IL146090A0 - A synthetic gene for expression of a retroviral protein with wild type activity in eukaryotic cells - Google Patents

A synthetic gene for expression of a retroviral protein with wild type activity in eukaryotic cells

Info

Publication number
IL146090A0
IL146090A0 IL14609000A IL14609000A IL146090A0 IL 146090 A0 IL146090 A0 IL 146090A0 IL 14609000 A IL14609000 A IL 14609000A IL 14609000 A IL14609000 A IL 14609000A IL 146090 A0 IL146090 A0 IL 146090A0
Authority
IL
Israel
Prior art keywords
expression
wild type
eukaryotic cells
synthetic gene
type activity
Prior art date
Application number
IL14609000A
Other languages
English (en)
Original Assignee
Leuven K U Res & Dev
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Leuven K U Res & Dev filed Critical Leuven K U Res & Dev
Publication of IL146090A0 publication Critical patent/IL146090A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16041—Use of virus, viral particle or viral elements as a vector
    • C12N2740/16043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16051—Methods of production or purification of viral material
    • C12N2740/16052—Methods of production or purification of viral material relating to complementing cells and packaging systems for producing virus or viral particles
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16111—Human Immunodeficiency Virus, HIV concerning HIV env
    • C12N2740/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2800/00—Nucleic acids vectors
    • C12N2800/10—Plasmid DNA
    • C12N2800/108—Plasmid DNA episomal vectors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2840/00—Vectors comprising a special translation-regulating system
    • C12N2840/20—Vectors comprising a special translation-regulating system translation of more than one cistron
    • C12N2840/203—Vectors comprising a special translation-regulating system translation of more than one cistron having an IRES

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
IL14609000A 1999-04-26 2000-04-26 A synthetic gene for expression of a retroviral protein with wild type activity in eukaryotic cells IL146090A0 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP99201306 1999-04-26
EP00200171 2000-01-18
PCT/EP2000/003765 WO2000065076A2 (fr) 1999-04-26 2000-04-26 Gene synthetique destine a l'expression d'une proteine retrovirale active dans les eucariotes

Publications (1)

Publication Number Publication Date
IL146090A0 true IL146090A0 (en) 2002-07-25

Family

ID=26071747

Family Applications (1)

Application Number Title Priority Date Filing Date
IL14609000A IL146090A0 (en) 1999-04-26 2000-04-26 A synthetic gene for expression of a retroviral protein with wild type activity in eukaryotic cells

Country Status (11)

Country Link
EP (1) EP1183381A2 (fr)
JP (1) JP2002542791A (fr)
AU (1) AU778106B2 (fr)
BR (1) BR0010077A (fr)
CA (1) CA2369058A1 (fr)
HU (1) HUP0201019A2 (fr)
IL (1) IL146090A0 (fr)
NO (1) NO20015168L (fr)
PL (1) PL351988A1 (fr)
RU (1) RU2001131728A (fr)
WO (1) WO2000065076A2 (fr)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9803351D0 (en) 1998-02-17 1998-04-15 Oxford Biomedica Ltd Anti-viral vectors
AU2487300A (en) 1998-12-31 2000-07-31 Chiron Corporation Polynucleotides encoding antigenic hiv type c polypeptides, polypeptides and uses thereof
US6656706B2 (en) 1999-12-23 2003-12-02 The United States Of America As Represented By The Department Of Health And Human Services Molecular clones with mutated HIV gag/pol, SIV gag and SIV env genes
WO2001046408A2 (fr) * 1999-12-23 2001-06-28 The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Clones moleculaires avec genes mutes vih gag/pol, vis gag et vis env
AUPQ580300A0 (en) * 2000-02-23 2000-03-16 National Cancer Centre Of Singapore Pte Ltd Genetic analysis
GB0009760D0 (en) * 2000-04-19 2000-06-07 Oxford Biomedica Ltd Method
WO2003004620A2 (fr) 2001-07-05 2003-01-16 Chiron, Corporation Polynucleotides codant des polypeptides de type c du vih antigeniques, polypeptides et leurs utilisations
US6835568B2 (en) 2001-10-30 2004-12-28 Virxsys Corporation Regulated nucleic acid expression system
JP4385135B2 (ja) * 2003-05-06 2009-12-16 独立行政法人産業技術総合研究所 マルチ遺伝子転写活性測定システム
EP1934246B8 (fr) * 2005-10-07 2012-02-08 Istituto di Ricerche di Biologia Molecolare P. Angeletti S.R.L. Vaccin de metalloproteinase 11 matricielle
JP6824594B2 (ja) 2014-09-11 2021-02-03 Jnc株式会社 合成遺伝子の設計方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5468629A (en) * 1993-04-13 1995-11-21 Calhoun; Cornelia Method of promoting in vitro homologous recombination transfection in mammalian cells using the RecA protein
US5434065A (en) * 1993-05-06 1995-07-18 President And Fellows Of Harvard College In vivo selection of microbial virulence genes
US5811270A (en) * 1994-05-20 1998-09-22 Grandgenett; Duane P. In vitro method for concerted integration of donor DNA molecules using retroviral integrase proteins
US6200811B1 (en) * 1996-04-02 2001-03-13 The Regents Of The University Of California Cell transformation vector comprising an HIV-2 packaging site nucleic acid and an HIV-1 GAG protein
US6114148C1 (en) * 1996-09-20 2012-05-01 Gen Hospital Corp High level expression of proteins
CA2280195A1 (fr) * 1997-02-07 1998-08-13 Merck & Co., Inc. Genes synthetiques du gag hiv
AU2487300A (en) * 1998-12-31 2000-07-31 Chiron Corporation Polynucleotides encoding antigenic hiv type c polypeptides, polypeptides and uses thereof
AU2221600A (en) * 1998-12-31 2000-07-31 Chiron Corporation Improved expression of hiv polypeptides and production of virus-like particles

Also Published As

Publication number Publication date
BR0010077A (pt) 2002-01-15
AU778106B2 (en) 2004-11-18
RU2001131728A (ru) 2004-02-20
WO2000065076A2 (fr) 2000-11-02
NO20015168D0 (no) 2001-10-23
AU4557900A (en) 2000-11-10
HUP0201019A2 (en) 2002-08-28
NO20015168L (no) 2001-12-14
CA2369058A1 (fr) 2000-11-02
WO2000065076A3 (fr) 2001-12-13
EP1183381A2 (fr) 2002-03-06
JP2002542791A (ja) 2002-12-17
PL351988A1 (en) 2003-07-14

Similar Documents

Publication Publication Date Title
PT1192244E (pt) Células vegetais e plantas geneticamente modificadas possuindo uma maior actividade de uma proteína amilosucrase e de uma enzima ramificadora
AU5734998A (en) Embryonic stem cell serum replacement
AU6208098A (en) Protein with phospholipase activity
AU3419200A (en) Polypeptides having alkaline alpha-amylase activity and nucleic acids encoding same
AU2576699A (en) Erythropoietin with altered biological activity
AU1201600A (en) Controlling gene expression in living cells
IL146090A0 (en) A synthetic gene for expression of a retroviral protein with wild type activity in eukaryotic cells
AU2578899A (en) Multimeric erythropoietin with altered biological activity
AU6056501A (en) Measurements of enzymatic activity in a single, individual cell in population
AU2878600A (en) Polynucleotide encoding a polypeptide having heparanase activity and expression of same in genetically modified cells
ZA9810915B (en) Optimization of cells for endogenous gene activation.
PL337942A1 (en) Isolated genes of dendricall cell membranic proteins
IL139739A0 (en) Polypeptides with beta-secretase type activity
EP0973867A4 (fr) Milieux de culture cellulaire pour elaboration de proteines amelioree
AU3584993A (en) Methods and compositions for neutralizing intracellular nucleic acid-binding protein biological activity in a cell, including methods and compositions useful to regulate gene function
GB9714936D0 (en) Cell culture products
AU2656800A (en) Chemokine-like factors having cell chemokinesis function and proliferation-stimulating activity
AU7494200A (en) Proteins associated with cell differentiation
AU3366099A (en) Drm, a secreted protein with cell growth inhibiting activity, and related methods and compositions
GB2314332B (en) Gene expression in mammalian cells
AU7106398A (en) Automated external defibrillator battery memory, dual cell, and removable configurations
AU3054899A (en) Cell line not expressing beta-secretase activity
GB2331750B (en) Gene for a cell wall lytic enzyme
HU230003B1 (en) Bisindolylmaleimides with inhibitory activity on cell proliferation
AU8999298A (en) Protein having activity of activiting nerve cell functions