853A (en) | 1993-03-12 | 1994-10-11 | Genzyme Corporation | Phospholipid-saccharide conjugates |
| DE69818987T2 (en) * | 1997-05-21 | 2004-07-29 | The Board Of Trustees Of The Leland Stanford Junior University, Stanford | COMPOSITION AND METHOD FOR DELAYING THE TRANSPORT BY BIOLOGICAL MEMBRANES |
| US5932552A (en) | 1997-11-26 | 1999-08-03 | Keraplast Technologies Ltd. | Keratin-based hydrogel for biomedical applications and method of production |
-
2001
- 2001-02-15 WO PCT/US2001/004925 patent/WO2001060412A2/en active Application Filing
- 2001-02-15 EP EP01910775A patent/EP1263472A2/en not_active Ceased
- 2001-02-15 IL IL15102401A patent/IL151024A0/en unknown
- 2001-02-15 CA CA002400205A patent/CA2400205A1/en not_active Abandoned
- 2001-02-15 AU AU2001238346A patent/AU2001238346A1/en not_active Abandoned
- 2001-02-15 JP JP2001559507A patent/JP2003522806A/en not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| CA2400205A1 (en) | 2001-08-23 |
| WO2001060412A2 (en) | 2001-08-23 |
| WO2001060412A3 (en) | 2002-01-24 |
| EP1263472A2 (en) | 2002-12-11 |
| AU2001238346A1 (en) | 2001-08-27 |
| JP2003522806A (en) | 2003-07-29 |
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