IL150181A0 - Quaternary ammonnium and their-tussive agent - Google Patents

Quaternary ammonnium and their-tussive agent

Info

Publication number
IL150181A0
IL150181A0 IL15018100A IL15018100A IL150181A0 IL 150181 A0 IL150181 A0 IL 150181A0 IL 15018100 A IL15018100 A IL 15018100A IL 15018100 A IL15018100 A IL 15018100A IL 150181 A0 IL150181 A0 IL 150181A0
Authority
IL
Israel
Prior art keywords
ammonnium
quaternary
sup
tussive agent
compounds
Prior art date
Application number
IL15018100A
Other languages
English (en)
Original Assignee
Ucb Farchim Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ucb Farchim Sa filed Critical Ucb Farchim Sa
Publication of IL150181A0 publication Critical patent/IL150181A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/14—Quaternary ammonium compounds, e.g. edrophonium, choline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/14—Antitussive agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/02—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C217/04—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C217/06—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted
    • C07C217/14—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to a carbon atom of a six-membered aromatic ring
    • C07C217/18—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to a carbon atom of a six-membered aromatic ring the six-membered aromatic ring or condensed ring system containing that ring being further substituted
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/02—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C217/04—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C217/28—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines
    • C07C217/30—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines having the oxygen atom of at least one of the etherified hydroxy groups further bound to a carbon atom of a six-membered aromatic ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Nutrition Science (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Indole Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
IL15018100A 1999-12-15 2000-12-15 Quaternary ammonnium and their-tussive agent IL150181A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CA2292343 1999-12-15
PCT/CA2000/001508 WO2001044167A1 (fr) 1999-12-15 2000-12-15 Composes d'ammonium quaternaire et leur utilisation comme agent antitussif

Publications (1)

Publication Number Publication Date
IL150181A0 true IL150181A0 (en) 2002-12-01

Family

ID=4164883

Family Applications (1)

Application Number Title Priority Date Filing Date
IL15018100A IL150181A0 (en) 1999-12-15 2000-12-15 Quaternary ammonnium and their-tussive agent

Country Status (22)

Country Link
US (2) US20030181489A1 (fr)
EP (1) EP1254104B1 (fr)
JP (1) JP2003517034A (fr)
KR (1) KR20020092352A (fr)
CN (1) CN1423630A (fr)
AT (1) ATE293097T1 (fr)
AU (1) AU2334701A (fr)
BG (1) BG106815A (fr)
BR (1) BR0016427A (fr)
CZ (1) CZ20022097A3 (fr)
DE (1) DE60019465D1 (fr)
EE (1) EE200200315A (fr)
HU (1) HUP0203918A3 (fr)
IL (1) IL150181A0 (fr)
IS (1) IS6416A (fr)
MX (1) MXPA02006049A (fr)
NO (1) NO20022868L (fr)
NZ (1) NZ519747A (fr)
PL (1) PL355944A1 (fr)
RU (1) RU2002116212A (fr)
WO (1) WO2001044167A1 (fr)
ZA (1) ZA200205567B (fr)

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2703324A (en) * 1950-08-30 1955-03-01 Bristol Lab Inc Basic ethers of aralkyl phenols and salts thereof
US2642434A (en) * 1951-09-05 1953-06-16 Sterling Drug Inc Quaternary ammonium salts of lower alkyl 4-substituted-2-(tertiaryaminoalkoxy) benzoates and their preparation
US2913459A (en) * 1954-12-09 1959-11-17 Eprova Ltd New quaternary ammonium compounds and process for the production thereof
GB919126A (en) * 1958-07-01 1963-02-20 Wellcome Found Quaternary ammonium compounds and their preparation
GB935613A (en) * 1960-02-04 1963-08-28 Wellcome Found Quaternary ammonium compounds and their preparation
US3840666A (en) * 1972-07-05 1974-10-08 Univ Michigan Anti-arrhythmic quaternary salt compositions and methods of use
US4048335A (en) * 1974-06-17 1977-09-13 The Regents Of The University Of Michigan Method of inhibiting myocardial ischemia in mammals using quaternary salts
DE2940765A1 (de) * 1979-10-08 1981-04-23 Basf Ag, 6700 Ludwigshafen Substituierte alkylammoniumsalze, ihre herstellung, ihre verwendung zur regulierung des pflanzenwachstums und mittel dafuer
CN1145608C (zh) * 1998-06-09 2004-04-14 诺特兰药品有限公司 作为镇咳剂的季铵化合物

Also Published As

Publication number Publication date
ZA200205567B (en) 2003-10-13
DE60019465D1 (de) 2005-05-19
EP1254104B1 (fr) 2005-04-13
HUP0203918A3 (en) 2005-06-28
WO2001044167A1 (fr) 2001-06-21
RU2002116212A (ru) 2004-02-10
MXPA02006049A (es) 2004-08-23
ATE293097T1 (de) 2005-04-15
US20050197383A1 (en) 2005-09-08
JP2003517034A (ja) 2003-05-20
BG106815A (en) 2003-04-30
CZ20022097A3 (cs) 2002-11-13
NZ519747A (en) 2003-08-29
EE200200315A (et) 2003-08-15
AU2334701A (en) 2001-06-25
PL355944A1 (en) 2004-05-31
US20030181489A1 (en) 2003-09-25
IS6416A (is) 2002-06-12
NO20022868D0 (no) 2002-06-14
EP1254104A1 (fr) 2002-11-06
KR20020092352A (ko) 2002-12-11
HUP0203918A2 (hu) 2003-03-28
CN1423630A (zh) 2003-06-11
WO2001044167A8 (fr) 2001-12-06
BR0016427A (pt) 2002-10-29
NO20022868L (no) 2002-08-14

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