IL141627A0 - Activation and protection of t-cells (cd4+and cd8+) using an h2 receptor agonist and other t-cell activating agents - Google Patents
Activation and protection of t-cells (cd4+and cd8+) using an h2 receptor agonist and other t-cell activating agentsInfo
- Publication number
- IL141627A0 IL141627A0 IL14162799A IL14162799A IL141627A0 IL 141627 A0 IL141627 A0 IL 141627A0 IL 14162799 A IL14162799 A IL 14162799A IL 14162799 A IL14162799 A IL 14162799A IL 141627 A0 IL141627 A0 IL 141627A0
- Authority
- IL
- Israel
- Prior art keywords
- activation
- cells
- protection
- receptor agonist
- cell activating
- Prior art date
Links
- 210000001744 T-lymphocyte Anatomy 0.000 title 1
- 230000003213 activating effect Effects 0.000 title 1
- 230000004913 activation Effects 0.000 title 1
- 239000003795 chemical substances by application Substances 0.000 title 1
- 239000003386 histamine H2 receptor agonist Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/20—Interleukins [IL]
- A61K38/2013—IL-2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/21—Interferons [IFN]
- A61K38/212—IFN-alpha
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K2035/124—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells the cells being hematopoietic, bone marrow derived or blood cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/515—Animal cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Mycology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Microbiology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Virology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US13928198A | 1998-08-24 | 1998-08-24 | |
PCT/US1999/019211 WO2000010600A2 (fr) | 1998-08-24 | 1999-08-24 | Activation et protection de cellules t (cd4?+ et cd8+¿) a l'aide d'un agoniste du recepteur h¿2? et d'autres agents activant les cellules t |
Publications (1)
Publication Number | Publication Date |
---|---|
IL141627A0 true IL141627A0 (en) | 2002-03-10 |
Family
ID=22485908
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL14162799A IL141627A0 (en) | 1998-08-24 | 1999-08-24 | Activation and protection of t-cells (cd4+and cd8+) using an h2 receptor agonist and other t-cell activating agents |
Country Status (11)
Country | Link |
---|---|
US (1) | US20030039628A1 (fr) |
EP (1) | EP1107784A2 (fr) |
JP (1) | JP2002523378A (fr) |
KR (1) | KR20010072957A (fr) |
CN (1) | CN1217698C (fr) |
AU (1) | AU765625C (fr) |
CA (1) | CA2341742A1 (fr) |
IL (1) | IL141627A0 (fr) |
TW (1) | TW576745B (fr) |
WO (1) | WO2000010600A2 (fr) |
ZA (1) | ZA200101787B (fr) |
Families Citing this family (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6242473B1 (en) * | 1999-01-08 | 2001-06-05 | Maxim Pharmaceuticals, Inc. | Treatment and prevention of reactive oxygen metabolite-mediated cellular damage |
JP2001247459A (ja) | 2000-03-03 | 2001-09-11 | Oakland Uniservices Ltd | 癌の組み合わせ療法 |
AU2001282717A1 (en) | 2000-07-28 | 2002-02-13 | Cancer Research Technology Limited | Cancer treatment by combination therapy |
US20020094323A1 (en) | 2000-10-12 | 2002-07-18 | Kristoffer Hellstrand | Methods and compositions for promoting the maturation of monocytes |
GB0121285D0 (en) | 2001-09-03 | 2001-10-24 | Cancer Res Ventures Ltd | Anti-cancer combinations |
CN1608204A (zh) * | 2001-12-21 | 2005-04-20 | 东弗吉尼亚医学院 | 分析药物效果的方法 |
GB2386836B (en) | 2002-03-22 | 2006-07-26 | Cancer Res Ventures Ltd | Anti-cancer combinations |
GB2394658A (en) | 2002-11-01 | 2004-05-05 | Cancer Rec Tech Ltd | Oral anti-cancer composition |
EP1603567A4 (fr) * | 2003-02-28 | 2006-10-18 | Inotek Pharmaceuticals Corp | Derives de benzamide tetracyclique et leurs procedes d'utilisation |
WO2005023293A1 (fr) * | 2003-09-09 | 2005-03-17 | Pohang University Of Science And Technology | Composition de vaccin comprenant un adjuvant d'il-12 encapsule dans une microsphere a liberation controlee |
CA2557547A1 (fr) * | 2004-02-26 | 2005-09-09 | Inotek Pharmaceuticals Corporation | Derives d'isoquinoline et methodes d'utilisation |
EP1722796A4 (fr) * | 2004-02-26 | 2008-01-23 | Inotek Pharmaceuticals Corp | Derives de lactame tetracyclique et utilisations |
CA2571001A1 (fr) * | 2004-06-16 | 2006-01-26 | Inotek Pharmaceuticals Corporation | Methodes de traitement ou de prevention de la dysfonction erectile ou de l'incontinence urinaire |
US20060079510A1 (en) * | 2004-09-30 | 2006-04-13 | Kristoffer Hellstrand | Use of PARP-1 inhibitors for protecting tumorcidal lymphocytes from apoptosis |
EP1850848A4 (fr) * | 2005-02-25 | 2008-02-20 | Inotek Pharmaceuticals Corp | Composes tetracycliques de sulfonamide et methodes d'utilisation desdits composes |
JP2008531562A (ja) * | 2005-02-25 | 2008-08-14 | イノテック ファーマシューティカルズ コーポレイション | 四環アミノ化合物および四環カルボキサミド化合物およびこれらの使用法 |
MX2007010335A (es) * | 2005-02-25 | 2007-11-06 | Inotek Pharmaceuticals Corp | Compuestos de isoquinolina y metodos de uso de los mismos. |
KR100735081B1 (ko) * | 2005-04-21 | 2007-07-06 | 고려대학교 산학협력단 | Cd4 t 세포 활성화 방법 |
KR100735083B1 (ko) * | 2005-04-21 | 2007-07-06 | 고려대학교 산학협력단 | Cd8 t 세포 활성화 방법 |
EP1937268A4 (fr) * | 2005-08-24 | 2009-07-22 | Inotek Pharmaceuticals Corp | Analogues d'indenoisoquinolinone et leurs procedes d'utilisation |
FR2903311B1 (fr) * | 2006-07-10 | 2012-06-15 | Centre Nat Rech Scient | Utilisation de ligands du recepteur h4 de l'histamine pour proteger les progeniteurs hematopoietiques contre la toxicite hematologique des agents chimiotherapeutiques |
JP2010520220A (ja) * | 2007-02-28 | 2010-06-10 | イノテック ファーマシューティカルズ コーポレイション | インデノイソキノリノン類似体およびその使用方法 |
RU2499043C1 (ru) * | 2012-09-26 | 2013-11-20 | Федеральное государственное унитарное предприятие "Государственный научно-исследовательский институт особо чистых биопрепаратов" Федерального медико-биологического агентства | Стимулятор пролиферации регуляторных т-лимфоцитов и способ их стимуляции |
CL2013001774A1 (es) * | 2013-06-18 | 2014-08-01 | Univ Santiago Chile | Formulacion con actividad inmunoestimulante/adyuvante que comprende alpinona , dimetil sulfóxido y suero fisiológico; uso de dicha formulación para preparar vacunas para vertebrados. |
US20160256388A1 (en) * | 2015-03-05 | 2016-09-08 | Uri Galili | Compositions and methods for treatment of respiratory tract infections |
CN115894595B (zh) * | 2021-09-30 | 2024-04-30 | 山东新时代药业有限公司 | 一种10,19-开环环阿屯烷三萜i及其制备方法和应用 |
CN115894601A (zh) * | 2021-09-30 | 2023-04-04 | 山东新时代药业有限公司 | 一种10,19-开环环阿屯烷三萜ii及其制备方法和应用 |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1993025240A2 (fr) * | 1992-06-09 | 1993-12-23 | Neorx Corporation | Procedes et composes de preciblage |
US5508031A (en) * | 1986-11-21 | 1996-04-16 | Cetus Oncology Corporation | Method for treating biological damage using a free-radial scavenger and interleukin-2 |
CA2066728C (fr) * | 1989-09-19 | 2001-12-25 | Jan K. Hellstrand | Preparation anti-tumorale composee d'interleukine-2 et d'histamine, leurs analogues ou agonistes des recepteurs h2 |
SE513429C2 (sv) * | 1992-06-03 | 2000-09-11 | Syntello Inc | Preparat för aktivering av naturliga mördarceller, vilket preparat innehåller interferon alfa och biogena aminer |
JPH10504304A (ja) * | 1994-08-08 | 1998-04-28 | マキシム ファーマシューティカルズ,インコーポレイテッド | ナチュラルキラー細胞活性化物質と過酸化水素スカベンジャーまたは過酸化水素阻害物質とを用いるナチュラルキラー細胞の活性増強 |
GB9416657D0 (en) * | 1994-08-17 | 1994-10-12 | Biocine Spa | T cell activation |
WO1997030174A1 (fr) * | 1996-02-20 | 1997-08-21 | Sloan-Kettering Institute For Cancer Research | Combinaison d'inhibiteurs de la proteine kinase c et agents therapeutiques pour traiter des cancers |
ATE437366T1 (de) * | 1998-05-11 | 2009-08-15 | Miltenyi Biotec Gmbh | Verfahren zur direkten auswahl von antigen- spezifischen t-zellen |
-
1999
- 1999-08-24 WO PCT/US1999/019211 patent/WO2000010600A2/fr not_active Application Discontinuation
- 1999-08-24 CN CN998125385A patent/CN1217698C/zh not_active Expired - Fee Related
- 1999-08-24 IL IL14162799A patent/IL141627A0/xx unknown
- 1999-08-24 AU AU56870/99A patent/AU765625C/en not_active Ceased
- 1999-08-24 JP JP2000565920A patent/JP2002523378A/ja active Pending
- 1999-08-24 EP EP99943853A patent/EP1107784A2/fr not_active Withdrawn
- 1999-08-24 KR KR1020017002395A patent/KR20010072957A/ko active IP Right Grant
- 1999-08-24 CA CA002341742A patent/CA2341742A1/fr not_active Abandoned
- 1999-09-22 TW TW088114376A patent/TW576745B/zh not_active IP Right Cessation
-
2001
- 2001-03-02 ZA ZA200101787A patent/ZA200101787B/en unknown
-
2002
- 2002-10-03 US US10/265,521 patent/US20030039628A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
WO2000010600A3 (fr) | 2000-06-15 |
CA2341742A1 (fr) | 2000-03-02 |
WO2000010600A2 (fr) | 2000-03-02 |
KR20010072957A (ko) | 2001-07-31 |
EP1107784A2 (fr) | 2001-06-20 |
ZA200101787B (en) | 2001-09-27 |
WO2000010600A9 (fr) | 2001-11-22 |
TW576745B (en) | 2004-02-21 |
CN1217698C (zh) | 2005-09-07 |
AU5687099A (en) | 2000-03-14 |
CN1324245A (zh) | 2001-11-28 |
JP2002523378A (ja) | 2002-07-30 |
US20030039628A1 (en) | 2003-02-27 |
AU765625C (en) | 2004-11-18 |
AU765625B2 (en) | 2003-09-25 |
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