IL110967A0 - Substituted tetronic acids useful for treating hiv and other retroviruses - Google Patents

Substituted tetronic acids useful for treating hiv and other retroviruses

Info

Publication number
IL110967A0
IL110967A0 IL11096794A IL11096794A IL110967A0 IL 110967 A0 IL110967 A0 IL 110967A0 IL 11096794 A IL11096794 A IL 11096794A IL 11096794 A IL11096794 A IL 11096794A IL 110967 A0 IL110967 A0 IL 110967A0
Authority
IL
Israel
Prior art keywords
retroviruses
treating hiv
acids useful
tetronic acids
substituted tetronic
Prior art date
Application number
IL11096794A
Other languages
English (en)
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of IL110967A0 publication Critical patent/IL110967A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/60—Two oxygen atoms, e.g. succinic anhydride
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/94—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom spiro-condensed with carbocyclic rings or ring systems, e.g. griseofulvins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/10—Spiro-condensed systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IL11096794A 1993-09-17 1994-09-14 Substituted tetronic acids useful for treating hiv and other retroviruses IL110967A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US12302993A 1993-09-17 1993-09-17
US23882094A 1994-05-06 1994-05-06

Publications (1)

Publication Number Publication Date
IL110967A0 true IL110967A0 (en) 1994-11-28

Family

ID=26821148

Family Applications (1)

Application Number Title Priority Date Filing Date
IL11096794A IL110967A0 (en) 1993-09-17 1994-09-14 Substituted tetronic acids useful for treating hiv and other retroviruses

Country Status (8)

Country Link
US (1) US5977169A (zh)
EP (1) EP0720607A1 (zh)
JP (1) JPH09502713A (zh)
AU (1) AU7636894A (zh)
CA (1) CA2168757A1 (zh)
IL (1) IL110967A0 (zh)
TW (1) TW354294B (zh)
WO (1) WO1995007901A1 (zh)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU5417696A (en) * 1995-03-20 1996-10-08 Upjohn Company, The Substituted tetronic acids useful for treating hiv and other retroviruses
UA56992C2 (uk) * 1995-05-08 2003-06-16 Фармація Енд Апджон Компані <font face="Symbol">a</font>-ПІРИМІДИНТІОАЛКІЛЗАМІЩЕНІ ТА <font face="Symbol">a</font>-ПІРИМІДИНОКСОАЛКІЛЗАМІЩЕНІ СПОЛУКИ
RS52139B (en) * 2001-06-13 2012-08-31 Magnachem International Laboratories Inc. LACTON FORMULATIONS AND PROCEDURE FOR THEIR USE
CA2504886C (en) * 2002-11-05 2011-07-05 Magnachem International Laboratories, Inc. Synthetic lactone formulations and method of use
WO2005102315A1 (en) 2004-04-23 2005-11-03 Magnachem International Laboratories, Inc. Synthetic lactone formulations for pain control
DE102006039912A1 (de) * 2006-08-25 2008-03-20 Bayer Healthcare Ag Substituierte Spirotetronsäuren und ihre Verwendung
DE102006059319A1 (de) * 2006-12-15 2008-06-19 Bayer Healthcare Ag Substituierte Aminofuranone und ihre Verwendung
EP2350645A2 (en) * 2008-10-24 2011-08-03 Magnachem International Laboratories, Inc. Method for screening for compounds selectively interacting with rad9
CN111195246A (zh) * 2018-11-16 2020-05-26 广西医科大学 聚醚类抗生素k-41b、k-41a在制备治疗或预防艾滋病毒药物中的应用

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA852614B (en) * 1985-05-17 1986-10-09 Takeda Chemical Industries, Ltd. Ascorbic acid ethers and their production
JP2515556B2 (ja) * 1986-08-29 1996-07-10 武田薬品工業株式会社 ヒドロキシブテノライド誘導体およびその製造法
KR970005488B1 (ko) * 1988-10-20 1997-04-16 시오노 기세이야꾸 가부시끼가이샤 항생제 pb-6042류
JPH04211676A (ja) * 1990-05-23 1992-08-03 Kao Corp 新規化合物並びにそれを含有する血管拡張剤及び皮膚外用剤
JP3156006B2 (ja) * 1990-07-30 2001-04-16 武田薬品工業株式会社 テトロン酸誘導体、その製造法及び用途
EP0480624A1 (en) * 1990-10-11 1992-04-15 Merck & Co. Inc. Inhibitors of HIV protease
AU2267992A (en) * 1991-08-27 1993-03-16 Upjohn Company, The Compounds used for the inhibition of hiv-protease
DE69226487T2 (de) * 1991-09-26 1999-02-18 Nippon Zoki Pharmaceutical Co., Ltd., Osaka Verwendung von Furanonderivaten zur Vorbeugung oder Behandlung von Autoimmunkrankheiten
ZA938019B (en) * 1992-11-13 1995-04-28 Upjohn Co Pyran-2-ones and 5,6-dihydropyran-2-ones useful for treating HIV and other retroviruses

Also Published As

Publication number Publication date
AU7636894A (en) 1995-04-03
JPH09502713A (ja) 1997-03-18
EP0720607A1 (en) 1996-07-10
TW354294B (en) 1999-03-11
WO1995007901A1 (en) 1995-03-23
US5977169A (en) 1999-11-02
CA2168757A1 (en) 1995-03-23

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