IL127581A - The crystalline form I of clarithromycin, its preparation, and the pharmaceutical compositions containing it - Google Patents

The crystalline form I of clarithromycin, its preparation, and the pharmaceutical compositions containing it

Info

Publication number
IL127581A
IL127581A IL12758197A IL12758197A IL127581A IL 127581 A IL127581 A IL 127581A IL 12758197 A IL12758197 A IL 12758197A IL 12758197 A IL12758197 A IL 12758197A IL 127581 A IL127581 A IL 127581A
Authority
IL
Israel
Prior art keywords
methylerythromycin
substantially free
preparation
peaks
powder
Prior art date
Application number
IL12758197A
Other languages
English (en)
Hebrew (he)
Other versions
IL127581A0 (en
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=24736505&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IL127581(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Abbott Lab filed Critical Abbott Lab
Publication of IL127581A0 publication Critical patent/IL127581A0/xx
Publication of IL127581A publication Critical patent/IL127581A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
IL12758197A 1996-07-29 1997-07-25 The crystalline form I of clarithromycin, its preparation, and the pharmaceutical compositions containing it IL127581A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/681,723 US5858986A (en) 1996-07-29 1996-07-29 Crystal form I of clarithromycin
PCT/US1997/013128 WO1998004573A1 (en) 1996-07-29 1997-07-25 Crystal form i of clarithromycin

Publications (2)

Publication Number Publication Date
IL127581A0 IL127581A0 (en) 1999-10-28
IL127581A true IL127581A (en) 2004-06-20

Family

ID=24736505

Family Applications (1)

Application Number Title Priority Date Filing Date
IL12758197A IL127581A (en) 1996-07-29 1997-07-25 The crystalline form I of clarithromycin, its preparation, and the pharmaceutical compositions containing it

Country Status (18)

Country Link
US (1) US5858986A (cs)
EP (1) EP0915898B1 (cs)
JP (2) JP2000515894A (cs)
KR (1) KR100498800B1 (cs)
CN (2) CN1754884A (cs)
AT (1) ATE255589T1 (cs)
AU (1) AU3739797A (cs)
BR (1) BR9710768A (cs)
CA (2) CA2627035A1 (cs)
CZ (1) CZ294446B6 (cs)
DE (1) DE69726577T2 (cs)
DK (1) DK0915898T3 (cs)
ES (1) ES2173056T3 (cs)
IL (1) IL127581A (cs)
NZ (1) NZ333380A (cs)
PT (1) PT915898E (cs)
TR (1) TR199900083T2 (cs)
WO (1) WO1998004573A1 (cs)

Families Citing this family (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5945405A (en) * 1997-01-17 1999-08-31 Abbott Laboratories Crystal form O of clarithromycin
KR100377159B1 (ko) * 1998-09-09 2003-08-19 한미약품공업 주식회사 잔류 용매가 없는 클라리스로마이신의 결정형 2의 제조 방법
GB9827355D0 (en) * 1998-12-11 1999-02-03 Biochemie Sa Organic compounds
AU4942800A (en) * 1999-06-11 2001-01-02 Ranbaxy Laboratories Limited Novel amorphous form of clarithromycin
KR100336447B1 (ko) * 1999-11-24 2002-05-15 민경윤 클라리스로마이신의 개선된 제조방법
US6627743B1 (en) 1999-12-03 2003-09-30 Abbott Laboratories 6-O-methylerythromycin A crystal form III
HUP0204091A3 (en) 1999-12-16 2003-05-28 Teva Pharma Processes for preparing clarithromycin polymorphs and novel polymorph iv and pharmaceutical composition containing them and their use
EP1280535B1 (en) * 2000-01-11 2005-02-09 Teva Pharmaceutical Industries Ltd. Processes for preparing clarithromycin polymorphs
US6544555B2 (en) 2000-02-24 2003-04-08 Advancis Pharmaceutical Corp. Antibiotic product, use and formulation thereof
US6565882B2 (en) * 2000-02-24 2003-05-20 Advancis Pharmaceutical Corp Antibiotic composition with inhibitor
US6617436B2 (en) 2000-02-29 2003-09-09 Teva Pharmaceutical Industries Ltd. Processes for preparing clarithromycin and clarithromycin intermediate, essentially oxime-free clarithromycin, and pharmaceutical composition comprising the same
ES2242668T3 (es) * 2000-03-15 2005-11-16 Hanmi Pharm. Co., Ltd. Metodo para obtener claritromicina en cristales de forma ii.
NZ521368A (en) * 2000-03-28 2004-05-28 Biochemie Ges M Granulated particles of an active compound, with a film-forming coating resulting in the masked taste of said active compound
KR20000037126A (ko) * 2000-04-08 2000-07-05 김용규 6-메틸 에리스로마이신 ａ의 제조방법
US6541014B2 (en) * 2000-10-13 2003-04-01 Advancis Pharmaceutical Corp. Antiviral product, use and formulation thereof
US20020068078A1 (en) * 2000-10-13 2002-06-06 Rudnic Edward M. Antifungal product, use and formulation thereof
MXPA03003146A (es) * 2000-10-13 2004-12-06 Advancis Pharmaceuticals Derivados de eritromicina de liberacion prolongada.
US20020197314A1 (en) * 2001-02-23 2002-12-26 Rudnic Edward M. Anti-fungal composition
KR100408848B1 (ko) * 2001-03-12 2003-12-06 주식회사 씨트리 클래리스로마이신의 정제방법
CN100427498C (zh) * 2003-03-02 2008-10-22 王凌峰 克拉霉素a型结晶
AU2004258949B2 (en) * 2003-07-21 2011-02-10 Shionogi, Inc. Antibiotic product, use and formulation thereof
JP2006528185A (ja) * 2003-07-21 2006-12-14 アドバンシス ファーマスーティカル コーポレイション 抗生物質製剤、その使用法及び作成方法
WO2005009368A2 (en) * 2003-07-21 2005-02-03 Advancis Pharmaceutical Corporation Antibiotic product, use and formulation thereof
WO2005016311A1 (en) * 2003-08-11 2005-02-24 Advancis Pharmaceutical Corporation Robust pellet
WO2005016278A2 (en) 2003-08-12 2005-02-24 Advancis Pharmaceuticals Corporation Antibiotic product, use and formulation thereof
JP5686494B2 (ja) * 2003-08-29 2015-03-18 シオノギ インコーポレイテッド 抗生物質製剤、その使用法及び作成方法
AU2004273830B2 (en) * 2003-09-15 2011-03-24 Shionogi, Inc. Antibiotic product, use and formulation thereof
WO2005061524A2 (en) * 2003-12-22 2005-07-07 Ranbaxy Laboratories Limited Process for the preparation of form ii clarithromycin
JP2007517039A (ja) * 2003-12-24 2007-06-28 アドバンシス ファーマスーティカル コーポレイション 変性放出製剤の吸収増強
EP1771158A4 (en) * 2004-07-02 2008-03-12 Advancis Pharmaceutical Corp TABLET FOR PULSE DISTRIBUTION
US20060111560A1 (en) * 2004-11-01 2006-05-25 Glenmark Pharmaceuticals Limited Process for the preparation of crystalline form II of clarithromycin
JP2009500356A (ja) * 2005-07-07 2009-01-08 エラン ファーマ インターナショナル リミテッド ナノ粒子クラリスロマイシン製剤
WO2007036951A2 (en) * 2005-08-31 2007-04-05 Alembic Limited Process to obtain 6-o-methylerythromycin a (clarithromycin)_form ii
US8357394B2 (en) 2005-12-08 2013-01-22 Shionogi Inc. Compositions and methods for improved efficacy of penicillin-type antibiotics
US8778924B2 (en) * 2006-12-04 2014-07-15 Shionogi Inc. Modified release amoxicillin products
US8299052B2 (en) 2006-05-05 2012-10-30 Shionogi Inc. Pharmaceutical compositions and methods for improved bacterial eradication
DE102007016367A1 (de) 2007-04-03 2008-10-09 Grünenthal GmbH Polymorph von Clarithromycin (Form V)
WO2009023191A2 (en) * 2007-08-09 2009-02-19 Teva Pharmaceutical Industries Ltd. An improved process for the preparation of clarithromycin
EP2030613A1 (en) 2007-08-17 2009-03-04 Abbott GmbH & Co. KG Preparation of compositions with essentially noncrystalline embedded macrolide antibiotics
CN101525360B (zh) * 2008-03-06 2012-10-10 刘力 大环内酯类有机酸盐的水合物及其制备和用途
CN101812102B (zh) * 2009-02-21 2015-09-02 王凌峰 6-o-甲基红霉素a晶型v
CN102532222B (zh) * 2010-12-21 2015-06-17 北大方正集团有限公司 一种麦迪霉素的结晶方法
US9119769B2 (en) 2011-12-30 2015-09-01 The Curators Of The University Of Missouri Method for transforming pharmaceutical crystal forms
CN102942607A (zh) * 2012-11-28 2013-02-27 宁夏启元药业有限公司 一种复合溶剂结晶红霉素的方法

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5782400A (en) 1980-11-12 1982-05-22 Taisho Pharmaceut Co Ltd Erythromycin derivative
US4331803A (en) 1980-06-04 1982-05-25 Taisho Pharmaceutical Co., Ltd. Novel erythromycin compounds
JPS60214796A (ja) * 1984-04-06 1985-10-28 Taisho Pharmaceut Co Ltd ６−０−メチルエリスロマイシン類の製法
JPS61103890A (ja) 1984-10-26 1986-05-22 Taisho Pharmaceut Co Ltd ６−０−メチルエリスロマイシンａ誘導体
US4670549A (en) * 1985-03-18 1987-06-02 Taisho Pharmaceutical Co., Ltd. Method for selective methylation of erythromycin a derivatives
DE3782994T2 (de) 1986-09-18 1993-04-08 Taisho Pharma Co Ltd Erythromycin-a-derivate und verfahren zu ihrer herstellung.
JPH0755958B2 (ja) * 1986-10-03 1995-06-14 大正製薬株式会社 エリスロマイシンａ誘導体の製造方法
JP2526951B2 (ja) * 1986-12-17 1996-08-21 大正製薬株式会社 エリスロマイシンａ誘導体およびその製造方法
KR960000434B1 (ko) 1986-12-17 1996-01-06 다이쇼 세이야꾸 가부시끼가이샤 에리스로마이신 a유도체 및 그의 제조 방법
JP2782793B2 (ja) * 1988-06-15 1998-08-06 大正製薬株式会社 エリスロマイシンａ誘導体およびその製造方法
US5872229A (en) * 1995-11-21 1999-02-16 Abbott Laboratories Process for 6-O-alkylation of erythromycin derivatives
US5837829A (en) 1996-04-02 1998-11-17 Abbott Laboratories 9-oximesilyl erythromycin a derivatives
US5719272A (en) 1996-04-02 1998-02-17 Abbott Laboratories 2'-protected 3'-dimethylamine, 9-etheroxime erythromycin A derivatives

Also Published As

Publication number Publication date
KR100498800B1 (ko) 2005-07-01
DK0915898T3 (da) 2004-02-16
WO1998004573A1 (en) 1998-02-05
JP2000515894A (ja) 2000-11-28
ES2173056T3 (es) 2004-06-16
ATE255589T1 (de) 2003-12-15
BR9710768A (pt) 1999-08-17
NZ333380A (en) 2000-01-28
EP0915898A1 (en) 1999-05-19
EP0915898B1 (en) 2003-12-03
TR199900083T2 (xx) 1999-04-21
CN1229411A (zh) 1999-09-22
CA2627035A1 (en) 1998-02-05
DE69726577T2 (de) 2004-11-04
JP5290136B2 (ja) 2013-09-18
CN1216892C (zh) 2005-08-31
KR20000029644A (ko) 2000-05-25
AU3739797A (en) 1998-02-20
DE69726577D1 (en) 2004-01-15
JP2010090156A (ja) 2010-04-22
IL127581A0 (en) 1999-10-28
CZ9999A3 (cs) 1999-05-12
CA2258606C (en) 2003-05-27
ES2173056T1 (es) 2002-10-16
PT915898E (pt) 2004-02-27
US5858986A (en) 1999-01-12
CN1754884A (zh) 2006-04-05
CZ294446B6 (cs) 2005-01-12
CA2258606A1 (en) 1998-02-05

Similar Documents

Publication Publication Date Title
US5858986A (en) Crystal form I of clarithromycin
US5844105A (en) Preparation of crystal form II of clarithromycin
AU2001222619C1 (en) Processes for preparing clarithromycin polymorphs
AU733646B2 (en) Preparation of crystal form II of clarithromycin
AU783055B2 (en) Processes for preparing clarithromycin polymorphs and novel polymorph IV
CA2309963C (en) 6-o-alkyl erythromycin b oxime
CA2386527C (en) Crystal form i of clarithromycin
AU777612B2 (en) Crystal form I of clarithromycin
CA2488397C (en) Crystal form ii of clarithromycin
CA2386534C (en) Crystal form ii of clarithromycin and uses thereof
HK1089182A (en) Crystal form i of clarithromycin
AU2005203314A1 (en) Processes for preparing clarithromycin polymorphs
ZA200204638B (en) Processes for preparing clarithromycin polymorphs and novel polymorph IV.

Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
KB Patent renewed
KB Patent renewed
EXP Patent expired