IL109439A0 - 2-Amino-4-heteroaryl-1, 4-dihydropyridines, processes for their preparation and their use in pharmaceutical compositions - Google Patents
2-Amino-4-heteroaryl-1, 4-dihydropyridines, processes for their preparation and their use in pharmaceutical compositionsInfo
- Publication number
- IL109439A0 IL109439A0 IL10943994A IL10943994A IL109439A0 IL 109439 A0 IL109439 A0 IL 109439A0 IL 10943994 A IL10943994 A IL 10943994A IL 10943994 A IL10943994 A IL 10943994A IL 109439 A0 IL109439 A0 IL 109439A0
- Authority
- IL
- Israel
- Prior art keywords
- dihydropyridines
- heteroaryl
- amino
- processes
- preparation
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Heart & Thoracic Surgery (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Hydrogenated Pyridines (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE4313696A DE4313696A1 (de) | 1993-04-27 | 1993-04-27 | 2-Amino-4-heteroaryl-1,4-dihydropyridine, Verfahren zu ihrer Herstellung und ihre Verwendung in Arzneimitteln |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL109439A0 true IL109439A0 (en) | 1994-07-31 |
Family
ID=6486454
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL10943994A IL109439A0 (en) | 1993-04-27 | 1994-04-26 | 2-Amino-4-heteroaryl-1, 4-dihydropyridines, processes for their preparation and their use in pharmaceutical compositions |
Country Status (17)
| Country | Link |
|---|---|
| US (2) | US5434153A (xx) |
| EP (1) | EP0622365A1 (xx) |
| JP (1) | JPH06321943A (xx) |
| CN (1) | CN1100725A (xx) |
| AU (1) | AU671001B2 (xx) |
| CA (1) | CA2121963A1 (xx) |
| CZ (1) | CZ99594A3 (xx) |
| DE (1) | DE4313696A1 (xx) |
| FI (1) | FI941915A (xx) |
| HU (1) | HUT70540A (xx) |
| IL (1) | IL109439A0 (xx) |
| NO (1) | NO941519L (xx) |
| NZ (1) | NZ260385A (xx) |
| PH (1) | PH30808A (xx) |
| RU (2) | RU94014627A (xx) |
| SK (1) | SK47994A3 (xx) |
| ZA (1) | ZA942884B (xx) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2005025507A2 (en) * | 2003-09-10 | 2005-03-24 | Synta Phamaceuticals Corp. | Dihydropyridine compounds for treating or preventing metabolic disorders |
| CA2752603C (en) | 2009-02-18 | 2016-04-05 | Bayer Pharma Aktiengesellschaft | Bi- and tricyclic indazole-substituted 1,4-dihydropyridine derivatives and uses thereof |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3946026A (en) * | 1972-03-06 | 1976-03-23 | Bayer Aktiengesellschaft | 2-Amino-1,4-dihydropyridine derivatives |
| DE2242786A1 (de) * | 1972-08-31 | 1974-03-14 | Bayer Ag | Verfahren zur herstellung von neuen 2-amino-1,4-dihydropyridinen mit einer carbonylfunktion sowie ihre verwendung als arzneimittel |
| US3989708A (en) * | 1972-08-31 | 1976-11-02 | Bayer Aktiengesellschaft | 2-Amino-1,4-dihydropyridine derivatives |
| DE2639257A1 (de) * | 1976-09-01 | 1978-03-02 | Bayer Ag | Aminoalkylidenamino-1,4-dihydropyridine, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel |
| DE3311003A1 (de) * | 1983-03-25 | 1984-09-27 | Bayer Ag, 5090 Leverkusen | Chromon- und thiochromonsubstituierte 1,4-dihydropyridinlactone, mehrere verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln |
| DE4011106A1 (de) * | 1990-04-06 | 1991-10-10 | Bayer Ag | Neue heterocyclisch substituierte dihydropyridine, verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln |
| US5254692A (en) * | 1990-04-06 | 1993-10-19 | Bayer Aktiengesellschaft | 2,6-dialkyl-4-(benzothiazol- or benzoxazol-7-yl)-1,4-dihydropyridines |
| DE4117750A1 (de) * | 1991-05-30 | 1992-12-24 | Bayer Ag | Neue 2-amino-5-cyano-1,4-dihydropyridine, verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln |
| DE4134760A1 (de) * | 1991-10-22 | 1993-07-08 | Bayer Ag | Aryl-chinolyl-substituierte 1,4-dihydropyridin-dicarbonsaeurederivate, verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln |
| DE4202526A1 (de) * | 1992-01-30 | 1993-08-05 | Bayer Ag | Neue 4-cinnolinyl- und 4-naphthyridinyl-dihydropyridine, verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln |
-
1993
- 1993-04-27 DE DE4313696A patent/DE4313696A1/de not_active Withdrawn
-
1994
- 1994-03-31 AU AU59222/94A patent/AU671001B2/en not_active Ceased
- 1994-04-14 EP EP94105777A patent/EP0622365A1/de not_active Withdrawn
- 1994-04-20 US US08/230,468 patent/US5434153A/en not_active Expired - Fee Related
- 1994-04-22 CA CA002121963A patent/CA2121963A1/en not_active Abandoned
- 1994-04-22 NZ NZ260385A patent/NZ260385A/en unknown
- 1994-04-25 PH PH48148A patent/PH30808A/en unknown
- 1994-04-25 FI FI941915A patent/FI941915A/fi unknown
- 1994-04-26 ZA ZA942884A patent/ZA942884B/xx unknown
- 1994-04-26 JP JP6109205A patent/JPH06321943A/ja active Pending
- 1994-04-26 NO NO941519A patent/NO941519L/no unknown
- 1994-04-26 HU HU9401191A patent/HUT70540A/hu unknown
- 1994-04-26 RU RU94014627/04A patent/RU94014627A/ru unknown
- 1994-04-26 CZ CZ94995A patent/CZ99594A3/cs unknown
- 1994-04-26 SK SK479-94A patent/SK47994A3/sk unknown
- 1994-04-26 RU RU94014255/04A patent/RU94014255A/ru unknown
- 1994-04-26 IL IL10943994A patent/IL109439A0/xx unknown
- 1994-04-27 CN CN94104685A patent/CN1100725A/zh active Pending
-
1995
- 1995-01-23 US US08/377,063 patent/US5478937A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| ZA942884B (en) | 1995-01-04 |
| FI941915A (fi) | 1994-10-28 |
| US5478937A (en) | 1995-12-26 |
| CA2121963A1 (en) | 1994-10-28 |
| FI941915A0 (fi) | 1994-04-25 |
| PH30808A (en) | 1997-10-17 |
| NO941519L (no) | 1994-10-28 |
| DE4313696A1 (de) | 1994-11-03 |
| NZ260385A (en) | 1996-04-26 |
| RU94014627A (ru) | 1997-02-20 |
| RU94014255A (ru) | 1997-02-20 |
| NO941519D0 (xx) | 1994-04-26 |
| JPH06321943A (ja) | 1994-11-22 |
| HU9401191D0 (en) | 1994-07-28 |
| HUT70540A (en) | 1995-10-30 |
| CN1100725A (zh) | 1995-03-29 |
| EP0622365A1 (de) | 1994-11-02 |
| CZ99594A3 (en) | 1994-11-16 |
| AU5922294A (en) | 1994-11-03 |
| AU671001B2 (en) | 1996-08-08 |
| SK47994A3 (en) | 1994-12-07 |
| US5434153A (en) | 1995-07-18 |
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