IL146567A0 - Oil-core particles containing a hydrophobic core material and hydrophobic drug and method for the preparation thereof - Google Patents

Oil-core particles containing a hydrophobic core material and hydrophobic drug and method for the preparation thereof

Info

Publication number
IL146567A0
IL146567A0 IL14656700A IL14656700A IL146567A0 IL 146567 A0 IL146567 A0 IL 146567A0 IL 14656700 A IL14656700 A IL 14656700A IL 14656700 A IL14656700 A IL 14656700A IL 146567 A0 IL146567 A0 IL 146567A0
Authority
IL
Israel
Prior art keywords
hydrophobic
oil
preparation
particles containing
core material
Prior art date
Application number
IL14656700A
Other languages
English (en)
Original Assignee
Skyepharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Skyepharma Inc filed Critical Skyepharma Inc
Publication of IL146567A0 publication Critical patent/IL146567A0/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/107Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1617Organic compounds, e.g. phospholipids, fats
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682Processes
    • A61K9/1694Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00Anaesthetics

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Dispersion Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Anesthesiology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
IL14656700A 1999-06-04 2000-06-02 Oil-core particles containing a hydrophobic core material and hydrophobic drug and method for the preparation thereof IL146567A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US13766999P 1999-06-04 1999-06-04
PCT/US2000/015401 WO2000074653A1 (fr) 1999-06-04 2000-06-02 Compositions a noyau huileux destinees a la liberation prolongee de medicaments hydrophobes

Publications (1)

Publication Number Publication Date
IL146567A0 true IL146567A0 (en) 2002-07-25

Family

ID=22478531

Family Applications (1)

Application Number Title Priority Date Filing Date
IL14656700A IL146567A0 (en) 1999-06-04 2000-06-02 Oil-core particles containing a hydrophobic core material and hydrophobic drug and method for the preparation thereof

Country Status (8)

Country Link
US (1) US20030211140A1 (fr)
EP (1) EP1189597A4 (fr)
JP (1) JP2003501376A (fr)
AU (1) AU763945B2 (fr)
CA (1) CA2375371A1 (fr)
IL (1) IL146567A0 (fr)
NZ (1) NZ515644A (fr)
WO (1) WO2000074653A1 (fr)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2001254995A1 (en) * 2000-05-15 2001-11-26 Vectura Limited Method of manufacturing particles
US20030157247A1 (en) * 2000-06-14 2003-08-21 Yoshiro Chikami Method for producing coated bioactive granule
KR100533458B1 (ko) 2002-07-20 2005-12-07 대화제약 주식회사 파클리탁셀의 가용화용 조성물 및 그의 제조 방법
JP4886297B2 (ja) 2002-11-01 2012-02-29 バイオデリバリー サイエンシーズ インターナショナル インコーポレイティッド ジオデート送達媒体
US20060134145A1 (en) * 2002-12-06 2006-06-22 Otsuka Pharmaceutical Factory, Inc. Propofol-containing fat emulsions
JP5285275B2 (ja) * 2004-09-17 2013-09-11 デュレクト コーポレーション 制御されたデリバリーシステム
US9486408B2 (en) 2005-12-01 2016-11-08 University Of Massachusetts Lowell Botulinum nanoemulsions
US20100183726A1 (en) * 2006-08-02 2010-07-22 Robert Nicolosi Compositions and methods for treating cancer with dacarbazine nanoemulsions
JP5193870B2 (ja) * 2006-09-05 2013-05-08 キユーピー株式会社 プロスタグランジン脂肪乳剤およびその製造方法、ならびにその安定化方法および乳化剤
BRPI0719732A2 (pt) 2006-12-01 2017-05-16 Anterios Inc nanopartículas de peptídeo e usos para as mesmas
EP2494958A1 (fr) 2006-12-01 2012-09-05 Anterios, Inc. Nanoparticules d'entité amphiphile
GB0707612D0 (en) * 2007-04-19 2007-05-30 Stratosphere Pharma Ab Cores and microcapsules suitable for parenteral administration as well as process for their manufacture
ES2660906T3 (es) 2007-05-31 2018-03-26 Anterios, Inc. Nanopartículas de ácido nucleico y usos de las mismas
WO2009039628A1 (fr) 2007-09-27 2009-04-02 Immunovaccine Technologies Inc. Utilisation de liposomes dans un véhicule composant une phase hydrophobe continue pour la délivrance de polynucléotides in vivo
CA2723918C (fr) 2008-06-05 2018-01-09 Immunovaccine Technologies Inc. Compositions contenant des liposomes, un antigene, un polynucleotide et un transporteur comprenant une phase continue d'une substance hydrophobe
SG11201401177WA (en) 2011-10-06 2014-04-28 Immunovaccine Technologies Inc Liposome compositions comprising an adjuvant that activates or increases the activity of tlr2 and uses thereof
RU2678433C2 (ru) 2012-05-10 2019-01-29 Пейнреформ Лтд. Депо-составы гидрофобного активного ингредиента и способы их получения
US10775533B2 (en) * 2016-02-12 2020-09-15 Purdue Research Foundation Methods of forming particulate films and films and devices made therefrom
KR102487144B1 (ko) 2016-11-21 2023-01-12 에이리온 테라퓨틱스, 인코포레이티드 큰 물질의 경피 전달
JP7219344B2 (ja) * 2019-01-07 2023-02-07 プサン ナショナル ユニバーシティ インダストリー-ユニバーシティ コーポレーション ファウンデーション 血液脳関門の透過性を増進させるw/o/w型トリオレインエマルジョンを利用した薬物伝達プラットホーム
WO2020223813A1 (fr) * 2019-05-07 2020-11-12 University Health Network Nanoémulsion à enveloppe de porphyrine
KR20220140711A (ko) 2020-01-13 2022-10-18 듀렉트 코퍼레이션 불순물이 감소된 지속 방출 약물 전달 시스템 및 관련 방법

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA735221B (en) * 1972-08-07 1974-07-31 Upjohn Co Improved dosage regimen
US4610868A (en) * 1984-03-20 1986-09-09 The Liposome Company, Inc. Lipid matrix carriers for use in drug delivery systems
AU587472B2 (en) * 1985-05-22 1989-08-17 Liposome Technology, Inc. Liposome inhalation method and system
US5227165A (en) * 1989-11-13 1993-07-13 Nova Pharmaceutical Corporation Liposphere delivery systems for local anesthetics
US5576016A (en) * 1993-05-18 1996-11-19 Pharmos Corporation Solid fat nanoemulsions as drug delivery vehicles
US5672358A (en) * 1994-06-21 1997-09-30 Ascent Pharmaceuticals, Inc. Controlled release aqueous emulsion
US5616330A (en) * 1994-07-19 1997-04-01 Hemagen/Pfc Stable oil-in-water emulsions incorporating a taxine (taxol) and method of making same
TW497974B (en) * 1996-07-03 2002-08-11 Res Dev Foundation High dose liposomal aerosol formulations
US5891467A (en) * 1997-01-31 1999-04-06 Depotech Corporation Method for utilizing neutral lipids to modify in vivo release from multivesicular liposomes
CA2564120C (fr) * 1997-01-31 2010-04-13 Skyepharma Inc. Procede servant a utiliser des lipides neutres afin de modifier la liberation in vivo depuis des liposomes a vesicules multiples
PT1014946E (pt) * 1997-09-18 2010-07-06 Pacira Pharmaceuticals Inc COMPOSIÎES ANESTéSICAS LIPOSSOMAIS DE LIBERTAÆO SUSTENTADA
US6063762A (en) * 1997-12-05 2000-05-16 Chong Kun Dang Corp. Cyclosporin-containing microemulsion preconcentrate composition
AU757686B2 (en) * 1998-03-31 2003-03-06 New York University Liposomal bupivacaine compositions and methods of preparation

Also Published As

Publication number Publication date
US20030211140A1 (en) 2003-11-13
NZ515644A (en) 2004-12-24
JP2003501376A (ja) 2003-01-14
CA2375371A1 (fr) 2000-12-14
EP1189597A4 (fr) 2008-06-18
AU6048000A (en) 2000-12-28
WO2000074653A1 (fr) 2000-12-14
AU763945B2 (en) 2003-08-07
EP1189597A1 (fr) 2002-03-27

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