IL121474A0 - Thrombin inhibitors - Google Patents

Thrombin inhibitors

Info

Publication number
IL121474A0
IL121474A0 IL12147497A IL12147497A IL121474A0 IL 121474 A0 IL121474 A0 IL 121474A0 IL 12147497 A IL12147497 A IL 12147497A IL 12147497 A IL12147497 A IL 12147497A IL 121474 A0 IL121474 A0 IL 121474A0
Authority
IL
Israel
Prior art keywords
thrombin inhibitors
thrombin
inhibitors
Prior art date
Application number
IL12147497A
Other languages
English (en)
Original Assignee
Akzo Nobel Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akzo Nobel Nv filed Critical Akzo Nobel Nv
Publication of IL121474A0 publication Critical patent/IL121474A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/022—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2
    • C07K5/0222—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2 with the first amino acid being heterocyclic, e.g. Pro, Trp
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
IL12147497A 1996-08-23 1997-08-05 Thrombin inhibitors IL121474A0 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP96202336 1996-08-23

Publications (1)

Publication Number Publication Date
IL121474A0 true IL121474A0 (en) 1998-02-08

Family

ID=8224306

Family Applications (1)

Application Number Title Priority Date Filing Date
IL12147497A IL121474A0 (en) 1996-08-23 1997-08-05 Thrombin inhibitors

Country Status (10)

Country Link
EP (1) EP0956293B1 (xx)
AR (1) AR009302A1 (xx)
AT (1) ATE282629T1 (xx)
AU (1) AU4618197A (xx)
DE (1) DE69731664D1 (xx)
ID (1) ID18075A (xx)
IL (1) IL121474A0 (xx)
TW (1) TW515803B (xx)
WO (1) WO1998007308A2 (xx)
ZA (1) ZA977209B (xx)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5877156A (en) * 1997-04-24 1999-03-02 Akzo Nobel, N.V. Thrombin inhibitors
EP0884325A1 (en) * 1997-04-24 1998-12-16 Akzo Nobel N.V. Thrombin inhibitors containing a peptidyl heterocycle
GB0507577D0 (en) 2005-04-14 2005-05-18 Novartis Ag Organic compounds
JP2009538327A (ja) 2006-05-23 2009-11-05 アイアールエム・リミテッド・ライアビリティ・カンパニー チャネル活性化プロテアーゼ阻害剤である化合物および組成物
DE602007013387D1 (de) * 2006-05-23 2011-05-05 Irm Llc Verbindungen und zusammensetzungen als kanalaktivierende protease-hemmer
MX2009008518A (es) 2007-02-09 2009-08-20 Irm Llc Compuestos y composiciones como inhibidores de la proteasa activadora de canal.

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5672582A (en) * 1993-04-30 1997-09-30 Merck & Co., Inc. Thrombin inhibitors
SE9301916D0 (sv) * 1993-06-03 1993-06-03 Ab Astra New peptides derivatives
ZA951617B (en) * 1994-03-04 1997-02-27 Lilly Co Eli Antithrombotic agents.
EP0799240A1 (en) * 1994-12-22 1997-10-08 Biochem Pharma Inc Heterocyclic keto arginine peptides as thrombin inhibitors
US5827860A (en) * 1995-06-07 1998-10-27 Ortho Pharmaceutical Corporation Peptidyl heterocycles useful in the treatment of thrombin related disorders
IL119466A (en) * 1995-11-03 2001-08-26 Akzo Nobel Nv Thrombin inhibitors, their preparation and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
WO1998007308A3 (en) 2000-08-24
EP0956293B1 (en) 2004-11-17
ZA977209B (en) 1998-02-20
ATE282629T1 (de) 2004-12-15
ID18075A (id) 1998-02-26
TW515803B (en) 2003-01-01
EP0956293A1 (en) 1999-11-17
WO1998007308A2 (en) 1998-02-26
AU4618197A (en) 1998-03-06
DE69731664D1 (de) 2004-12-23
AR009302A1 (es) 2000-04-12

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