IL131243A - History - (4 Piperidinyl) - 2-1H - Benzofiran, their preparation and pharmaceutical preparations containing them - Google Patents
History - (4 Piperidinyl) - 2-1H - Benzofiran, their preparation and pharmaceutical preparations containing themInfo
- Publication number
- IL131243A IL131243A IL13124398A IL13124398A IL131243A IL 131243 A IL131243 A IL 131243A IL 13124398 A IL13124398 A IL 13124398A IL 13124398 A IL13124398 A IL 13124398A IL 131243 A IL131243 A IL 131243A
- Authority
- IL
- Israel
- Prior art keywords
- compound
- cis
- benzopyran
- dihydro
- piperidinyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/453—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with oxygen as a ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/10—Spiro-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Neurology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Psychiatry (AREA)
- Epidemiology (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US79710797A | 1997-02-07 | 1997-02-07 | |
| PCT/US1998/000979 WO1998034933A1 (en) | 1997-02-07 | 1998-01-20 | (4-piperidinyl)-1h-2-benzopyran derivatives useful as antipsychotic agents |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL131243A0 IL131243A0 (en) | 2001-01-28 |
| IL131243A true IL131243A (en) | 2004-02-19 |
Family
ID=25169927
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL13124398A IL131243A (en) | 1997-02-07 | 1998-01-20 | History - (4 Piperidinyl) - 2-1H - Benzofiran, their preparation and pharmaceutical preparations containing them |
Country Status (22)
| Country | Link |
|---|---|
| EP (1) | EP1015446B1 (no) |
| JP (1) | JP4177461B2 (no) |
| KR (1) | KR100509878B1 (no) |
| CN (1) | CN1092653C (no) |
| AR (1) | AR011614A1 (no) |
| AT (1) | ATE236150T1 (no) |
| AU (1) | AU725301B2 (no) |
| BR (1) | BRPI9807312B8 (no) |
| CA (1) | CA2281702C (no) |
| CY (1) | CY2324B1 (no) |
| DE (1) | DE69812980T2 (no) |
| DK (1) | DK1015446T3 (no) |
| ES (1) | ES2194303T3 (no) |
| HK (1) | HK1027812A1 (no) |
| HU (1) | HUP0001308A3 (no) |
| IL (1) | IL131243A (no) |
| NO (1) | NO318936B1 (no) |
| NZ (1) | NZ336719A (no) |
| PT (1) | PT1015446E (no) |
| TW (1) | TW518333B (no) |
| WO (1) | WO1998034933A1 (no) |
| ZA (1) | ZA98831B (no) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK1749001T3 (da) * | 2004-04-29 | 2010-06-28 | Aventis Pharma Inc | 3-piperidinylisochroman-5-ol som dopaminagonister |
| PL1748767T3 (pl) | 2004-05-28 | 2012-08-31 | Unigen Inc | 1-(3-metylo-2,4-dimetoksyfenylo)-3-(2',4'-dihydroksyfenylo)-propan jako silny inhibitor tyrozynazy |
| EP2183245B1 (en) | 2007-07-26 | 2014-07-09 | F. Hoffmann-La Roche AG | Dual modulators of 5-ht2a and d3 receptors |
| JP2011528719A (ja) | 2008-07-21 | 2011-11-24 | ユニジェン・インコーポレーテッド | スキンホワイトニング（色を薄くする）化合物系列 |
| US8877778B2 (en) | 2010-12-15 | 2014-11-04 | Hoffmann-La Roche Inc. | Benzofurane compounds |
| CN102079720B (zh) * | 2011-01-20 | 2013-02-06 | 蚌埠丰原医药科技发展有限公司 | 一种制备1-苄基-4-哌啶甲醛的方法 |
| CN109180448A (zh) | 2011-03-24 | 2019-01-11 | 尤尼根公司 | 用于制备二芳基丙烷的化合物和方法 |
| US8921397B2 (en) | 2011-05-04 | 2014-12-30 | Hoffmann-La Roche Inc. | Benzofurane-piperidine compounds |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1552004A (en) * | 1976-05-26 | 1979-09-05 | Takeda Chemical Industries Ltd | Isochroman derivatives |
| US4963568A (en) * | 1989-05-31 | 1990-10-16 | Abbott Laboratories | Dopamine agonists |
-
1998
- 1998-01-20 NZ NZ336719A patent/NZ336719A/xx unknown
- 1998-01-20 AU AU59237/98A patent/AU725301B2/en not_active Expired
- 1998-01-20 WO PCT/US1998/000979 patent/WO1998034933A1/en active IP Right Grant
- 1998-01-20 IL IL13124398A patent/IL131243A/en not_active IP Right Cessation
- 1998-01-20 HU HU0001308A patent/HUP0001308A3/hu unknown
- 1998-01-20 ES ES98902628T patent/ES2194303T3/es not_active Expired - Lifetime
- 1998-01-20 CA CA002281702A patent/CA2281702C/en not_active Expired - Lifetime
- 1998-01-20 EP EP98902628A patent/EP1015446B1/en not_active Expired - Lifetime
- 1998-01-20 KR KR10-1999-7007127A patent/KR100509878B1/ko not_active IP Right Cessation
- 1998-01-20 JP JP53461798A patent/JP4177461B2/ja not_active Expired - Fee Related
- 1998-01-20 DK DK98902628T patent/DK1015446T3/da active
- 1998-01-20 PT PT98902628T patent/PT1015446E/pt unknown
- 1998-01-20 BR BRPI9807312A patent/BRPI9807312B8/pt not_active IP Right Cessation
- 1998-01-20 CN CN98802357A patent/CN1092653C/zh not_active Expired - Lifetime
- 1998-01-20 DE DE69812980T patent/DE69812980T2/de not_active Expired - Lifetime
- 1998-01-20 AT AT98902628T patent/ATE236150T1/de active
- 1998-02-02 ZA ZA98831A patent/ZA98831B/xx unknown
- 1998-02-03 AR ARP980100456A patent/AR011614A1/es active IP Right Grant
- 1998-02-03 TW TW087101327A patent/TW518333B/zh not_active IP Right Cessation
-
1999
- 1999-08-06 NO NO19993812A patent/NO318936B1/no unknown
-
2000
- 2000-11-09 HK HK00107146A patent/HK1027812A1/xx not_active IP Right Cessation
-
2003
- 2003-04-30 CY CY0300037A patent/CY2324B1/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| BRPI9807312B8 (pt) | 2016-09-13 |
| PT1015446E (pt) | 2003-08-29 |
| HUP0001308A3 (en) | 2001-07-30 |
| WO1998034933A1 (en) | 1998-08-13 |
| CN1246859A (zh) | 2000-03-08 |
| JP4177461B2 (ja) | 2008-11-05 |
| CY2324B1 (en) | 2003-11-14 |
| EP1015446B1 (en) | 2003-04-02 |
| DE69812980T2 (de) | 2003-11-13 |
| ZA98831B (en) | 1998-08-07 |
| AR011614A1 (es) | 2000-08-30 |
| AU725301B2 (en) | 2000-10-12 |
| ATE236150T1 (de) | 2003-04-15 |
| KR100509878B1 (ko) | 2005-08-25 |
| TW518333B (en) | 2003-01-21 |
| CN1092653C (zh) | 2002-10-16 |
| KR20000070862A (ko) | 2000-11-25 |
| EP1015446A1 (en) | 2000-07-05 |
| HUP0001308A2 (hu) | 2001-06-28 |
| NO318936B1 (no) | 2005-05-30 |
| BR9807312A (pt) | 2000-05-02 |
| CA2281702A1 (en) | 1998-08-13 |
| JP2001512436A (ja) | 2001-08-21 |
| BR9807312B1 (pt) | 2013-10-29 |
| DE69812980D1 (de) | 2003-05-08 |
| ES2194303T3 (es) | 2003-11-16 |
| NO993812D0 (no) | 1999-08-06 |
| DK1015446T3 (da) | 2003-07-14 |
| AU5923798A (en) | 1998-08-26 |
| NO993812L (no) | 1999-10-05 |
| NZ336719A (en) | 2000-10-27 |
| HK1027812A1 (en) | 2001-01-23 |
| IL131243A0 (en) | 2001-01-28 |
| CA2281702C (en) | 2006-04-11 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| KR900001184B1 (ko) | N-아르알킬 피페리딘메탄올 유도체의 제조방법 | |
| CZ220797A3 (cs) | Sloučeniny, mající vlivy na systémy spojené se serotoninem | |
| JP3819934B2 (ja) | ニューロキニンａアンタゴニストとしての環状アミド誘導体 | |
| JP5936669B2 (ja) | ケモカイン受容体アンタゴニストおよびその使用方法 | |
| MXPA05002835A (es) | Derivados de azaheterociclilmetilo de benzodioxanos fusionados con heterociclos antidepresivos. | |
| CA2240964C (en) | Piperidone tachykinin antagonists | |
| EP1015446B1 (en) | (4-piperidinyl)-1h-2-benzopyran derivatives useful as antipsychotic agents | |
| US9663537B2 (en) | Chemokine receptor antagonists and methods of use | |
| US6004982A (en) | 4-piperidinyl) H-2-benzopyran derivatives useful as antipsychotic agents | |
| JP4748162B2 (ja) | Ｎ−ジヒドロキシアルキル置換２−オキソイミダゾール誘導体 | |
| EP1613594B1 (en) | 4-(2-phenylsulfanyl-phenyl)-1,2,3,6-tetrahydropyridine derivatives as serotonin reuptake inhibitors | |
| EA008060B1 (ru) | Антагонисты хемокинного рецептора и способы их применения | |
| US20050070549A1 (en) | Chemokine receptor antagonists and methods of use thereof | |
| US4481360A (en) | 4H-1,2,4-Triazol-3-yl compounds | |
| MXPA99007307A (es) | Derivados de (4-piperidinil)-1h-2-benzopirano utiles como agentes antipsicoticos | |
| PT846683E (pt) | Derivados de 4-hidroxi-piperidina | |
| EP0745591B1 (en) | Indanylpiperidines as melatonergic agents |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ERR | Corrigendum |
Free format text: JOURNAL 12/2003 P. 3658 PATENT APPLICATION NO. 131243 CORRECT TITLE OF INVENTION TO:...1H-2-BENZOPYRAN... |
|
| FF | Patent granted | ||
| KB | Patent renewed | ||
| KB | Patent renewed | ||
| KB | Patent renewed | ||
| EXP | Patent expired |