IL143085A0 - Human brain endothelial cells and growth medium and method for expansion of primitive cd34+cd38 - bone marrow stem cells - Google Patents

Human brain endothelial cells and growth medium and method for expansion of primitive cd34+cd38 - bone marrow stem cells

Info

Publication number
IL143085A0
IL143085A0 IL14308599A IL14308599A IL143085A0 IL 143085 A0 IL143085 A0 IL 143085A0 IL 14308599 A IL14308599 A IL 14308599A IL 14308599 A IL14308599 A IL 14308599A IL 143085 A0 IL143085 A0 IL 143085A0
Authority
IL
Israel
Prior art keywords
primitive
expansion
bone marrow
growth medium
human brain
Prior art date
Application number
IL14308599A
Other languages
English (en)
Original Assignee
Naval Medical Res Ct
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Naval Medical Res Ct filed Critical Naval Medical Res Ct
Publication of IL143085A0 publication Critical patent/IL143085A0/xx

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0647—Haematopoietic stem cells; Uncommitted or multipotent progenitors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K2035/124—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells the cells being hematopoietic, bone marrow derived or blood cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/125—Stem cell factor [SCF], c-kit ligand [KL]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/20—Cytokines; Chemokines
    • C12N2501/22—Colony stimulating factors (G-CSF, GM-CSF)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/20—Cytokines; Chemokines
    • C12N2501/23—Interleukins [IL]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/20—Cytokines; Chemokines
    • C12N2501/26—Flt-3 ligand (CD135L, flk-2 ligand)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2502/00—Coculture with; Conditioned medium produced by
    • C12N2502/28—Vascular endothelial cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Rheumatology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
IL14308599A 1998-12-04 1999-12-03 Human brain endothelial cells and growth medium and method for expansion of primitive cd34+cd38 - bone marrow stem cells IL143085A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11204298P 1998-12-04 1998-12-04
PCT/US1999/028939 WO2000036090A2 (en) 1998-12-04 1999-12-03 Human brain endothelial cells and growth medium and method for expansion of primitive cd34+cd38- bone marrow stem cells

Publications (1)

Publication Number Publication Date
IL143085A0 true IL143085A0 (en) 2002-04-21

Family

ID=22341823

Family Applications (3)

Application Number Title Priority Date Filing Date
IL14308599A IL143085A0 (en) 1998-12-04 1999-12-03 Human brain endothelial cells and growth medium and method for expansion of primitive cd34+cd38 - bone marrow stem cells
IL143085A IL143085A (en) 1998-12-04 2001-05-10 Human brain endothelial cells and tumor medium for expansion of brain-bone cells - CD34 + CD38 primitive
IL175471A IL175471A0 (en) 1998-12-04 2006-05-07 Human brain endothelial cells and growth medium and method for expansion of primitive cd34+cd38 - bone marrow stem cells

Family Applications After (2)

Application Number Title Priority Date Filing Date
IL143085A IL143085A (en) 1998-12-04 2001-05-10 Human brain endothelial cells and tumor medium for expansion of brain-bone cells - CD34 + CD38 primitive
IL175471A IL175471A0 (en) 1998-12-04 2006-05-07 Human brain endothelial cells and growth medium and method for expansion of primitive cd34+cd38 - bone marrow stem cells

Country Status (11)

Country Link
US (2) US6642049B1 (ja)
EP (1) EP1135465A2 (ja)
JP (1) JP2002532087A (ja)
KR (1) KR20020013480A (ja)
AU (1) AU778504B2 (ja)
CA (1) CA2353561A1 (ja)
IL (3) IL143085A0 (ja)
MX (1) MXPA01005564A (ja)
NZ (1) NZ511685A (ja)
WO (1) WO2000036090A2 (ja)
ZA (1) ZA200104175B (ja)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040235160A1 (en) * 2001-08-07 2004-11-25 Mitsuo Nishikawa Process for preparing hematopoietic stem cells
US20040151700A1 (en) * 2001-10-30 2004-08-05 Harlan David M. Ex-vivo rescue of transplantable hematopoietic stem cells following myeloablative injury
US7695723B2 (en) * 2002-12-31 2010-04-13 Sygnis Bioscience Gmbh & Co. Kg Methods of treating neurological conditions with hematopoietic growth factors
AU2004227205B2 (en) * 2003-04-08 2010-06-10 Yeda Research And Development Co. Ltd Stem cells having increased sensitivity to a chemoattractant and methods of generating and using same
EP1713903A2 (en) 2004-02-09 2006-10-25 Indiana University Research and Technology Corporation Isolation, expansion and use of clonogenic endothelial progenitor cells
KR100950195B1 (ko) * 2009-03-20 2010-03-29 서울대학교산학협력단 Ｚｎｆ281을 발현하는 제대혈 유래 만능 줄기세포의 분리방법
WO2012048275A2 (en) 2010-10-08 2012-04-12 Caridianbct, Inc. Configurable methods and systems of growing and harvesting cells in a hollow fiber bioreactor system
RU2496871C1 (ru) * 2012-08-09 2013-10-27 Сергей Владимирович Осутин Способ выделения стволовых клеток из костного мозга для внутрисосудистого введения
CN106062201B (zh) 2013-10-24 2020-11-06 圣拉法埃莱医院有限公司 方法
EP3068867B1 (en) 2013-11-16 2018-04-18 Terumo BCT, Inc. Expanding cells in a bioreactor
EP3122866B1 (en) 2014-03-25 2019-11-20 Terumo BCT, Inc. Passive replacement of media
CN106715676A (zh) 2014-09-26 2017-05-24 泰尔茂比司特公司 按计划供养
WO2016054591A1 (en) 2014-10-03 2016-04-07 Cedars-Sinai Medical Center Cardiosphere-derived cells and exosomes secreted by such cells in the treatment of muscular dystrophy
WO2017004592A1 (en) 2015-07-02 2017-01-05 Terumo Bct, Inc. Cell growth with mechanical stimuli
EP3464565A4 (en) 2016-05-25 2020-01-01 Terumo BCT, Inc. CELL EXPANSION
US11104874B2 (en) 2016-06-07 2021-08-31 Terumo Bct, Inc. Coating a bioreactor
US11685883B2 (en) 2016-06-07 2023-06-27 Terumo Bct, Inc. Methods and systems for coating a cell growth surface
US11624046B2 (en) 2017-03-31 2023-04-11 Terumo Bct, Inc. Cell expansion
CN117247899A (zh) 2017-03-31 2023-12-19 泰尔茂比司特公司 细胞扩增
US11697799B2 (en) * 2019-04-15 2023-07-11 Ossium Health, Inc. System and method for extraction and cryopreservation of bone marrow

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU4402193A (en) * 1992-06-08 1994-01-04 Becton Dickinson & Company Human primitive stem cells
US5599703A (en) * 1993-10-28 1997-02-04 The United States Of America As Represented By The Secretary Of The Navy In vitro amplification/expansion of CD34+ stem and progenitor cells
US5827742A (en) * 1994-09-01 1998-10-27 Beth Israel Deaconess Medical Center, Inc. Method of selecting pluripotent hematopioetic progenitor cells
US5969105A (en) * 1996-10-25 1999-10-19 Feng; Yiqing Stem cell factor receptor agonists
ES2178102T3 (es) * 1997-07-16 2002-12-16 Isotis Nv Dispositivo para la generacion de tejido oseo, que comprende un termoplastico de copoliester biodegradable y celulas cultivadas.

Also Published As

Publication number Publication date
IL175471A0 (en) 2006-09-05
CA2353561A1 (en) 2000-06-22
WO2000036090A3 (en) 2000-11-23
US20110091426A1 (en) 2011-04-21
WO2000036090A2 (en) 2000-06-22
MXPA01005564A (es) 2003-07-14
AU2044000A (en) 2000-07-03
KR20020013480A (ko) 2002-02-20
IL143085A (en) 2006-08-20
EP1135465A2 (en) 2001-09-26
AU778504B2 (en) 2004-12-09
JP2002532087A (ja) 2002-10-02
US6642049B1 (en) 2003-11-04
NZ511685A (en) 2003-12-19
ZA200104175B (en) 2002-03-13

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