HK1040995A1 - 2-oxoquinoline compounds and medicinal uses thereof - Google Patents

2-oxoquinoline compounds and medicinal uses thereof

Info

Publication number
HK1040995A1
HK1040995A1 HK02102653.2A HK02102653A HK1040995A1 HK 1040995 A1 HK1040995 A1 HK 1040995A1 HK 02102653 A HK02102653 A HK 02102653A HK 1040995 A1 HK1040995 A1 HK 1040995A1
Authority
HK
Hong Kong
Prior art keywords
medicinal uses
oxoquinoline compounds
oxoquinoline
compounds
medicinal
Prior art date
Application number
HK02102653.2A
Other languages
Chinese (zh)
Inventor
Inaba Takashi
Kaya Tetsudo
Iwamura Hiroyuki
Original Assignee
Japan Tobacco Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Japan Tobacco Inc filed Critical Japan Tobacco Inc
Publication of HK1040995A1 publication Critical patent/HK1040995A1/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20Oxygen atoms
    • C07D215/22Oxygen atoms attached in position 2 or 4
    • C07D215/227Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 2
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Rheumatology (AREA)
  • Pulmonology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Quinoline Compounds (AREA)
HK02102653.2A 1999-01-08 2002-04-09 2-oxoquinoline compounds and medicinal uses thereof HK1040995A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP349899 1999-01-08
PCT/JP1999/007398 WO2000040562A1 (en) 1999-01-08 1999-12-28 2-oxoquinoline compounds and medicinal uses thereof

Publications (1)

Publication Number Publication Date
HK1040995A1 true HK1040995A1 (en) 2002-06-28

Family

ID=11559024

Family Applications (1)

Application Number Title Priority Date Filing Date
HK02102653.2A HK1040995A1 (en) 1999-01-08 2002-04-09 2-oxoquinoline compounds and medicinal uses thereof

Country Status (11)

Country Link
US (2) US6509352B1 (en)
EP (1) EP1142877A4 (en)
JP (1) JP2000256323A (en)
KR (1) KR20010101409A (en)
CN (1) CN1337950A (en)
AU (1) AU759483B2 (en)
CA (1) CA2358879A1 (en)
HK (1) HK1040995A1 (en)
NZ (1) NZ512883A (en)
TW (1) TW515794B (en)
WO (1) WO2000040562A1 (en)

Families Citing this family (52)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6562822B2 (en) 2000-07-12 2003-05-13 Pharmacia & Upjohn Company Heterocyle carboxamides as antiviral agents
US6559145B2 (en) 2000-07-12 2003-05-06 Pharmacia & Upjohn Company Heterocycle carboxamides as antiviral agents
US6730682B2 (en) 2000-07-12 2004-05-04 Pharmacia & Upjohn Company Heterocycle carboxamides as antiviral agents
US8449908B2 (en) 2000-12-22 2013-05-28 Alltranz, Llc Transdermal delivery of cannabidiol
US6977266B2 (en) 2000-12-28 2005-12-20 Shionogi & Co., Ltd. Pyridone derivatives having affinity for cannabinoid 2-type receptor
JP2007191495A (en) * 2001-10-22 2007-08-02 Santen Pharmaceut Co Ltd Pruritus treating agent
TWI250023B (en) * 2001-10-22 2006-03-01 Santen Pharmaceutical Co Ltd Pharmaceutical composition for itch treating agent
WO2003061699A1 (en) * 2001-12-27 2003-07-31 Japan Tobacco, Inc. Remedies for allergic diseases
US20040171613A1 (en) * 2001-12-27 2004-09-02 Japan Tobacco Inc. Therapeutic agent for non-immediate type allergic diseases
US20050101590A1 (en) 2002-02-19 2005-05-12 Kiyoshi Yasui Antipruritics
AU2003217961B2 (en) 2002-03-08 2008-02-28 Signal Pharmaceuticals, Llc Combination therapy for treating, preventing or managing proliferative disorders and cancers
EP1606019A1 (en) * 2003-03-07 2005-12-21 The University Court of The University of Aberdeen Cannabinoid receptor inverse agonists and neutral antagonists as therapeutic agents for the treatment of bone disorders
WO2004104000A1 (en) * 2003-05-23 2004-12-02 Japan Tobacco Inc. Tricyclic condensed ring compound and medical use thereof
WO2004103974A1 (en) * 2003-05-23 2004-12-02 Japan Tobacco Inc. Substituted 2-oxoquinoline compound and medicinal use thereof
SI1637527T1 (en) 2003-06-26 2013-07-31 Takeda Pharmaceutical Company Limited Cannabinoid receptor modulator
WO2005007628A1 (en) * 2003-07-11 2005-01-27 Bristol-Myers Squibb Company Tetrahydroquinoline derivatives as cannabinoid receptor modulators
CN1867339A (en) * 2003-08-18 2006-11-22 盐野义制药株式会社 Novel use of cannabinoid receptor agonist
TW200508211A (en) * 2003-08-26 2005-03-01 Shionogi & Co 2-naphthylimino-1,3-thiazine derivatives
CN1875021A (en) * 2003-11-04 2006-12-06 默克公司 Substituted naphthyridinone derivatives
GB0403864D0 (en) * 2004-02-20 2004-03-24 Ucl Ventures Modulator
WO2006115509A2 (en) 2004-06-24 2006-11-02 Novartis Vaccines And Diagnostics Inc. Small molecule immunopotentiators and assays for their detection
TWI360539B (en) 2004-10-28 2012-03-21 Shionogi & Co 3-carbamoyl-2-pyridone derivatives
WO2006054912A1 (en) * 2004-11-18 2006-05-26 Obchestvo S Ogranichennoy Otvetstvennost'u 'asineks Medhim' Aryl(hetaryl)-3-aminomethyl-quinilone-2 derivatives in the form of no-synthetase i and cyclooxygenase-2 nhibitors, methods for the production thereof and compositions based thereon
KR20070084531A (en) * 2004-11-24 2007-08-24 머크 앤드 캄파니 인코포레이티드 Liquid and semi-solid pharmaceutical formulations for oral administration of a substituted amide
WO2006076568A2 (en) 2005-01-12 2006-07-20 Bristol-Myers Squibb Company Thiazolopyridines as cannabinoid receptor modulators
WO2006076597A1 (en) * 2005-01-12 2006-07-20 Bristol-Myers Squibb Company Bicyclic heterocycles as cannabinoid receptor modulators
GB0519760D0 (en) * 2005-09-28 2005-11-09 Glaxo Group Ltd Novel compounds
EP2112927A4 (en) * 2006-06-08 2010-01-20 Mor Research Applic Ltd Method for treatment of overfiltering and leaking blebs with sterile talc
US20080161340A1 (en) * 2006-12-20 2008-07-03 Cara Therapeutics, Inc. Tetrahydroquinilinones, tetrahydronaphthyridones and derivatives thereof
GB0702862D0 (en) * 2007-02-14 2007-03-28 Univ Aberdeen Therapeutic compounds
JPWO2008111296A1 (en) * 2007-03-09 2010-06-24 国立大学法人京都大学 Pharmaceuticals for the prevention and treatment of skin diseases caused by increased keratinization
CL2008001631A1 (en) * 2007-06-06 2009-01-02 Smithkline Beecham Corp Compounds derived from substituted heterocycles, with the presence of a phenoxy group, reverse transcriptase inhibitors; pharmaceutical composition; and use in the treatment of HIV viral infections.
ES2534900T3 (en) * 2007-07-30 2015-04-30 Zynerba Pharmaceuticals, Inc. Cannabidiol prodrugs, compositions comprising cannabidiol prodrugs and methods of use thereof
WO2009053799A1 (en) * 2007-10-24 2009-04-30 Glenmark Pharmaceuticals, S.A. Novel cannabinoid receptor ligands, pharmaceutical compositions containing them, and process for their preparation
IE20070928A1 (en) * 2007-12-21 2009-09-30 Giuliani Int Ltd Multi target ligands
US20090247619A1 (en) * 2008-03-06 2009-10-01 University Of Kentucky Cannabinoid-Containing Compositions and Methods for Their Use
EP2365749A4 (en) * 2008-11-13 2012-05-30 Merck Sharp & Dohme Quinolone neuropeptide s receptor antagonists
EP2311443A1 (en) 2009-10-15 2011-04-20 Rheinische Friedrich-Wilhelms-Universität Pharmaceutical composition containing cannabinoid-receptor 2 antagonists
AU2011295405B2 (en) 2010-08-27 2015-01-22 Grünenthal GmbH Substituted 2-oxy-quinoline-3-carboxamides as KCNQ2/3 modulators
AR082734A1 (en) 2010-08-27 2012-12-26 Gruenenthal Gmbh QUINOLINO-3-SUBSTITUTED CARBOXAMIDS AS MODULATORS OF KCNQ2 / 3
TW201211007A (en) 2010-08-27 2012-03-16 Gruenenthal Gmbh Substituted 2-amino-quinoline-3-carboxamides as KCNQ2/3 modulators
US8653102B2 (en) * 2010-08-27 2014-02-18 Gruenenthal Gmbh Substituted 2-oxo- and 2-thioxo-dihydroquinoline-3-carboxamides as KCNQ2/3 modulators
US8618129B2 (en) 2010-09-01 2013-12-31 Gruenenthal Gmbh Substituted 1-oxo-dihydroisoquinoline-3-carboxamides as KCNQ2/3 modulators
AU2011314411B2 (en) 2010-10-14 2014-06-12 Immunahr Ab 1,2-dihydro-4-hydroxy-2-oxo-quinoline-3-carboxanilides as AhR activators.
WO2012164085A1 (en) 2011-06-03 2012-12-06 Merz Pharma Gmbh & Co. Kgaa Glycine b antagonists
EP3327004B1 (en) * 2015-07-17 2020-11-04 Fujifilm Corporation Nitrogen-containing heterocyclic compound
CA3021660A1 (en) 2016-04-22 2017-10-26 Receptor Life Sciences, Inc. Fast-acting plant-based medicinal compounds and nutritional supplements
EA201892396A1 (en) 2016-12-02 2019-04-30 Ресептор Лайф Сайенсиз, Инк. QUICKLY PRODUCTIVE PLANT MEDICINES AND BIOLOGICALLY ACTIVE ADDITIVES
JP6768083B2 (en) 2016-12-27 2020-10-14 富士フイルム株式会社 Antitumor agents and bromodomain inhibitors
KR20190133667A (en) * 2017-03-24 2019-12-03 다이쇼 세이야꾸 가부시끼가이샤 2 (1H) -quinolinone derivative
AU2020253293A1 (en) * 2019-03-29 2021-10-07 The Scripps Research Institute Benzopyrane and imidazole derivatives useful for the stabilization of amyloidogenic immunoglobulin light chains
WO2020248908A1 (en) * 2019-06-10 2020-12-17 中国科学院广州生物医药与健康研究院 Bifunctional immunomodulator, and pharmaceutically acceptable salt and pharmaceutical composition thereof

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2377400A2 (en) 1977-01-18 1978-08-11 Roussel Uclaf Analgesic hydroxy:quinoline carboxamide cpds. - esp. N-(2-thiazolyl)-carboxamide cpds. with 8-tri:fluoro:methyl substit.
IE52670B1 (en) 1981-03-03 1988-01-20 Leo Ab Heterocyclic carboxamides,compositions containing such compounds,and processes for their preparation
DE3134780A1 (en) * 1981-09-02 1983-03-10 Hoechst Ag, 6000 Frankfurt "SULFONYL UREAS, METHOD FOR THE PRODUCTION THEREOF, PHARMACEUTICAL PREPARATIONS BASED ON THESE COMPOUNDS AND THEIR USE"
PT79699B (en) 1983-12-22 1986-12-10 Pfizer Process for preparing quinolone inotropic agents
SE8902076D0 (en) 1989-06-09 1989-06-09 Pharmacia Ab DERIVATIVES OF QUINOLINE-3-CARBOXANILIDE
GB9108547D0 (en) 1991-04-22 1991-06-05 Fujisawa Pharmaceutical Co Quinoline derivatives
WO1996005166A1 (en) 1994-08-11 1996-02-22 Yamanouchi Pharmaceutical Co., Ltd. Substituted amine derivative and medicinal composition containing the same
WO1997029079A1 (en) 1996-02-06 1997-08-14 Japan Tobacco Inc. Novel compounds and pharmaceutical use thereof
KR20010021696A (en) 1997-07-11 2001-03-15 미즈노 마사루 Quinoline compounds and medicinal uses thereof
EP1048655B1 (en) * 1997-12-03 2004-09-01 Taisho Pharmaceutical Co., Ltd 1,2-dihydro-2-oxoquinoline derivatives

Also Published As

Publication number Publication date
JP2000256323A (en) 2000-09-19
AU759483B2 (en) 2003-04-17
CA2358879A1 (en) 2000-07-13
US20030191069A1 (en) 2003-10-09
US6509352B1 (en) 2003-01-21
KR20010101409A (en) 2001-11-14
AU1804100A (en) 2000-07-24
CN1337950A (en) 2002-02-27
NZ512883A (en) 2003-03-28
TW515794B (en) 2003-01-01
US6806276B2 (en) 2004-10-19
EP1142877A4 (en) 2003-03-12
WO2000040562A1 (en) 2000-07-13
EP1142877A1 (en) 2001-10-10

Similar Documents

Publication Publication Date Title
HK1040995A1 (en) 2-oxoquinoline compounds and medicinal uses thereof
PL351387A1 (en) Pharmaceutical composition
HUP0200548A2 (en) Pharmaceutical compositions and their use
HK1044476A1 (en) Medicinal compositions
HUP0201952A2 (en) Androgen compounds and pharmaceutical compounds containing the same
EP1166786A4 (en) Medicinal compositions
HUP0203896A3 (en) Substituted 8-arylquinoline phosphodiesterase-4-inhibitors and use thereof
EG23858A (en) Drug combination
AU2002218502A1 (en) Lactam compounds and medicinal use thereof
HUP0200055A3 (en) 16-hydroxyestrienes and pharmaceutical compositions containing the same
GB9930079D0 (en) Medicaments
GB0023323D0 (en) Arylhydantoin derivatives and uses thereof
GB9930071D0 (en) Medicaments
AU1053501A (en) Polyazanaphthalene compound and medicinal use thereof
GB9924990D0 (en) Medicaments
GB9930083D0 (en) Medicaments
GB9930082D0 (en) Medicaments
GB9929040D0 (en) Medicaments
GB9929039D0 (en) Medicaments
GB9904935D0 (en) Medicaments
GB9828707D0 (en) Pharmaceutical uses
GB9909843D0 (en) Compounds and their use
IL149638A0 (en) S-allylmercaptoglutathione and uses thereof
GB9911499D0 (en) Medicament
GB9929405D0 (en) Medicament