IL134169A0 - Method for the racemic biochemical resolution of cis- and trans-pyrrolopiperidine - Google Patents

Method for the racemic biochemical resolution of cis- and trans-pyrrolopiperidine

Info

Publication number
IL134169A0
IL134169A0 IL13416998A IL13416998A IL134169A0 IL 134169 A0 IL134169 A0 IL 134169A0 IL 13416998 A IL13416998 A IL 13416998A IL 13416998 A IL13416998 A IL 13416998A IL 134169 A0 IL134169 A0 IL 134169A0
Authority
IL
Israel
Prior art keywords
pyrrolopiperidine
racemic
cis
trans
biochemical
Prior art date
Application number
IL13416998A
Other languages
English (en)
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of IL134169A0 publication Critical patent/IL134169A0/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/18Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
    • C12P17/182Heterocyclic compounds containing nitrogen atoms as the only ring heteroatoms in the condensed system
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • C12P41/006Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by reactions involving C-N bonds, e.g. nitriles, amides, hydantoins, carbamates, lactames, transamination reactions, or keto group formation from racemic mixtures
    • C12P41/007Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by reactions involving C-N bonds, e.g. nitriles, amides, hydantoins, carbamates, lactames, transamination reactions, or keto group formation from racemic mixtures by reactions involving acyl derivatives of racemic amines

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Genetics & Genomics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Hydrogenated Pyridines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
IL13416998A 1997-08-14 1998-08-01 Method for the racemic biochemical resolution of cis- and trans-pyrrolopiperidine IL134169A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19735198A DE19735198A1 (de) 1997-08-14 1997-08-14 Verfahren zur Racematspaltung von cis- und trans-Pyrrolopiperidin
PCT/EP1998/004820 WO1999009200A1 (de) 1997-08-14 1998-08-01 Verfahren zur racematspaltung von cis- und trans- pyrrolopiperidin

Publications (1)

Publication Number Publication Date
IL134169A0 true IL134169A0 (en) 2001-04-30

Family

ID=7838922

Family Applications (1)

Application Number Title Priority Date Filing Date
IL13416998A IL134169A0 (en) 1997-08-14 1998-08-01 Method for the racemic biochemical resolution of cis- and trans-pyrrolopiperidine

Country Status (11)

Country Link
US (1) US6153414A (de)
EP (1) EP1003902A1 (de)
JP (1) JP2001514901A (de)
KR (1) KR20010022843A (de)
CN (1) CN1267334A (de)
AU (1) AU9158098A (de)
CA (1) CA2300119A1 (de)
DE (1) DE19735198A1 (de)
HU (1) HUP0004660A3 (de)
IL (1) IL134169A0 (de)
WO (1) WO1999009200A1 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7692015B2 (en) * 2007-01-05 2010-04-06 Zheqing Wang Economical process for preparing (S, S)-2, 8-diazabicyclo[4.3.0]nonane and its enantiomer
IT1393337B1 (it) * 2009-03-06 2012-04-20 Italiana Sint Spa Sintesi di (4as, 7as)-ottaidro-1h-pirrolo[3,4-b]piridina
CN103044418B (zh) * 2011-10-14 2015-02-04 上海朴颐化学科技有限公司 (s,s)-2,8-二氮杂双环[4,3,0]壬烷的不对称合成方法、相关原料及制备方法
CN104672234B (zh) * 2015-02-14 2016-01-27 佛山市赛维斯医药科技有限公司 一类含双酰胺结构的FXa抑制剂、制备方法及其用途

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW209865B (de) * 1992-01-10 1993-07-21 Bayer Ag
KR0148277B1 (ko) * 1993-01-18 1998-11-02 채영복 신규한 플루오르퀴놀론계 유도체 및 그의 제조방법
DE4332738A1 (de) * 1993-09-25 1995-03-30 Basf Ag Racematspaltung primärer und sekundärer Amine durch Enzym-katalysierte Acylierung
GB9321325D0 (en) * 1993-10-15 1993-12-08 Chiros Ltd Microorganism and its use

Also Published As

Publication number Publication date
CA2300119A1 (en) 1999-02-25
HUP0004660A2 (hu) 2001-04-28
US6153414A (en) 2000-11-28
AU9158098A (en) 1999-03-08
KR20010022843A (ko) 2001-03-26
JP2001514901A (ja) 2001-09-18
EP1003902A1 (de) 2000-05-31
CN1267334A (zh) 2000-09-20
HUP0004660A3 (en) 2004-04-28
WO1999009200A1 (de) 1999-02-25
DE19735198A1 (de) 1999-02-18

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