IL113532A - Process for the preparation of 4-amino-delta4-3-ketosteroids via 4-nitro-delta4-3-ketosteroids - Google Patents

Process for the preparation of 4-amino-delta4-3-ketosteroids via 4-nitro-delta4-3-ketosteroids

Info

Publication number
IL113532A
IL113532A IL11353295A IL11353295A IL113532A IL 113532 A IL113532 A IL 113532A IL 11353295 A IL11353295 A IL 11353295A IL 11353295 A IL11353295 A IL 11353295A IL 113532 A IL113532 A IL 113532A
Authority
IL
Israel
Prior art keywords
ketosteroids
delta4
hydrogen
alkyl
nitro
Prior art date
Application number
IL11353295A
Other languages
English (en)
Other versions
IL113532A0 (en
Original Assignee
Merrell Dow Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma
Publication of IL113532A0 publication Critical patent/IL113532A0/xx
Publication of IL113532A publication Critical patent/IL113532A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0005—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring the nitrogen atom being directly linked to the cyclopenta(a)hydro phenanthrene skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0005—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring the nitrogen atom being directly linked to the cyclopenta(a)hydro phenanthrene skeleton
    • C07J41/0011—Unsubstituted amino radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0066—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by a carbon atom forming part of an amide group

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
IL11353295A 1994-05-02 1995-04-28 Process for the preparation of 4-amino-delta4-3-ketosteroids via 4-nitro-delta4-3-ketosteroids IL113532A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US23143394A 1994-05-02 1994-05-02

Publications (2)

Publication Number Publication Date
IL113532A0 IL113532A0 (en) 1995-07-31
IL113532A true IL113532A (en) 2000-02-17

Family

ID=22869232

Family Applications (1)

Application Number Title Priority Date Filing Date
IL11353295A IL113532A (en) 1994-05-02 1995-04-28 Process for the preparation of 4-amino-delta4-3-ketosteroids via 4-nitro-delta4-3-ketosteroids

Country Status (18)

Country Link
US (4) US5750744A (fr)
EP (1) EP0758340B1 (fr)
JP (1) JPH09512547A (fr)
CN (1) CN1042540C (fr)
AT (1) ATE175419T1 (fr)
AU (1) AU686793B2 (fr)
CA (1) CA2188760A1 (fr)
DE (1) DE69507139T2 (fr)
DK (1) DK0758340T3 (fr)
ES (1) ES2128052T3 (fr)
FI (1) FI964410A (fr)
GR (1) GR3029433T3 (fr)
HU (1) HUT75523A (fr)
IL (1) IL113532A (fr)
NO (1) NO964627L (fr)
NZ (1) NZ283974A (fr)
WO (1) WO1995029932A1 (fr)
ZA (1) ZA953357B (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU4093799A (en) 1998-05-22 1999-12-13 Board Of Trustees Of The Leland Stanford Junior University Bifunctional molecules and therapies based thereon
US20030129186A1 (en) 2001-07-25 2003-07-10 Biomarin Pharmaceutical Inc. Compositions and methods for modulating blood-brain barrier transport
WO2004037843A2 (fr) * 2002-10-25 2004-05-06 Yissum Research Development Company Of The Hebrew University Of Jerusalem Composes steroides comprenant des groupes mimetiques de la superoxyde dismutase et des groupes donneurs d'oxyde nitrique, et leur utilisation dans la preparation de medicaments
PT1889198E (pt) 2005-04-28 2015-03-06 Proteus Digital Health Inc Sistema fármaco-informático
JP2009508494A (ja) 2005-09-16 2009-03-05 ラプトール ファーマシューティカル インコーポレイテッド Ｃｒを含むタンパク質に対して特異的な受容体−結合タンパク質（ｒａｐ）変異体を含む組成物およびその使用
PT2398500T (pt) 2009-02-20 2019-06-14 2 Bbb Medicines B V Sistema de entrega de medicamentos à base de glutationas
ES2942923T3 (es) 2009-05-06 2023-06-07 Laboratory Skin Care Inc Composiciones de administración dérmica que comprenden complejos de agente activo-partículas de fosfato de calcio y métodos de uso de las mismas

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB892620A (en) * 1957-07-20 1962-03-28 Syntex Sa Cyclopentanophenanthrene derivatives
US3014632A (en) * 1961-03-06 1961-12-26 American Can Co Divider
US3159622A (en) * 1963-03-22 1964-12-01 Searle & Co 17 alpha-(2-carboxyethyl)-17 belta-hydroxy-6-nitroandrost-4-en-3-one gamma-lactones
GB8503940D0 (en) * 1985-02-15 1985-03-20 Erba Farmitalia 4-substituted androstendione derivatives
US5120840A (en) * 1990-08-01 1992-06-09 Merrell Dow Pharmaceuticals Inc. 4-amino-4-ene-steroids and their use as 5α-reductase inhibitors
US5143909A (en) * 1991-03-19 1992-09-01 Merrell Dow Pharmaceuticals Inc. Aminosteroids in a method for inhibiting c17-20 lyase
NZ239141A (en) * 1990-08-01 1994-04-27 Merrell Dow Pharma 4-amino-delta-4,6-steroids; preparatory processes and pharmaceutical compositions
US5218110A (en) * 1990-08-01 1993-06-08 Merrell Dow Pharmaceuticals 4-amino-Δ4 -steroids and their use as 5α-reductase inhibitors

Also Published As

Publication number Publication date
ES2128052T3 (es) 1999-05-01
NZ283974A (en) 1998-02-26
EP0758340B1 (fr) 1999-01-07
FI964410A0 (fi) 1996-11-01
US5750744A (en) 1998-05-12
ZA953357B (en) 1996-01-17
GR3029433T3 (en) 1999-05-28
US5869475A (en) 1999-02-09
HUT75523A (en) 1997-05-28
AU2244995A (en) 1995-11-29
US5990328A (en) 1999-11-23
US5965550A (en) 1999-10-12
NO964627D0 (no) 1996-11-01
DK0758340T3 (da) 1999-08-30
WO1995029932A1 (fr) 1995-11-09
DE69507139D1 (de) 1999-02-18
CN1147258A (zh) 1997-04-09
HU9603035D0 (en) 1997-01-28
CA2188760A1 (fr) 1995-11-09
FI964410A (fi) 1996-11-01
IL113532A0 (en) 1995-07-31
AU686793B2 (en) 1998-02-12
DE69507139T2 (de) 1999-09-30
CN1042540C (zh) 1999-03-17
ATE175419T1 (de) 1999-01-15
EP0758340A1 (fr) 1997-02-19
JPH09512547A (ja) 1997-12-16
NO964627L (no) 1997-01-02

Similar Documents

Publication Publication Date Title
HUT73771A (en) Derivatives of valproic and 2-valproenoic acid amides and use anticonvulsants
MX9408969A (es) Composisciones farmaceuticas que comprenden microparticulas biodegradables y biocompatibles para el tratamiento de transtornos psicoticos, su uso y procedimiento para prepararlas.
HUT72192A (en) Compounds useful as sweeting agents, sweeting composition containing them and process for their preparation
NZ290757A (en) Delivery of nucleic acid into a cell
GR3023938T3 (en) 3',5'-ditertbutyl-4'-hydroxyflavones, method for their preparation and pharmaceutical compositions with an antioxidant and antivasoconstricting activity
GB9206648D0 (en) Chemical compounds
IL86139A (en) 17-(cyclopropylamino) androst-5-en-3 ol and pharmaceutical compositions containing them, useful as c17-20 lyase inhibitors
ZA984635B (en) Orally active iron (III) chelators.
IL113532A (en) Process for the preparation of 4-amino-delta4-3-ketosteroids via 4-nitro-delta4-3-ketosteroids
GR3026599T3 (en) Process for the preparation of taurocholic acids.
MY108259A (en) Liquid detergent composition
GB9220272D0 (en) Chemical compounds
ES8607935A1 (es) Un procedimiento de preparar un derivado de ariltio-piridi- nil-alcanol
GR852241B (fr)
IL116646A0 (en) Antifungal fusacandins
AU1032197A (en) New amino alcohol derivatives, processes for their production and pharmaceutical agents containing these compounds
ES8707939A1 (es) Procedimiento para preparar derivados de n-carboxialquil-2--oxo-3-diaril-5,6-triazinas
IL108155A0 (en) Pharmaceutical compositions containing 17 alphadihydroequilenin or an ester or salt thereof
MX9709823A (es) Acidos fenilboronicos 4-sustituidos como estabilizantes de enzimas.
GEP19971011B (en) process for production of Compounds for Combatting Psoriasis Disorders

Legal Events

Date Code Title Description
FF Patent granted
MM9K Patent not in force due to non-payment of renewal fees