IL116142A0 - Method of using triaryl-ethylene derivatives in the treatment and prevention of osteoporosis - Google Patents
Method of using triaryl-ethylene derivatives in the treatment and prevention of osteoporosisInfo
- Publication number
- IL116142A0 IL116142A0 IL11614295A IL11614295A IL116142A0 IL 116142 A0 IL116142 A0 IL 116142A0 IL 11614295 A IL11614295 A IL 11614295A IL 11614295 A IL11614295 A IL 11614295A IL 116142 A0 IL116142 A0 IL 116142A0
- Authority
- IL
- Israel
- Prior art keywords
- triaryl
- osteoporosis
- prevention
- treatment
- ethylene derivatives
- Prior art date
Links
- 208000001132 Osteoporosis Diseases 0.000 title 1
- 230000002265 prevention Effects 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/136—Amines having aromatic rings, e.g. ketamine, nortriptyline having the amino group directly attached to the aromatic ring, e.g. benzeneamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4453—Non condensed piperidines, e.g. piperocaine only substituted in position 1, e.g. propipocaine, diperodon
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Physical Education & Sports Medicine (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IL12943199A IL129431A0 (en) | 1994-11-29 | 1999-04-13 | Method of using triaryl-ethylene derivatives in the treatment and prevention of osteoporosis |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US34611194A | 1994-11-29 | 1994-11-29 | |
US08/531,885 US5691384A (en) | 1994-11-29 | 1995-10-11 | Method of using triaryl-ethylene derivatives in the treatment and prevention of osteoporosis |
Publications (1)
Publication Number | Publication Date |
---|---|
IL116142A0 true IL116142A0 (en) | 1996-01-31 |
Family
ID=26994698
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL11614295A IL116142A0 (en) | 1994-11-29 | 1995-11-27 | Method of using triaryl-ethylene derivatives in the treatment and prevention of osteoporosis |
Country Status (12)
Country | Link |
---|---|
US (1) | US5693674A (xx) |
EP (1) | EP0794771A1 (xx) |
JP (1) | JPH10509962A (xx) |
CN (1) | CN1167437A (xx) |
AU (1) | AU707290B2 (xx) |
CA (1) | CA2206422A1 (xx) |
FI (1) | FI972235A (xx) |
HU (1) | HUT77603A (xx) |
IL (1) | IL116142A0 (xx) |
MX (1) | MX9703944A (xx) |
NO (1) | NO972426L (xx) |
WO (1) | WO1996016646A1 (xx) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7005428B1 (en) | 1998-06-11 | 2006-02-28 | Endorecherche, Inc. | Medical uses of a selective estrogen receptor modulator in combination with sex steroid precursors |
US6465445B1 (en) | 1998-06-11 | 2002-10-15 | Endorecherche, Inc. | Medical uses of a selective estrogen receptor modulator in combination with sex steroid precursors |
TW593256B (en) | 1999-11-16 | 2004-06-21 | Hormos Medical Oy Ltd | Triphenylalkene derivatives and their use as selective estrogen receptor modulators |
US20040248989A1 (en) | 2003-06-05 | 2004-12-09 | Risto Santti | Method for the treatment or prevention of lower urinary tract symptoms |
KR101505884B1 (ko) * | 2006-05-22 | 2015-03-25 | 호르모스 메디칼 리미티드 | 만성 비세균성 전립선염 치료용 선택적 에스트로겐 수용체 조절제 또는 아로마타아제 저해제 |
WO2008099060A2 (en) * | 2007-02-14 | 2008-08-21 | Hormos Medical Ltd | Methods for the preparation of fispemifene from ospemifene |
EP2518039B8 (en) * | 2007-02-14 | 2014-12-17 | Forendo Pharma Ltd. | Method for the preparation of therapeutically valuable triphenylbutene derivatives |
EP3252032A1 (en) | 2008-07-02 | 2017-12-06 | British Columbia Cancer Agency Branch | Diglycidic ether derivative therapeutics and methods for their use |
US9321712B2 (en) | 2012-10-19 | 2016-04-26 | Fermion Oy | Process for the preparation of ospemifene |
JP6884100B2 (ja) * | 2015-01-13 | 2021-06-09 | ブリティッシュ コロンビア キャンサー エージェンシー ブランチ | がんの画像化及び治療用のヘテロ環式化合物ならびにそれらの使用方法 |
WO2016141458A1 (en) | 2015-03-12 | 2016-09-15 | British Columbia Cancer Agency Branch | Bisphenol ether derivatives and methods for using the same |
US20170298033A1 (en) | 2016-04-15 | 2017-10-19 | The University Of British Columbia | Bisphenol derivatives and their use as androgen receptor activity modulators |
WO2019226991A1 (en) | 2018-05-25 | 2019-11-28 | Essa Pharma, Inc. | Androgen receptor modulators and methods for their use |
KR20210093886A (ko) | 2018-10-18 | 2021-07-28 | 에싸 파마 아이엔씨. | 안드로겐 수용체 조절제 및 그 사용 방법 |
EP4135675A4 (en) | 2020-04-17 | 2024-04-10 | Essa Pharma, Inc. | SOLID FORMS OF AN N-TERMINAL DOMAIN ANDROGEN RECEPTOR INHIBITOR AND USES THEREOF |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2914563A (en) * | 1957-08-06 | 1959-11-24 | Wm S Merrell Co | Therapeutic composition |
GB1013907A (en) * | 1962-09-13 | 1965-12-22 | Ici Ltd | Alkene derivatives |
US3247252A (en) * | 1962-11-14 | 1966-04-19 | Richardson Merrell Inc | Beta-dialkylaminoethylamino-triphenylethanols, -ethanes, and -ethenes |
GB1099093A (en) * | 1965-09-03 | 1968-01-17 | Ici Ltd | Alkene derivatives |
GB1128379A (en) * | 1966-06-20 | 1968-09-25 | Ici Ltd | Novel alkene derivatives, process for the preparation thereof and compositions containing the same |
US4001229A (en) * | 1974-04-04 | 1977-01-04 | Mead Johnson & Company | Alkanesulfonamido triphenylethylenes |
EP0002097B1 (en) * | 1977-08-22 | 1981-08-05 | Imperial Chemical Industries Plc | Triphenylalkene derivatives, process for their preparation and pharmaceutical compositions containing them |
US4729999A (en) * | 1984-10-12 | 1988-03-08 | Bcm Technologies | Antiestrogen therapy for symptoms of estrogen deficiency |
US4970237A (en) * | 1987-03-20 | 1990-11-13 | Yale University | Use of clomiphene to increase bone mass in premenopausal women |
JPH06312930A (ja) * | 1993-04-30 | 1994-11-08 | Kuraray Co Ltd | 骨粗鬆症治療剤 |
US5525633A (en) * | 1993-09-24 | 1996-06-11 | Merrell Dow Pharmaceuticals Inc. | Triaryl-ethylene derivatives |
NZ272608A (en) * | 1994-07-22 | 2000-05-26 | Lilly Co Eli | Inhibiting bone loss by administering a bisphosphonate and a second compound selected from various compounds, including 2-phenyl-3-aroylbenzothienes; bisphosphonate combination salts |
-
1995
- 1995-10-27 CN CN95196510A patent/CN1167437A/zh active Pending
- 1995-10-27 JP JP8517877A patent/JPH10509962A/ja active Pending
- 1995-10-27 EP EP95940561A patent/EP0794771A1/en not_active Withdrawn
- 1995-10-27 MX MX9703944A patent/MX9703944A/es unknown
- 1995-10-27 WO PCT/US1995/013873 patent/WO1996016646A1/en not_active Application Discontinuation
- 1995-10-27 CA CA002206422A patent/CA2206422A1/en not_active Abandoned
- 1995-10-27 AU AU41967/96A patent/AU707290B2/en not_active Ceased
- 1995-10-27 HU HU9702022A patent/HUT77603A/hu unknown
- 1995-11-27 IL IL11614295A patent/IL116142A0/xx unknown
-
1996
- 1996-06-12 US US08/662,092 patent/US5693674A/en not_active Expired - Fee Related
-
1997
- 1997-05-27 FI FI972235A patent/FI972235A/fi unknown
- 1997-05-28 NO NO972426A patent/NO972426L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
JPH10509962A (ja) | 1998-09-29 |
FI972235A0 (fi) | 1997-05-27 |
HUT77603A (hu) | 1998-06-29 |
CN1167437A (zh) | 1997-12-10 |
NO972426D0 (no) | 1997-05-28 |
AU707290B2 (en) | 1999-07-08 |
NO972426L (no) | 1997-07-29 |
FI972235A (fi) | 1997-05-27 |
WO1996016646A1 (en) | 1996-06-06 |
CA2206422A1 (en) | 1996-06-06 |
EP0794771A1 (en) | 1997-09-17 |
MX9703944A (es) | 1998-05-31 |
US5693674A (en) | 1997-12-02 |
AU4196796A (en) | 1996-06-19 |
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