IL109582A - N-(tetrahydropyran-4-yloxy alkanoyl) staurosporin derivatives, process for the preparation thereof and pharmaceutical compositions containing them - Google Patents
N-(tetrahydropyran-4-yloxy alkanoyl) staurosporin derivatives, process for the preparation thereof and pharmaceutical compositions containing themInfo
- Publication number
- IL109582A IL109582A IL109582A IL10958294A IL109582A IL 109582 A IL109582 A IL 109582A IL 109582 A IL109582 A IL 109582A IL 10958294 A IL10958294 A IL 10958294A IL 109582 A IL109582 A IL 109582A
- Authority
- IL
- Israel
- Prior art keywords
- tetrahydropyran
- yloxy
- alkanoyl
- preparation
- pharmaceutical compositions
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/22—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains four or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrane Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH140693 | 1993-05-07 | ||
| CH33594 | 1994-02-04 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL109582A0 IL109582A0 (en) | 1994-08-26 |
| IL109582A true IL109582A (en) | 1997-09-30 |
Family
ID=25684254
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL109582A IL109582A (en) | 1993-05-07 | 1994-05-06 | N-(tetrahydropyran-4-yloxy alkanoyl) staurosporin derivatives, process for the preparation thereof and pharmaceutical compositions containing them |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US5382675A (xx) |
| EP (1) | EP0624590A1 (xx) |
| JP (1) | JPH06329678A (xx) |
| CN (1) | CN1097761A (xx) |
| AU (1) | AU680477B2 (xx) |
| CA (1) | CA2122960A1 (xx) |
| CZ (1) | CZ111894A3 (xx) |
| FI (1) | FI942046A (xx) |
| HU (1) | HUT70763A (xx) |
| IL (1) | IL109582A (xx) |
| MA (1) | MA23188A1 (xx) |
| NO (1) | NO941676L (xx) |
| NZ (1) | NZ260459A (xx) |
| PH (1) | PH30300A (xx) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5624949A (en) * | 1993-12-07 | 1997-04-29 | Eli Lilly And Company | Protein kinase C inhibitors |
| US5604219A (en) * | 1994-03-18 | 1997-02-18 | Kyowa Hakko Kogyo Co., Ltd. | Indolocarbazole derivatives that stimulate platelet production |
| ES2219670T3 (es) * | 1994-11-10 | 2004-12-01 | Millennium Pharmaceuticals, Inc. | Utilizacion de compuestos de pirazola para el tratamiento de la glomerulonefritis, cancer, ateroesclerosis o restenosis. |
| GB9610872D0 (en) * | 1996-05-23 | 1996-07-31 | Ciba Geigy Ag | Protein kinase assay as a method for identification of fungicides |
| US6284783B1 (en) | 1999-06-09 | 2001-09-04 | The Uab Research Foundation | Use of bisindolylmaleimide compounds to induce Fas-mediated apoptosis |
| WO2001004125A1 (fr) | 1999-07-13 | 2001-01-18 | Kyowa Hakko Kogyo Co., Ltd. | Derives de staurosporine |
| WO2005014004A1 (en) | 2003-08-08 | 2005-02-17 | Novartis Ag | Combinations comprising staurosporines |
| CN111296417B (zh) * | 2020-04-01 | 2021-04-20 | 广东省农业科学院植物保护研究所 | 一种星·甲维悬浮剂及其制备方法与应用 |
| CN116041371B (zh) * | 2023-01-29 | 2024-04-19 | 杭州科兴生物化工有限公司 | 7-羰基星孢菌素衍生物及其制备方法和应用 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4100178A (en) * | 1976-04-14 | 1978-07-11 | The Upjohn Company | 4,5-Didehydro-6-methoxy-2-arylmethoxymethyl-4α-tetrahydropyranacetic acid alkyl esters |
| US4100177A (en) * | 1976-04-14 | 1978-07-11 | The Upjohn Company | 4,5-Didehydro-6-hydroxy-2-arylmethoxymethyl-4α-tetrahydropyranacetic acid alkyl esters |
| US4359424A (en) * | 1980-07-07 | 1982-11-16 | Zoecon Corporation | Substituted phenoxyethoxytetrahydropyran |
| US4304924A (en) * | 1980-07-07 | 1981-12-08 | Zoecon Corporation | Cyclopropylmethyl benzoates |
| IL86632A0 (en) * | 1987-06-15 | 1988-11-30 | Ciba Geigy Ag | Derivatives substituted at methyl-amino nitrogen |
| US5093330A (en) * | 1987-06-15 | 1992-03-03 | Ciba-Geigy Corporation | Staurosporine derivatives substituted at methylamino nitrogen |
| JP2766360B2 (ja) * | 1988-02-04 | 1998-06-18 | 協和醗酵工業株式会社 | スタウロスポリン誘導体 |
| DE3924538A1 (de) * | 1989-07-25 | 1991-01-31 | Goedecke Ag | Indolocarbazol und dessen verwendung |
| AU7035991A (en) * | 1989-12-14 | 1991-07-18 | Schering Corporation | Indolocarbazoles from saccharothrix aerocolonigenes subsp. copiosa subsp. nov. scc 1951 atcc 53856 |
| GB9216298D0 (en) * | 1991-08-15 | 1992-09-16 | Ici Plc | Piperidine derivatives |
| US5185260A (en) * | 1991-08-29 | 1993-02-09 | The United States Of America As Represented By The United States Department Of Energy | Method for distinguishing normal and transformed cells using G1 kinase inhibitors |
| EP0541486A1 (de) * | 1991-11-07 | 1993-05-12 | Ciba-Geigy Ag | Polycyclische Konjugate |
| ES2136103T3 (es) * | 1992-06-22 | 1999-11-16 | Kyowa Hakko Kogyo Kk | Procedimiento para la preparacion de derivados de estaurosporina. |
-
1994
- 1994-04-25 PH PH48141A patent/PH30300A/en unknown
- 1994-04-28 US US08/234,763 patent/US5382675A/en not_active Expired - Fee Related
- 1994-04-28 EP EP94810239A patent/EP0624590A1/de not_active Withdrawn
- 1994-05-02 AU AU61828/94A patent/AU680477B2/en not_active Ceased
- 1994-05-04 FI FI942046A patent/FI942046A/fi not_active Application Discontinuation
- 1994-05-05 NZ NZ260459A patent/NZ260459A/en unknown
- 1994-05-05 HU HU9401347A patent/HUT70763A/hu unknown
- 1994-05-05 CZ CZ941118A patent/CZ111894A3/cs unknown
- 1994-05-05 CA CA002122960A patent/CA2122960A1/en not_active Abandoned
- 1994-05-06 NO NO941676A patent/NO941676L/no unknown
- 1994-05-06 MA MA23496A patent/MA23188A1/fr unknown
- 1994-05-06 IL IL109582A patent/IL109582A/xx not_active IP Right Cessation
- 1994-05-06 JP JP6094090A patent/JPH06329678A/ja active Pending
- 1994-05-06 CN CN94104913A patent/CN1097761A/zh active Pending
- 1994-09-20 US US08/309,384 patent/US5455241A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| FI942046A (fi) | 1994-11-08 |
| HU9401347D0 (en) | 1994-08-29 |
| HUT70763A (en) | 1995-10-30 |
| JPH06329678A (ja) | 1994-11-29 |
| NO941676D0 (no) | 1994-05-06 |
| NO941676L (no) | 1994-11-08 |
| AU6182894A (en) | 1994-11-10 |
| CA2122960A1 (en) | 1994-11-08 |
| AU680477B2 (en) | 1997-07-31 |
| MA23188A1 (fr) | 1994-12-31 |
| US5382675A (en) | 1995-01-17 |
| IL109582A0 (en) | 1994-08-26 |
| US5455241A (en) | 1995-10-03 |
| CZ111894A3 (en) | 1994-12-15 |
| PH30300A (en) | 1997-01-20 |
| EP0624590A1 (de) | 1994-11-17 |
| CN1097761A (zh) | 1995-01-25 |
| NZ260459A (en) | 1995-12-21 |
| FI942046A0 (fi) | 1994-05-04 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FF | Patent granted | ||
| KB | Patent renewed | ||
| RH | Patent void |