IL131670A - Use of 2,3,4,5-tetrahydro-1h-3-benzazepines for the manufacture of a pharmaceutical composition for the treatment of sleep disorders - Google Patents
Use of 2,3,4,5-tetrahydro-1h-3-benzazepines for the manufacture of a pharmaceutical composition for the treatment of sleep disordersInfo
- Publication number
- IL131670A IL131670A IL13167098A IL13167098A IL131670A IL 131670 A IL131670 A IL 131670A IL 13167098 A IL13167098 A IL 13167098A IL 13167098 A IL13167098 A IL 13167098A IL 131670 A IL131670 A IL 131670A
- Authority
- IL
- Israel
- Prior art keywords
- manufacture
- bridge
- hydrogen
- treatment
- pharmaceutical composition
- Prior art date
Links
- 208000019116 sleep disease Diseases 0.000 title abstract 3
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- MWVMYAWMFTVYED-UHFFFAOYSA-N 2,3,4,5-tetrahydro-1h-3-benzazepine Chemical class C1CNCCC2=CC=CC=C21 MWVMYAWMFTVYED-UHFFFAOYSA-N 0.000 title 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 4
- 239000001257 hydrogen Substances 0.000 abstract 4
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- 150000002431 hydrogen Chemical group 0.000 abstract 3
- 229910052736 halogen Inorganic materials 0.000 abstract 2
- 150000002367 halogens Chemical class 0.000 abstract 2
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 208000022925 sleep disturbance Diseases 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Epidemiology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Anesthesiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DK26597 | 1997-03-12 | ||
| US4150997P | 1997-03-24 | 1997-03-24 | |
| PCT/DK1998/000088 WO1998040072A1 (en) | 1997-03-12 | 1998-03-11 | Use of 2,3,4,5-tetrahydro-1h-3-benzazepines for the manufacture of a pharmaceutical composition for the treatment of sleep disorders |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL131670A0 IL131670A0 (en) | 2001-01-28 |
| IL131670A true IL131670A (en) | 2005-07-25 |
Family
ID=26063641
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL13167098A IL131670A (en) | 1997-03-12 | 1998-03-11 | Use of 2,3,4,5-tetrahydro-1h-3-benzazepines for the manufacture of a pharmaceutical composition for the treatment of sleep disorders |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US6211173B1 (de) |
| EP (1) | EP1011679B1 (de) |
| JP (1) | JP2001515484A (de) |
| AT (1) | ATE245986T1 (de) |
| AU (1) | AU742873B2 (de) |
| BR (1) | BR9808234A (de) |
| CA (1) | CA2283083C (de) |
| CZ (1) | CZ296464B6 (de) |
| DE (1) | DE69816832T2 (de) |
| DK (1) | DK1011679T3 (de) |
| ES (1) | ES2203933T3 (de) |
| IL (1) | IL131670A (de) |
| NO (1) | NO324719B1 (de) |
| PL (1) | PL189822B1 (de) |
| PT (1) | PT1011679E (de) |
| WO (1) | WO1998040072A1 (de) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2005035504A2 (en) * | 2003-05-22 | 2005-04-21 | Schering Corporation | 5-h -benzo [d] naphth [2, 1-b] azepine derivative as selective d1/d5 receptor antagonists for the treatment of obesity and cns disorders |
| WO2005060968A1 (en) * | 2003-12-11 | 2005-07-07 | Sepracor Inc. | Combination of a sedative and a neurotransmitter modulator, and methods for improving sleep quality and treating depression |
| US20050215521A1 (en) * | 2003-12-22 | 2005-09-29 | Karim Lalji | Modafinil combination therapy for improving sleep quality |
| EP1696959A2 (de) * | 2003-12-24 | 2006-09-06 | Sepracor, Inc. | Melatonin-kombinationstherapie zur verbesserung der schlafqualität |
| CA2556870C (en) * | 2004-02-18 | 2014-01-28 | Timothy J. Barberich | Dopamine-agonist combination therapy for improving sleep quality |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK325188D0 (da) | 1988-06-15 | 1988-06-15 | Novo Industri As | Hidtil ukendte benzazepinderivater |
| US5470850A (en) | 1992-02-24 | 1995-11-28 | Novo Nordisk A/S | 2,3,4,5-tetrahydro-1H-3-benzazepines |
| DK26793D0 (da) | 1993-03-10 | 1993-03-10 | Novo Nordisk As | Benzofuranyl- eller dihydrobenzofuranyl-substituerede tricycliske benzazepiner, der anvendelse og fremstilling |
-
1998
- 1998-03-11 IL IL13167098A patent/IL131670A/xx not_active IP Right Cessation
- 1998-03-11 AU AU66100/98A patent/AU742873B2/en not_active Ceased
- 1998-03-11 CZ CZ0317799A patent/CZ296464B6/cs not_active IP Right Cessation
- 1998-03-11 ES ES98907896T patent/ES2203933T3/es not_active Expired - Lifetime
- 1998-03-11 AT AT98907896T patent/ATE245986T1/de active
- 1998-03-11 EP EP98907896A patent/EP1011679B1/de not_active Expired - Lifetime
- 1998-03-11 BR BR9808234-5A patent/BR9808234A/pt not_active Application Discontinuation
- 1998-03-11 WO PCT/DK1998/000088 patent/WO1998040072A1/en not_active Ceased
- 1998-03-11 CA CA002283083A patent/CA2283083C/en not_active Expired - Fee Related
- 1998-03-11 US US09/380,840 patent/US6211173B1/en not_active Expired - Fee Related
- 1998-03-11 JP JP53910298A patent/JP2001515484A/ja not_active Ceased
- 1998-03-11 PL PL98335545A patent/PL189822B1/pl not_active IP Right Cessation
- 1998-03-11 DK DK98907896T patent/DK1011679T3/da active
- 1998-03-11 DE DE69816832T patent/DE69816832T2/de not_active Expired - Lifetime
- 1998-03-11 PT PT98907896T patent/PT1011679E/pt unknown
-
1999
- 1999-09-07 NO NO19994343A patent/NO324719B1/no not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| IL131670A0 (en) | 2001-01-28 |
| CA2283083C (en) | 2007-09-04 |
| JP2001515484A (ja) | 2001-09-18 |
| EP1011679B1 (de) | 2003-07-30 |
| AU742873B2 (en) | 2002-01-17 |
| AU6610098A (en) | 1998-09-29 |
| ATE245986T1 (de) | 2003-08-15 |
| BR9808234A (pt) | 2000-05-16 |
| DE69816832D1 (de) | 2003-09-04 |
| CZ317799A3 (cs) | 2000-03-15 |
| PL335545A1 (en) | 2000-04-25 |
| PT1011679E (pt) | 2003-12-31 |
| DK1011679T3 (da) | 2003-11-24 |
| CZ296464B6 (cs) | 2006-03-15 |
| NO994343D0 (no) | 1999-09-07 |
| US6211173B1 (en) | 2001-04-03 |
| CA2283083A1 (en) | 1998-09-17 |
| NO994343L (no) | 1999-11-11 |
| NO324719B1 (no) | 2007-12-03 |
| DE69816832T2 (de) | 2004-05-27 |
| EP1011679A1 (de) | 2000-06-28 |
| ES2203933T3 (es) | 2004-04-16 |
| WO1998040072A1 (en) | 1998-09-17 |
| PL189822B1 (pl) | 2005-09-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| HP | Change in proprietorship | ||
| FF | Patent granted | ||
| KB | Patent renewed | ||
| MM9K | Patent not in force due to non-payment of renewal fees |