IL105958A - Somatotropin complexes with aromatic aldehydes and sustained-release pharmaceutical compositions containing them - Google Patents

Somatotropin complexes with aromatic aldehydes and sustained-release pharmaceutical compositions containing them

Info

Publication number
IL105958A
IL105958A IL105958A IL10595893A IL105958A IL 105958 A IL105958 A IL 105958A IL 105958 A IL105958 A IL 105958A IL 10595893 A IL10595893 A IL 10595893A IL 105958 A IL105958 A IL 105958A
Authority
IL
Israel
Prior art keywords
somatotropin
sustained
complexes
pharmaceutical compositions
compositions containing
Prior art date
Application number
IL105958A
Other languages
English (en)
Other versions
IL105958A0 (en
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of IL105958A0 publication Critical patent/IL105958A0/xx
Publication of IL105958A publication Critical patent/IL105958A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/61Growth hormone [GH], i.e. somatotropin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/54Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Endocrinology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Toxicology (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Reproductive Health (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Fodder In General (AREA)
  • Feed For Specific Animals (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Cultivation Of Plants (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
IL105958A 1992-06-11 1993-06-08 Somatotropin complexes with aromatic aldehydes and sustained-release pharmaceutical compositions containing them IL105958A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/896,958 US5198422A (en) 1992-06-11 1992-06-11 Stabilized somatotropin for parenteral administration

Publications (2)

Publication Number Publication Date
IL105958A0 IL105958A0 (en) 1993-10-20
IL105958A true IL105958A (en) 1997-11-20

Family

ID=25407118

Family Applications (1)

Application Number Title Priority Date Filing Date
IL105958A IL105958A (en) 1992-06-11 1993-06-08 Somatotropin complexes with aromatic aldehydes and sustained-release pharmaceutical compositions containing them

Country Status (20)

Country Link
US (1) US5198422A (zh)
EP (1) EP0644770B1 (zh)
JP (1) JP3247380B2 (zh)
KR (1) KR100269896B1 (zh)
CN (1) CN1069214C (zh)
AT (1) ATE175355T1 (zh)
AU (1) AU670805B2 (zh)
CA (1) CA2137677C (zh)
DE (1) DE69322958T2 (zh)
DK (1) DK0644770T3 (zh)
ES (1) ES2125990T3 (zh)
GR (1) GR3029291T3 (zh)
HU (1) HU223944B1 (zh)
IL (1) IL105958A (zh)
NO (1) NO314784B1 (zh)
NZ (1) NZ253914A (zh)
PL (1) PL175971B1 (zh)
TW (1) TW341513B (zh)
WO (1) WO1993025222A1 (zh)
ZA (1) ZA934100B (zh)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA949350B (en) 1994-01-25 1996-05-24 Upjohn Co Aqueous prolonged release formulation
KR19990071255A (ko) 1998-02-28 1999-09-15 성재갑 소마토트로핀과 비타민의 합제 조성물
IL139585A0 (en) * 1998-06-26 2002-02-10 Pfizer Prod Inc Improved process for preparing schiff base adducts of amines with 0-hydroxy aldehydes and compositions of matter based thereon
US20080113025A1 (en) * 1998-11-02 2008-05-15 Elan Pharma International Limited Compositions comprising nanoparticulate naproxen and controlled release hydrocodone
JP2001316294A (ja) * 2000-03-14 2001-11-13 Pfizer Prod Inc o−バニリンおよびo−バニリン/テトラメチルクロマニルカルボン酸化合物の組み合わせの使用法
CN100369953C (zh) * 2002-09-09 2008-02-20 尼克塔治疗亚拉巴马公司 水溶性聚合物链烷醛
SG176314A1 (en) 2002-12-31 2011-12-29 Altus Pharmaceuticals Inc Human growth hormone crystals and methods for preparing them
CA2512001A1 (en) * 2002-12-31 2004-07-22 Altus Pharmaceuticals Inc. Complexes of protein crystals and ionic polymers
TWI429436B (zh) * 2007-04-10 2014-03-11 Helsinn Therapeutics Us Inc 使用生長激素促泌素治療或預防嘔吐之方法
CN102015606B (zh) 2007-06-08 2015-02-04 满康德股份有限公司 IRE-1α抑制剂
ITMI20130341A1 (it) 2013-03-07 2014-09-08 Gm Morando S R L Sistema schermante modulare
CN108883066A (zh) * 2016-01-29 2018-11-23 日产化学株式会社 控制了水溶性有效成分的释放的经皮吸收组合物

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1296253C (en) * 1986-10-20 1992-02-25 Praveen Tyle Stabilized growth hormone compositions
EP0374120A3 (en) * 1988-12-13 1991-07-31 Monsanto Company Comosition for controlled release of polypeptides
US5015627A (en) * 1990-07-20 1991-05-14 Smithkline Beecham Corporation Stabilized somatotropin for parenteral administration

Also Published As

Publication number Publication date
NO314784B1 (no) 2003-05-26
DE69322958T2 (de) 1999-05-27
ZA934100B (en) 1994-06-10
JP3247380B2 (ja) 2002-01-15
JPH07508003A (ja) 1995-09-07
AU670805B2 (en) 1996-08-01
IL105958A0 (en) 1993-10-20
HUT68917A (en) 1995-08-28
DE69322958D1 (de) 1999-02-18
DK0644770T3 (da) 1999-08-30
EP0644770B1 (en) 1999-01-07
EP0644770A4 (en) 1995-10-25
WO1993025222A1 (en) 1993-12-23
NZ253914A (en) 1997-12-19
CN1085804A (zh) 1994-04-27
NO944782D0 (no) 1994-12-09
HU9403548D0 (en) 1995-02-28
EP0644770A1 (en) 1995-03-29
ES2125990T3 (es) 1999-03-16
ATE175355T1 (de) 1999-01-15
NO944782L (no) 1994-12-09
CN1069214C (zh) 2001-08-08
GR3029291T3 (en) 1999-05-28
KR100269896B1 (ko) 2000-10-16
PL175971B1 (pl) 1999-03-31
HU223944B1 (hu) 2005-03-29
CA2137677C (en) 1998-08-25
US5198422A (en) 1993-03-30
AU4535493A (en) 1994-01-04
CA2137677A1 (en) 1993-12-23
TW341513B (en) 1998-10-01

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Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
KB Patent renewed
KB Patent renewed
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees