IL104112A - 6-deoxy hexofuranose monosaccharide derivatives and pharmaceutical compositions containing them - Google Patents
6-deoxy hexofuranose monosaccharide derivatives and pharmaceutical compositions containing themInfo
- Publication number
- IL104112A IL104112A IL104112A IL10411292A IL104112A IL 104112 A IL104112 A IL 104112A IL 104112 A IL104112 A IL 104112A IL 10411292 A IL10411292 A IL 10411292A IL 104112 A IL104112 A IL 104112A
- Authority
- IL
- Israel
- Prior art keywords
- pharmaceutical compositions
- deoxy
- compounds
- compositions containing
- hexofuranose
- Prior art date
Links
- -1 hexofuranose monosaccharide derivatives Chemical class 0.000 title abstract 3
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 4
- 208000023275 Autoimmune disease Diseases 0.000 abstract 1
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 1
- 230000001028 anti-proliverative effect Effects 0.000 abstract 1
- 208000027866 inflammatory disease Diseases 0.000 abstract 1
- 230000002757 inflammatory effect Effects 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/02—Acyclic radicals, not substituted by cyclic structures
- C07H15/12—Acyclic radicals, not substituted by cyclic structures attached to a nitrogen atom of the saccharide radical
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/24—Heterocyclic radicals containing oxygen or sulfur as ring hetero atom
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Crystallography & Structural Chemistry (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Compounds Of Unknown Constitution (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US81090691A | 1991-12-20 | 1991-12-20 | |
| US07/905,320 US5360792A (en) | 1991-12-20 | 1992-06-29 | Anti-proliferative and anti-inflammatory compounds: 5- or 6-deoxy hexose monosaccharides having a saturated nitrogen-containing heterocycle at the 5- or 6-position bound through the nitrogen atom |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL104112A0 IL104112A0 (en) | 1993-05-13 |
| IL104112A true IL104112A (en) | 1997-09-30 |
Family
ID=27123396
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL104112A IL104112A (en) | 1991-12-20 | 1992-12-16 | 6-deoxy hexofuranose monosaccharide derivatives and pharmaceutical compositions containing them |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US5360792A (OSRAM) |
| EP (1) | EP0581916B1 (OSRAM) |
| JP (1) | JPH06508152A (OSRAM) |
| CN (1) | CN1077198A (OSRAM) |
| AT (1) | ATE163422T1 (OSRAM) |
| CA (1) | CA2104477A1 (OSRAM) |
| DE (1) | DE69224520T2 (OSRAM) |
| FI (1) | FI106863B (OSRAM) |
| IL (1) | IL104112A (OSRAM) |
| NZ (1) | NZ246305A (OSRAM) |
| TW (1) | TW293013B (OSRAM) |
| WO (1) | WO1993013117A2 (OSRAM) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5432163A (en) * | 1992-11-13 | 1995-07-11 | Greenwich Pharmaceuticals Incorporated | Anti-proliferative and anti-inflammatory compounds: derivatives of pentose monosaccharides |
| JPH09501148A (ja) * | 1993-06-11 | 1997-02-04 | ボストン ライフ サイエンシィズ，インコーポレイテッド | 免疫調節性、抗炎症性および抗増殖性化合物：イドースの５，６−ジデオキシ，５−アミノ誘導体およびグルコースの６−デオキシ，６−アミノ誘導体 |
| US6329344B1 (en) | 1998-10-22 | 2001-12-11 | Ranbaxy Laboratories Limited | Derivatives of monosaccharides as cell adhesion inhibitors |
| EP1146906B1 (en) | 1999-02-05 | 2011-07-06 | Alk-Abelló A/S | Mucosal delivery system |
| WO2005092907A2 (en) * | 2004-03-26 | 2005-10-06 | Ranbaxy Laboratories Limited | Monosaccharide derivatives as anti-cancer and anti-inflammatory agents |
| WO2005100373A2 (en) * | 2004-04-13 | 2005-10-27 | Ranbaxy Laboratories Limited | Monosaccharide derivatives as anti-cancer and anti-inflammatory agents |
| WO2006115509A2 (en) * | 2004-06-24 | 2006-11-02 | Novartis Vaccines And Diagnostics Inc. | Small molecule immunopotentiators and assays for their detection |
| US20090221515A1 (en) * | 2004-09-02 | 2009-09-03 | Viswajanani Jitendra Sattigeri | Monosaccharide derivatives |
| JP2008525421A (ja) * | 2004-12-22 | 2008-07-17 | ランバクシー ラボラトリーズ リミテッド | モノサッカリド誘導体 |
| US20080114031A1 (en) * | 2006-03-29 | 2008-05-15 | Sattigeri Viswajanani J | Monosaccharide derivatives |
| EP1864992A2 (en) * | 2006-05-30 | 2007-12-12 | Ranbaxy Laboratories, Ltd. | Monosaccharide derivatives |
| EP1953170A1 (en) * | 2006-10-03 | 2008-08-06 | Ranbaxy Laboratories Limited | Monosaccharide derivatives as anti-inflammatory agents |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2715121A (en) * | 1950-09-09 | 1955-08-09 | American Home Prod | Alkyl sugar derivatives and their preparation |
| US3965262A (en) * | 1973-03-01 | 1976-06-22 | Strategic Medical Research Corporation | Method of enhancing learning and/or memory in warm blooded animals |
| US4016261A (en) * | 1973-03-01 | 1977-04-05 | Strategic Medical Research Corporation | Therapeutic composition and method of therapeutically treating warm blooded animals therewith |
| USRE30379E (en) * | 1973-03-01 | 1980-08-19 | Strategic Medical Research Corp. | Ethereal monosubstitutions of monosaccharide derivatives |
| US3939145A (en) * | 1973-03-01 | 1976-02-17 | Strategic Medical Research Corporation | Novel ethereally monosubstituted monosaccharides |
| USRE32268E (en) * | 1973-03-01 | 1986-10-21 | Strategic Medical Research Corp. | Therapeutic composition and method of therapeutically treating warm blooded animals therewith |
| US3939146A (en) * | 1973-03-01 | 1976-02-17 | Strategic Medical Research Corporation | Novel ethereal monosubstitutions of monosaccharide derivatives |
| US4056322A (en) * | 1973-12-14 | 1977-11-01 | Strategic Medical Research Corporation | Preparation of ethers of monosaccharides |
| US4017608A (en) * | 1973-12-14 | 1977-04-12 | Strategic Medical Research Corporation | Therapeutic composition and method of therapeutically treating warm blooded animals therewith |
| GB1589916A (en) * | 1976-11-16 | 1981-05-20 | Prodotti Antibiotici Spa | Glucofuranose derivatives |
| USRE30354E (en) * | 1978-02-17 | 1980-07-29 | Strategic Medical Research Corp. | Novel ethereally monosubstituted monosaccharides |
| USRE33000E (en) * | 1981-01-12 | 1989-07-25 | Greenwich Pharmaceuticals, Incorporated | Therapeutic composition and method of treating viruses |
| US4738953A (en) * | 1981-02-17 | 1988-04-19 | Greenwich Pharmaceuticals Incorporated | Method of therapeutically treating a warm blooded animal afflicted with an autoimmune disease and a synergistic composition therefor |
| US4735934A (en) * | 1981-02-17 | 1988-04-05 | Greenwich Pharmaceuticals Incorporated | Method of therapeutically treating a warm blooded animal afflicted with an autoimmune disease |
| US4996195A (en) * | 1989-01-09 | 1991-02-26 | Greenwich Pharmaceuticals Inc. | Derivatives of α,D-glucofuranose or α,D-allofuranose and intermediates for preparing these derivatives |
| US5010058A (en) * | 1989-06-22 | 1991-04-23 | 501 Greenwich Pharmaceuticals Incorporated | 3,5,6-substituted derivatives of 1,2-O-isopropylidene-α,D-glucofuranose and intermediates for preparing these derivatives |
| CA2091587A1 (en) * | 1990-09-12 | 1992-03-13 | Greenwich Pharmaceuticals, Inc. | Monosaccharides having anti-proliferation and anti-inflammatory activity, compositions and uses thereof |
| IL100833A0 (en) * | 1991-02-20 | 1992-09-06 | Greenwich Pharma | Method for synthesis of ethereally substituted blocked monosaccharides |
-
1992
- 1992-06-29 US US07/905,320 patent/US5360792A/en not_active Expired - Fee Related
- 1992-12-16 IL IL104112A patent/IL104112A/xx not_active IP Right Cessation
- 1992-12-18 DE DE69224520T patent/DE69224520T2/de not_active Expired - Fee Related
- 1992-12-18 JP JP5511713A patent/JPH06508152A/ja active Pending
- 1992-12-18 EP EP93900164A patent/EP0581916B1/en not_active Expired - Lifetime
- 1992-12-18 NZ NZ246305A patent/NZ246305A/en unknown
- 1992-12-18 CA CA002104477A patent/CA2104477A1/en not_active Abandoned
- 1992-12-18 AT AT93900164T patent/ATE163422T1/de not_active IP Right Cessation
- 1992-12-18 WO PCT/US1992/010775 patent/WO1993013117A2/en not_active Ceased
- 1992-12-21 CN CN92115360A patent/CN1077198A/zh active Pending
-
1993
- 1993-01-29 TW TW082100540A patent/TW293013B/zh active
- 1993-08-19 FI FI933654A patent/FI106863B/fi active
Also Published As
| Publication number | Publication date |
|---|---|
| AU665977B2 (en) | 1996-01-25 |
| CN1077198A (zh) | 1993-10-13 |
| EP0581916B1 (en) | 1998-02-25 |
| TW293013B (OSRAM) | 1996-12-11 |
| NZ246305A (en) | 1996-10-28 |
| JPH06508152A (ja) | 1994-09-14 |
| AU3249593A (en) | 1993-07-28 |
| WO1993013117A2 (en) | 1993-07-08 |
| WO1993013117A3 (en) | 1993-09-30 |
| US5360792A (en) | 1994-11-01 |
| IL104112A0 (en) | 1993-05-13 |
| CA2104477A1 (en) | 1993-06-21 |
| FI933654A0 (fi) | 1993-08-19 |
| DE69224520D1 (de) | 1998-04-02 |
| EP0581916A1 (en) | 1994-02-09 |
| ATE163422T1 (de) | 1998-03-15 |
| FI933654L (fi) | 1993-08-19 |
| DE69224520T2 (de) | 1998-07-23 |
| FI106863B (fi) | 2001-04-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FF | Patent granted | ||
| KB | Patent renewed | ||
| KB | Patent renewed | ||
| RH1 | Patent not in force |