IL128927A0 - Substituted benzocycloheptapyridine derivatives useful for inhibition of farnesyl protein transferase - Google Patents
Substituted benzocycloheptapyridine derivatives useful for inhibition of farnesyl protein transferaseInfo
- Publication number
- IL128927A0 IL128927A0 IL12892797A IL12892797A IL128927A0 IL 128927 A0 IL128927 A0 IL 128927A0 IL 12892797 A IL12892797 A IL 12892797A IL 12892797 A IL12892797 A IL 12892797A IL 128927 A0 IL128927 A0 IL 128927A0
- Authority
- IL
- Israel
- Prior art keywords
- protein transferase
- inhibition
- farnesyl protein
- derivatives useful
- substituted
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
- C07F9/576—Six-membered rings
- C07F9/59—Hydrogenated pyridine rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6558—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
- C07F9/65583—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system each of the hetero rings containing nitrogen as ring hetero atom
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US71292496A | 1996-09-13 | 1996-09-13 | |
| PCT/US1997/015906 WO1998011100A1 (en) | 1996-09-13 | 1997-09-11 | Substituted benzocycloheptapyridine derivatives useful for inhibition of farnesyl protein transferase |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL128927A0 true IL128927A0 (en) | 2000-02-17 |
Family
ID=24864087
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL12892797A IL128927A0 (en) | 1996-09-13 | 1997-09-11 | Substituted benzocycloheptapyridine derivatives useful for inhibition of farnesyl protein transferase |
Country Status (20)
| Country | Link |
|---|---|
| EP (1) | EP0927179B1 (cs) |
| JP (1) | JP2001500509A (cs) |
| KR (1) | KR20000036112A (cs) |
| CN (1) | CN1109685C (cs) |
| AT (1) | ATE247106T1 (cs) |
| AU (1) | AU4337897A (cs) |
| BR (1) | BR9712825A (cs) |
| CA (1) | CA2264508C (cs) |
| CZ (1) | CZ84499A3 (cs) |
| DE (1) | DE69724130T2 (cs) |
| ES (1) | ES2205255T3 (cs) |
| HU (1) | HUP0000126A2 (cs) |
| ID (1) | ID22002A (cs) |
| IL (1) | IL128927A0 (cs) |
| NO (1) | NO991232L (cs) |
| NZ (1) | NZ334451A (cs) |
| PL (1) | PL332319A1 (cs) |
| SK (1) | SK33999A3 (cs) |
| TR (1) | TR199901189T2 (cs) |
| WO (1) | WO1998011100A1 (cs) |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4282233B1 (en) * | 1980-06-19 | 2000-09-05 | Schering Corp | Antihistaminic 11-(4-piperidylidene)-5h-benzoÄ5,6Ü-cyclohepta-Ä1,2Ü-pyridines |
| ES2164717T3 (es) * | 1993-10-15 | 2002-03-01 | Schering Corp | Compuestos triciclicos de sulfonamida utiles para inhibir la funcion de la proteina-g y para el tratamiento de enfermedades proliferativas. |
| IL111235A (en) * | 1993-10-15 | 2001-03-19 | Schering Plough Corp | Medicinal preparations for inhibiting protein G activity and for the treatment of malignant diseases, containing tricyclic compounds, some such new compounds and a process for the preparation of some of them |
-
1997
- 1997-09-11 JP JP10513764A patent/JP2001500509A/ja not_active Ceased
- 1997-09-11 EP EP97941479A patent/EP0927179B1/en not_active Expired - Lifetime
- 1997-09-11 KR KR1019997002135A patent/KR20000036112A/ko not_active Withdrawn
- 1997-09-11 NZ NZ334451A patent/NZ334451A/xx unknown
- 1997-09-11 CZ CZ99844A patent/CZ84499A3/cs unknown
- 1997-09-11 PL PL97332319A patent/PL332319A1/xx unknown
- 1997-09-11 ID IDW990088D patent/ID22002A/id unknown
- 1997-09-11 AT AT97941479T patent/ATE247106T1/de not_active IP Right Cessation
- 1997-09-11 WO PCT/US1997/015906 patent/WO1998011100A1/en active IP Right Grant
- 1997-09-11 BR BR9712825-2A patent/BR9712825A/pt unknown
- 1997-09-11 ES ES97941479T patent/ES2205255T3/es not_active Expired - Lifetime
- 1997-09-11 AU AU43378/97A patent/AU4337897A/en not_active Abandoned
- 1997-09-11 CA CA002264508A patent/CA2264508C/en not_active Expired - Fee Related
- 1997-09-11 IL IL12892797A patent/IL128927A0/xx unknown
- 1997-09-11 CN CN97199603A patent/CN1109685C/zh not_active Expired - Fee Related
- 1997-09-11 SK SK339-99A patent/SK33999A3/sk unknown
- 1997-09-11 DE DE69724130T patent/DE69724130T2/de not_active Expired - Fee Related
- 1997-09-11 TR TR1999/01189T patent/TR199901189T2/xx unknown
- 1997-09-11 HU HU0000126A patent/HUP0000126A2/hu unknown
-
1999
- 1999-03-12 NO NO991232A patent/NO991232L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| NZ334451A (en) | 2000-08-25 |
| ATE247106T1 (de) | 2003-08-15 |
| BR9712825A (pt) | 1999-11-23 |
| CZ84499A3 (cs) | 1999-08-11 |
| AU4337897A (en) | 1998-04-02 |
| EP0927179A1 (en) | 1999-07-07 |
| TR199901189T2 (xx) | 1999-07-21 |
| NO991232L (no) | 1999-05-12 |
| KR20000036112A (ko) | 2000-06-26 |
| DE69724130D1 (de) | 2003-09-18 |
| ES2205255T3 (es) | 2004-05-01 |
| EP0927179B1 (en) | 2003-08-13 |
| CN1237171A (zh) | 1999-12-01 |
| PL332319A1 (en) | 1999-08-30 |
| CA2264508A1 (en) | 1998-03-19 |
| CA2264508C (en) | 2003-02-18 |
| SK33999A3 (en) | 2000-06-12 |
| HUP0000126A2 (hu) | 2001-04-28 |
| JP2001500509A (ja) | 2001-01-16 |
| WO1998011100A1 (en) | 1998-03-19 |
| ID22002A (id) | 1999-08-19 |
| DE69724130T2 (de) | 2004-06-03 |
| NO991232D0 (no) | 1999-03-12 |
| CN1109685C (zh) | 2003-05-28 |
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