IL143379A - Oligonucleotide against human ache isoform r and its uses - Google Patents
Oligonucleotide against human ache isoform r and its usesInfo
- Publication number
- IL143379A IL143379A IL143379A IL14337901A IL143379A IL 143379 A IL143379 A IL 143379A IL 143379 A IL143379 A IL 143379A IL 14337901 A IL14337901 A IL 14337901A IL 143379 A IL143379 A IL 143379A
- Authority
- IL
- Israel
- Prior art keywords
- ache
- antisense
- antisense oligodeoxynucleotide
- nuclease resistant
- mrna
- Prior art date
Links
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- C12N15/1137—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against enzymes
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Priority Applications (11)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IL143379A IL143379A (en) | 2001-05-24 | 2001-05-24 | Oligonucleotide against human ache isoform r and its uses |
| AU2002256873A AU2002256873B2 (en) | 2001-05-24 | 2002-05-23 | Antisense oligonucleotide against human acetylcholinesterase (AChE) and uses thereof |
| JP2003509100A JP4316373B2 (ja) | 2001-05-24 | 2002-05-23 | ヒトのアセチルコリンエステラーゼ（ａｃｈｅ）に対するアンチセンスオリゴヌクレオチド及びその使用 |
| PCT/IL2002/000411 WO2003002739A1 (en) | 2001-05-24 | 2002-05-23 | Antisense oligonucleotide against human acetylcholinesterase (ache) and uses thereof |
| ES02726406T ES2397302T3 (es) | 2001-05-24 | 2002-05-23 | Oligonucleótido antisentido contra la isoforma R de la acetilcolinesterasa humana (ACHE-R) y sus usos |
| CA2458806A CA2458806C (en) | 2001-05-24 | 2002-05-23 | Antisense oligonucleotide against human ache and uses thereof |
| NZ529549A NZ529549A (en) | 2001-05-24 | 2002-05-23 | Antisense oligonucleotide against human acetylcholinesterase (ACHE) capable of crossing the blood brain barrier |
| EP02726406A EP1390493B1 (en) | 2001-05-24 | 2002-05-23 | Antisense oligonucleotide against human acetylcholinesterase isoform r (ache-r) and uses thereof |
| US10/402,016 US7074915B2 (en) | 2001-05-24 | 2003-03-27 | Antisense oligonucleotide against human acetylcholinesterase (AChE) and uses thereof |
| US11/346,145 US7456154B2 (en) | 2001-05-24 | 2006-02-01 | Antisense oligonucleotide against human acetylcholinesterase (AChE) and uses thereof |
| US12/287,274 US20090281165A1 (en) | 2001-05-24 | 2008-10-07 | Antisense oligonucleotide against human acetylcholinesterase (AChE) and uses thereof |
Applications Claiming Priority (1)
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|---|---|---|---|
| IL143379A IL143379A (en) | 2001-05-24 | 2001-05-24 | Oligonucleotide against human ache isoform r and its uses |
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| IL143379A0 IL143379A0 (en) | 2002-04-21 |
| IL143379A true IL143379A (en) | 2013-11-28 |
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| IL143379A IL143379A (en) | 2001-05-24 | 2001-05-24 | Oligonucleotide against human ache isoform r and its uses |
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| CA (1) | CA2458806C (enExample) |
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| NZ (1) | NZ529549A (enExample) |
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| IL143379A (en) * | 2001-05-24 | 2013-11-28 | Yissum Res Dev Co | Oligonucleotide against human ache isoform r and its uses |
| AU2003225410A1 (en) | 2003-03-21 | 2004-10-11 | Academisch Ziekenhuis Leiden | Modulation of exon recognition in pre-mrna by interfering with the secondary rna structure |
| US7766902B2 (en) | 2003-08-13 | 2010-08-03 | Wisconsin Alumni Research Foundation | Microfluidic device for drug delivery |
| IL158600A (en) | 2003-10-26 | 2015-07-30 | Hermona Soreq | Dioxysoligonucleotide Antisense Against Acetylcholinesterase as an Anti-Inflammatory Agent |
| GB2441581B (en) * | 2005-06-24 | 2011-01-19 | Roderic M K Dale | Compositions and methods for the treatment of muscle wasting |
| CN103301475B (zh) | 2005-12-28 | 2016-08-03 | 斯克里普斯研究所 | 药物组合物和表达载体以及调节基因表达的方法和核酸分子的应用 |
| GB0605337D0 (en) | 2006-03-17 | 2006-04-26 | Genomica Sau | Treatment of CNS conditions |
| WO2007116395A2 (en) * | 2006-04-10 | 2007-10-18 | Ester Neurosciences Ltd. | Antisense oligonucleotides against acetylcholinesterase for treating inflammatory diseases |
| WO2007123391A1 (en) | 2006-04-20 | 2007-11-01 | Academisch Ziekenhuis Leiden | Therapeutic intervention in a genetic disease in an individual by modifying expression of an aberrantly expressed gene. |
| EP1857548A1 (en) | 2006-05-19 | 2007-11-21 | Academisch Ziekenhuis Leiden | Means and method for inducing exon-skipping |
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| IL101600A (en) * | 1992-04-15 | 2000-02-29 | Yissum Res Dev Co | Synthetic partially phosphorothioated antisense oligodeoxynucleotides and pharmaceutical compositions containing them |
| US6110742A (en) * | 1992-04-15 | 2000-08-29 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Synthetic antisense oligodeoxynucleotides targeted to AChE |
| WO1994021294A1 (en) | 1993-03-19 | 1994-09-29 | Bigner Darell D | Method of treating tumors with antibodies |
| US5455044A (en) * | 1993-05-14 | 1995-10-03 | Depotech Corporation | Method for treating neurological disorders |
| DE69737296T2 (de) | 1996-12-12 | 2007-11-08 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Synthetische antisense oligodeoxynukleotide und diese enthaltende pharmazeutische zusammensetzungen |
| IL132972A0 (en) * | 1999-11-16 | 2001-03-19 | Yissum Res Dev Co | Pharmaceutical compositions comprising acetylcholinesterase antisense deoxynucleotides for the treatment of muscular and neuromuscular disorders |
| IL143379A (en) * | 2001-05-24 | 2013-11-28 | Yissum Res Dev Co | Oligonucleotide against human ache isoform r and its uses |
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| US7456154B2 (en) | 2008-11-25 |
| CA2458806A1 (en) | 2003-01-09 |
| CA2458806C (en) | 2012-10-09 |
| US20030216344A1 (en) | 2003-11-20 |
| NZ529549A (en) | 2008-07-31 |
| AU2002256873B2 (en) | 2007-07-05 |
| EP1390493B1 (en) | 2012-11-07 |
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