IL146182A0 - Recombinant adenoviruses for the sodium/iodide symporter (nis) - Google Patents
Recombinant adenoviruses for the sodium/iodide symporter (nis)Info
- Publication number
- IL146182A0 IL146182A0 IL14618200A IL14618200A IL146182A0 IL 146182 A0 IL146182 A0 IL 146182A0 IL 14618200 A IL14618200 A IL 14618200A IL 14618200 A IL14618200 A IL 14618200A IL 146182 A0 IL146182 A0 IL 146182A0
- Authority
- IL
- Israel
- Prior art keywords
- nis
- sodium
- recombinant adenoviruses
- iodide symporter
- symporter
- Prior art date
Links
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 title 1
- 102000003673 Symporters Human genes 0.000 title 1
- 108090000088 Symporters Proteins 0.000 title 1
- XMBWDFGMSWQBCA-UHFFFAOYSA-N hydrogen iodide Chemical compound I XMBWDFGMSWQBCA-UHFFFAOYSA-N 0.000 title 1
- 229910052708 sodium Inorganic materials 0.000 title 1
- 239000011734 sodium Substances 0.000 title 1
- 241000701161 unidentified adenovirus Species 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/10011—Adenoviridae
- C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
- C12N2710/10341—Use of virus, viral particle or viral elements as a vector
- C12N2710/10343—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2800/00—Nucleic acids vectors
- C12N2800/10—Plasmid DNA
- C12N2800/108—Plasmid DNA episomal vectors
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Biotechnology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- Virology (AREA)
- Cell Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Gastroenterology & Hepatology (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9907449A FR2794771B1 (fr) | 1999-06-11 | 1999-06-11 | Adenovirus recombinants codant pour le transporteur specifique de l'iode (nis) |
PCT/FR2000/001594 WO2000076450A2 (fr) | 1999-06-11 | 2000-06-08 | Adenovirus recombinants codant pour le transporteur specifique de l'iode (nis) |
Publications (1)
Publication Number | Publication Date |
---|---|
IL146182A0 true IL146182A0 (en) | 2002-07-25 |
Family
ID=9546704
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL14618200A IL146182A0 (en) | 1999-06-11 | 2000-06-08 | Recombinant adenoviruses for the sodium/iodide symporter (nis) |
Country Status (13)
Country | Link |
---|---|
US (2) | US20100080775A1 (xx) |
EP (1) | EP1187919B1 (xx) |
JP (2) | JP2003501107A (xx) |
KR (1) | KR100708949B1 (xx) |
CN (1) | CN1259418C (xx) |
AU (1) | AU782934B2 (xx) |
CA (1) | CA2376735A1 (xx) |
DE (1) | DE60037189T2 (xx) |
FR (1) | FR2794771B1 (xx) |
HU (1) | HUP0201455A3 (xx) |
IL (1) | IL146182A0 (xx) |
MX (1) | MXPA01012004A (xx) |
WO (1) | WO2000076450A2 (xx) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2794771B1 (fr) * | 1999-06-11 | 2001-08-10 | Aventis Pharma Sa | Adenovirus recombinants codant pour le transporteur specifique de l'iode (nis) |
US6586411B1 (en) | 2000-08-16 | 2003-07-01 | Mayo Foundation For Medical Education And Research | System for monitoring the location of transgenes |
US6896881B1 (en) | 1999-09-24 | 2005-05-24 | Mayo Foundation For Medical Education And Research | Therapeutic methods and compositions using viruses of the recombinant paramyxoviridae family |
US7118740B1 (en) | 2000-09-22 | 2006-10-10 | Mayo Foundation For Medical Education And Research | Method for limiting the growth of cancer cells using an attenuated measles virus |
FR2837492B1 (fr) * | 2002-03-21 | 2007-07-20 | Commissariat Energie Atomique | Transporteur apical d'iode et ses applications |
JP5213075B2 (ja) | 2007-06-15 | 2013-06-19 | ジェネラックス・コーポレイション | 腫瘍の画像化および/または処置のための微生物 |
CN102344489B (zh) * | 2010-08-05 | 2014-02-26 | 中国医药大学 | 经修饰的钠碘共同转运蛋白质及其应用 |
US9951117B2 (en) | 2010-09-02 | 2018-04-24 | Mayo Foundation For Medical Education And Research | Vesicular stomatitis viruses |
CA2847413C (en) | 2010-09-02 | 2018-05-22 | Mayo Foundation For Medical Education And Research | Vesicular stomatitis viruses |
WO2012142529A2 (en) | 2011-04-15 | 2012-10-18 | Genelux Corporation | Clonal strains of attenuated vaccinia viruses and methods of use thereof |
US8859256B2 (en) | 2011-10-05 | 2014-10-14 | Genelux Corporation | Method for detecting replication or colonization of a biological therapeutic |
TWI583224B (zh) * | 2015-03-12 | 2017-05-11 | 柯彥均 | 訊息之即時通訊方法 |
CA3013637A1 (en) | 2016-02-23 | 2017-08-31 | Salk Institute For Biological Studies | High throughput assay for measuring adenovirus replication kinetics |
AU2017223589B2 (en) | 2016-02-23 | 2023-08-03 | Salk Institute For Biological Studies | Exogenous gene expression in therapeutic adenovirus for minimal impact on viral kinetics |
WO2018111767A1 (en) | 2016-12-12 | 2018-06-21 | Salk Institute For Biological Studies | Tumor-targeting synthetic adenoviruses and uses thereof |
Family Cites Families (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2601676B1 (fr) * | 1986-07-17 | 1988-09-23 | Rhone Poulenc Sante | Procede de preparation du taxol et du desacetyl-10 taxol |
FR2601675B1 (fr) * | 1986-07-17 | 1988-09-23 | Rhone Poulenc Sante | Derives du taxol, leur preparation et les compositions pharmaceutiques qui les contiennent |
FR2629818B1 (fr) * | 1988-04-06 | 1990-11-16 | Centre Nat Rech Scient | Procede de preparation du taxol |
FR2662440B1 (fr) * | 1990-05-22 | 1992-07-31 | Rhone Poulenc Sante | Procede de preparation stereoselective de derives de la phenylisoserine. |
FR2662441B1 (fr) | 1990-05-22 | 1992-10-23 | Rhone Poulenc Sante | Procede de preparation enantioselective de derives de la phenylisoserine. |
WO1993000926A1 (en) | 1991-07-02 | 1993-01-21 | Children's Medical Center Corporation | Treatment of periodontal disease with protease inhibitors |
FR2678833B1 (fr) | 1991-07-08 | 1995-04-07 | Rhone Poulenc Rorer Sa | Nouvelles compositions pharmaceutiques a base de derives de la classe des taxanes. |
FR2698543B1 (fr) * | 1992-12-02 | 1994-12-30 | Rhone Poulenc Rorer Sa | Nouvelles compositions à base de taxoides. |
FR2698871B1 (fr) * | 1992-12-09 | 1995-02-24 | Rhone Poulenc Rorer Sa | Nouveau taxoïdes, leur préparation et les compositions pharmaceutiques qui les contiennent. |
FR2705361B1 (fr) | 1993-05-18 | 1995-08-04 | Centre Nat Rech Scient | Vecteurs viraux et utilisation en thérapie génique. |
FR2705686B1 (fr) * | 1993-05-28 | 1995-08-18 | Transgene Sa | Nouveaux adénovirus défectifs et lignées de complémentation correspondantes. |
FR2706486B1 (fr) | 1993-06-16 | 1995-09-01 | Rhone Poulenc Rorer Sa | Séquences nucléiques, vecteurs les contenant, compositions pharmaceutiques et utilisations thérapeutiques. |
RU2219241C2 (ru) | 1993-07-13 | 2003-12-20 | Рон-Пуленк Роре С.А. | Дефектный рекомбинантный аденовирусный вектор (варианты) |
WO1995003400A1 (en) | 1993-07-23 | 1995-02-02 | Johns Hopkins University School Of Medicine | Recombinationally targeted cloning in yeast artificial chromosomes |
US7252989B1 (en) | 1994-04-04 | 2007-08-07 | Board Of Regents, The University Of Texas System | Adenovirus supervector system |
FR2722191B1 (fr) | 1994-07-08 | 1996-08-23 | Rhone Poulenc Rorer Sa | Procede de preparation du trihydrate du (2r,3s)-3-tertbutoxycarbonylamino-2-hydroxy-3-phenylpropionate de 4-acetoxy2alpha-benzoyloxy-5beta,20epoxy-1,7beta,10beta trihydroxy-9-oxo-tax-11-en-13alpha-yle |
FR2724945B1 (fr) | 1994-09-27 | 1996-12-27 | Centre Nat Rech Scient | Vecteurs viraux et utilisation en therapie genique |
IL116816A (en) | 1995-01-20 | 2003-05-29 | Rhone Poulenc Rorer Sa | Cell for the production of a defective recombinant adenovirus or an adeno-associated virus and the various uses thereof |
FR2730504B1 (fr) | 1995-02-13 | 1997-03-28 | Rhone Poulenc Rorer Sa | Procede de preparation de genomes d'adenovirus recombinants |
US5652224A (en) * | 1995-02-24 | 1997-07-29 | The Trustees Of The University Of Pennsylvania | Methods and compositions for gene therapy for the treatment of defects in lipoprotein metabolism |
US5863904A (en) * | 1995-09-26 | 1999-01-26 | The University Of Michigan | Methods for treating cancers and restenosis with P21 |
WO1998037190A1 (en) * | 1997-02-20 | 1998-08-27 | Hepavec Aktiengesellschaft Für Gentherapie | Method for induction of apoptotic cell death in malignant cells, through reduction of the rb to apoptosis inducing proteins ratio |
JP2001523103A (ja) * | 1997-04-28 | 2001-11-20 | ローヌ−プーラン・ロレ・エス・アー | 腫瘍治療用血管形成アンタゴニストのアデノウイルスによる腫瘍内送達 |
US6022708A (en) * | 1998-02-26 | 2000-02-08 | Genentech, Inc. | Fused |
FR2778670B1 (fr) | 1998-05-18 | 2002-12-13 | Rhone Poulenc Rorer Sa | Methodes et compositions pour la production de particules virales |
KR20020013464A (ko) | 1998-08-27 | 2002-02-20 | 추후제출 | 이종 유전자의 전달을 위한 표적화된 아데노바이러스 벡터 |
FR2794771B1 (fr) | 1999-06-11 | 2001-08-10 | Aventis Pharma Sa | Adenovirus recombinants codant pour le transporteur specifique de l'iode (nis) |
-
1999
- 1999-06-11 FR FR9907449A patent/FR2794771B1/fr not_active Expired - Fee Related
-
2000
- 2000-06-08 HU HU0201455A patent/HUP0201455A3/hu unknown
- 2000-06-08 AU AU55407/00A patent/AU782934B2/en not_active Ceased
- 2000-06-08 CA CA002376735A patent/CA2376735A1/fr not_active Abandoned
- 2000-06-08 KR KR1020017015802A patent/KR100708949B1/ko not_active IP Right Cessation
- 2000-06-08 MX MXPA01012004A patent/MXPA01012004A/es unknown
- 2000-06-08 WO PCT/FR2000/001594 patent/WO2000076450A2/fr active IP Right Grant
- 2000-06-08 EP EP00940476A patent/EP1187919B1/fr not_active Expired - Lifetime
- 2000-06-08 IL IL14618200A patent/IL146182A0/xx unknown
- 2000-06-08 DE DE60037189T patent/DE60037189T2/de not_active Expired - Lifetime
- 2000-06-08 CN CNB008085900A patent/CN1259418C/zh not_active Expired - Fee Related
- 2000-06-08 JP JP2001502790A patent/JP2003501107A/ja active Pending
-
2009
- 2009-09-25 US US12/567,076 patent/US20100080775A1/en not_active Abandoned
-
2012
- 2012-07-02 US US13/540,421 patent/US8642028B2/en not_active Expired - Fee Related
- 2012-10-11 JP JP2012225794A patent/JP2013048626A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
KR20020028893A (ko) | 2002-04-17 |
AU5540700A (en) | 2001-01-02 |
WO2000076450A3 (fr) | 2001-06-28 |
JP2003501107A (ja) | 2003-01-14 |
FR2794771B1 (fr) | 2001-08-10 |
HUP0201455A2 (en) | 2002-08-28 |
EP1187919A2 (fr) | 2002-03-20 |
CN1408022A (zh) | 2003-04-02 |
AU782934B2 (en) | 2005-09-08 |
JP2013048626A (ja) | 2013-03-14 |
WO2000076450A2 (fr) | 2000-12-21 |
US20100080775A1 (en) | 2010-04-01 |
US20120269773A1 (en) | 2012-10-25 |
CA2376735A1 (fr) | 2000-12-21 |
US8642028B2 (en) | 2014-02-04 |
DE60037189D1 (de) | 2008-01-03 |
HUP0201455A3 (en) | 2004-12-28 |
CN1259418C (zh) | 2006-06-14 |
KR100708949B1 (ko) | 2007-04-18 |
FR2794771A1 (fr) | 2000-12-15 |
MXPA01012004A (es) | 2002-05-06 |
DE60037189T2 (de) | 2008-10-09 |
EP1187919B1 (fr) | 2007-11-21 |
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