IL148008A0 - Conditional immortalisation of cells - Google Patents

Conditional immortalisation of cells

Info

Publication number
IL148008A0
IL148008A0 IL14800800A IL14800800A IL148008A0 IL 148008 A0 IL148008 A0 IL 148008A0 IL 14800800 A IL14800800 A IL 14800800A IL 14800800 A IL14800800 A IL 14800800A IL 148008 A0 IL148008 A0 IL 148008A0
Authority
IL
Israel
Prior art keywords
cells
recombinant
conditional immortalisation
immortalisation
conditional
Prior art date
Application number
IL14800800A
Other languages
English (en)
Original Assignee
Reneuron Ltd
Ludwig Inst For Cancer Res Imp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Reneuron Ltd, Ludwig Inst For Cancer Res Imp filed Critical Reneuron Ltd
Publication of IL148008A0 publication Critical patent/IL148008A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1241—Nucleotidyltransferases (2.7.7)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/82—Translation products from oncogenes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2799/00—Uses of viruses
    • C12N2799/02—Uses of viruses as vector
    • C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
    • C12N2799/027—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from a retrovirus

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Neurosurgery (AREA)
  • Microbiology (AREA)
  • Oncology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
IL14800800A 1999-09-17 2000-09-18 Conditional immortalisation of cells IL148008A0 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP99307405 1999-09-17
US09/663,537 US6399384B1 (en) 1999-09-17 2000-09-15 Conditional immortalization of cells
PCT/GB2000/003588 WO2001021790A1 (fr) 1999-09-17 2000-09-18 Immortalisation conditionnelle de cellules

Publications (1)

Publication Number Publication Date
IL148008A0 true IL148008A0 (en) 2002-09-12

Family

ID=26153574

Family Applications (1)

Application Number Title Priority Date Filing Date
IL14800800A IL148008A0 (en) 1999-09-17 2000-09-18 Conditional immortalisation of cells

Country Status (11)

Country Link
US (1) US6399384B1 (fr)
EP (1) EP1212420B1 (fr)
JP (1) JP2003510046A (fr)
CN (1) CN1373804A (fr)
AT (1) ATE297987T1 (fr)
AU (1) AU757816B2 (fr)
CA (1) CA2383253A1 (fr)
DE (1) DE60020855T2 (fr)
ES (1) ES2241652T3 (fr)
IL (1) IL148008A0 (fr)
WO (1) WO2001021790A1 (fr)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9518606D0 (en) * 1995-09-12 1995-11-15 Inst Of Psychiatry Neural transplantation
GB9907243D0 (en) * 1999-03-29 1999-05-26 Reneuron Ltd Therapy
GB0005856D0 (en) * 2000-03-10 2000-05-03 Reneuron Ltd Genetic constructs
DE10019195B4 (de) * 2000-04-17 2006-03-09 Heart Biosystems Gmbh Reversible Immortalisierung
US20040170955A1 (en) * 2000-09-08 2004-09-02 Wadih Arap Human and mouse targeting peptides identified by phage display
US7452964B2 (en) 2001-09-07 2008-11-18 Board Of Regents, The University Of Texas System Compositions and methods of use of targeting peptides against placenta and adipose tissues
US7420030B2 (en) 2000-09-08 2008-09-02 The Board Of Regents Of The University Of Texas System Aminopeptidase A (APA) targeting peptides for the treatment of cancer
US20050074747A1 (en) * 2000-09-08 2005-04-07 Wadih Arap Biopanning and rapid analysis of selective interactive ligands (brasil)
EP1207196A1 (fr) * 2000-10-27 2002-05-22 Societe Des Produits Nestle S.A. Preosteoblastes immortalisees et leurs procede de production
EP1418932A4 (fr) * 2001-07-18 2006-03-15 Univ Texas Etat anti-angiogene chez les souris et les etres humains souffrant d'une degenerescence cellulaire du photorecepteur retinien
US8507445B2 (en) * 2001-09-07 2013-08-13 Board Of Regents, The University Of Texas System Compositions and methods of use of targeting peptides for diagnosis and therapy of human cancer
US7671010B2 (en) * 2002-08-30 2010-03-02 The Board Of Regents Of The University Of Texas System Compositions and methods of use of targeting peptides for diagnosis and therapy of human cancer
US20040048243A1 (en) * 2001-09-07 2004-03-11 Wadih Arap Methods and compositions for in vitro targeting
GB0125773D0 (en) * 2001-10-26 2001-12-19 Reneuron Ltd Constructs
JPWO2003038076A1 (ja) * 2001-10-31 2005-02-24 株式会社レノメディクス研究所 不死化間葉系細胞及びその利用
DE60334533D1 (de) * 2002-03-15 2010-11-25 Univ Duke Gewebe-engineering
AU2004231094A1 (en) * 2003-04-14 2004-10-28 Board Of Regents, The University Of Texas System Methods for ex vivo hybridoma-free production of polyclonal and monoclonal antibodies and generation of immortalized cell populations
AU2004272340B2 (en) * 2003-09-12 2008-01-03 Dana Farber Cancer Institute Immortalisation of mammalian cells and therapeutic applications of said cells
US20050193432A1 (en) * 2003-11-18 2005-09-01 Whitehead Institute For Biomedical Research Xenograft model of functional normal and malignant human breast tissues in rodents and methods thereof
DK1645626T3 (da) * 2004-09-30 2008-01-21 Reneuron Ltd Cellelinie
US20090298095A1 (en) * 2005-04-15 2009-12-03 The John Hopkins University Immortalization of cells including neuronal cells
NZ569816A (en) * 2005-12-16 2011-10-28 Ribovax Biotechnologies Sa Methods for obtaining immortalized antibody secreting cells
GB0822246D0 (en) 2008-12-05 2009-01-14 Reneuron Ltd Composition
GB0902034D0 (en) 2009-02-06 2009-03-11 Reneuron Ltd Method
EP2380905A1 (fr) 2010-04-19 2011-10-26 Thrombotargets Europe, S.L. Vésicules enrichies de phospholipides portant un facteur tissulaire doté d'activités hémostatiques et utilisations correspondantes
CN105176913A (zh) * 2015-09-23 2015-12-23 扬州大学 一种奶牛乳腺上皮细胞永生化方法
JP2022513490A (ja) * 2018-12-16 2022-02-08 フィジーン、エルエルシー 遺伝子編集線維芽細胞の治療的使用
GB202005494D0 (en) 2020-04-15 2020-05-27 Reneuron Ltd Induced pluripotent cell comprising a contollable transgene for conditional immortalisation

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5270191A (en) * 1988-04-12 1993-12-14 Massachusetts Institute Of Technology Method for manipulation of the cell types of eukaryotes
US5766948A (en) 1993-01-06 1998-06-16 The Regents Of The University Of California Method for production of neuroblasts
EP0799315A2 (fr) 1994-12-19 1997-10-08 Cold Spring Harbor Laboratory Fraction proteinique de la telomerase
GB9518606D0 (en) 1995-09-12 1995-11-15 Inst Of Psychiatry Neural transplantation
DE69739497D1 (de) * 1996-10-01 2009-08-27 Geron Corp Menschlische Telomerase katalytische Untereinheit
WO1998037181A2 (fr) 1997-02-20 1998-08-27 Whitehead Institute For Biomedical Research Gene de sous-unite catalytique de telomerase et proteine codee

Also Published As

Publication number Publication date
CA2383253A1 (fr) 2001-03-29
AU7301500A (en) 2001-04-24
JP2003510046A (ja) 2003-03-18
EP1212420B1 (fr) 2005-06-15
DE60020855D1 (de) 2005-07-21
US6399384B1 (en) 2002-06-04
CN1373804A (zh) 2002-10-09
ES2241652T3 (es) 2005-11-01
AU757816B2 (en) 2003-03-06
DE60020855T2 (de) 2006-05-04
ATE297987T1 (de) 2005-07-15
WO2001021790A1 (fr) 2001-03-29
EP1212420A1 (fr) 2002-06-12

Similar Documents

Publication Publication Date Title
IL148008A0 (en) Conditional immortalisation of cells
AU4221399A (en) Human cd45+ and/or fibroblast + mesenchymal stem cells
IL148060A0 (en) Compositions and methods for improved cell culture
IL148512A0 (en) Methods for making recombinant proteins using apoptosis inhibitors
IL137946A0 (en) Intracardiac cell delivery and cell transplantation
WO1998006747A3 (en) Uses for wnt polypeptides
MXPA03007829A (es) Catodos de pila de combustible novedosos y sus pilas de combustible.
EP0953354A4 (fr) Agents de proliferation des cellules souches hematopoietiques
EP0456640A4 (fr) Cellules endotheliales modifiees par genie genetique et utilisation de ces cellules.
IL144654A0 (en) Pancreatic progenitor cells, methods and uses related thereto
GB2392674B (en) Mesenchymal cells and osteoblasts from human embryonic stem cell
MXPA02004882A (es) Genes de desarrollo de la planta.
EP1439226A3 (fr) Séquence antisens de heparanase
AU9582398A (en) Methods and devices for the long-term culture of hematopoietic progenitor cells
MXPA02003733A (es) Metodos para producir celulas progenitoras diferenciadas y celulas troncales embrionicas de lineas de descendencia defectivas.
EP1447443A4 (fr) Cellules mesenchymateuses immortalisees et leur utilisation
ATE342275T1 (de) Vorübergehend-immortalisierte zellen zur verwendung in gentherapie
EP1157118A4 (fr) Polynucleotide codant pour un polypeptide ayant une activite d'heparanase et expression de ce polynucleotide dans des cellules genetiquement modifiees
EP1233058A4 (fr) Methode de proliferation de cellules tueuses naturelles
GB9825096D0 (en) Cells,culture methods and their uses
ATE226087T1 (de) Verwendung von neuen zelltod inducierenden mitteln im synergismus mit interferon
AU2002303277A1 (en) Artificial chromosomes that can shuttle between bacteria, yeast, and mammalian cells
MXPA02002653A (es) Clonacion de cerdos usando celulas donadoras o nucleos a partir de celulas diferenciadas y produccion de porcinos pluripotentes.
DE69737597D1 (de) Vektoren zur inhibierung von viralem und tumorwachstum
ZA200202481B (en) Recombinant adenoviruses preparation and adenovirus banks.

Legal Events

Date Code Title Description
KB Patent renewed