IL137247A0 - Transfecting compositions sensitive to reducing conditions, pharmaceutical compositions containing them, and their applications - Google Patents
Transfecting compositions sensitive to reducing conditions, pharmaceutical compositions containing them, and their applicationsInfo
- Publication number
- IL137247A0 IL137247A0 IL13724799A IL13724799A IL137247A0 IL 137247 A0 IL137247 A0 IL 137247A0 IL 13724799 A IL13724799 A IL 13724799A IL 13724799 A IL13724799 A IL 13724799A IL 137247 A0 IL137247 A0 IL 137247A0
- Authority
- IL
- Israel
- Prior art keywords
- reducing conditions
- applications
- sensitive
- transfecting
- pharmaceutical compositions
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
- A61K47/6901—Conjugates being cells, cell fragments, viruses, ghosts, red blood cells or viral vectors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
- C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
- C07C323/60—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton with the carbon atom of at least one of the carboxyl groups bound to nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
- C07K5/06026—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atom, i.e. Gly or Ala
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9801065A FR2774394B1 (fr) | 1998-01-30 | 1998-01-30 | Composes transfectants sensibles aux conditions reductrices, compositions pharmaceutiques les contenant, et leurs applications |
US7702698P | 1998-03-06 | 1998-03-06 | |
PCT/FR1999/000162 WO1999038821A2 (fr) | 1998-01-30 | 1999-01-28 | Composes transfectants sensibles aux conditions reductrices, compositions pharmaceutiques les contenant, et leurs applications |
Publications (1)
Publication Number | Publication Date |
---|---|
IL137247A0 true IL137247A0 (en) | 2001-07-24 |
Family
ID=26234096
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL13724799A IL137247A0 (en) | 1998-01-30 | 1999-01-28 | Transfecting compositions sensitive to reducing conditions, pharmaceutical compositions containing them, and their applications |
Country Status (14)
Country | Link |
---|---|
US (1) | US6521252B1 (de) |
EP (1) | EP1049793B1 (de) |
JP (1) | JP2002501762A (de) |
KR (1) | KR20010081924A (de) |
CN (1) | CN1289371A (de) |
AT (1) | ATE306556T1 (de) |
AU (1) | AU759197B2 (de) |
BR (1) | BR9907269A (de) |
CA (1) | CA2318512C (de) |
DE (1) | DE69927669T2 (de) |
HU (1) | HUP0101393A3 (de) |
IL (1) | IL137247A0 (de) |
NO (1) | NO20003880L (de) |
WO (1) | WO1999038821A2 (de) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6169078B1 (en) * | 1998-05-12 | 2001-01-02 | University Of Florida | Materials and methods for the intracellular delivery of substances |
US6379698B1 (en) | 1999-04-06 | 2002-04-30 | Isis Pharmaceuticals, Inc. | Fusogenic lipids and vesicles |
AU2001294185B2 (en) * | 2000-10-04 | 2006-12-21 | Kyowa Hakko Kirin Co., Ltd. | Method of coating fine particles with lipid membrane |
KR20100065190A (ko) * | 2007-09-14 | 2010-06-15 | 닛토덴코 가부시키가이샤 | 약물 담체 |
FR2921369B1 (fr) * | 2007-09-25 | 2014-07-11 | Pf Medicament | Nouveau procede de preparation de derives (poly) aminoalkylaminoacetamide d'epipodophyllotoxine,utiles pour leurs applications en therapeutique comme agent anticancereux. |
GB0720486D0 (en) * | 2007-10-19 | 2007-11-28 | Univ Edinburgh | Cationic lipids |
JP6762094B2 (ja) * | 2013-02-28 | 2020-09-30 | タフツ ユニバーシティー | 薬剤のデリバリーのためのジスルフィド化合物 |
US11433128B2 (en) * | 2017-04-07 | 2022-09-06 | Tianxin Wang | Cell surface anchoring antigen conjugates to treat cancer |
WO2019160780A1 (en) * | 2018-02-16 | 2019-08-22 | Wang tian xin | Methods and agents to treat tumor cells and cancer |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2645866B1 (fr) | 1989-04-17 | 1991-07-05 | Centre Nat Rech Scient | Nouvelles lipopolyamines, leur preparation et leur emploi |
AU7759291A (en) | 1990-03-29 | 1991-10-21 | Gilead Sciences, Inc. | Oligonucleotide-transport agent disulfide conjugates |
US5283185A (en) * | 1991-08-28 | 1994-02-01 | University Of Tennessee Research Corporation | Method for delivering nucleic acids into cells |
US5837533A (en) * | 1994-09-28 | 1998-11-17 | American Home Products Corporation | Complexes comprising a nucleic acid bound to a cationic polyamine having an endosome disruption agent |
FR2727679B1 (fr) | 1994-12-05 | 1997-01-03 | Rhone Poulenc Rorer Sa | Nouveaux agents de transfection et leurs applications pharmaceutiques |
FR2730637B1 (fr) * | 1995-02-17 | 1997-03-28 | Rhone Poulenc Rorer Sa | Composition pharmaceutique contenant des acides nucleiques, et ses utilisations |
CA2222586A1 (en) | 1995-06-07 | 1996-12-19 | Gen-Probe Incorporated | Thiocationic lipids, pharmaceutical compositions and methods of use thereof |
FR2741066B1 (fr) * | 1995-11-14 | 1997-12-12 | Rhone Poulenc Rorer Sa | Nouveaux agents de transfection et leurs applications pharmaceutiques |
US5942634A (en) * | 1997-05-09 | 1999-08-24 | Genzyme Corporation | Cationic amphiphiles for cell transfections |
EP0945138A1 (de) | 1997-12-04 | 1999-09-29 | Université Louis Pasteur de Strasbourg | Partikeltransfektion |
US6169078B1 (en) | 1998-05-12 | 2001-01-02 | University Of Florida | Materials and methods for the intracellular delivery of substances |
-
1999
- 1999-01-28 DE DE69927669T patent/DE69927669T2/de not_active Expired - Lifetime
- 1999-01-28 IL IL13724799A patent/IL137247A0/xx unknown
- 1999-01-28 AT AT99901639T patent/ATE306556T1/de not_active IP Right Cessation
- 1999-01-28 CN CN99802464A patent/CN1289371A/zh active Pending
- 1999-01-28 WO PCT/FR1999/000162 patent/WO1999038821A2/fr not_active Application Discontinuation
- 1999-01-28 CA CA002318512A patent/CA2318512C/fr not_active Expired - Fee Related
- 1999-01-28 HU HU0101393A patent/HUP0101393A3/hu unknown
- 1999-01-28 JP JP2000530060A patent/JP2002501762A/ja active Pending
- 1999-01-28 KR KR1020007008257A patent/KR20010081924A/ko not_active Application Discontinuation
- 1999-01-28 EP EP99901639A patent/EP1049793B1/de not_active Expired - Lifetime
- 1999-01-28 BR BR9907269-6A patent/BR9907269A/pt not_active IP Right Cessation
-
2000
- 2000-07-04 AU AU43843/00A patent/AU759197B2/en not_active Ceased
- 2000-07-06 US US09/610,727 patent/US6521252B1/en not_active Expired - Fee Related
- 2000-07-28 NO NO20003880A patent/NO20003880L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
CN1289371A (zh) | 2001-03-28 |
DE69927669D1 (de) | 2006-02-23 |
AU759197B2 (en) | 2003-04-10 |
WO1999038821A2 (fr) | 1999-08-05 |
NO20003880D0 (no) | 2000-07-28 |
AU4384300A (en) | 2001-04-05 |
CA2318512C (fr) | 2009-10-13 |
JP2002501762A (ja) | 2002-01-22 |
EP1049793B1 (de) | 2005-10-12 |
DE69927669T2 (de) | 2006-07-20 |
WO1999038821A3 (fr) | 1999-09-23 |
CA2318512A1 (fr) | 1999-08-05 |
BR9907269A (pt) | 2001-04-03 |
EP1049793A2 (de) | 2000-11-08 |
NO20003880L (no) | 2000-07-28 |
KR20010081924A (ko) | 2001-08-29 |
HUP0101393A3 (en) | 2004-10-28 |
HUP0101393A1 (hu) | 2001-08-28 |
ATE306556T1 (de) | 2005-10-15 |
US6521252B1 (en) | 2003-02-18 |
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