IL108969A - Substituted (phenyalkoxy-benzyl) aminopropanamide compounds and pharmaceutical compositions containing them - Google Patents

Substituted (phenyalkoxy-benzyl) aminopropanamide compounds and pharmaceutical compositions containing them

Info

Publication number
IL108969A
IL108969A IL10896994A IL10896994A IL108969A IL 108969 A IL108969 A IL 108969A IL 10896994 A IL10896994 A IL 10896994A IL 10896994 A IL10896994 A IL 10896994A IL 108969 A IL108969 A IL 108969A
Authority
IL
Israel
Prior art keywords
oxybenzyl
aminopropanamide
formula
compounds
compound
Prior art date
Application number
IL10896994A
Other languages
English (en)
Other versions
IL108969A0 (en
Inventor
Varasi Mario
Dostert Philippe
Pevarello Paolo
Bonsignori Alberto
Original Assignee
Pharmacia & Upjohn Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia & Upjohn Spa filed Critical Pharmacia & Upjohn Spa
Publication of IL108969A0 publication Critical patent/IL108969A0/xx
Publication of IL108969A publication Critical patent/IL108969A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/02Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C237/04Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C237/06Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/26Psychostimulants, e.g. nicotine, cocaine

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
IL10896994A 1993-04-01 1994-03-14 Substituted (phenyalkoxy-benzyl) aminopropanamide compounds and pharmaceutical compositions containing them IL108969A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB939306886A GB9306886D0 (en) 1993-04-01 1993-04-01 Substituted (arylakoxybenzyl) aminopropanamide derivatives and process for their preparation

Publications (2)

Publication Number Publication Date
IL108969A0 IL108969A0 (en) 1994-06-24
IL108969A true IL108969A (en) 1998-10-30

Family

ID=10733215

Family Applications (1)

Application Number Title Priority Date Filing Date
IL10896994A IL108969A (en) 1993-04-01 1994-03-14 Substituted (phenyalkoxy-benzyl) aminopropanamide compounds and pharmaceutical compositions containing them

Country Status (19)

Country Link
US (1) US5446066A (de)
EP (1) EP0643688B1 (de)
JP (1) JP3542599B2 (de)
KR (1) KR950701904A (de)
CN (1) CN1035938C (de)
AT (1) ATE168991T1 (de)
AU (1) AU667164B2 (de)
CA (1) CA2135783C (de)
DE (1) DE69412016T2 (de)
ES (1) ES2122253T3 (de)
FI (1) FI945581A0 (de)
GB (1) GB9306886D0 (de)
HU (1) HUT68256A (de)
IL (1) IL108969A (de)
NZ (1) NZ262907A (de)
PL (1) PL306537A1 (de)
RU (1) RU94046141A (de)
WO (1) WO1994022808A1 (de)
ZA (1) ZA941963B (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9515412D0 (en) * 1995-07-27 1995-09-27 Pharmacia Spa 2-(4-substituted)-benzylamino-2-methyl-propanamide derivatives
IT1283489B1 (it) * 1996-07-23 1998-04-21 Chiesi Farma Spa Ammidi di alfa-amminoacidi,loro preparazione e loro impiego terapeutico
FR2753967B1 (fr) * 1996-09-27 1998-11-27 Sod Conseils Rech Applic Nouveaux derives de la phenoxyethylamine, leur procede de preparation, leur application comme medicaments et les compositions pharmaceutiques les renfermant
GB9706730D0 (en) * 1997-04-03 1997-05-21 Pharmacia & Upjohn Spa 2-[(3-substituted)-5-Isoxazolymethylaminojalkanamid derivatives
EP1032377B1 (de) 1997-11-21 2010-11-17 Purdue Neuroscience Company Substituierte 2-aminoacetamide und anwendung davon
GB9727523D0 (en) 1997-12-31 1998-02-25 Pharmacia & Upjohn Spa Alpha-aminoamide derivatives useful as analgesic agents
US6281211B1 (en) 1999-02-04 2001-08-28 Euro-Celtique S.A. Substituted semicarbazides and the use thereof
DK1169060T3 (da) * 1999-04-09 2006-01-16 Euro Celtique Sa Natriumkanalblokkerpræparater og anvendelse deraf
DK1423168T3 (da) 2001-09-03 2006-05-15 Newron Pharm Spa Farmaceutisk præparat omfattende gabapentin eller en analog deraf og et alfa-aminoamid og dets analgetiske anvendelse
US6667327B2 (en) 2002-02-04 2003-12-23 Hoffmann-La Roche Inc. Pyridine amido derivatives
EP1438956A1 (de) 2003-01-16 2004-07-21 Newron Pharmaceuticals S.p.A. Alpha-Aminoamidderivate die als Antimigränemittel nützlich sind
AR044007A1 (es) 2003-04-11 2005-08-24 Newron Pharmaceuticals Inc Metodos para el tratamiento de la enfermedad de parkinson
EP1524265A1 (de) * 2003-10-15 2005-04-20 Newron Pharmaceuticals S.p.A. Prolinamide-Derivate als Natrium- und/oder Kalziumkanalblocker oder selektive MAO-B Inhibitoren
AU2004283452A1 (en) * 2003-10-23 2005-05-06 F. Hoffmann-La Roche Ag Benzazepine derivatives as MAO-B inhibitors
EP1588704A1 (de) 2004-04-22 2005-10-26 Newron Pharmaceuticals S.p.A. Alpha-aminoamidderivate zur Behandlung des Restless-Leg-Syndroms und der Suchterkrankungen
DK1809271T5 (da) * 2004-09-10 2010-12-06 Newron Pharm Spa Anvendelse af (R)-(halogenbenzyloxy)benzylaminopropanamider som natrium- og/eller calciumkanalselektive modulatorer
EP1870097A1 (de) * 2006-06-15 2007-12-26 Newron Pharmaceuticals S.p.A. Alpha-aminoamidederivate zur Behandlung von kognitiven Störungen

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1140748A (en) * 1966-06-23 1969-01-22 Ici Ltd New carboxylic acid derivatives
US4049663A (en) * 1972-06-06 1977-09-20 Allen & Hanburys Limited Ethylene diamine derivatives
DE3010599A1 (de) * 1979-03-22 1980-10-09 Continental Pharma Derivate von glycinamid, deren herstellung und verwendung
FR2480747A1 (fr) * 1980-04-17 1981-10-23 Roques Bernard Derives d'acides amines et leur application therapeutique
US4839369A (en) * 1985-04-16 1989-06-13 Rorer Pharmaceutical Corporation Aryl and heteroaryl ethers as agents for the treatment of hypersensitive ailments
US4728668A (en) * 1985-04-16 1988-03-01 Usv Pharmaceutical Corporation Aryl and heteroaryl ethers as agents for the treatment of hypersensitive ailments
US4631287A (en) * 1985-04-16 1986-12-23 Usv Pharmaceutical Corp. Aryl and heteroaryl ethers as agents for the treatment of hypersensitive ailments
US4725619A (en) * 1985-04-16 1988-02-16 Usv Pharmaceutical Corporation Aryl and heteroaryl ethers as agents for the treatment of hypersensitive ailments
IL94466A (en) * 1989-05-25 1995-01-24 Erba Carlo Spa Pharmaceutical preparations containing the history of A-amino carboxamide N-phenylalkyl are converted into such new compounds and their preparation

Also Published As

Publication number Publication date
FI945581A7 (fi) 1994-11-28
EP0643688B1 (de) 1998-07-29
FI945581L (fi) 1994-11-28
CN1104017A (zh) 1995-06-21
EP0643688A1 (de) 1995-03-22
CA2135783A1 (en) 1994-10-13
JPH07507814A (ja) 1995-08-31
PL306537A1 (en) 1995-04-03
FI945581A0 (fi) 1994-11-28
ZA941963B (en) 1994-10-19
RU94046141A (ru) 1996-09-27
DE69412016T2 (de) 1999-02-11
WO1994022808A1 (en) 1994-10-13
ATE168991T1 (de) 1998-08-15
HUT68256A (en) 1995-06-28
ES2122253T3 (es) 1998-12-16
KR950701904A (ko) 1995-05-17
GB9306886D0 (en) 1993-05-26
AU6284294A (en) 1994-10-24
DE69412016D1 (de) 1998-09-03
CN1035938C (zh) 1997-09-24
NZ262907A (en) 1996-02-27
CA2135783C (en) 2005-06-07
IL108969A0 (en) 1994-06-24
JP3542599B2 (ja) 2004-07-14
US5446066A (en) 1995-08-29
AU667164B2 (en) 1996-03-07

Similar Documents

Publication Publication Date Title
US5391577A (en) N-phenylalkyl substituted α-amino carboxamide derivatives and process for their preparation
US5446066A (en) Substituted (arylalkoxybenzyl)aminopropanamide derivatives and process for their preparation
AU711309C (en) 2-(4-substituted)-benzylamino-2-methyl-propanamide derivatives
EA002763B1 (ru) Альфа-аминоамидные производные, полезные в качестве анальгетических агентов
US5912242A (en) N-(4-substituted-benzyl)-2-aminolactam derivatives
US6303819B1 (en) Substituted 2-benzylamino-2-phenyl-acetamide compounds
US5449692A (en) Substituted (arylalkylaminobenzyl) aminopropionamide derivatives and process for their preparation
KR20010033998A (ko) 신경학적 질병 치료용 1,4-디아자시클로헵탄 유도체
HK1028021B (en) Substituted 2-benzylamino-2-phenyl-acetamide compounds

Legal Events

Date Code Title Description
FF Patent granted
RH Patent void