IL137121A0 - Variable heavy chain and variable light chain regions of antibodies to human platelet glycoprotein ib alpha - Google Patents

Variable heavy chain and variable light chain regions of antibodies to human platelet glycoprotein ib alpha

Info

Publication number
IL137121A0
IL137121A0 IL13712199A IL13712199A IL137121A0 IL 137121 A0 IL137121 A0 IL 137121A0 IL 13712199 A IL13712199 A IL 13712199A IL 13712199 A IL13712199 A IL 13712199A IL 137121 A0 IL137121 A0 IL 137121A0
Authority
IL
Israel
Prior art keywords
heavy chain
light chain
alpha
antibody
variable
Prior art date
Application number
IL13712199A
Other languages
English (en)
Original Assignee
Miller Jonathan L
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Miller Jonathan L filed Critical Miller Jonathan L
Publication of IL137121A0 publication Critical patent/IL137121A0/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565Complementarity determining region [CDR]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/60Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
    • C07K2317/62Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
    • C07K2317/622Single chain antibody (scFv)

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Hematology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
IL13712199A 1998-10-30 1999-10-29 Variable heavy chain and variable light chain regions of antibodies to human platelet glycoprotein ib alpha IL137121A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10627598P 1998-10-30 1998-10-30
PCT/US1999/025495 WO2000026667A1 (en) 1998-10-30 1999-10-29 Variable heavy chain and variable light chain regions of antibodies to human platelet glycoprotein ib alpha

Publications (1)

Publication Number Publication Date
IL137121A0 true IL137121A0 (en) 2001-06-14

Family

ID=22310524

Family Applications (1)

Application Number Title Priority Date Filing Date
IL13712199A IL137121A0 (en) 1998-10-30 1999-10-29 Variable heavy chain and variable light chain regions of antibodies to human platelet glycoprotein ib alpha

Country Status (8)

Country Link
EP (1) EP1051620B1 (ja)
JP (1) JP2002529054A (ja)
AT (1) ATE329263T1 (ja)
AU (1) AU1458500A (ja)
CA (1) CA2317808A1 (ja)
DE (1) DE69931756T2 (ja)
IL (1) IL137121A0 (ja)
WO (1) WO2000026667A1 (ja)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9918788D0 (en) 1999-08-10 1999-10-13 Leuven K U Res & Dev Antithrombotic effect of platelet glycoprotein 1b blocking monoclonal Fab fragments
DE10019967A1 (de) * 2000-04-20 2001-10-25 Fenning Biomed Gmbh Dr Antikörper gegen natives gp96, deren Herstellung und Verwendung
US7521053B2 (en) 2001-10-11 2009-04-21 Amgen Inc. Angiopoietin-2 specific binding agents
US7658924B2 (en) 2001-10-11 2010-02-09 Amgen Inc. Angiopoietin-2 specific binding agents
EP1539235A2 (en) 2002-07-01 2005-06-15 Human Genome Sciences, Inc. Antibodies that specifically bind to reg iv
WO2004005890A2 (en) * 2002-07-03 2004-01-15 The Trustees Of The University Of Pennsylvania Compositions, methods and kits relating to anti-platelet autoantibodies and inhibitors thereof
AU2003298112A1 (en) * 2002-11-13 2004-06-03 Micromet Ag Method for identifying antigen specific b cells
AU2004259406A1 (en) * 2003-06-30 2005-02-03 Bio-Technology General (Israel) Ltd. Antibodies and uses thereof
EP1749536A1 (en) * 2005-08-03 2007-02-07 Thrombotargets Europe, S.L. Activated factor X stimulants as new antihemorrhagic agents for topical use
JO2913B1 (en) 2008-02-20 2015-09-15 امجين إنك, Antibodies directed towards angiopoietin-1 and angiopoietin-2 proteins and their uses
DK2186829T3 (en) * 2008-11-14 2015-04-07 Canadian Blood Services Antibodies to GPIbalfa
CN102905727B (zh) * 2009-10-30 2016-12-07 詹森生物科技公司 Il-17a拮抗剂
PE20221325A1 (es) * 2019-12-10 2022-09-09 Ccoa Therapeutics Inc Anticuerpos anti-glicoproteina ib alfa humanizada (gpibalpha)
BR112022011957A2 (pt) * 2019-12-20 2022-09-06 Medimmune Llc Composições e métodos de tratamento de câncer com receptores de antígenos quiméricos visando glipicana 3
BR112022025632A2 (pt) * 2020-06-23 2023-01-17 Kadmon Corp Llc Anticorpos anti-pd-1 e proteínas de fusão

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5877155A (en) * 1995-03-17 1999-03-02 The Research Foundation Of State University Of New York Mimotopes and anti-mimotopes of human platelet glycoprotein Ib/IX
US5817748A (en) * 1995-03-17 1998-10-06 The Research Foundation Of State University Of New York Mimotopes of human Platelet glycoprotein Ib/IX

Also Published As

Publication number Publication date
ATE329263T1 (de) 2006-06-15
DE69931756D1 (de) 2006-07-20
CA2317808A1 (en) 2000-05-11
AU1458500A (en) 2000-05-22
JP2002529054A (ja) 2002-09-10
WO2000026667A1 (en) 2000-05-11
EP1051620A4 (en) 2005-01-12
DE69931756T2 (de) 2007-05-24
EP1051620A1 (en) 2000-11-15
WO2000026667A9 (en) 2001-04-12
EP1051620B1 (en) 2006-06-07

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