DE69635998D1 - Nachweisverfahren für verbindungen, welche die somatostatin- und insulinproduktion stimulieren - Google Patents

Nachweisverfahren für verbindungen, welche die somatostatin- und insulinproduktion stimulieren

Info

Publication number
DE69635998D1
DE69635998D1 DE69635998T DE69635998T DE69635998D1 DE 69635998 D1 DE69635998 D1 DE 69635998D1 DE 69635998 T DE69635998 T DE 69635998T DE 69635998 T DE69635998 T DE 69635998T DE 69635998 D1 DE69635998 D1 DE 69635998D1
Authority
DE
Germany
Prior art keywords
insulin production
somatostat
detection method
compounds
binding
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69635998T
Other languages
English (en)
Inventor
R Montminy
Bernard Peers
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Research Development Foundation
Original Assignee
Research Development Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Research Development Foundation filed Critical Research Development Foundation
Application granted granted Critical
Publication of DE69635998D1 publication Critical patent/DE69635998D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Analytical Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Cell Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
DE69635998T 1995-11-30 1996-11-27 Nachweisverfahren für verbindungen, welche die somatostatin- und insulinproduktion stimulieren Expired - Lifetime DE69635998D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US772295P 1995-11-30 1995-11-30
PCT/US1996/019009 WO1997020075A1 (en) 1995-11-30 1996-11-27 Screening assay for compounds stimulating somatostatin and insulin production

Publications (1)

Publication Number Publication Date
DE69635998D1 true DE69635998D1 (de) 2006-05-18

Family

ID=21727790

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69635998T Expired - Lifetime DE69635998D1 (de) 1995-11-30 1996-11-27 Nachweisverfahren für verbindungen, welche die somatostatin- und insulinproduktion stimulieren

Country Status (14)

Country Link
US (1) US5849493A (de)
EP (1) EP0954598B1 (de)
JP (1) JP2000501290A (de)
KR (1) KR100456183B1 (de)
CN (1) CN1117876C (de)
AT (1) ATE321880T1 (de)
AU (1) AU719614B2 (de)
CA (1) CA2237717C (de)
DE (1) DE69635998D1 (de)
IL (1) IL124652A (de)
NZ (1) NZ324951A (de)
RU (1) RU2178714C2 (de)
WO (1) WO1997020075A1 (de)
ZA (1) ZA9610080B (de)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5427905A (en) 1994-07-13 1995-06-27 Polaroid Corporation Thermally processable image-recording material including reductone developing agent
US5849989A (en) * 1994-10-07 1998-12-15 Ontogeny, Inc. Insulin promoter factor, and uses related thereto
US8778899B2 (en) 1999-06-01 2014-07-15 Sarah Ferber Methods of inducing regulated pancreatic hormone production in non-pancreatic islet tissues
US6774120B1 (en) * 1999-06-01 2004-08-10 Sarah Ferber Methods of inducing regulated pancreatic hormone production in non-pancreatic islet tissues
US7981842B2 (en) 2001-06-08 2011-07-19 Panomics, Inc. Method for detecting transcription factor-protein interactions
US20040214166A1 (en) * 2001-06-08 2004-10-28 Xianqiang Li Method for identifying a disease state based on a detected mixture of activated transcription factors
US6696256B1 (en) 2001-06-08 2004-02-24 Pandmics, Inc. Method, array and kit for detecting activated transcription factors by hybridization array
US6924113B2 (en) 2001-06-08 2005-08-02 Panomics, Inc. Method and kit for isolating DNA probes that bind to activated transcription factors
US6821737B2 (en) 2001-06-08 2004-11-23 Panomics, Inc. Method for screening for drug candidates for modulating transcription factor activity
US6642003B2 (en) 2001-08-02 2003-11-04 Cedars-Sinai Medical Center Human glucose-dependent insulin-secreting cell line
US20030143547A1 (en) * 2002-01-24 2003-07-31 Xianqiang Li Method for identifying multiple activated transcription factors
US7141240B2 (en) * 2002-03-12 2006-11-28 Cedars-Sinai Medical Center Glucose-dependent insulin-secreting cells transfected with a nucleotide sequence encoding GLP-1
EP1706134A2 (de) * 2004-01-20 2006-10-04 DeveloGen Aktiengesellschaft Verwendung von proteinprodukten zur prophylaxe und therapie von pankreas-erkrankungen und/oder fettleibigkeit und/oder stoffwechselsyndrom
WO2011127194A1 (en) 2010-04-06 2011-10-13 The George Washington University Compositions and methods for identifying autism spectrum disorders
US9132194B2 (en) 2011-07-12 2015-09-15 Warsaw Orthopedic, Inc. Medical devices and methods comprising an adhesive sheet containing a drug depot
US9205241B2 (en) 2011-07-12 2015-12-08 Warsaw Orthopedic, Inc. Medical devices and methods comprising an adhesive material
CA2915143C (en) 2013-06-13 2021-08-03 Orgenesis Ltd. Cell populations, methods of transdifferentiation and methods of use thereof
MA41296A (fr) 2014-12-30 2017-11-07 Orgenesis Ltd Procédés de transdifférenciation et procédés d'utilisation de ceux-ci
US11530381B2 (en) * 2016-07-20 2022-12-20 The Johns Hopkins University Oxygen gradient hydrogel drug screening
EP3635106A4 (de) 2017-05-08 2021-01-06 Orgenesis Ltd. Transdifferenzierte zellpopulationen und verfahren zur verwendung davon

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0714438B1 (de) * 1993-08-16 2007-09-19 RESEARCH DEVELOPMENT FOUNDATION (a Nevada corporation) Ein homeobox-faktor der insulin-expression in pankreatischen inselnzellen stimuliert
US5612455A (en) * 1994-07-05 1997-03-18 Tularik, Inc. Nuclear factors and binding assay

Also Published As

Publication number Publication date
US5849493A (en) 1998-12-15
WO1997020075A1 (en) 1997-06-05
IL124652A (en) 2000-11-21
CA2237717C (en) 2010-07-27
KR19990071797A (ko) 1999-09-27
RU2178714C2 (ru) 2002-01-27
ZA9610080B (en) 1998-05-29
CA2237717A1 (en) 1997-06-05
IL124652A0 (en) 1998-12-06
AU719614B2 (en) 2000-05-11
CN1202936A (zh) 1998-12-23
EP0954598A4 (de) 2002-10-30
JP2000501290A (ja) 2000-02-08
ATE321880T1 (de) 2006-04-15
EP0954598A1 (de) 1999-11-10
KR100456183B1 (ko) 2005-06-13
CN1117876C (zh) 2003-08-13
AU1274997A (en) 1997-06-19
NZ324951A (en) 1999-04-29
EP0954598B1 (de) 2006-03-29

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