IL112969A - Pharmaceutical compositions for the treatment of cancer comprising allogenic lymphocytes or their combination with a t-cell activator - Google Patents
Pharmaceutical compositions for the treatment of cancer comprising allogenic lymphocytes or their combination with a t-cell activatorInfo
- Publication number
- IL112969A IL112969A IL11296995A IL11296995A IL112969A IL 112969 A IL112969 A IL 112969A IL 11296995 A IL11296995 A IL 11296995A IL 11296995 A IL11296995 A IL 11296995A IL 112969 A IL112969 A IL 112969A
- Authority
- IL
- Israel
- Prior art keywords
- patient
- cells
- cell
- lymphocytes
- allogeneic
- Prior art date
Links
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- A61K38/19—Cytokines; Lymphokines; Interferons
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- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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- A61K39/461—Cellular immunotherapy characterised by the cell type used
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- A61K39/462—Cellular immunotherapy characterized by the effect or the function of the cells
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- A61K39/464—Cellular immunotherapy characterised by the antigen targeted or presented
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- A61K39/46434—Antigens related to induction of tolerance to non-self
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- A—HUMAN NECESSITIES
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- A61K39/46—Cellular immunotherapy
- A61K39/464—Cellular immunotherapy characterised by the antigen targeted or presented
- A61K39/4643—Vertebrate antigens
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0636—T lymphocytes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K2035/124—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells the cells being hematopoietic, bone marrow derived or blood cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/20—Cytokines; Chemokines
- C12N2501/23—Interleukins [IL]
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Cell Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Biomedical Technology (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Oncology (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Hematology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Hospice & Palliative Care (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US21494494A | 1994-03-17 | 1994-03-17 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL112969A0 IL112969A0 (en) | 1995-06-29 |
| IL112969A true IL112969A (en) | 2001-05-20 |
Family
ID=22801017
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL11296995A IL112969A (en) | 1994-03-17 | 1995-03-13 | Pharmaceutical compositions for the treatment of cancer comprising allogenic lymphocytes or their combination with a t-cell activator |
Country Status (9)
| Country | Link |
|---|---|
| US (3) | US5843435A (fr) |
| EP (1) | EP0750505B1 (fr) |
| JP (1) | JPH09510456A (fr) |
| AU (1) | AU2100695A (fr) |
| CA (1) | CA2184352A1 (fr) |
| DE (1) | DE69533189T2 (fr) |
| ES (1) | ES2224122T3 (fr) |
| IL (1) | IL112969A (fr) |
| WO (1) | WO1995024910A1 (fr) |
Families Citing this family (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL112969A (en) * | 1994-03-17 | 2001-05-20 | Baxter Int | Pharmaceutical compositions for the treatment of cancer comprising allogenic lymphocytes or their combination with a t-cell activator |
| WO1996037208A1 (fr) * | 1995-05-25 | 1996-11-28 | Baxter International Inc. | Therapie cellulaire allogenique anticancereuse suivant une transplantation de cellules souches allogeniques |
| US5800539A (en) * | 1995-11-08 | 1998-09-01 | Emory University | Method of allogeneic hematopoietic stem cell transplantation without graft failure or graft vs. host disease |
| WO1997026328A1 (fr) * | 1996-01-17 | 1997-07-24 | Imperial College Innovations Limited | Immunotherapie utilisant des lymphocytes t cytotoxiques (ctl) |
| US6213127B1 (en) | 1996-07-29 | 2001-04-10 | Emory University | Methods for treating cancer using allogeneic lymphocytes without graft vs host disease activity |
| IL129573A0 (en) * | 1996-11-15 | 2000-02-29 | Baxter Int | Conditioning for allogeneic stem cell transplantation |
| US6428782B1 (en) * | 1997-05-23 | 2002-08-06 | Hadasit Medical Research Services And Development Ltd. | Non-myeloablative tolerogenic treatment |
| EP1037643B1 (fr) * | 1997-10-10 | 2003-12-03 | Meyer Pharmaceuticals, LLC | Immunotherapie du cancer utilisant des cellules allostimulees dans une strategie de greffe sequentielle multiple |
| US20040033230A1 (en) * | 1997-12-24 | 2004-02-19 | Corixa Corporation | Compositions and methods for the therapy and diagnosis of breast cancer |
| US7598226B2 (en) | 1998-12-28 | 2009-10-06 | Corixa Corporation | Compositions and methods for the therapy and diagnosis of breast cancer |
| US6969518B2 (en) * | 1998-12-28 | 2005-11-29 | Corixa Corporation | Compositions and methods for the therapy and diagnosis of breast cancer |
| WO2001040269A2 (fr) * | 1999-11-30 | 2001-06-07 | Corixa Corporation | Compositions et methodes destinees au traitement et au diagnostic du cancer du sein |
| US7541184B2 (en) | 2000-02-24 | 2009-06-02 | Invitrogen Corporation | Activation and expansion of cells |
| US7572631B2 (en) | 2000-02-24 | 2009-08-11 | Invitrogen Corporation | Activation and expansion of T cells |
| JP4917201B2 (ja) * | 2000-12-04 | 2012-04-18 | 株式会社リンフォテック | 臍帯血移植後の腫瘍および各種感染症の予防・治療用製剤、臍帯血移植後の移植臍帯血幹細胞の生着促進用製剤、臍帯血移植後の腫瘍および各種感染症の予防・治療用製剤ならびに臍帯血移植後の移植臍帯血幹細胞の生着促進用製剤の製造方法。 |
| KR20020060643A (ko) * | 2002-06-04 | 2002-07-18 | 김진경 | 타인의 면역시스템을 이용하는 암의 치료 방법 |
| US20050084967A1 (en) | 2002-06-28 | 2005-04-21 | Xcyte Therapies, Inc. | Compositions and methods for eliminating undesired subpopulations of T cells in patients with immunological defects related to autoimmunity and organ or hematopoietic stem cell transplantation |
| US20040175373A1 (en) * | 2002-06-28 | 2004-09-09 | Xcyte Therapies, Inc. | Compositions and methods for eliminating undesired subpopulations of T cells in patients with immunological defects related to autoimmunity and organ or hematopoietic stem cell transplantation |
| WO2004003142A2 (fr) * | 2002-06-28 | 2004-01-08 | Xcyte Therapies, Inc. | Compositions et techniques permettant de restaurer le repertoire immunologique de patients qui presente des defauts immunologiques lies a l'auto-immunite et a un organe ou a une transplantation de cellules souche hematopoietiques multipotentes |
| WO2005021734A2 (fr) * | 2003-09-02 | 2005-03-10 | University Of Massachussets | Generation de chimerisme hematopoietique et induction de tolerance centrale |
| JP2007522246A (ja) * | 2004-02-12 | 2007-08-09 | ネクター セラピューティクス | インターロイキン−１３拮抗剤粉末剤、スプレードライ粒子、及び方法 |
| EP1755685A4 (fr) * | 2004-05-28 | 2008-11-12 | Mayo Foundation | Methodes pour une transplantation de cellules souches autologues |
| US9155789B2 (en) * | 2005-04-25 | 2015-10-13 | New York University | Use of allogenic or syngenic major histocompatibility complex (MHC) molecules as universal adjuvants for vaccines against neoplastic disease, infection and autoimmune disease |
| PT2511301T (pt) | 2006-08-04 | 2018-03-08 | Medimmune Ltd | Anticorpos humanos para erbb2 |
| DK2068874T3 (da) | 2006-08-07 | 2015-04-27 | Abbvie Biotherapeutics Inc | Fremgangsmåder til behandling af multiple myelom med anvendelse af kombinationsterapier baseret på anti-cs1 antistoffer |
| EP2068930B1 (fr) | 2006-08-07 | 2012-09-19 | Abbott Biotherapeutics Corp. | Compositions et méthodes utilisant des anticorps anti-cs1 pour traiter un myélome multiple |
| CA2668673A1 (fr) * | 2006-11-08 | 2008-05-22 | Aldagen, Inc. | Methodes de greffe amelioree apres une transplantation de cellules souches |
| EP2089041A2 (fr) * | 2006-11-08 | 2009-08-19 | Aldagen, Inc. | Méthodes d'utilisation de cellules aldhbr pour compléter une transplantation de cellules souches |
| KR20120054018A (ko) * | 2009-08-17 | 2012-05-29 | 도꾜 다이가꾸 | 일과성 생착 ｃｔｌ을 포함하는 의약품 조성물 |
| WO2013093919A2 (fr) | 2011-12-22 | 2013-06-27 | Yeda Research And Development Co. Ltd. | Polythérapie mise en oeuvre pour obtenir une prise de greffe stable et à long terme au moyen de protocoles spécifiques d'appauvrissement des lymphocytes t/b |
| US10365280B2 (en) | 2014-10-02 | 2019-07-30 | Dana-Farber Cancer Institute, Inc. | Compositions and methods for treating malignancies |
| US10302644B2 (en) | 2014-11-04 | 2019-05-28 | Dana-Farber Cancer Institute, Inc. | Compositions and methods for treating multiple myeloma |
| TWI848906B (zh) | 2017-03-15 | 2024-07-21 | 美商歐卡生物系統公司 | 用於造血幹細胞移植的組合物及方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4690915A (en) * | 1985-08-08 | 1987-09-01 | The United States Of America As Represented By The Department Of Health And Human Services | Adoptive immunotherapy as a treatment modality in humans |
| US4861589A (en) * | 1987-03-23 | 1989-08-29 | Trustees Of Boston University | Method for therapeutically treating abnormal cells expressing a major histocompatibility complex class II antigen using cytolytic inducer T4 cells |
| US5126132A (en) * | 1989-08-21 | 1992-06-30 | The United States Of America As Represented By The Department Of Health And Human Services | Tumor infiltrating lymphocytes as a treatment modality for human cancer |
| JPH07102131B2 (ja) * | 1991-07-15 | 1995-11-08 | 日本石油株式会社 | ヒトリンパ球の癌細胞に対する傷害活性を高める方法 |
| IL112969A (en) * | 1994-03-17 | 2001-05-20 | Baxter Int | Pharmaceutical compositions for the treatment of cancer comprising allogenic lymphocytes or their combination with a t-cell activator |
-
1995
- 1995-03-13 IL IL11296995A patent/IL112969A/en not_active IP Right Cessation
- 1995-03-16 WO PCT/US1995/003303 patent/WO1995024910A1/fr active IP Right Grant
- 1995-03-16 JP JP7524180A patent/JPH09510456A/ja active Pending
- 1995-03-16 CA CA002184352A patent/CA2184352A1/fr not_active Abandoned
- 1995-03-16 DE DE69533189T patent/DE69533189T2/de not_active Expired - Lifetime
- 1995-03-16 AU AU21006/95A patent/AU2100695A/en not_active Abandoned
- 1995-03-16 ES ES95913730T patent/ES2224122T3/es not_active Expired - Lifetime
- 1995-03-16 EP EP95913730A patent/EP0750505B1/fr not_active Expired - Lifetime
- 1995-03-16 US US08/714,144 patent/US5843435A/en not_active Expired - Lifetime
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1996
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2001
- 2001-12-03 US US10/005,747 patent/US20020176850A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| DE69533189D1 (de) | 2004-07-29 |
| JPH09510456A (ja) | 1997-10-21 |
| AU2100695A (en) | 1995-10-03 |
| IL112969A0 (en) | 1995-06-29 |
| CA2184352A1 (fr) | 1995-09-21 |
| DE69533189T2 (de) | 2005-07-21 |
| US5843435A (en) | 1998-12-01 |
| US5928639A (en) | 1999-07-27 |
| US20020176850A1 (en) | 2002-11-28 |
| WO1995024910A1 (fr) | 1995-09-21 |
| MX9604099A (es) | 1997-09-30 |
| ES2224122T3 (es) | 2005-03-01 |
| EP0750505A1 (fr) | 1997-01-02 |
| EP0750505B1 (fr) | 2004-06-23 |
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