IL124652A - Screening assay for compounds stimulating somatostatin and insulin production - Google Patents

Screening assay for compounds stimulating somatostatin and insulin production

Info

Publication number
IL124652A
IL124652A IL12465296A IL12465296A IL124652A IL 124652 A IL124652 A IL 124652A IL 12465296 A IL12465296 A IL 12465296A IL 12465296 A IL12465296 A IL 12465296A IL 124652 A IL124652 A IL 124652A
Authority
IL
Israel
Prior art keywords
insulin production
screening assay
compounds
binding
somatostatin
Prior art date
Application number
IL12465296A
Other languages
English (en)
Other versions
IL124652A0 (en
Inventor
Marc R Montminy
Bernard Peers
Original Assignee
Res Dev Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Res Dev Foundation filed Critical Res Dev Foundation
Publication of IL124652A0 publication Critical patent/IL124652A0/xx
Publication of IL124652A publication Critical patent/IL124652A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Analytical Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Cell Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
IL12465296A 1995-11-30 1996-11-27 Screening assay for compounds stimulating somatostatin and insulin production IL124652A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US772295P 1995-11-30 1995-11-30
PCT/US1996/019009 WO1997020075A1 (en) 1995-11-30 1996-11-27 Screening assay for compounds stimulating somatostatin and insulin production

Publications (2)

Publication Number Publication Date
IL124652A0 IL124652A0 (en) 1998-12-06
IL124652A true IL124652A (en) 2000-11-21

Family

ID=21727790

Family Applications (1)

Application Number Title Priority Date Filing Date
IL12465296A IL124652A (en) 1995-11-30 1996-11-27 Screening assay for compounds stimulating somatostatin and insulin production

Country Status (14)

Country Link
US (1) US5849493A (xx)
EP (1) EP0954598B1 (xx)
JP (1) JP2000501290A (xx)
KR (1) KR100456183B1 (xx)
CN (1) CN1117876C (xx)
AT (1) ATE321880T1 (xx)
AU (1) AU719614B2 (xx)
CA (1) CA2237717C (xx)
DE (1) DE69635998D1 (xx)
IL (1) IL124652A (xx)
NZ (1) NZ324951A (xx)
RU (1) RU2178714C2 (xx)
WO (1) WO1997020075A1 (xx)
ZA (1) ZA9610080B (xx)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5427905A (en) 1994-07-13 1995-06-27 Polaroid Corporation Thermally processable image-recording material including reductone developing agent
US5849989A (en) * 1994-10-07 1998-12-15 Ontogeny, Inc. Insulin promoter factor, and uses related thereto
US8778899B2 (en) 1999-06-01 2014-07-15 Sarah Ferber Methods of inducing regulated pancreatic hormone production in non-pancreatic islet tissues
US6774120B1 (en) * 1999-06-01 2004-08-10 Sarah Ferber Methods of inducing regulated pancreatic hormone production in non-pancreatic islet tissues
US6924113B2 (en) 2001-06-08 2005-08-02 Panomics, Inc. Method and kit for isolating DNA probes that bind to activated transcription factors
US20040214166A1 (en) * 2001-06-08 2004-10-28 Xianqiang Li Method for identifying a disease state based on a detected mixture of activated transcription factors
US7981842B2 (en) 2001-06-08 2011-07-19 Panomics, Inc. Method for detecting transcription factor-protein interactions
US6821737B2 (en) 2001-06-08 2004-11-23 Panomics, Inc. Method for screening for drug candidates for modulating transcription factor activity
US6696256B1 (en) 2001-06-08 2004-02-24 Pandmics, Inc. Method, array and kit for detecting activated transcription factors by hybridization array
US6642003B2 (en) 2001-08-02 2003-11-04 Cedars-Sinai Medical Center Human glucose-dependent insulin-secreting cell line
US20030143547A1 (en) * 2002-01-24 2003-07-31 Xianqiang Li Method for identifying multiple activated transcription factors
US7141240B2 (en) * 2002-03-12 2006-11-28 Cedars-Sinai Medical Center Glucose-dependent insulin-secreting cells transfected with a nucleotide sequence encoding GLP-1
EP1706134A2 (en) * 2004-01-20 2006-10-04 DeveloGen Aktiengesellschaft Use of protein products for preventing and treating pancreatic diseases and/or obestiy and/or metabolic syndrome
EP2558622A4 (en) 2010-04-06 2013-07-24 Univ George Washington COMPOSITIONS AND METHODS FOR IDENTIFYING INTERFERENCE FROM THE AUTISM SPECTRUM
US9132194B2 (en) 2011-07-12 2015-09-15 Warsaw Orthopedic, Inc. Medical devices and methods comprising an adhesive sheet containing a drug depot
US9205241B2 (en) 2011-07-12 2015-12-08 Warsaw Orthopedic, Inc. Medical devices and methods comprising an adhesive material
CN105555950B (zh) 2013-06-13 2021-03-05 奥尔吉尼西丝有限公司 细胞群体、转分化的方法及其使用方法
MA41296A (fr) 2014-12-30 2017-11-07 Orgenesis Ltd Procédés de transdifférenciation et procédés d'utilisation de ceux-ci
WO2018017657A1 (en) * 2016-07-20 2018-01-25 The Johns Hopkins University Oxygen gradient hydrogel drug screening
WO2018207179A1 (en) 2017-05-08 2018-11-15 Orgenesis Ltd. Transdifferentiated cell populations and methods of use thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3802051B2 (ja) * 1993-08-16 2006-07-26 リサーチ ディベロップメント ファンデーション 膵臓島細胞におけるインシュリン表現を刺激する新しいホメオボックス因子
US5612455A (en) * 1994-07-05 1997-03-18 Tularik, Inc. Nuclear factors and binding assay

Also Published As

Publication number Publication date
JP2000501290A (ja) 2000-02-08
EP0954598A1 (en) 1999-11-10
EP0954598B1 (en) 2006-03-29
CN1117876C (zh) 2003-08-13
CA2237717A1 (en) 1997-06-05
WO1997020075A1 (en) 1997-06-05
EP0954598A4 (en) 2002-10-30
NZ324951A (en) 1999-04-29
AU719614B2 (en) 2000-05-11
RU2178714C2 (ru) 2002-01-27
ZA9610080B (en) 1998-05-29
AU1274997A (en) 1997-06-19
CN1202936A (zh) 1998-12-23
DE69635998D1 (de) 2006-05-18
ATE321880T1 (de) 2006-04-15
US5849493A (en) 1998-12-15
KR100456183B1 (ko) 2005-06-13
CA2237717C (en) 2010-07-27
KR19990071797A (ko) 1999-09-27
IL124652A0 (en) 1998-12-06

Similar Documents

Publication Publication Date Title
IL124652A (en) Screening assay for compounds stimulating somatostatin and insulin production
HK1101639A1 (en) Nucleic acids encoding a g-protein coupled receptor involved in sensory transduction
DE3869969D1 (de) Versuchsmethode unter verwendung von partikeln mit assoziiertem, fluoreszierendem stoff.
ATE408422T1 (de) Methode zur hemmung immunstimulatorischer mit dna assoziierter antworten
ID22852A (id) Bahan-bahan biokontrol antifungi, proses untuk membuatnya dan memperlakukannya
DE69818445D1 (de) Verwendung von verbindungen die an ein zytoplasmatischen dipeptidase binden zur potenzierung des immunantworts
DE69941701D1 (de) Mutanten von flt3-l und ihre verwendungen
PL313256A1 (en) Protocadherine proteins and their applications
CA2111573A1 (en) Cadherin materials and methods
EP1181555A4 (en) CANCER TREATMENT WITH ENDOTHELINE RECEPTOR ANTAGONISTS
DE69804690D1 (de) Hilfe zum Räumen von Minen
DE68903255D1 (de) Sieb zur reinigung und klassifizierung von papierstoffbrei.
DE69007997D1 (de) Sieb-Konstruktion zum Reinigung von elastomeren Materialien.
DE3874135D1 (de) Einrichtung zum festmachen/tragen von schiffskonstruktionen.
ATE204172T1 (de) Endothelin-rezeptorantagonisten zur bekämpfung von hyperlipidämie
DE3765125D1 (de) Seismischer schwingungserzeuger zur kombinierten erregung von kompressions- und schubwellen.
EP1137413A4 (en) NON-PEPTIDE GLP-1 RECEPTOR ANTAGONISTS AND TECHNIQUES FOR USE
DE69615285D1 (de) System zum Raffinieren von Gasen
ATE305037T1 (de) Peptide, die fähig sind die sh3-domäne des gap- proteins zu binden, ihre kodierende dns, ihre zubereitung und verwendung
DE69618095D1 (de) Vorrichtung zum Zuführen von flachen Materialien
DE69817380D1 (de) Verfahren zur verstärkung der farben von mineralen, die als edelsteine benutzt werden
WO2002018941A3 (en) Screen for glutamate reuptake inhibitors, stimulators, and modulators
WO2002000719A3 (en) Human and mouse g-protein couipled receptors
DE59800472D1 (de) Reaktionsmischung zur Abdichtung von Rohrverbindungen, Sanierverfahren und Verwendung
DE69807136D1 (de) Verfahren zur Identifizierung von Substanzen, die die Bindung von TL2 (TRAIL) an TR5 hemmen oder stimulieren.

Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
KB Patent renewed
KB Patent renewed
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees