IL112047A0 - Methods of inhibiting myeloperoxidase activity - Google Patents
Methods of inhibiting myeloperoxidase activityInfo
- Publication number
- IL112047A0 IL112047A0 IL11204794A IL11204794A IL112047A0 IL 112047 A0 IL112047 A0 IL 112047A0 IL 11204794 A IL11204794 A IL 11204794A IL 11204794 A IL11204794 A IL 11204794A IL 112047 A0 IL112047 A0 IL 112047A0
- Authority
- IL
- Israel
- Prior art keywords
- methods
- myeloperoxidase activity
- inhibiting myeloperoxidase
- inhibiting
- activity
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/4025—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil not condensed and containing further heterocyclic rings, e.g. cromakalim
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/4535—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a heterocyclic ring having sulfur as a ring hetero atom, e.g. pizotifen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Transplantation (AREA)
- Urology & Nephrology (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/171,330 US5708009A (en) | 1993-12-21 | 1993-12-21 | Methods of inhibiting myeloperoxidase activity |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL112047A0 true IL112047A0 (en) | 1995-03-15 |
Family
ID=22623358
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL11204794A IL112047A0 (en) | 1993-12-21 | 1994-12-19 | Methods of inhibiting myeloperoxidase activity |
Country Status (16)
| Country | Link |
|---|---|
| US (2) | US5708009A (de) |
| EP (1) | EP0664125A1 (de) |
| JP (1) | JPH07242546A (de) |
| KR (1) | KR950016743A (de) |
| CN (1) | CN1109884A (de) |
| AU (1) | AU8154394A (de) |
| CA (1) | CA2138513A1 (de) |
| CZ (1) | CZ322794A3 (de) |
| HU (1) | HUT72314A (de) |
| IL (1) | IL112047A0 (de) |
| NO (1) | NO944926L (de) |
| NZ (1) | NZ270184A (de) |
| PH (1) | PH31556A (de) |
| RU (1) | RU94044489A (de) |
| TW (1) | TW272939B (de) |
| ZA (1) | ZA9410096B (de) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6515009B1 (en) | 1991-09-27 | 2003-02-04 | Neorx Corporation | Therapeutic inhibitor of vascular smooth muscle cells |
| US5811447A (en) | 1993-01-28 | 1998-09-22 | Neorx Corporation | Therapeutic inhibitor of vascular smooth muscle cells |
| US6491938B2 (en) | 1993-05-13 | 2002-12-10 | Neorx Corporation | Therapeutic inhibitor of vascular smooth muscle cells |
| US5492927A (en) * | 1993-12-21 | 1996-02-20 | Eli Lilly And Company | Non-peptide tachykinin receptor antagonists to treat allergy |
| US5434166A (en) * | 1994-08-22 | 1995-07-18 | Eli Lilly And Company | Methods of inhibiting demyelinating and desmyelinating diseases |
| WO1996024356A1 (en) * | 1995-02-06 | 1996-08-15 | Eli Lilly And Company | Methods of inhibiting effects of il-6 |
| TW442286B (en) * | 1996-02-28 | 2001-06-23 | Pfizer | New therapeutic uses of estrogen agonists |
| US5719190A (en) * | 1996-02-28 | 1998-02-17 | Pfizer Inc. | Inhibition of myeloperoxidase activity |
| IL120266A (en) | 1996-02-28 | 2005-05-17 | Pfizer | Use of estrogen antagonists and estrogen agonists in the preparation of medicaments for inhibiting pathological conditions |
| US6117911A (en) | 1997-04-11 | 2000-09-12 | Neorx Corporation | Compounds and therapies for the prevention of vascular and non-vascular pathologies |
| AU4084599A (en) * | 1998-05-18 | 1999-12-06 | Oklahoma Medical Research Foundation | Resveratrol inhibition of myeloperoxidase |
| US6630453B1 (en) | 1999-05-04 | 2003-10-07 | Strakan Limited | Androgen derivatives and uses thereof |
| GB2362101A (en) * | 2000-05-12 | 2001-11-14 | Astrazeneca Ab | Treatment of chronic obstructive pulmonary disease |
| CA2512021A1 (en) * | 2003-01-06 | 2004-07-29 | Wyeth | The use of estrogen receptor alpha modulators for the treatment of multiple sclerosis |
| DE602005020755D1 (de) * | 2004-03-05 | 2010-06-02 | Univ Illinois | Peptidträger für die verabreichung von arzneimitteln |
| UY30267A1 (es) * | 2006-04-13 | 2007-11-30 | Astrazeneca Ab | Nuevos derivados de la tioxantina , composiciones farmacéuticas que los contienen, procedimientos de preparacion y aplicaciones |
| US20090286813A1 (en) * | 2006-04-13 | 2009-11-19 | Astrazeneca Ab | Thioxanthine Derivatives and Their Use as Inhibitors of MPO |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4133814A (en) * | 1975-10-28 | 1979-01-09 | Eli Lilly And Company | 2-Phenyl-3-aroylbenzothiophenes useful as antifertility agents |
| US4380635A (en) * | 1981-04-03 | 1983-04-19 | Eli Lilly And Company | Synthesis of acylated benzothiophenes |
| US4418068A (en) * | 1981-04-03 | 1983-11-29 | Eli Lilly And Company | Antiestrogenic and antiandrugenic benzothiophenes |
| US5075321A (en) * | 1987-03-24 | 1991-12-24 | University Of Pennsylvania | Methods of treating diseases characterized by interactions of IgG-containing immune complexes with macrophage Fc receptors using antiestrogenic benzothiophenes |
| JP3157882B2 (ja) * | 1991-11-15 | 2001-04-16 | 帝国臓器製薬株式会社 | 新規なベンゾチオフエン誘導体 |
| AU672182B2 (en) * | 1991-11-27 | 1996-09-26 | Novo Nordisk A/S | Piperidine derivatives and their use in treating psychosis |
-
1993
- 1993-12-21 US US08/171,330 patent/US5708009A/en not_active Expired - Fee Related
-
1994
- 1994-12-19 CA CA002138513A patent/CA2138513A1/en not_active Abandoned
- 1994-12-19 HU HU9403677A patent/HUT72314A/hu unknown
- 1994-12-19 CN CN94119743A patent/CN1109884A/zh active Pending
- 1994-12-19 AU AU81543/94A patent/AU8154394A/en not_active Abandoned
- 1994-12-19 JP JP6314565A patent/JPH07242546A/ja active Pending
- 1994-12-19 EP EP94309468A patent/EP0664125A1/de not_active Withdrawn
- 1994-12-19 IL IL11204794A patent/IL112047A0/xx unknown
- 1994-12-19 KR KR1019940034934A patent/KR950016743A/ko not_active Application Discontinuation
- 1994-12-19 TW TW083111852A patent/TW272939B/zh active
- 1994-12-19 ZA ZA9410096A patent/ZA9410096B/xx unknown
- 1994-12-19 PH PH49578A patent/PH31556A/en unknown
- 1994-12-19 CZ CZ943227A patent/CZ322794A3/cs unknown
- 1994-12-19 NO NO944926A patent/NO944926L/no unknown
- 1994-12-19 RU RU94044489/14A patent/RU94044489A/ru unknown
- 1994-12-19 NZ NZ270184A patent/NZ270184A/xx unknown
-
1995
- 1995-05-18 US US08/443,840 patent/US5708010A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| JPH07242546A (ja) | 1995-09-19 |
| NZ270184A (en) | 1999-07-29 |
| PH31556A (en) | 1998-11-03 |
| CN1109884A (zh) | 1995-10-11 |
| US5708009A (en) | 1998-01-13 |
| NO944926L (no) | 1995-06-22 |
| EP0664125A1 (de) | 1995-07-26 |
| RU94044489A (ru) | 1996-10-20 |
| ZA9410096B (en) | 1996-06-19 |
| CA2138513A1 (en) | 1995-06-22 |
| CZ322794A3 (en) | 1995-08-16 |
| HU9403677D0 (en) | 1995-02-28 |
| AU8154394A (en) | 1995-06-29 |
| KR950016743A (ko) | 1995-07-20 |
| TW272939B (de) | 1996-03-21 |
| US5708010A (en) | 1998-01-13 |
| HUT72314A (en) | 1996-04-29 |
| NO944926D0 (no) | 1994-12-19 |
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