IL132524A - Crystalline state of napazodone hydrochloride dehydrate and process for its production - Google Patents
Crystalline state of napazodone hydrochloride dehydrate and process for its productionInfo
- Publication number
- IL132524A IL132524A IL13252499A IL13252499A IL132524A IL 132524 A IL132524 A IL 132524A IL 13252499 A IL13252499 A IL 13252499A IL 13252499 A IL13252499 A IL 13252499A IL 132524 A IL132524 A IL 132524A
- Authority
- IL
- Israel
- Prior art keywords
- nefazodone
- purification
- crystalline
- hydrochloride dihydrate
- organic solvent
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
- C07D249/10—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D249/12—Oxygen or sulfur atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES009802223A ES2152860B1 (es) | 1998-10-23 | 1998-10-23 | Forma cristalina de la nefazodona y procedimiento para su preparacion. |
Publications (2)
Publication Number | Publication Date |
---|---|
IL132524A0 IL132524A0 (en) | 2001-03-19 |
IL132524A true IL132524A (en) | 2001-11-25 |
Family
ID=8305559
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL13252499A IL132524A (en) | 1998-10-23 | 1999-10-21 | Crystalline state of napazodone hydrochloride dehydrate and process for its production |
Country Status (5)
Country | Link |
---|---|
US (1) | US6448404B1 (es) |
EP (1) | EP1000944A1 (es) |
CA (1) | CA2287105A1 (es) |
ES (1) | ES2152860B1 (es) |
IL (1) | IL132524A (es) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2356450C (en) | 2001-09-10 | 2003-11-25 | Brantford Chemicals Inc. | An improved process for the preparation of nefazodone hydrochloride |
DE102004021494B4 (de) * | 2004-04-30 | 2006-04-06 | Man Roland Druckmaschinen Ag | Vorrichtung zum Auf- und Abziehen einer Hülse |
WO2012072665A1 (en) | 2010-11-30 | 2012-06-07 | Pharmaneuroboost N.V. | Compositions comprising pipamperone and serotonin antagonist reuptake inhibitors |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1052119B (it) * | 1972-10-16 | 1981-06-20 | Sigma Tau Ind Farmaceuti | Derivati del triazolinone e procedimento per la loro preparazione |
US4338317A (en) * | 1981-03-16 | 1982-07-06 | Mead Johnson & Company | Phenoxyethyl-1,2,4,-triazol-3-one antidepressants |
US4487773A (en) * | 1981-03-16 | 1984-12-11 | Mead Johnson & Company | 1,2,4-Triazol-3-one antidepressants |
US5256664A (en) * | 1992-04-28 | 1993-10-26 | Bristol-Myers Squibb Company | Antidepressant 3-halophenylpiperazinylpropyl derivatives of substituted triazolones and triazoldiones |
IT1256387B (it) * | 1992-11-13 | 1995-12-04 | Acraf | Procedimento per preparare triazoloni |
CA2160423A1 (en) * | 1994-11-02 | 1996-05-03 | Hemant N. Joshi | Salts of nefazodone having improved dissolution rates |
EA199800867A1 (ru) * | 1996-03-25 | 1999-02-25 | Эли Лилли Энд Компани | Соединения тетрагидробетакарболина |
-
1998
- 1998-10-23 ES ES009802223A patent/ES2152860B1/es not_active Expired - Fee Related
-
1999
- 1999-10-15 US US09/418,760 patent/US6448404B1/en not_active Expired - Fee Related
- 1999-10-18 EP EP99500188A patent/EP1000944A1/en not_active Withdrawn
- 1999-10-21 IL IL13252499A patent/IL132524A/en not_active IP Right Cessation
- 1999-10-22 CA CA002287105A patent/CA2287105A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
IL132524A0 (en) | 2001-03-19 |
ES2152860B1 (es) | 2001-08-16 |
CA2287105A1 (en) | 2000-04-23 |
EP1000944A1 (en) | 2000-05-17 |
US6448404B1 (en) | 2002-09-10 |
ES2152860A1 (es) | 2001-02-01 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
KB | Patent renewed | ||
KB | Patent renewed | ||
MM9K | Patent not in force due to non-payment of renewal fees |