IL125960A0 - Novel sulphur derivatives comprising an amide bond method for preparing same use thereof as drugs and pharmaceutical compositions containing such derivatives - Google Patents

Novel sulphur derivatives comprising an amide bond method for preparing same use thereof as drugs and pharmaceutical compositions containing such derivatives

Info

Publication number
IL125960A0
IL125960A0 IL12596097A IL12596097A IL125960A0 IL 125960 A0 IL125960 A0 IL 125960A0 IL 12596097 A IL12596097 A IL 12596097A IL 12596097 A IL12596097 A IL 12596097A IL 125960 A0 IL125960 A0 IL 125960A0
Authority
IL
Israel
Prior art keywords
derivatives
drugs
pharmaceutical compositions
compositions containing
amide bond
Prior art date
Application number
IL12596097A
Other languages
English (en)
Original Assignee
Hoechst Marion Roussel Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Marion Roussel Inc filed Critical Hoechst Marion Roussel Inc
Publication of IL125960A0 publication Critical patent/IL125960A0/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D257/00Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D257/04Five-membered rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/50Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
    • C07C323/51Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C323/60Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton with the carbon atom of at least one of the carboxyl groups bound to nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/10Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/24Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IL12596097A 1996-03-04 1997-03-03 Novel sulphur derivatives comprising an amide bond method for preparing same use thereof as drugs and pharmaceutical compositions containing such derivatives IL125960A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9602672A FR2745571B1 (fr) 1996-03-04 1996-03-04 Nouveaux derives soufres comportant une liaison amide, leur procede de preparation, leur application a titre de medicaments, et les compositions pharmaceutiques les renfermant
PCT/FR1997/000367 WO1997032874A1 (fr) 1996-03-04 1997-03-03 Nouveaux derives soufres comportant une liaison amide, leur procede de preparation, leur application a titre de medicaments et les compositions pharmaceutiques les renfermant

Publications (1)

Publication Number Publication Date
IL125960A0 true IL125960A0 (en) 1999-04-11

Family

ID=9489805

Family Applications (1)

Application Number Title Priority Date Filing Date
IL12596097A IL125960A0 (en) 1996-03-04 1997-03-03 Novel sulphur derivatives comprising an amide bond method for preparing same use thereof as drugs and pharmaceutical compositions containing such derivatives

Country Status (19)

Country Link
US (1) US6136842A (xx)
EP (1) EP0888341B1 (xx)
JP (1) JP2000507220A (xx)
KR (1) KR19990087484A (xx)
CN (1) CN1218467A (xx)
AT (1) ATE311384T1 (xx)
AU (1) AU724686B2 (xx)
BR (1) BR9707931A (xx)
CA (1) CA2248187A1 (xx)
DE (1) DE69734764T2 (xx)
DK (1) DK0888341T3 (xx)
ES (1) ES2253771T3 (xx)
FR (1) FR2745571B1 (xx)
IL (1) IL125960A0 (xx)
NO (1) NO984047L (xx)
PL (1) PL328699A1 (xx)
RU (1) RU2203661C2 (xx)
TR (1) TR199801756T2 (xx)
WO (1) WO1997032874A1 (xx)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY153569A (en) * 1998-01-20 2015-02-27 Mitsubishi Tanabe Pharma Corp Inhibitors of ?4 mediated cell adhesion
US6423727B1 (en) 1998-04-23 2002-07-23 Novartis Ag Certain thiol inhibitors of endothelin-converting enzyme
US6426354B1 (en) 1998-04-23 2002-07-30 Novartis Ag Certain heteroaryl substituted thiol inhibitors of endothelin-converting enzyme
AU750048B2 (en) * 1998-04-23 2002-07-11 Novartis Ag Certain heteroaryl substituted thiol inhibitors of endothelin-converting enzyme
EP1073674A1 (en) * 1998-04-23 2001-02-07 Novartis AG Thiol inhibitors of endothelin-converting enzyme
FR2805259B1 (fr) * 2000-02-17 2002-03-29 Inst Nat Sante Rech Med Nouveaux derives d'aminoacides n-mercaptoacyles, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
FR2823212B1 (fr) * 2001-04-10 2005-12-02 Inst Nat Sante Rech Med Inhibiteurs de la toxine botulique de type b
DE10147672A1 (de) * 2001-09-27 2003-04-10 Bayer Ag Substituierte 2,5-Diamidoindole und ihre Verwendung
US7345068B2 (en) * 2002-02-07 2008-03-18 Hitoshi Endou Aromatic amino acid derivatives and medicinal compositions
MY140707A (en) 2002-02-28 2010-01-15 Mitsubishi Tanabe Pharma Corp Process for preparing a phenylalanine derivative and intermediates thereof
CA2510811A1 (en) * 2002-12-20 2004-07-08 Bayer Healthcare Ag Use of substituted 2,5-diamidoindoles for the treatment of urological diseases
FR2931151A1 (fr) * 2008-05-13 2009-11-20 Pharmaleads Soc Par Actions Si Nouveaux derives d'amino-acides, leur procede de preparation et leur utilisation therapeutique

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1009252A (en) * 1972-10-03 1977-04-26 Santen Pharmaceutical Co. N-(mercaptoacyl) aminoacids
US4053651A (en) * 1976-05-10 1977-10-11 E. R. Squibb & Sons, Inc. Compounds and method for alleviating angiotensin related hypertension
GB2092574A (en) * 1981-02-10 1982-08-18 Ici Plc Amide derivatives
US5262436A (en) * 1987-03-27 1993-11-16 Schering Corporation Acylamino acid antihypertensives in the treatment of congestive heart failure
CA1337400C (en) * 1987-06-08 1995-10-24 Norma G. Delaney Inhibitors of neutral endopeptidase
US5599951A (en) * 1989-09-15 1997-02-04 Societe Civile Bioprojet Amino acid derivatives, the process for their preparation and their applications to therapy

Also Published As

Publication number Publication date
AU1930697A (en) 1997-09-22
DE69734764T2 (de) 2006-09-21
WO1997032874A1 (fr) 1997-09-12
FR2745571A1 (fr) 1997-09-05
EP0888341A1 (fr) 1999-01-07
KR19990087484A (ko) 1999-12-27
RU2203661C2 (ru) 2003-05-10
US6136842A (en) 2000-10-24
DK0888341T3 (da) 2006-04-10
EP0888341B1 (fr) 2005-11-30
NO984047D0 (no) 1998-09-03
JP2000507220A (ja) 2000-06-13
ATE311384T1 (de) 2005-12-15
ES2253771T3 (es) 2006-06-01
BR9707931A (pt) 1999-07-27
DE69734764D1 (de) 2006-01-05
CA2248187A1 (fr) 1997-09-12
FR2745571B1 (fr) 1998-06-19
NO984047L (no) 1998-11-03
PL328699A1 (en) 1999-02-15
AU724686B2 (en) 2000-09-28
TR199801756T2 (xx) 1998-12-21
CN1218467A (zh) 1999-06-02

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