BR0016427A - Método para o tratamento e/ou prevenção da tosse em um animal de sangue quente, uso de um composto, composto, e, composição farmacêutica - Google Patents
Método para o tratamento e/ou prevenção da tosse em um animal de sangue quente, uso de um composto, composto, e, composição farmacêuticaInfo
- Publication number
- BR0016427A BR0016427A BR0016427-5A BR0016427A BR0016427A BR 0016427 A BR0016427 A BR 0016427A BR 0016427 A BR0016427 A BR 0016427A BR 0016427 A BR0016427 A BR 0016427A
- Authority
- BR
- Brazil
- Prior art keywords
- compound
- cough
- warm
- prevention
- treatment
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 5
- 206010011224 Cough Diseases 0.000 title abstract 3
- 241001465754 Metazoa Species 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 230000002265 prevention Effects 0.000 title abstract 2
- 239000004480 active ingredient Substances 0.000 abstract 1
- 239000008280 blood Substances 0.000 abstract 1
- 210000004369 blood Anatomy 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 150000003856 quaternary ammonium compounds Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/14—Quaternary ammonium compounds, e.g. edrophonium, choline
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/14—Antitussive agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
- C07C217/02—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C217/04—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C217/06—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted
- C07C217/14—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to a carbon atom of a six-membered aromatic ring
- C07C217/18—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to a carbon atom of a six-membered aromatic ring the six-membered aromatic ring or condensed ring system containing that ring being further substituted
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
- C07C217/02—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C217/04—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C217/28—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines
- C07C217/30—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines having the oxygen atom of at least one of the etherified hydroxy groups further bound to a carbon atom of a six-membered aromatic ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Nutrition Science (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
- Indole Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
"MéTODO PARA O TRATAMENTO E/OU PREVENçãO DA TOSSE EM UM ANIMAL DE SANGUE QUENTE, USO DE UM COMPOSTO, COMPOSTO, E, COMPOSIçãO FARMACêUTICA". Em um aspecto, a presente invenção diz respeito ao uso de certos compostos de amónio quaternário como ingrediente ativo na fabricação de um medicamento para o uso no tratamento e/ou prevenção da tosse em animais de sangue quente, incluindo seres humanos, tais como os compostos da fórmula Y-J-E An^ -^ (I) em que J é independentemente selecionado de um grupo representado por uma das fórmulas (II), (III) e (IV).
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CA2292343 | 1999-12-15 | ||
PCT/CA2000/001508 WO2001044167A1 (en) | 1999-12-15 | 2000-12-15 | Quaternary ammonium compounds and their use as anti-tussive agents |
Publications (1)
Publication Number | Publication Date |
---|---|
BR0016427A true BR0016427A (pt) | 2002-10-29 |
Family
ID=4164883
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR0016427-5A BR0016427A (pt) | 1999-12-15 | 2000-12-15 | Método para o tratamento e/ou prevenção da tosse em um animal de sangue quente, uso de um composto, composto, e, composição farmacêutica |
Country Status (22)
Country | Link |
---|---|
US (2) | US20030181489A1 (pt) |
EP (1) | EP1254104B1 (pt) |
JP (1) | JP2003517034A (pt) |
KR (1) | KR20020092352A (pt) |
CN (1) | CN1423630A (pt) |
AT (1) | ATE293097T1 (pt) |
AU (1) | AU2334701A (pt) |
BG (1) | BG106815A (pt) |
BR (1) | BR0016427A (pt) |
CZ (1) | CZ20022097A3 (pt) |
DE (1) | DE60019465D1 (pt) |
EE (1) | EE200200315A (pt) |
HU (1) | HUP0203918A3 (pt) |
IL (1) | IL150181A0 (pt) |
IS (1) | IS6416A (pt) |
MX (1) | MXPA02006049A (pt) |
NO (1) | NO20022868L (pt) |
NZ (1) | NZ519747A (pt) |
PL (1) | PL355944A1 (pt) |
RU (1) | RU2002116212A (pt) |
WO (1) | WO2001044167A1 (pt) |
ZA (1) | ZA200205567B (pt) |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2703324A (en) * | 1950-08-30 | 1955-03-01 | Bristol Lab Inc | Basic ethers of aralkyl phenols and salts thereof |
US2642434A (en) * | 1951-09-05 | 1953-06-16 | Sterling Drug Inc | Quaternary ammonium salts of lower alkyl 4-substituted-2-(tertiaryaminoalkoxy) benzoates and their preparation |
US2913459A (en) * | 1954-12-09 | 1959-11-17 | Eprova Ltd | New quaternary ammonium compounds and process for the production thereof |
GB919126A (en) * | 1958-07-01 | 1963-02-20 | Wellcome Found | Quaternary ammonium compounds and their preparation |
GB935613A (en) * | 1960-02-04 | 1963-08-28 | Wellcome Found | Quaternary ammonium compounds and their preparation |
US3840666A (en) * | 1972-07-05 | 1974-10-08 | Univ Michigan | Anti-arrhythmic quaternary salt compositions and methods of use |
US4048335A (en) * | 1974-06-17 | 1977-09-13 | The Regents Of The University Of Michigan | Method of inhibiting myocardial ischemia in mammals using quaternary salts |
DE2940765A1 (de) * | 1979-10-08 | 1981-04-23 | Basf Ag, 6700 Ludwigshafen | Substituierte alkylammoniumsalze, ihre herstellung, ihre verwendung zur regulierung des pflanzenwachstums und mittel dafuer |
KR20010072591A (ko) * | 1998-06-09 | 2001-07-31 | 추후보정 | 4급 암모늄 화합물 진해제 |
-
2000
- 2000-12-15 MX MXPA02006049A patent/MXPA02006049A/es unknown
- 2000-12-15 EE EEP200200315A patent/EE200200315A/xx unknown
- 2000-12-15 BR BR0016427-5A patent/BR0016427A/pt not_active IP Right Cessation
- 2000-12-15 EP EP00986919A patent/EP1254104B1/en not_active Expired - Lifetime
- 2000-12-15 KR KR1020027007715A patent/KR20020092352A/ko not_active Application Discontinuation
- 2000-12-15 PL PL00355944A patent/PL355944A1/xx not_active Application Discontinuation
- 2000-12-15 IL IL15018100A patent/IL150181A0/xx unknown
- 2000-12-15 CZ CZ20022097A patent/CZ20022097A3/cs unknown
- 2000-12-15 JP JP2001545256A patent/JP2003517034A/ja active Pending
- 2000-12-15 DE DE60019465T patent/DE60019465D1/de not_active Expired - Lifetime
- 2000-12-15 US US10/149,668 patent/US20030181489A1/en not_active Abandoned
- 2000-12-15 NZ NZ519747A patent/NZ519747A/xx unknown
- 2000-12-15 WO PCT/CA2000/001508 patent/WO2001044167A1/en active IP Right Grant
- 2000-12-15 AT AT00986919T patent/ATE293097T1/de not_active IP Right Cessation
- 2000-12-15 CN CN00818439A patent/CN1423630A/zh active Pending
- 2000-12-15 RU RU2002116212/14A patent/RU2002116212A/ru not_active Application Discontinuation
- 2000-12-15 HU HU0203918A patent/HUP0203918A3/hu unknown
- 2000-12-15 AU AU23347/01A patent/AU2334701A/en not_active Abandoned
-
2002
- 2002-06-12 BG BG106815A patent/BG106815A/xx unknown
- 2002-06-12 IS IS6416A patent/IS6416A/is unknown
- 2002-06-14 NO NO20022868A patent/NO20022868L/no not_active Application Discontinuation
- 2002-07-11 ZA ZA200205567A patent/ZA200205567B/xx unknown
-
2005
- 2005-04-26 US US11/115,633 patent/US20050197383A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
NO20022868L (no) | 2002-08-14 |
KR20020092352A (ko) | 2002-12-11 |
HUP0203918A2 (hu) | 2003-03-28 |
CN1423630A (zh) | 2003-06-11 |
RU2002116212A (ru) | 2004-02-10 |
US20030181489A1 (en) | 2003-09-25 |
JP2003517034A (ja) | 2003-05-20 |
NZ519747A (en) | 2003-08-29 |
EE200200315A (et) | 2003-08-15 |
HUP0203918A3 (en) | 2005-06-28 |
AU2334701A (en) | 2001-06-25 |
DE60019465D1 (de) | 2005-05-19 |
IS6416A (is) | 2002-06-12 |
WO2001044167A1 (en) | 2001-06-21 |
PL355944A1 (en) | 2004-05-31 |
CZ20022097A3 (cs) | 2002-11-13 |
EP1254104A1 (en) | 2002-11-06 |
BG106815A (en) | 2003-04-30 |
IL150181A0 (en) | 2002-12-01 |
US20050197383A1 (en) | 2005-09-08 |
ZA200205567B (en) | 2003-10-13 |
EP1254104B1 (en) | 2005-04-13 |
WO2001044167A8 (en) | 2001-12-06 |
NO20022868D0 (no) | 2002-06-14 |
MXPA02006049A (es) | 2004-08-23 |
ATE293097T1 (de) | 2005-04-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 5A, 6A E 7A ANUIDADES. |
|
B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 1929 DE 26/12/2007. |