HUP0000508A3 - Method for selective protection of baccatin derivatives and its application to taxane synthesis - Google Patents

Method for selective protection of baccatin derivatives and its application to taxane synthesis

Info

Publication number
HUP0000508A3
HUP0000508A3 HU0000508A HUP0000508A HUP0000508A3 HU P0000508 A3 HUP0000508 A3 HU P0000508A3 HU 0000508 A HU0000508 A HU 0000508A HU P0000508 A HUP0000508 A HU P0000508A HU P0000508 A3 HUP0000508 A3 HU P0000508A3
Authority
HU
Hungary
Prior art keywords
application
selective protection
baccatin derivatives
taxane synthesis
taxane
Prior art date
Application number
HU0000508A
Other languages
English (en)
Original Assignee
Seripharm
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Seripharm filed Critical Seripharm
Publication of HUP0000508A2 publication Critical patent/HUP0000508A2/hu
Publication of HUP0000508A3 publication Critical patent/HUP0000508A3/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages
    • C07F7/1872—Preparation; Treatments not provided for in C07F7/20
    • C07F7/188—Preparation; Treatments not provided for in C07F7/20 by reactions involving the formation of Si-O linkages
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epoxy Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
HU0000508A 1995-12-27 1996-12-27 Method for selective protection of baccatin derivatives and its application to taxane synthesis HUP0000508A3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9515557A FR2743074B1 (fr) 1995-12-27 1995-12-27 Procede de protection selective des derives de la baccatine et son utilisation dans la synthese des taxanes

Publications (2)

Publication Number Publication Date
HUP0000508A2 HUP0000508A2 (en) 2000-07-28
HUP0000508A3 true HUP0000508A3 (en) 2001-05-28

Family

ID=9486008

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0000508A HUP0000508A3 (en) 1995-12-27 1996-12-27 Method for selective protection of baccatin derivatives and its application to taxane synthesis

Country Status (25)

Country Link
US (1) US6180802B1 (hu)
EP (1) EP0889885B1 (hu)
JP (1) JP4068663B2 (hu)
KR (1) KR100510017B1 (hu)
CN (3) CN1244567C (hu)
AT (1) ATE218133T1 (hu)
AU (1) AU716876B2 (hu)
BR (1) BR9612242A (hu)
CA (1) CA2238889C (hu)
CZ (1) CZ20191998A3 (hu)
DE (1) DE69621463T2 (hu)
DK (1) DK0889885T3 (hu)
ES (1) ES2177825T3 (hu)
FR (1) FR2743074B1 (hu)
HK (2) HK1044765B (hu)
HU (1) HUP0000508A3 (hu)
IL (2) IL125049A (hu)
NO (1) NO982719D0 (hu)
NZ (1) NZ325323A (hu)
PL (1) PL327581A1 (hu)
PT (1) PT889885E (hu)
RU (1) RU2162844C2 (hu)
SK (1) SK88498A3 (hu)
TR (1) TR199801232T2 (hu)
WO (1) WO1997024345A1 (hu)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0875508T3 (da) * 1997-05-02 2004-01-26 Pharmachemie Bv Fremgangsmåde til fremstilling af baccatin lll og derivater ud fra 10-deacetylbaccatin lll
US7288665B1 (en) * 1997-08-18 2007-10-30 Florida State University Process for selective derivatization of taxanes
CN101663262B (zh) 2006-12-01 2014-03-26 百时美施贵宝公司 用于治疗动脉粥样硬化和心血管疾病的作为cetp抑制剂的n-(3-苄基)-2,2-(二苯基)-丙-1胺衍生物
AU2008288651A1 (en) * 2007-08-22 2009-02-26 6570763 Canada Inc. Process for converting 9-dihydro-13-acetylbaccatin III into docetaxel or paclitaxel
PL388144A1 (pl) 2009-05-29 2010-12-06 Przedsiębiorstwo Produkcyjno-Wdrożeniowe Ifotam Spółka Z Ograniczoną Odpowiedzialnością Solwaty (2R,3S)-3-tert-butoksykarbonylamino-2-hydroksy-3-fenylopropionianu 4-acetoksy-2α-benzoiloksy -5β,20-epoksy-1,7β,10β-trihydroksy-9-okso-taks-11-en-13α-ylu, sposób ich otrzymywania i zastosowanie
CN115260130A (zh) * 2022-07-07 2022-11-01 上海卓鼎生物技术有限公司 一种10-脱乙酰基紫杉醇的制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2601675B1 (fr) * 1986-07-17 1988-09-23 Rhone Poulenc Sante Derives du taxol, leur preparation et les compositions pharmaceutiques qui les contiennent
FR2601676B1 (fr) 1986-07-17 1988-09-23 Rhone Poulenc Sante Procede de preparation du taxol et du desacetyl-10 taxol
IL127597A (en) 1994-01-28 2003-07-31 Upjohn Co Iso-taxol analogs

Also Published As

Publication number Publication date
NO982719L (no) 1998-06-12
ATE218133T1 (de) 2002-06-15
RU2162844C2 (ru) 2001-02-10
FR2743074A1 (fr) 1997-07-04
NZ325323A (en) 1999-11-29
ES2177825T3 (es) 2002-12-16
EP0889885A1 (fr) 1999-01-13
CN1206412A (zh) 1999-01-27
JP2000502696A (ja) 2000-03-07
EP0889885B1 (fr) 2002-05-29
FR2743074B1 (fr) 1998-03-27
KR19990076733A (ko) 1999-10-15
CN1243745C (zh) 2006-03-01
TR199801232T2 (xx) 1998-09-21
DE69621463T2 (de) 2002-11-28
CN1090625C (zh) 2002-09-11
JP4068663B2 (ja) 2008-03-26
PT889885E (pt) 2002-10-31
AU1381597A (en) 1997-07-28
IL125049A0 (en) 1999-01-26
WO1997024345A1 (fr) 1997-07-10
AU716876B2 (en) 2000-03-09
HK1047099B (zh) 2006-09-29
HK1044765B (zh) 2006-09-29
CA2238889A1 (fr) 1997-07-10
IL125049A (en) 2003-10-31
BR9612242A (pt) 1999-07-13
CZ20191998A3 (cs) 1998-09-16
CA2238889C (fr) 2008-06-10
HK1044765A1 (en) 2002-11-01
HUP0000508A2 (en) 2000-07-28
NO982719D0 (no) 1998-06-12
CN1244567C (zh) 2006-03-08
HK1047099A1 (hu) 2003-02-07
PL327581A1 (en) 1998-12-21
DE69621463D1 (de) 2002-07-04
DK0889885T3 (da) 2002-09-16
CN1356326A (zh) 2002-07-03
US6180802B1 (en) 2001-01-30
IL138769A (en) 2006-04-10
SK88498A3 (en) 1998-11-04
CN1356325A (zh) 2002-07-03
KR100510017B1 (ko) 2005-12-16

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Legal Events

Date Code Title Description
FC4A Lapse of provisional application due to refusal