IL125049A - Method for selective protection of baccatin derivatives and its application to taxane synthesis - Google Patents

Method for selective protection of baccatin derivatives and its application to taxane synthesis

Info

Publication number
IL125049A
IL125049A IL12504996A IL12504996A IL125049A IL 125049 A IL125049 A IL 125049A IL 12504996 A IL12504996 A IL 12504996A IL 12504996 A IL12504996 A IL 12504996A IL 125049 A IL125049 A IL 125049A
Authority
IL
Israel
Prior art keywords
application
selective protection
baccatin derivatives
taxane synthesis
derivatives
Prior art date
Application number
IL12504996A
Other languages
English (en)
Other versions
IL125049A0 (en
Original Assignee
Rech N En Ingenierie Pharma Se
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rech N En Ingenierie Pharma Se filed Critical Rech N En Ingenierie Pharma Se
Priority to IL13876896A priority Critical patent/IL138768A/xx
Priority to IL13876996A priority patent/IL138769A0/xx
Publication of IL125049A0 publication Critical patent/IL125049A0/xx
Publication of IL125049A publication Critical patent/IL125049A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02Silicon compounds
    • C07F7/08Compounds having one or more C—Si linkages
    • C07F7/18Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804Compounds having Si-O-C linkages
    • C07F7/1872Preparation; Treatments not provided for in C07F7/20
    • C07F7/188Preparation; Treatments not provided for in C07F7/20 by reactions involving the formation of Si-O linkages
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D305/00Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02Silicon compounds
    • C07F7/08Compounds having one or more C—Si linkages
    • C07F7/18Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804Compounds having Si-O-C linkages

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epoxy Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
IL12504996A 1995-12-27 1996-12-27 Method for selective protection of baccatin derivatives and its application to taxane synthesis IL125049A (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
IL13876896A IL138768A (en) 1995-12-27 1996-12-27 Taxane derivatives and processes for their preparation
IL13876996A IL138769A0 (en) 1995-12-27 1996-12-27 Taxane derivatives and processes for their preparation

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9515557A FR2743074B1 (fr) 1995-12-27 1995-12-27 Procede de protection selective des derives de la baccatine et son utilisation dans la synthese des taxanes
PCT/FR1996/002097 WO1997024345A1 (fr) 1995-12-27 1996-12-27 Procede de protection selective des derives de la baccatine et son utilisation dans la synthese des taxanes

Publications (2)

Publication Number Publication Date
IL125049A0 IL125049A0 (en) 1999-01-26
IL125049A true IL125049A (en) 2003-10-31

Family

ID=9486008

Family Applications (2)

Application Number Title Priority Date Filing Date
IL12504996A IL125049A (en) 1995-12-27 1996-12-27 Method for selective protection of baccatin derivatives and its application to taxane synthesis
IL138769A IL138769A (en) 1995-12-27 2000-09-28 Texan derivatives and processes for their preparation

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL138769A IL138769A (en) 1995-12-27 2000-09-28 Texan derivatives and processes for their preparation

Country Status (25)

Country Link
US (1) US6180802B1 (es)
EP (1) EP0889885B1 (es)
JP (1) JP4068663B2 (es)
KR (1) KR100510017B1 (es)
CN (3) CN1090625C (es)
AT (1) ATE218133T1 (es)
AU (1) AU716876B2 (es)
BR (1) BR9612242A (es)
CA (1) CA2238889C (es)
CZ (1) CZ20191998A3 (es)
DE (1) DE69621463T2 (es)
DK (1) DK0889885T3 (es)
ES (1) ES2177825T3 (es)
FR (1) FR2743074B1 (es)
HK (2) HK1044765B (es)
HU (1) HUP0000508A3 (es)
IL (2) IL125049A (es)
NO (1) NO982719D0 (es)
NZ (1) NZ325323A (es)
PL (1) PL327581A1 (es)
PT (1) PT889885E (es)
RU (1) RU2162844C2 (es)
SK (1) SK88498A3 (es)
TR (1) TR199801232T2 (es)
WO (1) WO1997024345A1 (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0875508B1 (en) * 1997-05-02 2003-10-22 Pharmachemie B.V. Method for the preparation of baccatin III and derivatives thereof from 10-deacetylbaccatin III
US7288665B1 (en) * 1997-08-18 2007-10-30 Florida State University Process for selective derivatization of taxanes
JP5498168B2 (ja) 2006-12-01 2014-05-21 ブリストル−マイヤーズ スクイブ カンパニー アテローム性動脈硬化および循環器疾患の治療のためのcetp阻害剤としてのn−((3−ベンジル)−2,2−(ビス−フェニル)−プロパン−1−アミン誘導体
EP2183234A4 (en) * 2007-08-22 2012-02-29 Canada Inc 6570763 PROCESS FOR CONVERTING 9-DIHYDRO-13-ACETYLBACCATIN III IN DOCETAXEL OR PACLITAXEL
PL388144A1 (pl) 2009-05-29 2010-12-06 Przedsiębiorstwo Produkcyjno-Wdrożeniowe Ifotam Spółka Z Ograniczoną Odpowiedzialnością Solwaty (2R,3S)-3-tert-butoksykarbonylamino-2-hydroksy-3-fenylopropionianu 4-acetoksy-2α-benzoiloksy -5β,20-epoksy-1,7β,10β-trihydroksy-9-okso-taks-11-en-13α-ylu, sposób ich otrzymywania i zastosowanie
CN115260130A (zh) * 2022-07-07 2022-11-01 上海卓鼎生物技术有限公司 一种10-脱乙酰基紫杉醇的制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2601675B1 (fr) * 1986-07-17 1988-09-23 Rhone Poulenc Sante Derives du taxol, leur preparation et les compositions pharmaceutiques qui les contiennent
FR2601676B1 (fr) * 1986-07-17 1988-09-23 Rhone Poulenc Sante Procede de preparation du taxol et du desacetyl-10 taxol
IL127599A (en) * 1994-01-28 2004-06-01 Upjohn Co Process for preparing isotaxol analogs

Also Published As

Publication number Publication date
HUP0000508A3 (en) 2001-05-28
HK1047099A1 (es) 2003-02-07
IL138769A (en) 2006-04-10
ATE218133T1 (de) 2002-06-15
AU716876B2 (en) 2000-03-09
FR2743074A1 (fr) 1997-07-04
FR2743074B1 (fr) 1998-03-27
HK1047099B (zh) 2006-09-29
HK1044765B (zh) 2006-09-29
CN1090625C (zh) 2002-09-11
CN1206412A (zh) 1999-01-27
NO982719L (no) 1998-06-12
KR19990076733A (ko) 1999-10-15
JP2000502696A (ja) 2000-03-07
CZ20191998A3 (cs) 1998-09-16
DK0889885T3 (da) 2002-09-16
SK88498A3 (en) 1998-11-04
TR199801232T2 (xx) 1998-09-21
EP0889885B1 (fr) 2002-05-29
DE69621463D1 (de) 2002-07-04
DE69621463T2 (de) 2002-11-28
CA2238889A1 (fr) 1997-07-10
RU2162844C2 (ru) 2001-02-10
CN1244567C (zh) 2006-03-08
ES2177825T3 (es) 2002-12-16
CA2238889C (fr) 2008-06-10
PL327581A1 (en) 1998-12-21
CN1356325A (zh) 2002-07-03
HK1044765A1 (en) 2002-11-01
HUP0000508A2 (en) 2000-07-28
NO982719D0 (no) 1998-06-12
PT889885E (pt) 2002-10-31
AU1381597A (en) 1997-07-28
WO1997024345A1 (fr) 1997-07-10
CN1356326A (zh) 2002-07-03
NZ325323A (en) 1999-11-29
KR100510017B1 (ko) 2005-12-16
US6180802B1 (en) 2001-01-30
EP0889885A1 (fr) 1999-01-13
JP4068663B2 (ja) 2008-03-26
BR9612242A (pt) 1999-07-13
IL125049A0 (en) 1999-01-26
CN1243745C (zh) 2006-03-01

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FR2696463B1 (fr) Procédé d'obtention de la désacétyl-10 baccatine III.
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Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees