HK1040995A1 - 2-oxoquinoline compounds and medicinal uses thereof - Google Patents
2-oxoquinoline compounds and medicinal uses thereofInfo
- Publication number
- HK1040995A1 HK1040995A1 HK02102653.2A HK02102653A HK1040995A1 HK 1040995 A1 HK1040995 A1 HK 1040995A1 HK 02102653 A HK02102653 A HK 02102653A HK 1040995 A1 HK1040995 A1 HK 1040995A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- medicinal uses
- oxoquinoline compounds
- oxoquinoline
- compounds
- medicinal
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/22—Oxygen atoms attached in position 2 or 4
- C07D215/227—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Immunology (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Rheumatology (AREA)
- Pulmonology (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Quinoline Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP349899 | 1999-01-08 | ||
PCT/JP1999/007398 WO2000040562A1 (en) | 1999-01-08 | 1999-12-28 | 2-oxoquinoline compounds and medicinal uses thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1040995A1 true HK1040995A1 (en) | 2002-06-28 |
Family
ID=11559024
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK02102653.2A HK1040995A1 (en) | 1999-01-08 | 2002-04-09 | 2-oxoquinoline compounds and medicinal uses thereof |
Country Status (11)
Country | Link |
---|---|
US (2) | US6509352B1 (en) |
EP (1) | EP1142877A4 (en) |
JP (1) | JP2000256323A (en) |
KR (1) | KR20010101409A (en) |
CN (1) | CN1337950A (en) |
AU (1) | AU759483B2 (en) |
CA (1) | CA2358879A1 (en) |
HK (1) | HK1040995A1 (en) |
NZ (1) | NZ512883A (en) |
TW (1) | TW515794B (en) |
WO (1) | WO2000040562A1 (en) |
Families Citing this family (52)
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US6562822B2 (en) | 2000-07-12 | 2003-05-13 | Pharmacia & Upjohn Company | Heterocyle carboxamides as antiviral agents |
US6559145B2 (en) | 2000-07-12 | 2003-05-06 | Pharmacia & Upjohn Company | Heterocycle carboxamides as antiviral agents |
US6730682B2 (en) | 2000-07-12 | 2004-05-04 | Pharmacia & Upjohn Company | Heterocycle carboxamides as antiviral agents |
US8449908B2 (en) | 2000-12-22 | 2013-05-28 | Alltranz, Llc | Transdermal delivery of cannabidiol |
US6977266B2 (en) | 2000-12-28 | 2005-12-20 | Shionogi & Co., Ltd. | Pyridone derivatives having affinity for cannabinoid 2-type receptor |
JP2007191495A (en) * | 2001-10-22 | 2007-08-02 | Santen Pharmaceut Co Ltd | Pruritus treating agent |
TWI250023B (en) * | 2001-10-22 | 2006-03-01 | Santen Pharmaceutical Co Ltd | Pharmaceutical composition for itch treating agent |
WO2003061699A1 (en) * | 2001-12-27 | 2003-07-31 | Japan Tobacco, Inc. | Remedies for allergic diseases |
US20040171613A1 (en) * | 2001-12-27 | 2004-09-02 | Japan Tobacco Inc. | Therapeutic agent for non-immediate type allergic diseases |
US20050101590A1 (en) | 2002-02-19 | 2005-05-12 | Kiyoshi Yasui | Antipruritics |
AU2003217961B2 (en) | 2002-03-08 | 2008-02-28 | Signal Pharmaceuticals, Llc | Combination therapy for treating, preventing or managing proliferative disorders and cancers |
EP1606019A1 (en) * | 2003-03-07 | 2005-12-21 | The University Court of The University of Aberdeen | Cannabinoid receptor inverse agonists and neutral antagonists as therapeutic agents for the treatment of bone disorders |
WO2004104000A1 (en) * | 2003-05-23 | 2004-12-02 | Japan Tobacco Inc. | Tricyclic condensed ring compound and medical use thereof |
WO2004103974A1 (en) * | 2003-05-23 | 2004-12-02 | Japan Tobacco Inc. | Substituted 2-oxoquinoline compound and medicinal use thereof |
SI1637527T1 (en) | 2003-06-26 | 2013-07-31 | Takeda Pharmaceutical Company Limited | Cannabinoid receptor modulator |
WO2005007628A1 (en) * | 2003-07-11 | 2005-01-27 | Bristol-Myers Squibb Company | Tetrahydroquinoline derivatives as cannabinoid receptor modulators |
CN1867339A (en) * | 2003-08-18 | 2006-11-22 | 盐野义制药株式会社 | Novel use of cannabinoid receptor agonist |
TW200508211A (en) * | 2003-08-26 | 2005-03-01 | Shionogi & Co | 2-naphthylimino-1,3-thiazine derivatives |
CN1875021A (en) * | 2003-11-04 | 2006-12-06 | 默克公司 | Substituted naphthyridinone derivatives |
GB0403864D0 (en) * | 2004-02-20 | 2004-03-24 | Ucl Ventures | Modulator |
WO2006115509A2 (en) | 2004-06-24 | 2006-11-02 | Novartis Vaccines And Diagnostics Inc. | Small molecule immunopotentiators and assays for their detection |
TWI360539B (en) | 2004-10-28 | 2012-03-21 | Shionogi & Co | 3-carbamoyl-2-pyridone derivatives |
WO2006054912A1 (en) * | 2004-11-18 | 2006-05-26 | Obchestvo S Ogranichennoy Otvetstvennost'u 'asineks Medhim' | Aryl(hetaryl)-3-aminomethyl-quinilone-2 derivatives in the form of no-synthetase i and cyclooxygenase-2 nhibitors, methods for the production thereof and compositions based thereon |
KR20070084531A (en) * | 2004-11-24 | 2007-08-24 | 머크 앤드 캄파니 인코포레이티드 | Liquid and semi-solid pharmaceutical formulations for oral administration of a substituted amide |
WO2006076568A2 (en) | 2005-01-12 | 2006-07-20 | Bristol-Myers Squibb Company | Thiazolopyridines as cannabinoid receptor modulators |
WO2006076597A1 (en) * | 2005-01-12 | 2006-07-20 | Bristol-Myers Squibb Company | Bicyclic heterocycles as cannabinoid receptor modulators |
GB0519760D0 (en) * | 2005-09-28 | 2005-11-09 | Glaxo Group Ltd | Novel compounds |
EP2112927A4 (en) * | 2006-06-08 | 2010-01-20 | Mor Research Applic Ltd | Method for treatment of overfiltering and leaking blebs with sterile talc |
US20080161340A1 (en) * | 2006-12-20 | 2008-07-03 | Cara Therapeutics, Inc. | Tetrahydroquinilinones, tetrahydronaphthyridones and derivatives thereof |
GB0702862D0 (en) * | 2007-02-14 | 2007-03-28 | Univ Aberdeen | Therapeutic compounds |
JPWO2008111296A1 (en) * | 2007-03-09 | 2010-06-24 | 国立大学法人京都大学 | Pharmaceuticals for the prevention and treatment of skin diseases caused by increased keratinization |
CL2008001631A1 (en) * | 2007-06-06 | 2009-01-02 | Smithkline Beecham Corp | Compounds derived from substituted heterocycles, with the presence of a phenoxy group, reverse transcriptase inhibitors; pharmaceutical composition; and use in the treatment of HIV viral infections. |
ES2534900T3 (en) * | 2007-07-30 | 2015-04-30 | Zynerba Pharmaceuticals, Inc. | Cannabidiol prodrugs, compositions comprising cannabidiol prodrugs and methods of use thereof |
WO2009053799A1 (en) * | 2007-10-24 | 2009-04-30 | Glenmark Pharmaceuticals, S.A. | Novel cannabinoid receptor ligands, pharmaceutical compositions containing them, and process for their preparation |
IE20070928A1 (en) * | 2007-12-21 | 2009-09-30 | Giuliani Int Ltd | Multi target ligands |
US20090247619A1 (en) * | 2008-03-06 | 2009-10-01 | University Of Kentucky | Cannabinoid-Containing Compositions and Methods for Their Use |
EP2365749A4 (en) * | 2008-11-13 | 2012-05-30 | Merck Sharp & Dohme | Quinolone neuropeptide s receptor antagonists |
EP2311443A1 (en) | 2009-10-15 | 2011-04-20 | Rheinische Friedrich-Wilhelms-Universität | Pharmaceutical composition containing cannabinoid-receptor 2 antagonists |
AU2011295405B2 (en) | 2010-08-27 | 2015-01-22 | Grünenthal GmbH | Substituted 2-oxy-quinoline-3-carboxamides as KCNQ2/3 modulators |
AR082734A1 (en) | 2010-08-27 | 2012-12-26 | Gruenenthal Gmbh | QUINOLINO-3-SUBSTITUTED CARBOXAMIDS AS MODULATORS OF KCNQ2 / 3 |
TW201211007A (en) | 2010-08-27 | 2012-03-16 | Gruenenthal Gmbh | Substituted 2-amino-quinoline-3-carboxamides as KCNQ2/3 modulators |
US8653102B2 (en) * | 2010-08-27 | 2014-02-18 | Gruenenthal Gmbh | Substituted 2-oxo- and 2-thioxo-dihydroquinoline-3-carboxamides as KCNQ2/3 modulators |
US8618129B2 (en) | 2010-09-01 | 2013-12-31 | Gruenenthal Gmbh | Substituted 1-oxo-dihydroisoquinoline-3-carboxamides as KCNQ2/3 modulators |
AU2011314411B2 (en) | 2010-10-14 | 2014-06-12 | Immunahr Ab | 1,2-dihydro-4-hydroxy-2-oxo-quinoline-3-carboxanilides as AhR activators. |
WO2012164085A1 (en) | 2011-06-03 | 2012-12-06 | Merz Pharma Gmbh & Co. Kgaa | Glycine b antagonists |
EP3327004B1 (en) * | 2015-07-17 | 2020-11-04 | Fujifilm Corporation | Nitrogen-containing heterocyclic compound |
CA3021660A1 (en) | 2016-04-22 | 2017-10-26 | Receptor Life Sciences, Inc. | Fast-acting plant-based medicinal compounds and nutritional supplements |
EA201892396A1 (en) | 2016-12-02 | 2019-04-30 | Ресептор Лайф Сайенсиз, Инк. | QUICKLY PRODUCTIVE PLANT MEDICINES AND BIOLOGICALLY ACTIVE ADDITIVES |
JP6768083B2 (en) | 2016-12-27 | 2020-10-14 | 富士フイルム株式会社 | Antitumor agents and bromodomain inhibitors |
KR20190133667A (en) * | 2017-03-24 | 2019-12-03 | 다이쇼 세이야꾸 가부시끼가이샤 | 2 (1H) -quinolinone derivative |
AU2020253293A1 (en) * | 2019-03-29 | 2021-10-07 | The Scripps Research Institute | Benzopyrane and imidazole derivatives useful for the stabilization of amyloidogenic immunoglobulin light chains |
WO2020248908A1 (en) * | 2019-06-10 | 2020-12-17 | 中国科学院广州生物医药与健康研究院 | Bifunctional immunomodulator, and pharmaceutically acceptable salt and pharmaceutical composition thereof |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2377400A2 (en) | 1977-01-18 | 1978-08-11 | Roussel Uclaf | Analgesic hydroxy:quinoline carboxamide cpds. - esp. N-(2-thiazolyl)-carboxamide cpds. with 8-tri:fluoro:methyl substit. |
IE52670B1 (en) | 1981-03-03 | 1988-01-20 | Leo Ab | Heterocyclic carboxamides,compositions containing such compounds,and processes for their preparation |
DE3134780A1 (en) * | 1981-09-02 | 1983-03-10 | Hoechst Ag, 6000 Frankfurt | "SULFONYL UREAS, METHOD FOR THE PRODUCTION THEREOF, PHARMACEUTICAL PREPARATIONS BASED ON THESE COMPOUNDS AND THEIR USE" |
PT79699B (en) | 1983-12-22 | 1986-12-10 | Pfizer | Process for preparing quinolone inotropic agents |
SE8902076D0 (en) | 1989-06-09 | 1989-06-09 | Pharmacia Ab | DERIVATIVES OF QUINOLINE-3-CARBOXANILIDE |
GB9108547D0 (en) | 1991-04-22 | 1991-06-05 | Fujisawa Pharmaceutical Co | Quinoline derivatives |
WO1996005166A1 (en) | 1994-08-11 | 1996-02-22 | Yamanouchi Pharmaceutical Co., Ltd. | Substituted amine derivative and medicinal composition containing the same |
WO1997029079A1 (en) | 1996-02-06 | 1997-08-14 | Japan Tobacco Inc. | Novel compounds and pharmaceutical use thereof |
KR20010021696A (en) | 1997-07-11 | 2001-03-15 | 미즈노 마사루 | Quinoline compounds and medicinal uses thereof |
EP1048655B1 (en) * | 1997-12-03 | 2004-09-01 | Taisho Pharmaceutical Co., Ltd | 1,2-dihydro-2-oxoquinoline derivatives |
-
1999
- 1999-12-27 JP JP11368621A patent/JP2000256323A/en active Pending
- 1999-12-28 US US09/869,895 patent/US6509352B1/en not_active Expired - Fee Related
- 1999-12-28 WO PCT/JP1999/007398 patent/WO2000040562A1/en not_active Application Discontinuation
- 1999-12-28 EP EP99961472A patent/EP1142877A4/en not_active Withdrawn
- 1999-12-28 NZ NZ512883A patent/NZ512883A/en active Application Filing
- 1999-12-28 CN CN99816363A patent/CN1337950A/en active Pending
- 1999-12-28 CA CA002358879A patent/CA2358879A1/en not_active Abandoned
- 1999-12-28 KR KR1020017008594A patent/KR20010101409A/en not_active Application Discontinuation
- 1999-12-28 AU AU18041/00A patent/AU759483B2/en not_active Ceased
- 1999-12-30 TW TW088123313A patent/TW515794B/en not_active IP Right Cessation
-
2002
- 2002-04-09 HK HK02102653.2A patent/HK1040995A1/en unknown
- 2002-09-16 US US10/245,861 patent/US6806276B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
JP2000256323A (en) | 2000-09-19 |
AU759483B2 (en) | 2003-04-17 |
CA2358879A1 (en) | 2000-07-13 |
US20030191069A1 (en) | 2003-10-09 |
US6509352B1 (en) | 2003-01-21 |
KR20010101409A (en) | 2001-11-14 |
AU1804100A (en) | 2000-07-24 |
CN1337950A (en) | 2002-02-27 |
NZ512883A (en) | 2003-03-28 |
TW515794B (en) | 2003-01-01 |
US6806276B2 (en) | 2004-10-19 |
EP1142877A4 (en) | 2003-03-12 |
WO2000040562A1 (en) | 2000-07-13 |
EP1142877A1 (en) | 2001-10-10 |
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