IL126725A0 - Compositions comprising a nitrone compound for use in treating ocular inflammation - Google Patents
Compositions comprising a nitrone compound for use in treating ocular inflammationInfo
- Publication number
- IL126725A0 IL126725A0 IL12672597A IL12672597A IL126725A0 IL 126725 A0 IL126725 A0 IL 126725A0 IL 12672597 A IL12672597 A IL 12672597A IL 12672597 A IL12672597 A IL 12672597A IL 126725 A0 IL126725 A0 IL 126725A0
- Authority
- IL
- Israel
- Prior art keywords
- compositions
- ocular inflammation
- nitrone compound
- treating ocular
- inflammation
- Prior art date
Links
- 206010061218 Inflammation Diseases 0.000 title abstract 3
- 230000004054 inflammatory process Effects 0.000 title abstract 2
- -1 nitrone compound Chemical class 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 2
- 206010046851 Uveitis Diseases 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/89—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to the ring nitrogen atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/4015—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil having oxo groups directly attached to the heterocyclic ring, e.g. piracetam, ethosuximide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4412—Non condensed pyridines; Hydrogenated derivatives thereof having oxo groups directly attached to the heterocyclic ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/14—Decongestants or antiallergics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C291/00—Compounds containing carbon and nitrogen and having functional groups not covered by groups C07C201/00 - C07C281/00
- C07C291/02—Compounds containing carbon and nitrogen and having functional groups not covered by groups C07C201/00 - C07C281/00 containing nitrogen-oxide bonds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/22—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with hetero atoms directly attached to ring nitrogen atoms
- C07D295/24—Oxygen atoms
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Ophthalmology & Optometry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pyrrole Compounds (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US1627696P | 1996-04-23 | 1996-04-23 | |
| PCT/US1997/006604 WO1997039751A1 (en) | 1996-04-23 | 1997-04-23 | Compositions comprising a nitrone compound for use in treating ocular inflammation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL126725A0 true IL126725A0 (en) | 1999-08-17 |
Family
ID=21776304
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL12672597A IL126725A0 (en) | 1996-04-23 | 1997-04-23 | Compositions comprising a nitrone compound for use in treating ocular inflammation |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US5972977A (no) |
| EP (1) | EP0910370B1 (no) |
| JP (1) | JP2000509375A (no) |
| CN (1) | CN1219130A (no) |
| AT (1) | ATE263559T1 (no) |
| AU (1) | AU721531B2 (no) |
| CA (1) | CA2252494A1 (no) |
| DE (1) | DE69728536T2 (no) |
| IL (1) | IL126725A0 (no) |
| NO (1) | NO984920L (no) |
| NZ (1) | NZ332561A (no) |
| TW (1) | TW450952B (no) |
| WO (1) | WO1997039751A1 (no) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050107366A1 (en) * | 1991-06-18 | 2005-05-19 | Carney John M. | Spin trapping pharmaceutical compositions and methods for use thereof |
| JP2002506022A (ja) * | 1998-03-13 | 2002-02-26 | センター ファーマシューティカルズ， インコーポレイテッド | 新脈管形成の阻害 |
| US6083989A (en) | 1999-05-18 | 2000-07-04 | Centaur Pharmaceuticals, Inc. | Aryl nitrone therapeutics for the treatment of inflammatory bowel disease |
| EP1079820A1 (en) | 1998-05-19 | 2001-03-07 | Centaur Pharmaceuticals, Inc. | Benzamide therapeutics for the treatment of inflammatory bowel disease |
| SI1077694T1 (en) * | 1998-05-19 | 2004-10-31 | Renovis, Inc. | Aryl nitrone therapeutics for the treatment of inflammatory bowel disease |
| AU750599B2 (en) * | 1998-07-17 | 2002-07-25 | Renovis, Inc. | Alpha-(2-hydroxyphenyl) nitrone compounds, pharmaceutical compositions containing the same and their use for treating inflammation |
| US6730700B2 (en) | 1998-12-02 | 2004-05-04 | Renovis, Inc. | 3,4,5,-trisubstituted aryl nitrone compounds and pharmaceutical compositions containing the same |
| UA66401C2 (en) * | 1998-12-02 | 2004-05-17 | Sentor Pharmaceuticals Inc | 3,4,5-trisubstituted aryl nitrone compounds and pharmaceutical composition containing the same |
| AU5601300A (en) * | 1999-06-09 | 2000-12-28 | Department Of The Army, U.S. Government | Method and compositions for treating and preventing retinal damage |
| US20050059638A1 (en) * | 2003-08-04 | 2005-03-17 | Kelly Michael G. | Aryl, heteroaromatic and bicyclic aryl nitrone compounds, prodrugs and pharmaceutical compositions of the same to treat human disorders |
| US20050182060A1 (en) * | 2004-02-13 | 2005-08-18 | Kelly Michael G. | 2-Substituted and 4-substituted aryl nitrone compounds |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4153722A (en) * | 1977-10-06 | 1979-05-08 | William H. Rorer, Inc. | Method of treatment |
| US5025032A (en) * | 1989-10-17 | 1991-06-18 | Oklahoma Medical Research Foundation | Phenyl butyl nitrone compositions and methods for treatment of oxidative tissue damage |
| US5036097A (en) * | 1989-10-17 | 1991-07-30 | Oklahoma Medical Research Foundation | Phenylbutyl nitrone compositions and methods for prevention of gastric ulceration |
| ATE110565T1 (de) * | 1989-10-17 | 1994-09-15 | Oklahoma Med Res Found | Verfahren und zubereitungen zur hemmung von mit oxidativer schädigung assoziierten krankheiten. |
| CA2111836C (en) * | 1991-06-18 | 2006-08-29 | John M. Carney | Spin-trapping pharmaceutical compositions and methods for use thereof |
| US5455272A (en) * | 1993-10-22 | 1995-10-03 | Oklahoma Medical Research Foundation | Spin trap nitronyl hindered phenols |
-
1997
- 1997-04-23 TW TW086105289A patent/TW450952B/zh not_active IP Right Cessation
- 1997-04-23 DE DE69728536T patent/DE69728536T2/de not_active Expired - Fee Related
- 1997-04-23 EP EP97921289A patent/EP0910370B1/en not_active Expired - Lifetime
- 1997-04-23 CA CA002252494A patent/CA2252494A1/en not_active Abandoned
- 1997-04-23 US US08/847,386 patent/US5972977A/en not_active Expired - Fee Related
- 1997-04-23 AU AU27366/97A patent/AU721531B2/en not_active Ceased
- 1997-04-23 IL IL12672597A patent/IL126725A0/xx unknown
- 1997-04-23 NZ NZ332561A patent/NZ332561A/en unknown
- 1997-04-23 CN CN97194855A patent/CN1219130A/zh active Pending
- 1997-04-23 JP JP9538232A patent/JP2000509375A/ja not_active Ceased
- 1997-04-23 AT AT97921289T patent/ATE263559T1/de not_active IP Right Cessation
- 1997-04-23 WO PCT/US1997/006604 patent/WO1997039751A1/en active IP Right Grant
-
1998
- 1998-10-22 NO NO984920A patent/NO984920L/no not_active Application Discontinuation
-
1999
- 1999-09-20 US US09/399,733 patent/US6140356A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| DE69728536D1 (de) | 2004-05-13 |
| NO984920L (no) | 1998-12-23 |
| EP0910370A1 (en) | 1999-04-28 |
| EP0910370B1 (en) | 2004-04-07 |
| CN1219130A (zh) | 1999-06-09 |
| US5972977A (en) | 1999-10-26 |
| ATE263559T1 (de) | 2004-04-15 |
| AU2736697A (en) | 1997-11-12 |
| DE69728536T2 (de) | 2005-02-24 |
| TW450952B (en) | 2001-08-21 |
| NZ332561A (en) | 2001-01-26 |
| US6140356A (en) | 2000-10-31 |
| JP2000509375A (ja) | 2000-07-25 |
| AU721531B2 (en) | 2000-07-06 |
| NO984920D0 (no) | 1998-10-22 |
| CA2252494A1 (en) | 1997-10-30 |
| WO1997039751A1 (en) | 1997-10-30 |
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