IL129957A - Substituted phenols and phenyl esters and pharmaceutical compositions containing them - Google Patents
Substituted phenols and phenyl esters and pharmaceutical compositions containing themInfo
- Publication number
- IL129957A IL129957A IL12995797A IL12995797A IL129957A IL 129957 A IL129957 A IL 129957A IL 12995797 A IL12995797 A IL 12995797A IL 12995797 A IL12995797 A IL 12995797A IL 129957 A IL129957 A IL 129957A
- Authority
- IL
- Israel
- Prior art keywords
- pharmaceutical compositions
- compositions containing
- substituted phenols
- phenyl esters
- esters
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/10—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and singly-bound oxygen atoms bound to the same carbon skeleton
- C07C323/18—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and singly-bound oxygen atoms bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton
- C07C323/20—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and singly-bound oxygen atoms bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton with singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/06—Free radical scavengers or antioxidants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C39/00—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring
- C07C39/18—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring monocyclic with unsaturation outside the aromatic ring
- C07C39/19—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring monocyclic with unsaturation outside the aromatic ring containing carbon-to-carbon double bonds but no carbon-to-carbon triple bonds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C43/00—Ethers; Compounds having groups, groups or groups
- C07C43/02—Ethers
- C07C43/20—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
- C07C43/23—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring containing hydroxy or O-metal groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/017—Esters of hydroxy compounds having the esterified hydroxy group bound to a carbon atom of a six-membered aromatic ring
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Diabetes (AREA)
- Immunology (AREA)
- Hematology (AREA)
- Rheumatology (AREA)
- Obesity (AREA)
- Pulmonology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Toxicology (AREA)
- Emergency Medicine (AREA)
- Transplantation (AREA)
- Biochemistry (AREA)
- Urology & Nephrology (AREA)
- Pain & Pain Management (AREA)
- Endocrinology (AREA)
- Vascular Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Anti-Oxidant Or Stabilizer Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US75552896A | 1996-11-20 | 1996-11-20 | |
| PCT/US1997/018055 WO1998022418A1 (en) | 1996-11-20 | 1997-10-07 | Substituted phenols and thiophenols useful as antioxidant agents |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL129957A0 IL129957A0 (en) | 2000-02-29 |
| IL129957A true IL129957A (en) | 2005-06-19 |
Family
ID=25039544
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL12995797A IL129957A (en) | 1996-11-20 | 1997-10-07 | Substituted phenols and phenyl esters and pharmaceutical compositions containing them |
Country Status (22)
| Country | Link |
|---|---|
| EP (1) | EP0942896B1 (pt) |
| JP (2) | JP4267705B2 (pt) |
| KR (2) | KR100648118B1 (pt) |
| CN (1) | CN1168693C (pt) |
| AR (1) | AR009429A1 (pt) |
| AT (1) | ATE237574T1 (pt) |
| AU (1) | AU734050B2 (pt) |
| BR (1) | BR9713372A (pt) |
| CA (1) | CA2271054C (pt) |
| DE (1) | DE69721040T2 (pt) |
| DK (1) | DK0942896T3 (pt) |
| ES (1) | ES2191828T3 (pt) |
| HK (1) | HK1021970A1 (pt) |
| HU (1) | HUP9904244A3 (pt) |
| IL (1) | IL129957A (pt) |
| NO (1) | NO318039B1 (pt) |
| NZ (1) | NZ335440A (pt) |
| PT (1) | PT942896E (pt) |
| SI (1) | SI0942896T1 (pt) |
| TW (1) | TW508349B (pt) |
| WO (1) | WO1998022418A1 (pt) |
| ZA (1) | ZA9710315B (pt) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6852878B2 (en) | 1998-05-14 | 2005-02-08 | Atherogenics, Inc. | Thioketals and thioethers for inhibiting the expression of VCAM-1 |
| US6670398B2 (en) | 1997-05-14 | 2003-12-30 | Atherogenics, Inc. | Compounds and methods for treating transplant rejection |
| DK0981343T3 (da) | 1997-05-14 | 2006-01-30 | Atherogenics Inc | Probucolmonoestere til behandling af kardiovaskulær og inflammatorisk sygdom |
| EP1695959A1 (en) * | 1997-05-14 | 2006-08-30 | Atherogenics, Inc. | Compouds and methods for the inhibition of the expression of VCAM-1 |
| US6020383A (en) * | 1999-01-11 | 2000-02-01 | Eastman Chemicals Company | Method for reducing blood cholesterol and/or blood triglycerides |
| CN100512809C (zh) * | 2001-10-25 | 2009-07-15 | 阿特罗吉尼克斯公司 | 化合物在制备用于慢性移植排斥的药物中的用途 |
| WO2005102323A2 (en) | 2004-04-20 | 2005-11-03 | Atherogenics, Inc. | Process of preparing esters and ethers of probucol and derivatives thereof |
| KR100725582B1 (ko) | 2004-06-29 | 2007-06-08 | 주식회사 동부하이텍 | 식물병원균의 생장억제활성을 갖는 알킬페놀 유도체 |
| JP5191739B2 (ja) * | 2004-12-22 | 2013-05-08 | チバ ホールディング インコーポレーテッド | 抗ラジカル剤 |
| US8252840B2 (en) | 2007-03-26 | 2012-08-28 | Salutria Pharmaceuticals Llc | Methods of derivatives of probucol for the treatment of type II diabetes |
| KR101420083B1 (ko) * | 2012-04-04 | 2014-07-15 | 이화여자대학교 산학협력단 | Ｕｃｈ－ｌ１ 저해 화합물 또는 이의 약학적으로 허용가능한 염을 유효성분으로 함유하는 ｕｃｈ－ｌ１ 관련 질환의 예방 또는 치료용 약학적 조성물 |
| WO2014185561A1 (ko) * | 2013-05-13 | 2014-11-20 | 이화여자대학교 산학협력단 | 신규한 화합물 또는 이의 약학적으로 허용 가능한 염 및 이를 유효성분으로 함유하는 ｕｃｈ－ｌ１ 관련 질환의 예방 또는 치료용 약학적 조성물 |
| WO2016170704A1 (ja) * | 2015-04-23 | 2016-10-27 | 株式会社日本ハイポックス | 慢性呼吸器疾患治療剤及び心臓の線維化抑制組成物 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS57176038A (en) * | 1981-04-21 | 1982-10-29 | Fuji Photo Film Co Ltd | Silver halide color photographic material |
| CA2050514A1 (en) * | 1990-09-14 | 1992-03-15 | Bradley C. Pearce | Acyclic tocotrienol analogs in the treatment of hypercholesterolemia and hyperlipidemia |
| DE4109627A1 (de) * | 1991-03-23 | 1992-09-24 | Boehringer Mannheim Gmbh | Neue phenolether, verfahren zu ihrer herstellung und arzneimittel, die diese verbindungen enthalten |
| CA2096496A1 (en) * | 1992-05-29 | 1993-11-30 | Bradley C. Pearce | Acyclic tocotrienol analogs in the treatment of hypercholesterolemia and hyperlipidemia |
| EP0589069B1 (en) * | 1992-09-18 | 1997-01-29 | Nippon Hypox Laboratories Incorporated | Hydroquinone derivatives and antioxidants and tumor inhibitors containing them |
| JP3050733B2 (ja) * | 1992-10-16 | 2000-06-12 | 中外製薬株式会社 | ４−アルコキシ−２，６−ジ−ｔ−ブチルフェノール誘導体 |
| TW393475B (en) * | 1992-10-16 | 2000-06-11 | Chugai Pharmaceutical Co Ltd | 4-alkoxyl-2,6-di-t-butyl phenol derivatives |
-
1997
- 1997-10-07 CA CA002271054A patent/CA2271054C/en not_active Expired - Fee Related
- 1997-10-07 JP JP52363998A patent/JP4267705B2/ja not_active Expired - Fee Related
- 1997-10-07 SI SI9730517T patent/SI0942896T1/xx unknown
- 1997-10-07 AT AT97910819T patent/ATE237574T1/de not_active IP Right Cessation
- 1997-10-07 PT PT97910819T patent/PT942896E/pt unknown
- 1997-10-07 KR KR1020067001270A patent/KR100648118B1/ko not_active IP Right Cessation
- 1997-10-07 DE DE69721040T patent/DE69721040T2/de not_active Expired - Lifetime
- 1997-10-07 BR BR9713372A patent/BR9713372A/pt not_active IP Right Cessation
- 1997-10-07 KR KR1019997004402A patent/KR100698995B1/ko not_active IP Right Cessation
- 1997-10-07 CN CNB971999104A patent/CN1168693C/zh not_active Expired - Fee Related
- 1997-10-07 ES ES97910819T patent/ES2191828T3/es not_active Expired - Lifetime
- 1997-10-07 DK DK97910819T patent/DK0942896T3/da active
- 1997-10-07 WO PCT/US1997/018055 patent/WO1998022418A1/en not_active Application Discontinuation
- 1997-10-07 HU HU9904244A patent/HUP9904244A3/hu unknown
- 1997-10-07 AU AU48098/97A patent/AU734050B2/en not_active Ceased
- 1997-10-07 IL IL12995797A patent/IL129957A/xx not_active IP Right Cessation
- 1997-10-07 NZ NZ335440A patent/NZ335440A/en unknown
- 1997-10-07 EP EP97910819A patent/EP0942896B1/en not_active Expired - Lifetime
- 1997-11-14 ZA ZA9710315A patent/ZA9710315B/xx unknown
- 1997-11-15 TW TW086117094A patent/TW508349B/zh not_active IP Right Cessation
- 1997-11-17 AR ARP970105361A patent/AR009429A1/es not_active Application Discontinuation
-
1999
- 1999-05-19 NO NO19992390A patent/NO318039B1/no not_active IP Right Cessation
-
2000
- 2000-02-14 HK HK00100872A patent/HK1021970A1/xx not_active IP Right Cessation
-
2008
- 2008-11-19 JP JP2008295012A patent/JP2009132710A/ja active Pending
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| IL121236A0 (en) | Cycloalkano-pyridines their preparation and pharmaceutical compositions containing them | |
| IL122447A0 (en) | Pharmaceutical composition with anaestheric effect | |
| IL114622A0 (en) | Heteroaryl-oxazolidinones and pharmaceutical compositions containing them | |
| EG24118A (en) | Pharmaceutical compositions | |
| GB9615089D0 (en) | Esters and compositions comprising them | |
| HUP0000733A3 (en) | Aminoguanidines and alkoxyguanidines as and pharmaceutical compositions containing them | |
| EP0943327A4 (en) | DRUG | |
| HUP0001309A3 (en) | 1-phenyl-4-benzylpiperazines and pharmaceutical compositions containing them | |
| HUP9901452A3 (en) | Bicyclic-aromatic compounds and pharmaceutical compositions containing them | |
| IL128058A0 (en) | Illudin analogs and pharmaceutical compositions containing the same | |
| GB9616672D0 (en) | Pharmaceutical compositions | |
| GB9623205D0 (en) | Novel pharmaceutical compositions | |
| IL129957A (en) | Substituted phenols and phenyl esters and pharmaceutical compositions containing them | |
| PL331423A1 (en) | Muporocin and chlorohexidrin containing compositions | |
| GB9610359D0 (en) | Pharmaceutical compositions | |
| IL125998A0 (en) | Taxoids preparation thereof and pharmaceutical compositions containing them | |
| HUP0000460A3 (en) | Imidazopyridazines and pharmaceutical compositions thereof | |
| ZA979726B (en) | Pharmaceutical compositions | |
| GB9606429D0 (en) | Pharmaceutical compositions | |
| GB9613457D0 (en) | Pharmaceutical compositions | |
| SG87031A1 (en) | Cynanate ester composition and cured product thereof | |
| GB9623962D0 (en) | Pharmaceutical composition | |
| GB9618376D0 (en) | Pharmaceutical compositions | |
| GB9610136D0 (en) | Pharmaceutical compositions | |
| IL155070A0 (en) | Novel phenyl esters |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FF | Patent granted | ||
| KB | Patent renewed | ||
| KB | Patent renewed | ||
| MM9K | Patent not in force due to non-payment of renewal fees |