IL108486A - 9H-INDENO £1, 2-b|-2(1H)-ONE DERIVATIVES AND ANALOGS, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM - Google Patents

9H-INDENO £1, 2-b|-2(1H)-ONE DERIVATIVES AND ANALOGS, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

Info

Publication number
IL108486A
IL108486A IL108486A IL10848694A IL108486A IL 108486 A IL108486 A IL 108486A IL 108486 A IL108486 A IL 108486A IL 10848694 A IL10848694 A IL 10848694A IL 108486 A IL108486 A IL 108486A
Authority
IL
Israel
Prior art keywords
formula
compound
pyrazine
indeno
dione
Prior art date
Application number
IL108486A
Other languages
English (en)
Other versions
IL108486A0 (en
Original Assignee
Novo Nordisk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk As filed Critical Novo Nordisk As
Publication of IL108486A0 publication Critical patent/IL108486A0/xx
Publication of IL108486A publication Critical patent/IL108486A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D241/00Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/36Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems
    • C07D241/38Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems with only hydrogen or carbon atoms directly attached to the ring nitrogen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/26Psychostimulants, e.g. nicotine, cocaine
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/645Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having two nitrogen atoms as the only ring hetero atoms
    • C07F9/6509Six-membered rings
    • C07F9/650952Six-membered rings having the nitrogen atoms in the positions 1 and 4
    • C07F9/650994Six-membered rings having the nitrogen atoms in the positions 1 and 4 condensed with carbocyclic rings or carbocyclic ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Liquid Crystal Substances (AREA)
  • Photoreceptors In Electrophotography (AREA)
  • Polyesters Or Polycarbonates (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
IL108486A 1993-02-02 1994-01-31 9H-INDENO £1, 2-b|-2(1H)-ONE DERIVATIVES AND ANALOGS, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM IL108486A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DK93122A DK12293D0 (da) 1993-02-02 1993-02-02 Heterocykliske forbindelser og deres fremstilling og anvendelse

Publications (2)

Publication Number Publication Date
IL108486A0 IL108486A0 (en) 1994-05-30
IL108486A true IL108486A (en) 1998-01-04

Family

ID=8090000

Family Applications (1)

Application Number Title Priority Date Filing Date
IL108486A IL108486A (en) 1993-02-02 1994-01-31 9H-INDENO £1, 2-b|-2(1H)-ONE DERIVATIVES AND ANALOGS, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

Country Status (14)

Country Link
US (2) US5468748A (de)
EP (1) EP0682657B1 (de)
JP (1) JPH08508979A (de)
AT (1) ATE160342T1 (de)
AU (1) AU674205B2 (de)
CA (1) CA2155355A1 (de)
DE (1) DE69406907D1 (de)
DK (1) DK12293D0 (de)
FI (1) FI953666L (de)
IL (1) IL108486A (de)
NO (1) NO953034L (de)
NZ (1) NZ261299A (de)
WO (1) WO1994018175A1 (de)
ZA (1) ZA94711B (de)

Families Citing this family (52)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2717813B1 (fr) * 1994-03-28 1996-05-10 Rhone Poulenc Rorer Sa Dérivés d'imidazo[1,2-a]indeno[1,2-e]pyrazine-4-one, leur préparation et les médicaments les contenant .
FR2717812B1 (fr) * 1994-03-28 1996-05-10 Rhone Poulenc Rorer Sa Indeno[1,2-e]pyrazine-4-ones, leur préparation et les médicaments les contenant.
FR2717805B1 (fr) * 1994-03-28 1996-05-10 Rhone Poulenc Rorer Sa Dérivés de 5H-indeno[1,2-b]pyrazine-2,3-dione, leur préparation et les médicaments les contenant .
FR2743363A1 (fr) * 1996-01-10 1997-07-11 Rhone Poulenc Rorer Sa 5h,10h-imidazo(1,2-a)indeno(1,2-e)pyrazine-a-ones substituees en position 2, leur preparation et les medicaments les contenant
US7637948B2 (en) 1997-10-10 2009-12-29 Senorx, Inc. Tissue marking implant
US8668737B2 (en) 1997-10-10 2014-03-11 Senorx, Inc. Tissue marking implant
US6270464B1 (en) * 1998-06-22 2001-08-07 Artemis Medical, Inc. Biopsy localization method and device
US6875182B2 (en) 1998-03-03 2005-04-05 Senorx, Inc. Electrosurgical specimen-collection system
US6497706B1 (en) 1998-03-03 2002-12-24 Senorx, Inc. Biopsy device and method of use
US6758848B2 (en) * 1998-03-03 2004-07-06 Senorx, Inc. Apparatus and method for accessing a body site
US6638234B2 (en) 1998-03-03 2003-10-28 Senorx, Inc. Sentinel node location and biopsy
US6161034A (en) * 1999-02-02 2000-12-12 Senorx, Inc. Methods and chemical preparations for time-limited marking of biopsy sites
US6347241B2 (en) * 1999-02-02 2002-02-12 Senorx, Inc. Ultrasonic and x-ray detectable biopsy site marker and apparatus for applying it
US6540695B1 (en) 1998-04-08 2003-04-01 Senorx, Inc. Biopsy anchor device with cutter
US20020058882A1 (en) * 1998-06-22 2002-05-16 Artemis Medical, Incorporated Biopsy localization method and device
US6679851B2 (en) 1998-09-01 2004-01-20 Senorx, Inc. Tissue accessing and anchoring device and method
US7651505B2 (en) 2002-06-17 2010-01-26 Senorx, Inc. Plugged tip delivery for marker placement
US9820824B2 (en) 1999-02-02 2017-11-21 Senorx, Inc. Deployment of polysaccharide markers for treating a site within a patent
US6862470B2 (en) 1999-02-02 2005-03-01 Senorx, Inc. Cavity-filling biopsy site markers
US20090216118A1 (en) * 2007-07-26 2009-08-27 Senorx, Inc. Polysaccharide markers
US7983734B2 (en) 2003-05-23 2011-07-19 Senorx, Inc. Fibrous marker and intracorporeal delivery thereof
US6725083B1 (en) * 1999-02-02 2004-04-20 Senorx, Inc. Tissue site markers for in VIVO imaging
US8498693B2 (en) 1999-02-02 2013-07-30 Senorx, Inc. Intracorporeal marker and marker delivery device
US20080039819A1 (en) * 2006-08-04 2008-02-14 Senorx, Inc. Marker formed of starch or other suitable polysaccharide
US8361082B2 (en) 1999-02-02 2013-01-29 Senorx, Inc. Marker delivery device with releasable plug
US6575991B1 (en) 1999-06-17 2003-06-10 Inrad, Inc. Apparatus for the percutaneous marking of a lesion
AU2002239290A1 (en) 2000-11-20 2002-06-03 Senorx, Inc. Tissue site markers for in vivo imaging
US20060036158A1 (en) 2003-11-17 2006-02-16 Inrad, Inc. Self-contained, self-piercing, side-expelling marking apparatus
US7125586B2 (en) * 2003-04-11 2006-10-24 Delphi Technologies, Inc. Kinetic spray application of coatings onto covered materials
US20050119562A1 (en) * 2003-05-23 2005-06-02 Senorx, Inc. Fibrous marker formed of synthetic polymer strands
US7877133B2 (en) 2003-05-23 2011-01-25 Senorx, Inc. Marker or filler forming fluid
US20050273002A1 (en) 2004-06-04 2005-12-08 Goosen Ryan L Multi-mode imaging marker
US9408592B2 (en) 2003-12-23 2016-08-09 Senorx, Inc. Biopsy device with aperture orientation and improved tip
US8343071B2 (en) 2004-12-16 2013-01-01 Senorx, Inc. Biopsy device with aperture orientation and improved tip
EP4123261B1 (de) * 2005-03-18 2024-04-03 Gatekeeper Systems, Inc. Zweiwege-kommunikationssystem zur verfolgung von standort und status eines radfahrzeuges
US10357328B2 (en) 2005-04-20 2019-07-23 Bard Peripheral Vascular, Inc. and Bard Shannon Limited Marking device with retractable cannula
US9095325B2 (en) 2005-05-23 2015-08-04 Senorx, Inc. Tissue cutting member for a biopsy device
US7572236B2 (en) 2005-08-05 2009-08-11 Senorx, Inc. Biopsy device with fluid delivery to tissue specimens
US8317725B2 (en) 2005-08-05 2012-11-27 Senorx, Inc. Biopsy device with fluid delivery to tissue specimens
CA2562580C (en) 2005-10-07 2014-04-29 Inrad, Inc. Drug-eluting tissue marker
US20080230001A1 (en) * 2006-02-23 2008-09-25 Meadwestvaco Corporation Method for treating a substrate
WO2008051749A2 (en) 2006-10-23 2008-05-02 C. R. Bard, Inc. Breast marker
EP3542748B1 (de) 2006-12-12 2023-08-16 C. R. Bard, Inc. Gewebemarker mit mehreren bildgebungsmodi
ES2432572T3 (es) 2006-12-18 2013-12-04 C.R. Bard, Inc. Marcador de biopsia con propiedades de obtención de imágenes generadas in situ
SI2221296T1 (sl) * 2007-11-28 2012-10-30 Astellas Pharma Inc Kondenzirana indanska spojina
US8311610B2 (en) 2008-01-31 2012-11-13 C. R. Bard, Inc. Biopsy tissue marker
US9327061B2 (en) 2008-09-23 2016-05-03 Senorx, Inc. Porous bioabsorbable implant
CA2742765C (en) 2008-12-30 2016-04-12 C.R. Bard Inc. Marker delivery device for tissue marker placement
USD716451S1 (en) 2013-09-24 2014-10-28 C. R. Bard, Inc. Tissue marker for intracorporeal site identification
USD715942S1 (en) 2013-09-24 2014-10-21 C. R. Bard, Inc. Tissue marker for intracorporeal site identification
USD715442S1 (en) 2013-09-24 2014-10-14 C. R. Bard, Inc. Tissue marker for intracorporeal site identification
USD716450S1 (en) 2013-09-24 2014-10-28 C. R. Bard, Inc. Tissue marker for intracorporeal site identification

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK146787A (da) * 1987-03-23 1988-09-24 Ferrosan Heterocykliske forbindelser, deres fremstilling og anvendelse
NO179551C (no) * 1987-11-10 1996-10-30 Novo Nordisk As Analogifremgangsmåte for fremstilling av terapeutisk virksomme kinoxalinforbindelser
DK716188D0 (da) * 1988-12-22 1988-12-22 Ferrosan As Quinoxalinforbindelser, deres fremstilling og anvendelse
US5153195A (en) * 1988-12-22 1992-10-06 Novo Nordisk A/S Quinoxaline compounds and their preparation and use
DK101290D0 (da) * 1990-04-24 1990-04-24 Novo Nordisk As Heterocykliske forbindelser, deres fremstilling og anvendelse
DK73091D0 (da) * 1991-04-22 1991-04-22 Novo Nordisk As Quinoxalinforbindelser, deres fremstilling og anvendelse
FR2717805B1 (fr) * 1994-03-28 1996-05-10 Rhone Poulenc Rorer Sa Dérivés de 5H-indeno[1,2-b]pyrazine-2,3-dione, leur préparation et les médicaments les contenant .

Also Published As

Publication number Publication date
IL108486A0 (en) 1994-05-30
AU5998694A (en) 1994-08-29
CA2155355A1 (en) 1994-08-18
NO953034L (no) 1995-09-29
EP0682657B1 (de) 1997-11-19
AU674205B2 (en) 1996-12-12
NZ261299A (en) 1997-02-24
US5468748A (en) 1995-11-21
FI953666A7 (fi) 1995-09-28
DK12293D0 (da) 1993-02-02
ZA94711B (en) 1995-08-02
FI953666L (fi) 1995-09-28
FI953666A0 (fi) 1995-08-01
US5646146A (en) 1997-07-08
JPH08508979A (ja) 1996-09-24
ATE160342T1 (de) 1997-12-15
EP0682657A1 (de) 1995-11-22
DE69406907D1 (de) 1998-01-02
NO953034D0 (no) 1995-08-01
WO1994018175A1 (en) 1994-08-18

Similar Documents

Publication Publication Date Title
AU674205B2 (en) Heterocyclic Compounds and Their Preparation and Use
EP0315959B1 (de) Chinoxalinverbindungen und deren Herstellung und Verwendung
CZ2002616A3 (cs) Isomerní kondenzované pyrrolokarbazoly a isoindolony
US5922716A (en) 5H-indeno 1,2-b!pyrazine-2,3-dione derivatives, their preparation and medicinal products containing them
EP1490361B1 (de) Polycyclische verbindungen als potenten alpha2-adrenoceptor antagonisten
IL92464A (en) Quinoxaline compounds their preparation and pharmaceutical compositions containing them
EP0377112B1 (de) Chinoxalin-Verbindungen, ihre Herstellung und Verwendung
AU652560B2 (en) Quinoxaline compounds and their preparation and use
JP2015172098A (ja) 複素二環スピロ化合物又はその薬学的に許容される塩、これらの化合物を含む医薬組成物、および哺乳類のアルツハイマー病及びインスリン抵抗性症候群及び2型糖尿病を治療するための薬剤の調整における、これらの化合物の利用
US5753657A (en) Imidazo 1,2-A! pyrazine-4-one, preparation thereof and drugs containing same
FI106719B (fi) Menetelmä terapeuttisesti käyttökelpoisten [1,2,4]triatsolo[4,3-a]kinoksaliini-1,4-dionien ja -4-onien valmistamiseksi
US5777114A (en) Spiro heterocycle-imidazo 1,2-a!indeno 1,2-e!pyrazine!-4'-ones, preparation thereof and drugs containing same
AU685783B2 (en) (1,2,4) triazolo (4,3-a) quinoxaline derivatives, their preparation and use
CA2157231A1 (en) Oxa- or thia-aliphatically bridged quinoxaline-2,3-diones
US5182279A (en) Benzothienopyrazinedione compounds and their preparation and use
PT752992E (pt) Derivados de imidazo¬1,2-a|indeno¬1,2-e|pirazin-4-ona e composicoes farmaceuticas que os contem
EP0511152A2 (de) Quinoxalin-Verbindungen, ihre Herstellung und Verwendung
US5308845A (en) Quinoxaline compounds and their preparation and use
US5284847A (en) Thieno pyrazine diones, their preparation and use
WO1996008492A1 (en) [1,2,4]TRIAZOLO[4,3-a]QUINOXALINONE DERIVATIVES, THEIR PREPARATION AND USE
US5491163A (en) (Thia)cycloalkyl[B]indoles
AU1401600A (en) Novel type condensed pyridazinone compounds

Legal Events

Date Code Title Description
FF Patent granted