IL128724A - Pharmaceutical compositions containing isovaleric acid derivatives for treating various neurological pathologies - Google Patents
Pharmaceutical compositions containing isovaleric acid derivatives for treating various neurological pathologiesInfo
- Publication number
- IL128724A IL128724A IL12872497A IL12872497A IL128724A IL 128724 A IL128724 A IL 128724A IL 12872497 A IL12872497 A IL 12872497A IL 12872497 A IL12872497 A IL 12872497A IL 128724 A IL128724 A IL 128724A
- Authority
- IL
- Israel
- Prior art keywords
- isovaleric acid
- pharmaceutical compositions
- compositions containing
- acid derivatives
- treating various
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/84—Valerianaceae (Valerian family), e.g. valerian
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P23/00—Anaesthetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Epidemiology (AREA)
- Pain & Pain Management (AREA)
- Anesthesiology (AREA)
- Medical Informatics (AREA)
- Alternative & Traditional Medicine (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Psychology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Steroid Compounds (AREA)
- Saccharide Compounds (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Cephalosporin Compounds (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IL14547397A IL145473A0 (en) | 1996-08-30 | 1997-08-29 | Use of an extract which is a predrug of isovaleric acid for preparing a pharmaceutical composition for treating spasticity and convulsions |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US2505096P | 1996-08-30 | 1996-08-30 | |
| PCT/US1997/015272 WO1998008498A1 (en) | 1996-08-30 | 1997-08-29 | Treatment of spasticity, convulsions by isovaleric acid derivatives cns depressants |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL128724A0 IL128724A0 (en) | 2000-01-31 |
| IL128724A true IL128724A (en) | 2003-05-29 |
Family
ID=21823778
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL12872497A IL128724A (en) | 1996-08-30 | 1997-08-29 | Pharmaceutical compositions containing isovaleric acid derivatives for treating various neurological pathologies |
Country Status (16)
| Country | Link |
|---|---|
| EP (1) | EP0938304B1 (ja) |
| JP (1) | JP2000504035A (ja) |
| KR (1) | KR100594400B1 (ja) |
| CN (2) | CN1152677C (ja) |
| AT (1) | ATE284683T1 (ja) |
| AU (1) | AU728765B2 (ja) |
| BR (1) | BR9713188A (ja) |
| CA (1) | CA2264577A1 (ja) |
| DE (1) | DE69731968T2 (ja) |
| DK (1) | DK0938304T3 (ja) |
| ES (1) | ES2235251T3 (ja) |
| HK (1) | HK1023725A1 (ja) |
| IL (1) | IL128724A (ja) |
| PT (1) | PT938304E (ja) |
| RU (1) | RU2232016C2 (ja) |
| WO (1) | WO1998008498A1 (ja) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6589994B1 (en) * | 1996-08-30 | 2003-07-08 | Nps Pharmaceuticals, Inc. | Treating a variety of pathological conditions, including spasticity and convulsions, by effecting a modulation of CNS activity with isovaleramide, isovaleric acid, or a related compound |
| EP1059930B1 (en) * | 1998-03-04 | 2005-05-11 | Nps Pharmaceuticals, Inc. | Compositions comprising isovaleramide and ibuprofen |
| AU2003204485B2 (en) * | 1998-03-04 | 2006-06-08 | Nps Pharmaceuticals, Inc. | Compositions comprising valerian extracts, isovaleric acid or derivatives thereof with a nsaid |
| EP1576962A1 (en) * | 1998-03-04 | 2005-09-21 | Nps Pharmaceuticals, Inc. | Composition comprising isovaleramide and ibuprofen |
| US6383527B1 (en) * | 1999-03-04 | 2002-05-07 | Nps Pharmaceuticals, Inc. | Compositions comprising valerian extracts, isovaleric acid or derivatives thereof with a NSAID |
| US6346283B1 (en) * | 1999-03-26 | 2002-02-12 | Ancile Pharmaceuticals | Use of valeriana for the treatment of restless leg syndrome and related disorders |
| EP1225888A2 (en) * | 1999-10-19 | 2002-07-31 | Nps Pharmaceuticals, Inc. | Sustained-release formulations for treating cns-mediated disorders |
| US7235258B1 (en) | 1999-10-19 | 2007-06-26 | Nps Pharmaceuticals, Inc. | Sustained-release formulations for treating CNS-mediated disorders |
| SI1311256T1 (sl) * | 2000-08-17 | 2005-12-31 | Teva Pharma | Uporaba derivatov amidov valprojske kisline in amidov 2-valproenske kisline za zdravljenje ali preprecevanje bolecin in/ali glavobolnih motenj |
| EP1385520A4 (en) * | 2001-02-08 | 2007-03-21 | Nps Pharma Inc | METHODS AND COMPOUNDS FOR THE TREATMENT OF NEUROLOGICAL AND NEUROPSYCHIATRICAL DISEASES AND FOR THE IDENTIFICATION OF COMPOUNDS FOR THE TREATMENT THEREOF |
| WO2003063605A1 (en) * | 2002-02-01 | 2003-08-07 | Eugene Science Inc. | Chewing gum composition containing plant sterol for decrease of flood cholesterol levels and prevention of periodontal disease |
| WO2006012603A2 (en) * | 2004-07-22 | 2006-02-02 | Nps Pharmaceuticals, Inc. | Analogs of isovaleramide, a pharmaceutical composition including the same, and a method of treating central nervous system conditions or diseases |
| DE102006062264A1 (de) * | 2006-12-22 | 2008-06-26 | Joh. Barth & Sohn Gmbh & Co. Kg | Verwendung von Xanthohumol zur Vorbeugung und/oder Bekämpfung von Lebererkrankungen |
| RU2460534C1 (ru) * | 2011-04-15 | 2012-09-10 | Учреждение Российская академия наук Сибирское отделение (СО РАН) Институт общей и экспериментальной биологии (ИОЭБ СО РАН) | Способ получения средства, обладающего анксиолитической активностью |
| CN103565959B (zh) * | 2013-11-06 | 2015-04-08 | 李传平 | 一种治疗精神分裂症的汤剂 |
| CN103961341B (zh) * | 2014-05-30 | 2015-12-02 | 杨献华 | 一种治疗偏头痛的药物组合物及其应用 |
| CN109071424B (zh) * | 2016-02-29 | 2022-01-14 | 生物药品解决方案有限公司 | 氨基磺酸酯衍生物化合物、其制备方法及用途 |
| KR102333460B1 (ko) * | 2016-11-15 | 2021-12-15 | 경희대학교 산학협력단 | 쥐오줌풀 추출물을 유효성분으로 포함하는 측두엽 뇌전증 예방 또는 치료용 약학적 조성물 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1617555C3 (de) * | 1966-04-19 | 1974-09-19 | Kali-Chemie Ag, 3000 Hannover | Verfahren zur Isolierung von therapeutisch wertvollen Isovaleriansäureestern aus Valeriana- und Kentranthus-Extrakten |
| DE2230626B2 (de) * | 1972-06-22 | 1978-07-20 | Roland Dr. 7967 Bad Waldsee Schaette | Baldrianpräparat |
| US5506268A (en) * | 1993-06-11 | 1996-04-09 | Nps Pharmaceuticals, Inc. | Use of isovaleramide as a mild anxiolytic and sedative agent |
-
1997
- 1997-08-29 ES ES97941381T patent/ES2235251T3/es not_active Expired - Lifetime
- 1997-08-29 BR BR9713188-1A patent/BR9713188A/pt not_active Application Discontinuation
- 1997-08-29 EP EP97941381A patent/EP0938304B1/en not_active Expired - Lifetime
- 1997-08-29 WO PCT/US1997/015272 patent/WO1998008498A1/en not_active Application Discontinuation
- 1997-08-29 IL IL12872497A patent/IL128724A/xx not_active IP Right Cessation
- 1997-08-29 KR KR1019997001716A patent/KR100594400B1/ko not_active IP Right Cessation
- 1997-08-29 AT AT97941381T patent/ATE284683T1/de not_active IP Right Cessation
- 1997-08-29 DK DK97941381T patent/DK0938304T3/da active
- 1997-08-29 AU AU43302/97A patent/AU728765B2/en not_active Ceased
- 1997-08-29 PT PT97941381T patent/PT938304E/pt unknown
- 1997-08-29 CA CA002264577A patent/CA2264577A1/en not_active Abandoned
- 1997-08-29 CN CNB971992576A patent/CN1152677C/zh not_active Expired - Fee Related
- 1997-08-29 RU RU99106406/14A patent/RU2232016C2/ru not_active IP Right Cessation
- 1997-08-29 DE DE69731968T patent/DE69731968T2/de not_active Expired - Fee Related
- 1997-08-29 JP JP10511976A patent/JP2000504035A/ja not_active Ceased
- 1997-08-29 CN CNA2004100342927A patent/CN1531924A/zh active Pending
-
2000
- 2000-05-16 HK HK00102920A patent/HK1023725A1/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| IL128724A0 (en) | 2000-01-31 |
| DK0938304T3 (da) | 2005-03-14 |
| CN1152677C (zh) | 2004-06-09 |
| AU4330297A (en) | 1998-03-19 |
| KR20000038194A (ko) | 2000-07-05 |
| AU728765B2 (en) | 2001-01-18 |
| HK1023725A1 (en) | 2000-09-22 |
| DE69731968D1 (de) | 2005-01-20 |
| CN1235541A (zh) | 1999-11-17 |
| ATE284683T1 (de) | 2005-01-15 |
| BR9713188A (pt) | 1999-11-03 |
| RU2232016C2 (ru) | 2004-07-10 |
| WO1998008498A1 (en) | 1998-03-05 |
| ES2235251T3 (es) | 2005-07-01 |
| PT938304E (pt) | 2005-04-29 |
| CN1531924A (zh) | 2004-09-29 |
| KR100594400B1 (ko) | 2006-07-03 |
| EP0938304B1 (en) | 2004-12-15 |
| CA2264577A1 (en) | 1998-03-05 |
| EP0938304A1 (en) | 1999-09-01 |
| JP2000504035A (ja) | 2000-04-04 |
| DE69731968T2 (de) | 2005-12-22 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FF | Patent granted | ||
| KB | Patent renewed | ||
| KB | Patent renewed | ||
| MM9K | Patent not in force due to non-payment of renewal fees |