IL111375A - N-substituted azabicycloalkane derivatives and pharmaceutical compositions containing them - Google Patents
N-substituted azabicycloalkane derivatives and pharmaceutical compositions containing themInfo
- Publication number
- IL111375A IL111375A IL111375A IL11137594A IL111375A IL 111375 A IL111375 A IL 111375A IL 111375 A IL111375 A IL 111375A IL 11137594 A IL11137594 A IL 11137594A IL 111375 A IL111375 A IL 111375A
- Authority
- IL
- Israel
- Prior art keywords
- group
- atom
- hydroxyl
- amino
- alkyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Psychiatry (AREA)
- Anesthesiology (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE4338396A DE4338396A1 (de) | 1993-11-10 | 1993-11-10 | N-Substituierte Azabicycloalkan-Derivate, ihre Herstellung und Verwendung |
Publications (2)
Publication Number | Publication Date |
---|---|
IL111375A0 IL111375A0 (en) | 1994-12-29 |
IL111375A true IL111375A (en) | 1997-06-10 |
Family
ID=6502267
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL111375A IL111375A (en) | 1993-11-10 | 1994-10-24 | N-substituted azabicycloalkane derivatives and pharmaceutical compositions containing them |
Country Status (11)
Country | Link |
---|---|
US (2) | US5908844A (de) |
EP (1) | EP0728136A1 (de) |
JP (1) | JPH09505283A (de) |
AU (1) | AU681204B2 (de) |
BR (1) | BR9408029A (de) |
CA (1) | CA2175683A1 (de) |
DE (1) | DE4338396A1 (de) |
FI (1) | FI961977A0 (de) |
HU (1) | HUT74691A (de) |
IL (1) | IL111375A (de) |
WO (1) | WO1995013279A1 (de) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TWI274750B (en) * | 1999-01-12 | 2007-03-01 | Abbott Gmbh & Co Kg | Triazole compounds showing high affinity to dopamine D3 receptor and pharmaceutical composition comprising the same |
US7963904B2 (en) * | 2000-09-29 | 2011-06-21 | Delisle Clarence A | Method and device for treating body ailments |
SE0100326D0 (sv) | 2001-02-02 | 2001-02-02 | Astrazeneca Ab | New compounds |
ATE382623T1 (de) | 2004-06-09 | 2008-01-15 | Hoffmann La Roche | Octahydropyrrolo(3,4-c)pyrrolderivate und deren verwendung als antivirale mitteln |
US7665658B2 (en) | 2005-06-07 | 2010-02-23 | First Data Corporation | Dynamic aggregation of payment transactions |
EA200870404A1 (ru) | 2006-04-03 | 2009-04-28 | Глэксо Груп Лимитед | Производные азабицикло[3.1.0.]гексила в качестве модуляторов рецепторов допамина d3 |
EP2007751B1 (de) | 2006-04-03 | 2013-08-21 | Glaxo Group Limited | Azabicyclo[3.1.0]hexylderivate als modulatoren von dopamin-d3-rezeptoren |
EP2010523A1 (de) * | 2006-04-27 | 2009-01-07 | Glaxo Group Limited | Als modulatoren für dopamin-d3-rezeptoren geeignete spiroverbindungen |
GB0719235D0 (en) * | 2007-10-02 | 2007-11-14 | Glaxo Group Ltd | Novel compounds |
EP3978497A4 (de) * | 2019-05-30 | 2022-07-13 | Shanghai Institute of Materia Medica, Chinese Academy of Sciences | Kondensierte ringverbindung, herstellungsverfahren dafür und verwendung davon |
CN118359619A (zh) * | 2023-01-18 | 2024-07-19 | 苏州旺山旺水生物医药股份有限公司 | 一种抗抑郁化合物的盐、其制备方法、包含其的药物组合物及其用途 |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3155668A (en) * | 1960-04-11 | 1964-11-03 | Sterling Drug Inc | 1-[3-, 2-, and 1-indolyl)-lower-alkyl]-tertiary amines and intermediates therefor |
GB1383409A (en) * | 1972-09-09 | 1974-02-12 | Pfizer Ltd | Derivatives of 2-amino- and 4-amino-quinazoline and pharmaceutical compositions containing them |
US4443451A (en) * | 1981-07-15 | 1984-04-17 | Janssen Pharmaceutica N.V. | Bicyclic pyrimidin-5-one derivatives |
US4548938A (en) * | 1981-07-15 | 1985-10-22 | Janssen Pharmaceutica N.V. | 5-H-1,3,4-thiadiazolo[3,2-a]pyrimidin-5-one compounds |
US4804663A (en) * | 1985-03-27 | 1989-02-14 | Janssen Pharmaceutica N.V. | 3-piperidinyl-substituted 1,2-benzisoxazoles and 1,2-benzisothiazoles |
US5049564A (en) * | 1989-11-17 | 1991-09-17 | Abbott Laboratories | 5-HT selective agents |
US5532243A (en) * | 1992-02-14 | 1996-07-02 | The Dupont Merck Pharmaceutical Company | Antipsychotic nitrogen-containing bicyclic compounds |
DE4243287A1 (de) * | 1992-06-19 | 1993-12-23 | Basf Ag | N-Substituierte Azabicycloheptan-Derivate, ihre Herstellung und Verwendung |
-
1993
- 1993-11-10 DE DE4338396A patent/DE4338396A1/de not_active Withdrawn
-
1994
- 1994-10-24 IL IL111375A patent/IL111375A/xx not_active IP Right Cessation
- 1994-10-31 CA CA002175683A patent/CA2175683A1/en not_active Abandoned
- 1994-10-31 BR BR9408029A patent/BR9408029A/pt not_active Application Discontinuation
- 1994-10-31 US US08/640,751 patent/US5908844A/en not_active Expired - Lifetime
- 1994-10-31 AU AU81054/94A patent/AU681204B2/en not_active Ceased
- 1994-10-31 HU HU9601245A patent/HUT74691A/hu unknown
- 1994-10-31 JP JP7513562A patent/JPH09505283A/ja active Pending
- 1994-10-31 WO PCT/EP1994/003583 patent/WO1995013279A1/de not_active Application Discontinuation
- 1994-10-31 EP EP95900102A patent/EP0728136A1/de not_active Withdrawn
-
1996
- 1996-05-09 FI FI961977A patent/FI961977A0/fi unknown
-
1999
- 1999-02-01 US US09/241,299 patent/US6096755A/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
HU9601245D0 (en) | 1996-07-29 |
FI961977A (fi) | 1996-05-09 |
IL111375A0 (en) | 1994-12-29 |
DE4338396A1 (de) | 1995-05-11 |
CA2175683A1 (en) | 1995-05-18 |
BR9408029A (pt) | 1996-12-17 |
HUT74691A (en) | 1997-01-28 |
US6096755A (en) | 2000-08-01 |
WO1995013279A1 (de) | 1995-05-18 |
US5908844A (en) | 1999-06-01 |
AU681204B2 (en) | 1997-08-21 |
FI961977A0 (fi) | 1996-05-09 |
AU8105494A (en) | 1995-05-29 |
JPH09505283A (ja) | 1997-05-27 |
EP0728136A1 (de) | 1996-08-28 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FF | Patent granted | ||
KB | Patent renewed | ||
RH | Patent void |