IL149158A0 - Tailored peptide synthetases, a method for their production and the use thereof - Google Patents
Tailored peptide synthetases, a method for their production and the use thereofInfo
- Publication number
- IL149158A0 IL149158A0 IL14915800A IL14915800A IL149158A0 IL 149158 A0 IL149158 A0 IL 149158A0 IL 14915800 A IL14915800 A IL 14915800A IL 14915800 A IL14915800 A IL 14915800A IL 149158 A0 IL149158 A0 IL 149158A0
- Authority
- IL
- Israel
- Prior art keywords
- peptide synthetases
- production
- nrpss
- modification
- peptides
- Prior art date
Links
- 108700018928 Peptide Synthases Proteins 0.000 title abstract 2
- 102000056222 Peptide Synthases Human genes 0.000 title abstract 2
- 108010019477 S-adenosyl-L-methionine-dependent N-methyltransferase Proteins 0.000 abstract 3
- 108010000785 non-ribosomal peptide synthase Proteins 0.000 abstract 3
- 230000004048 modification Effects 0.000 abstract 2
- 238000012986 modification Methods 0.000 abstract 2
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 2
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 2
- 150000001413 amino acids Chemical class 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 238000010276 construction Methods 0.000 abstract 1
- 230000004927 fusion Effects 0.000 abstract 1
- 210000003705 ribosome Anatomy 0.000 abstract 1
- 238000003786 synthesis reaction Methods 0.000 abstract 1
- 230000002194 synthesizing effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/93—Ligases (6)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Peptides Or Proteins (AREA)
- Enzymes And Modification Thereof (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19951196A DE19951196A1 (de) | 1999-10-22 | 1999-10-22 | Massgeschneiderte Peptidsynthetasen und ihre Verwendung |
| PCT/EP2000/010250 WO2001030985A1 (de) | 1999-10-22 | 2000-10-18 | Massgeschneiderte peptidsynthetasen, verfahren zu ihrer herstellung und ihre verwendung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL149158A0 true IL149158A0 (en) | 2002-11-10 |
Family
ID=7926708
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL14915800A IL149158A0 (en) | 1999-10-22 | 2000-10-18 | Tailored peptide synthetases, a method for their production and the use thereof |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US20100285563A1 (da) |
| EP (1) | EP1255816B1 (da) |
| JP (1) | JP2003512835A (da) |
| KR (1) | KR20020069509A (da) |
| AT (1) | ATE331027T1 (da) |
| AU (1) | AU1139901A (da) |
| CA (1) | CA2384972A1 (da) |
| DE (2) | DE19951196A1 (da) |
| DK (1) | DK1255816T3 (da) |
| ES (1) | ES2267579T3 (da) |
| IL (1) | IL149158A0 (da) |
| NO (1) | NO20021810L (da) |
| WO (1) | WO2001030985A1 (da) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2003060128A2 (en) * | 2001-12-26 | 2003-07-24 | Ecopia Biosciences Inc. | Compositions, methods and systems for discovery of lipopeptides |
| US7235651B2 (en) | 2001-12-26 | 2007-06-26 | Cubist Pharmaceuticals, Inc. | Genes and proteins involved in the biosynthesis of lipopeptides |
| KR100762315B1 (ko) * | 2006-01-24 | 2007-10-04 | 한국생명공학연구원 | 푸자리시딘 생합성 효소 및 이를 코딩하는 유전자 |
| US7981685B2 (en) * | 2007-04-16 | 2011-07-19 | Modular Genetics, Inc. | Generation of acyl amino acids |
| HK1201877A1 (en) | 2012-01-31 | 2015-09-11 | 灿盛制药有限公司荷兰公司 | Mbth-like proteins in the production of semi synthetic antibiotics |
| US11371066B2 (en) | 2015-07-13 | 2022-06-28 | Modular Genetics, Inc. | Generation of acyl alcohols |
| WO2017020983A1 (en) | 2015-08-05 | 2017-02-09 | Merck Patent Gmbh | Artificial non-ribosomal peptide synthetases |
| EP3414323A1 (en) | 2016-02-08 | 2018-12-19 | Johann Wolfgang Goethe-Universität Frankfurt am Main | Artificial non-ribosomal peptide synthases and their use |
| EP3511445A1 (en) | 2018-01-15 | 2019-07-17 | Johann Wolfgang Goethe-Universität Frankfurt | System for the assembly and modification of non-ribosomal peptide synthases |
| CN114657155B (zh) * | 2021-12-23 | 2024-01-19 | 中国农业科学院生物技术研究所 | 一种新型的非核糖体多肽合成酶拆分表达方法 |
| EP4573192A1 (en) | 2022-08-16 | 2025-06-25 | Johann-Wolfgang-Goethe-Universität Frankfurt am Main | Method and means for engineering non-ribosomal peptides |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1264712B1 (it) * | 1993-07-13 | 1996-10-04 | Eniricerche Spa | Metodo di sintesi biologica di peptidi |
| DE19531944A1 (de) * | 1995-08-18 | 1997-02-20 | Biopract Gmbh | Neue Endo-Xylanasen |
| DE19909146A1 (de) * | 1999-03-03 | 2000-09-28 | Mohamed A Marahiel | Verfahren zur gezielten biologischen Synthese von Peptiden |
-
1999
- 1999-10-22 DE DE19951196A patent/DE19951196A1/de not_active Ceased
-
2000
- 2000-10-18 WO PCT/EP2000/010250 patent/WO2001030985A1/de not_active Ceased
- 2000-10-18 DE DE50013072T patent/DE50013072D1/de not_active Expired - Lifetime
- 2000-10-18 ES ES00972794T patent/ES2267579T3/es not_active Expired - Lifetime
- 2000-10-18 IL IL14915800A patent/IL149158A0/xx unknown
- 2000-10-18 JP JP2001533968A patent/JP2003512835A/ja active Pending
- 2000-10-18 AT AT00972794T patent/ATE331027T1/de not_active IP Right Cessation
- 2000-10-18 AU AU11399/01A patent/AU1139901A/en not_active Abandoned
- 2000-10-18 KR KR1020027005167A patent/KR20020069509A/ko not_active Withdrawn
- 2000-10-18 DK DK00972794T patent/DK1255816T3/da active
- 2000-10-18 EP EP00972794A patent/EP1255816B1/de not_active Expired - Lifetime
- 2000-10-18 CA CA002384972A patent/CA2384972A1/en not_active Abandoned
-
2002
- 2002-04-17 NO NO20021810A patent/NO20021810L/no not_active Application Discontinuation
-
2010
- 2010-06-21 US US12/819,751 patent/US20100285563A1/en not_active Abandoned
- 2010-06-21 US US12/819,762 patent/US20100297751A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US20100285563A1 (en) | 2010-11-11 |
| EP1255816B1 (de) | 2006-06-21 |
| KR20020069509A (ko) | 2002-09-04 |
| EP1255816A1 (de) | 2002-11-13 |
| NO20021810D0 (no) | 2002-04-17 |
| US20100297751A1 (en) | 2010-11-25 |
| DK1255816T3 (da) | 2006-10-30 |
| DE19951196A1 (de) | 2001-05-10 |
| JP2003512835A (ja) | 2003-04-08 |
| DE50013072D1 (de) | 2006-08-03 |
| WO2001030985A1 (de) | 2001-05-03 |
| ATE331027T1 (de) | 2006-07-15 |
| AU1139901A (en) | 2001-05-08 |
| CA2384972A1 (en) | 2001-05-03 |
| NO20021810L (no) | 2002-06-19 |
| ES2267579T3 (es) | 2007-03-16 |
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