IL137329A0 - Vla-4 antagonists - Google Patents
Vla-4 antagonistsInfo
- Publication number
- IL137329A0 IL137329A0 IL13732999A IL13732999A IL137329A0 IL 137329 A0 IL137329 A0 IL 137329A0 IL 13732999 A IL13732999 A IL 13732999A IL 13732999 A IL13732999 A IL 13732999A IL 137329 A0 IL137329 A0 IL 137329A0
- Authority
- IL
- Israel
- Prior art keywords
- vla
- antagonists
- Prior art date
Links
- 239000005557 antagonist Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
- C07C237/22—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton having nitrogen atoms of amino groups bound to the carbon skeleton of the acid part, further acylated
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C275/28—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
- C07C275/42—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by carboxyl groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/07—Optical isomers
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Immunology (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Transplantation (AREA)
- Pain & Pain Management (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US1233698A | 1998-01-23 | 1998-01-23 | |
| US11072398P | 1998-12-03 | 1998-12-03 | |
| PCT/EP1999/000384 WO1999037605A1 (en) | 1998-01-23 | 1999-01-21 | Vla-4 antagonists |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL137329A0 true IL137329A0 (en) | 2001-07-24 |
Family
ID=26683440
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL13732999A IL137329A0 (en) | 1998-01-23 | 1999-01-21 | Vla-4 antagonists |
Country Status (13)
| Country | Link |
|---|---|
| EP (1) | EP1049665A1 (https=) |
| JP (1) | JP4564654B2 (https=) |
| KR (1) | KR20010034317A (https=) |
| CN (1) | CN1294576A (https=) |
| AU (1) | AU746174B2 (https=) |
| BR (1) | BR9907733A (https=) |
| CA (1) | CA2318639A1 (https=) |
| EE (1) | EE200000428A (https=) |
| HU (1) | HUP0100336A3 (https=) |
| ID (1) | ID26665A (https=) |
| IL (1) | IL137329A0 (https=) |
| NO (1) | NO20003694L (https=) |
| WO (1) | WO1999037605A1 (https=) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2623900A (en) * | 1999-01-22 | 2000-08-07 | American Home Products Corporation | Compounds which inhibit leukocyte adhesion mediated by vla-4 |
| ATE455106T1 (de) | 1999-01-22 | 2010-01-15 | Elan Pharm Inc | Acyl derivate zur behandlung von krankheiten die in zusammenhang mit vla-4 stehen |
| US6436904B1 (en) | 1999-01-25 | 2002-08-20 | Elan Pharmaceuticals, Inc. | Compounds which inhibit leukocyte adhesion mediated by VLA-4 |
| JP2002538135A (ja) | 1999-03-01 | 2002-11-12 | エラン ファーマシューティカルズ，インコーポレイテッド | α４β７レセプターアンタゴニストとして有用なα−アミノ酢酸誘導体 |
| AU3006401A (en) * | 1999-12-07 | 2001-06-18 | Novartis Ag | Vla-4 integrin antagonists |
| YU41202A (sh) * | 1999-12-28 | 2005-03-15 | Pfizer Products Inc. | Ne-peptidni inhibitori vezivanja za ćeliju zavisnog od vla-4 korisni pri tretiranju inflamatornih, autoimunih i respiratornih bolesti |
| DE10019755A1 (de) * | 2000-04-20 | 2001-11-08 | Bayer Ag | Neue Aminoaryl/cycloalkylcarbonsäuren als Integrinantagonisten |
| GB2369357A (en) * | 2000-10-09 | 2002-05-29 | Bayer Ag | Aliphatic, cyclic amino carboxylic acids as integrin antagonists |
| GB2367816A (en) * | 2000-10-09 | 2002-04-17 | Bayer Ag | Urea- and thiourea-containing derivatives of beta-amino acids |
| GB2377933A (en) | 2001-07-06 | 2003-01-29 | Bayer Ag | Succinic acid derivatives useful as integrin antagonists |
| TW200307671A (en) | 2002-05-24 | 2003-12-16 | Elan Pharm Inc | Heteroaryl compounds which inhibit leukocyte adhesion mediated by α 4 integrins |
| TWI281470B (en) | 2002-05-24 | 2007-05-21 | Elan Pharm Inc | Heterocyclic compounds which inhibit leukocyte adhesion mediated by alpha4 integrins |
| TW200610754A (en) * | 2004-06-14 | 2006-04-01 | Daiichi Seiyaku Co | Vla-4 inhibitor |
| GB0523576D0 (en) * | 2005-11-18 | 2005-12-28 | Theradeas Ltd | Drug composition and its use in therapy |
| CA2643838A1 (en) | 2006-02-27 | 2007-09-07 | Elan Pharmaceuticals, Inc. | Pyrimidinyl sulfonamide compounds which inhibit leukocyte adhesion mediated by vla-4 |
| WO2008103378A2 (en) | 2007-02-20 | 2008-08-28 | Merrimack Pharmaceuticals, Inc. | Methods of treating multiple sclerosis by administration of alpha-fetoprotein in combination with an integrin antagonist |
| MX2010011145A (es) | 2008-04-11 | 2011-04-11 | Merrimack Pharmaceuticals Inc | Enlazadores de la albumina de suero humana y conjugados de la misma. |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6306840B1 (en) * | 1995-01-23 | 2001-10-23 | Biogen, Inc. | Cell adhesion inhibitors |
| IL136584A (en) * | 1997-12-23 | 2005-03-20 | Aventis Pharma Ltd | SUBSTITUTED beta-ALANINES, PHARMACEUTICAL COMPOSITIONS COMPRISING THEM AND USES THEREOF |
-
1999
- 1999-01-21 KR KR1020007008039A patent/KR20010034317A/ko not_active Withdrawn
- 1999-01-21 ID IDW20001404A patent/ID26665A/id unknown
- 1999-01-21 BR BR9907733-7A patent/BR9907733A/pt not_active IP Right Cessation
- 1999-01-21 HU HU0100336A patent/HUP0100336A3/hu unknown
- 1999-01-21 IL IL13732999A patent/IL137329A0/xx unknown
- 1999-01-21 EE EEP200000428A patent/EE200000428A/xx unknown
- 1999-01-21 CA CA002318639A patent/CA2318639A1/en not_active Abandoned
- 1999-01-21 WO PCT/EP1999/000384 patent/WO1999037605A1/en not_active Ceased
- 1999-01-21 EP EP99908811A patent/EP1049665A1/en not_active Withdrawn
- 1999-01-21 JP JP2000528529A patent/JP4564654B2/ja not_active Expired - Fee Related
- 1999-01-21 AU AU28292/99A patent/AU746174B2/en not_active Ceased
- 1999-01-21 CN CN99803780A patent/CN1294576A/zh active Pending
-
2000
- 2000-07-19 NO NO20003694A patent/NO20003694L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| KR20010034317A (ko) | 2001-04-25 |
| AU2829299A (en) | 1999-08-09 |
| WO1999037605A1 (en) | 1999-07-29 |
| AU746174B2 (en) | 2002-04-18 |
| ID26665A (id) | 2001-01-25 |
| CA2318639A1 (en) | 1999-07-29 |
| BR9907733A (pt) | 2000-10-17 |
| HUP0100336A3 (en) | 2002-11-28 |
| JP4564654B2 (ja) | 2010-10-20 |
| EE200000428A (et) | 2001-12-17 |
| CN1294576A (zh) | 2001-05-09 |
| NO20003694L (no) | 2000-09-20 |
| EP1049665A1 (en) | 2000-11-08 |
| JP2002501039A (ja) | 2002-01-15 |
| HUP0100336A2 (hu) | 2001-07-30 |
| NO20003694D0 (no) | 2000-07-19 |
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