IL114236A - 5, 5-diphenylhydantoin derivatives, pharmaceutical compositions containing the same and a process for the preparation thereof - Google Patents

5, 5-diphenylhydantoin derivatives, pharmaceutical compositions containing the same and a process for the preparation thereof

Info

Publication number
IL114236A
IL114236A IL114236A IL11423695A IL114236A IL 114236 A IL114236 A IL 114236A IL 114236 A IL114236 A IL 114236A IL 11423695 A IL11423695 A IL 11423695A IL 114236 A IL114236 A IL 114236A
Authority
IL
Israel
Prior art keywords
product
preparation
formula
phenytoin
addition salt
Prior art date
Application number
IL114236A
Other languages
English (en)
Other versions
IL114236A0 (en
Original Assignee
Rubio Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rubio Lab filed Critical Rubio Lab
Publication of IL114236A0 publication Critical patent/IL114236A0/xx
Publication of IL114236A publication Critical patent/IL114236A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/72Two oxygen atoms, e.g. hydantoin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicinal Preparation (AREA)
IL114236A 1994-07-22 1995-06-20 5, 5-diphenylhydantoin derivatives, pharmaceutical compositions containing the same and a process for the preparation thereof IL114236A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES09401625A ES2085832B1 (es) 1994-07-22 1994-07-22 Profarmacos de la 5,5-difenilhidantoina.

Publications (2)

Publication Number Publication Date
IL114236A0 IL114236A0 (en) 1995-10-31
IL114236A true IL114236A (en) 1998-06-15

Family

ID=8287022

Family Applications (1)

Application Number Title Priority Date Filing Date
IL114236A IL114236A (en) 1994-07-22 1995-06-20 5, 5-diphenylhydantoin derivatives, pharmaceutical compositions containing the same and a process for the preparation thereof

Country Status (4)

Country Link
EP (1) EP0693481A1 (es)
JP (1) JPH08183777A (es)
ES (1) ES2085832B1 (es)
IL (1) IL114236A (es)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4163058A (en) * 1977-04-22 1979-07-31 Interx Research Corporation Derivatives of 5,5-diphenylhydantoin exhibiting enhanced solubility and the therapeutic use thereof
US4260769A (en) 1977-04-22 1981-04-07 Interx Research Corporation 5,5-Diphenylhydantoins
US5002935A (en) * 1987-12-30 1991-03-26 University Of Florida Improvements in redox systems for brain-targeted drug delivery
DK24089D0 (da) 1989-01-20 1989-01-20 Hans Bundgaard Novel prodrug derivatives of biologically active agents containing hydroxyl groups or nh-acidic groups

Also Published As

Publication number Publication date
ES2085832B1 (es) 1997-01-16
ES2085832A1 (es) 1996-06-01
JPH08183777A (ja) 1996-07-16
IL114236A0 (en) 1995-10-31
EP0693481A1 (en) 1996-01-24

Similar Documents

Publication Publication Date Title
HU199425B (en) Process for producing alpha-alkyl-/4-amino-3-quinolinyl/-methanols and 1-square brackets open 4-/aralkylamino/-3-quinolinyl square brackets closed -alkanones, as well as pharmaceutical compositions comprising such compounds as active ingredient
JPH0219363A (ja) イミダゾリジン誘導体
HU188353B (en) Process for producing new xanthine derivatives
EP1382333B1 (en) Use of beta 3 adrenergic receptor agonists in the treatment of dysuria
EP0000220B1 (de) Dihydrouracile, Verfahren zu ihrer Herstellung und sie enthaltende Arzneimittel
HU179170B (en) Process for producing phenethanolamine derivatives
US5342960A (en) Azomethines agonist compounds of the histamine H3 receptor for therapeutic use, pharmaceutical compositions acting as agonists of the said receptor and preparation process
HU184787B (en) Process for preparing alkoxy-benzyl-pyrido-pyrimidine derivatives
US4775673A (en) Substituted acylpiperazinoquinazolines and pharmaceutical compositions containing same
JP2690749B2 (ja) ベンズイミダゾール誘導体、その製造方法およびその医薬への応用
IL114236A (en) 5, 5-diphenylhydantoin derivatives, pharmaceutical compositions containing the same and a process for the preparation thereof
EP0139993A2 (de) Chinazolinderivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
US5635521A (en) Imidazolylmethyl-pyridines
FI57589C (fi) Foerfarande foer framstaellning av blodtrycket saenkande 6-substituerade 3-karbetoksihydrazinopyridaziner
US4221798A (en) Hypotensive 2-heterocycloamino-imidazolines
HU190710B (en) Process for preparing 2-/4-piperazinyl/-4-phenyl-quinazoline derivatives
EP0046290B1 (en) Synergistic combination of (r,s)alpha-fluoromethylhistidine and cimetidine as an anti-ulcer agent
SK152095A3 (en) Crystalline (+) l-hydrogentartrate, preparation method thereof, pharmaceutical composition containing its and its use
KR940001777B1 (ko) N-메톡시페닐에틸-n'-이미다졸릴페닐아미딘 유도체 및 그의 제조방법
HU180716B (en) Process for preparing substituted amino-alkyl-guanidines
EP0091045B1 (de) 2-Pyrrolin-3-carbonitril-Derivate, Verfahren zu deren Herstellung und diese enthaltende Arzneimittel
EP0127066A2 (en) Composition for treating asthma
KR940001776B1 (ko) N-메톡시페닐에틸-n'-이미다졸릴페닐아미딘 유도체 및 그의 제조방법
US4656172A (en) 1-[5-(3,4,5-Trimethoxy phenyl)-2,4-pentadienoyl]-4-(substituted carbonylmethyl)-piperazines having vasodilating activity
JPH0372480A (ja) キサンチン誘導体及びそれらを有効成分とする気管支拡張剤

Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
KB Patent renewed
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees