IL112985A - Polyiodinated compounds their preparation and diagnostic compositions containing them - Google Patents
Polyiodinated compounds their preparation and diagnostic compositions containing themInfo
- Publication number
- IL112985A IL112985A IL11298595A IL11298595A IL112985A IL 112985 A IL112985 A IL 112985A IL 11298595 A IL11298595 A IL 11298595A IL 11298595 A IL11298595 A IL 11298595A IL 112985 A IL112985 A IL 112985A
- Authority
- IL
- Israel
- Prior art keywords
- ch2oh
- substd
- formula
- opt
- preparation
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 125000002947 alkylene group Chemical group 0.000 abstract 1
- 150000001414 amino alcohols Chemical class 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- CBOIHMRHGLHBPB-UHFFFAOYSA-N hydroxymethyl Chemical compound O[CH2] CBOIHMRHGLHBPB-UHFFFAOYSA-N 0.000 abstract 1
- 125000001997 phenyl group Chemical class [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/44—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having three double bonds between ring members or between ring members and non-ring members
- C07D207/444—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having three double bonds between ring members or between ring members and non-ring members having two doubly-bound oxygen atoms directly attached in positions 2 and 5
- C07D207/448—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having three double bonds between ring members or between ring members and non-ring members having two doubly-bound oxygen atoms directly attached in positions 2 and 5 with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms, e.g. maleimide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/04—X-ray contrast preparations
- A61K49/0433—X-ray contrast preparations containing an organic halogenated X-ray contrast-enhancing agent
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
- C07C215/02—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C215/04—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated
- C07C215/06—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and acyclic
- C07C215/12—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and acyclic the nitrogen atom of the amino group being further bound to hydrocarbon groups substituted by hydroxy groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/16—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
- C07C233/17—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
- C07C233/22—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom having the carbon atom of the carboxamide group bound to an acyclic carbon atom of a carbon skeleton containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/64—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings
- C07C233/67—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
- C07C233/68—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
- C07C233/69—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom of an acyclic saturated carbon skeleton
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
- Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
- Cephalosporin Compounds (AREA)
- Detergent Compositions (AREA)
- Hydrogenated Pyridines (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9403356A FR2717799B1 (fr) | 1994-03-22 | 1994-03-22 | Composés polyiodes : procédé de préparation ; composition de diagnostic. |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL112985A0 IL112985A0 (en) | 1995-06-29 |
| IL112985A true IL112985A (en) | 1999-10-28 |
Family
ID=9461306
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL11298595A IL112985A (en) | 1994-03-22 | 1995-03-14 | Polyiodinated compounds their preparation and diagnostic compositions containing them |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US5693311A (de) |
| EP (1) | EP0675105B1 (de) |
| JP (1) | JPH07316112A (de) |
| KR (1) | KR950032116A (de) |
| CN (1) | CN1112548A (de) |
| AT (1) | ATE174902T1 (de) |
| AU (1) | AU694164B2 (de) |
| BR (1) | BR9501157A (de) |
| CA (1) | CA2145035A1 (de) |
| CZ (1) | CZ69595A3 (de) |
| DE (1) | DE69506760T2 (de) |
| ES (1) | ES2126224T3 (de) |
| FI (1) | FI951323A7 (de) |
| FR (1) | FR2717799B1 (de) |
| HU (1) | HUT71893A (de) |
| IL (1) | IL112985A (de) |
| NO (1) | NO951072L (de) |
| NZ (1) | NZ270750A (de) |
| ZA (1) | ZA952265B (de) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2780287B3 (fr) * | 1998-06-30 | 2000-09-08 | Guerbet Sa | Derive polyhydroxyle du tetraiodoterephtalamide, son procede de preparation, son utilisation en radiologie et amino alcool intermediaire |
| US20060100127A1 (en) * | 2004-11-11 | 2006-05-11 | Meier Ingrid K | N,N-dialkylpolyhydroxyalkylamines |
| JP2011500533A (ja) | 2007-10-12 | 2011-01-06 | ジーイー・ヘルスケア・アクスイェ・セルスカプ | 造影剤 |
| DE102007058220A1 (de) | 2007-12-03 | 2009-06-04 | Bayer Schering Pharma Aktiengesellschaft | Dimere macrocyclisch substituierte Benzolderivate |
| CN103086915A (zh) * | 2011-10-31 | 2013-05-08 | 上海海神化学生物科技有限公司 | 制备3,5-二取代-2,4,6-三碘代芳香胺类化合物的碘化方法 |
| WO2017165841A1 (en) | 2016-03-25 | 2017-09-28 | Nanoprobes, Inc. | Iodine-based particles |
| US10342232B1 (en) | 2018-10-24 | 2019-07-09 | The United States Of America As Represented By The Secretary Of The Navy | Iodinated polymers for biological agent defeat |
| CN114262279B (zh) * | 2021-12-30 | 2022-12-16 | 上海汇禾医疗科技有限公司 | 一种x射线可显影分子、栓塞微球及其制备方法 |
| CN116924929A (zh) * | 2022-07-08 | 2023-10-24 | 重庆圣华曦药业股份有限公司 | 一种碘比醇异构体的合成方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH385423A (de) * | 1958-12-03 | 1964-12-15 | Chemie Linz Ag | Verwendung polyjodierter Benzoesäureabkömmlinge als Röntgenkontrastmittel |
| DE2909439A1 (de) * | 1979-03-08 | 1980-09-18 | Schering Ag | Neue nichtionische roentgenkontrastmittel |
| IT1245853B (it) * | 1990-11-16 | 1994-10-25 | Bracco Spa | 1,3-bis(3-(mono o poliidrossi)acilamino-5-(mono o poliidrossi-alchil) aminocarbonil-2,4,6-triiodo-benzoil-amino)-idrossi- o idrossi-alchil- propani, loro metodo di preparazione e mezzi di contrasto roentgenografici che li contengono |
| FR2687669B1 (fr) * | 1992-02-24 | 1997-12-19 | Guerbet Sa | Composes utilisables dans des produits de contraste pour la radiographie. |
-
1994
- 1994-03-22 FR FR9403356A patent/FR2717799B1/fr not_active Expired - Fee Related
-
1995
- 1995-03-14 IL IL11298595A patent/IL112985A/xx not_active IP Right Cessation
- 1995-03-17 US US08/406,304 patent/US5693311A/en not_active Expired - Lifetime
- 1995-03-17 CZ CZ95695A patent/CZ69595A3/cs unknown
- 1995-03-17 JP JP7058753A patent/JPH07316112A/ja active Pending
- 1995-03-20 DE DE69506760T patent/DE69506760T2/de not_active Expired - Fee Related
- 1995-03-20 ES ES95400611T patent/ES2126224T3/es not_active Expired - Lifetime
- 1995-03-20 NZ NZ270750A patent/NZ270750A/en unknown
- 1995-03-20 EP EP95400611A patent/EP0675105B1/de not_active Expired - Lifetime
- 1995-03-20 ZA ZA952265A patent/ZA952265B/xx unknown
- 1995-03-20 AT AT95400611T patent/ATE174902T1/de not_active IP Right Cessation
- 1995-03-20 CA CA002145035A patent/CA2145035A1/en not_active Abandoned
- 1995-03-21 NO NO951072A patent/NO951072L/no not_active Application Discontinuation
- 1995-03-21 HU HU9500823A patent/HUT71893A/hu unknown
- 1995-03-21 AU AU14990/95A patent/AU694164B2/en not_active Ceased
- 1995-03-21 FI FI951323A patent/FI951323A7/fi unknown
- 1995-03-21 CN CN95102715A patent/CN1112548A/zh active Pending
- 1995-03-22 KR KR1019950006139A patent/KR950032116A/ko not_active Withdrawn
- 1995-03-22 BR BR9501157A patent/BR9501157A/pt not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| FR2717799B1 (fr) | 1996-07-19 |
| ZA952265B (en) | 1996-09-20 |
| US5693311A (en) | 1997-12-02 |
| AU694164B2 (en) | 1998-07-16 |
| BR9501157A (pt) | 1996-06-04 |
| AU1499095A (en) | 1995-09-28 |
| IL112985A0 (en) | 1995-06-29 |
| ES2126224T3 (es) | 1999-03-16 |
| FR2717799A1 (fr) | 1995-09-29 |
| CA2145035A1 (en) | 1995-09-23 |
| CZ69595A3 (en) | 1995-11-15 |
| NO951072D0 (no) | 1995-03-21 |
| DE69506760T2 (de) | 1999-09-02 |
| DE69506760D1 (de) | 1999-02-04 |
| ATE174902T1 (de) | 1999-01-15 |
| CN1112548A (zh) | 1995-11-29 |
| JPH07316112A (ja) | 1995-12-05 |
| EP0675105B1 (de) | 1998-12-23 |
| NZ270750A (en) | 1996-05-28 |
| NO951072L (no) | 1995-09-25 |
| HUT71893A (en) | 1996-02-28 |
| FI951323A0 (fi) | 1995-03-21 |
| HU9500823D0 (en) | 1995-05-29 |
| FI951323A7 (fi) | 1995-09-23 |
| KR950032116A (ko) | 1995-12-20 |
| EP0675105A1 (de) | 1995-10-04 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FF | Patent granted | ||
| KB | Patent renewed | ||
| MM9K | Patent not in force due to non-payment of renewal fees |