IL114951A - Quinazolinone-containing pharmaceutical compositions for prevention of neovascularization - Google Patents

Quinazolinone-containing pharmaceutical compositions for prevention of neovascularization

Info

Publication number
IL114951A
IL114951A IL11495195A IL11495195A IL114951A IL 114951 A IL114951 A IL 114951A IL 11495195 A IL11495195 A IL 11495195A IL 11495195 A IL11495195 A IL 11495195A IL 114951 A IL114951 A IL 114951A
Authority
IL
Israel
Prior art keywords
group
quinazolinone
neovascularization
prevention
pharmaceutical compositions
Prior art date
Application number
IL11495195A
Other languages
English (en)
Other versions
IL114951A0 (en
Inventor
Nagler Arnon
Slavin Shimon
Vlodavsky Israel
Pines Mark
Original Assignee
Hadasit Med Res Service
Agricultural Res Org
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hadasit Med Res Service, Agricultural Res Org filed Critical Hadasit Med Res Service
Priority to IL11495195A priority Critical patent/IL114951A/xx
Publication of IL114951A0 publication Critical patent/IL114951A0/xx
Priority to ES96928874T priority patent/ES2231824T3/es
Priority to AT96928874T priority patent/ATE279925T1/de
Priority to JP50946697A priority patent/JP4101875B2/ja
Priority to DK96928874T priority patent/DK0850062T3/da
Priority to US09/011,696 priority patent/US6090814A/en
Priority to CN96196609A priority patent/CN1113652C/zh
Priority to CA002228524A priority patent/CA2228524C/fr
Priority to PCT/US1996/013210 priority patent/WO1997006805A1/fr
Priority to DE69633673T priority patent/DE69633673T2/de
Priority to AU68469/96A priority patent/AU705955B2/en
Priority to EP96928874A priority patent/EP0850062B1/fr
Publication of IL114951A publication Critical patent/IL114951A/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Steroid Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
IL11495195A 1995-08-15 1995-08-15 Quinazolinone-containing pharmaceutical compositions for prevention of neovascularization IL114951A (en)

Priority Applications (12)

Application Number Priority Date Filing Date Title
IL11495195A IL114951A (en) 1995-08-15 1995-08-15 Quinazolinone-containing pharmaceutical compositions for prevention of neovascularization
EP96928874A EP0850062B1 (fr) 1995-08-15 1996-08-12 Utilisation de halofuginone pour l'obtention d'un médicament pour la prévention de la neovascularisation et le traitement de tumeurs malignes
DK96928874T DK0850062T3 (da) 1995-08-15 1996-08-12 Anvendelse af halofuginon til fremstilling af et medikament til svækkelse af neovaskularisering og til behandling af maligne tumorer hos mennesker
AT96928874T ATE279925T1 (de) 1995-08-15 1996-08-12 Verwendung von halofuginon zur herstellung eines medikaments zur vorbeugung von neovaskularisation und zur behandlung bösartiger tumore
JP50946697A JP4101875B2 (ja) 1995-08-15 1996-08-12 新生血管形成の予防及びヒト悪性疾患の処置のためのキナゾリノン含有薬理組成物
ES96928874T ES2231824T3 (es) 1995-08-15 1996-08-12 Uso de halofuginona para la preparacion de un medicamento para atenuar la neovascularizacion y para tratar tumores malignos en seres humanos.
US09/011,696 US6090814A (en) 1995-08-15 1996-08-12 Quinazolinone-containing pharmaceutical compositions for prevention of neovascularization
CN96196609A CN1113652C (zh) 1995-08-15 1996-08-12 用于预防新血管生成及治疗人类恶性肿瘤的含喹唑啉酮的药物组合物
CA002228524A CA2228524C (fr) 1995-08-15 1996-08-12 Compositions pharmaceutiques contenant de la quinazolinone, et prevenant la neo-vascularisation et permettant le traitement de tumeurs malignes humaines
PCT/US1996/013210 WO1997006805A1 (fr) 1995-08-15 1996-08-12 Compositions pharmaceutiques contenant de la quinazolinone, et prevenant la neo-vascularisation et permettant le traitement de tumeurs malignes humaines
DE69633673T DE69633673T2 (de) 1995-08-15 1996-08-12 Verwendung von Halofuginon zur Herstellung eines Medikaments zur Vorbeugung von Neovaskularisation und zur Behandlung bösartiger Tumoren
AU68469/96A AU705955B2 (en) 1995-08-15 1996-08-12 Quinazolinone-containing pharmaceutical compositions for prevention of neovascularization and for treating human malignancies

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IL11495195A IL114951A (en) 1995-08-15 1995-08-15 Quinazolinone-containing pharmaceutical compositions for prevention of neovascularization

Publications (2)

Publication Number Publication Date
IL114951A0 IL114951A0 (en) 1995-12-08
IL114951A true IL114951A (en) 1999-08-17

Family

ID=11067877

Family Applications (1)

Application Number Title Priority Date Filing Date
IL11495195A IL114951A (en) 1995-08-15 1995-08-15 Quinazolinone-containing pharmaceutical compositions for prevention of neovascularization

Country Status (11)

Country Link
EP (1) EP0850062B1 (fr)
JP (1) JP4101875B2 (fr)
CN (1) CN1113652C (fr)
AT (1) ATE279925T1 (fr)
AU (1) AU705955B2 (fr)
CA (1) CA2228524C (fr)
DE (1) DE69633673T2 (fr)
DK (1) DK0850062T3 (fr)
ES (1) ES2231824T3 (fr)
IL (1) IL114951A (fr)
WO (1) WO1997006805A1 (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6440445B1 (en) 1996-09-30 2002-08-27 Brigham & Women's Hospital Methods and compounds for treatment of abnormal uterine bleeding
US6028075A (en) * 1997-02-11 2000-02-22 Pines; Mark Quinazolinone containing pharmaceutical compositions for prevention of neovascularization and for treating malignancies
IT1316986B1 (it) 2000-01-25 2003-05-26 Sigma Tau Ind Farmaceuti Derivati glicosamminoglicani parzialmente desolfatati nonanticoagulanti ad attivita' antiangiogenica.
IL147416A (en) * 2001-12-31 2008-11-26 Israel State Combined modalities for improved cancer treatment
CN100434425C (zh) * 2005-03-09 2008-11-19 首都师范大学 4-喹唑啉酮衍生物及其在抗肿瘤药物中的应用
CN102653521B (zh) * 2012-04-27 2014-08-06 首都师范大学 吲哚-2-酮的哌嗪硫代甲酰肼衍生物及其制备方法和用途
AR110963A1 (es) 2017-02-07 2019-05-22 Dae Woong Pharma Compuestos heterocíclicos, su método de preparación y composición farmacéutica que los comprende

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3320124A (en) * 1964-07-20 1967-05-16 American Cyanamid Co Method for treating coccidiosis with quinazolinones
DE2934069A1 (de) * 1979-08-23 1981-03-12 Hoechst Ag, 6000 Frankfurt Mittel gegen theileriosen und seine verwendung.
DE3638446A1 (de) * 1986-11-11 1988-05-26 Hoechst Ag Coccidiozide mittel
CA2113229C (fr) * 1994-01-11 1999-04-20 Mark Pines Compositions anti-fibreuses contenant de la quinazolinone et methodes d'utilisation correspondantes
IL110831A (en) * 1994-08-31 1998-12-27 Hadasit Med Res Service Pharmaceutical compositions containing quinazolinone derivatives for preventing restenosis
IL112125A (en) * 1994-12-22 1998-02-08 Hadasit Med Res Service Quinazolinone-containing pharmaceutical compositions

Also Published As

Publication number Publication date
ES2231824T3 (es) 2005-05-16
EP0850062A4 (fr) 2000-03-15
JP4101875B2 (ja) 2008-06-18
JPH11511172A (ja) 1999-09-28
CA2228524C (fr) 2003-01-07
CN1194583A (zh) 1998-09-30
AU6846996A (en) 1997-03-12
AU705955B2 (en) 1999-06-03
CN1113652C (zh) 2003-07-09
EP0850062B1 (fr) 2004-10-20
IL114951A0 (en) 1995-12-08
DE69633673D1 (de) 2004-11-25
EP0850062A1 (fr) 1998-07-01
ATE279925T1 (de) 2004-11-15
WO1997006805A1 (fr) 1997-02-27
DE69633673T2 (de) 2006-02-09
CA2228524A1 (fr) 1997-02-27
DK0850062T3 (da) 2005-02-07

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Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees