FI933654A0 - Antiproliferativa och antiinflammatoriska foereningar:5- eller 6-deoxihexosmonosackarider med en kvaeve- innehaollande maettad heterocykel i 5- eller 6-staellning, som aer bunden via kvaeveatomen - Google Patents

Antiproliferativa och antiinflammatoriska foereningar:5- eller 6-deoxihexosmonosackarider med en kvaeve- innehaollande maettad heterocykel i 5- eller 6-staellning, som aer bunden via kvaeveatomen

Info

Publication number
FI933654A0
FI933654A0 FI933654A FI933654A FI933654A0 FI 933654 A0 FI933654 A0 FI 933654A0 FI 933654 A FI933654 A FI 933654A FI 933654 A FI933654 A FI 933654A FI 933654 A0 FI933654 A0 FI 933654A0
Authority
FI
Finland
Prior art keywords
eller
maettad
kvaeveaten
kvaeve
heterocykel
Prior art date
Application number
FI933654A
Other languages
English (en)
Other versions
FI106863B (fi
FI933654A (fi
Inventor
Sudershan K Arora
David S Thomson
M Nayeem Akhtar
Original Assignee
Greenwich Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Greenwich Pharma filed Critical Greenwich Pharma
Publication of FI933654A0 publication Critical patent/FI933654A0/fi
Publication of FI933654A publication Critical patent/FI933654A/fi
Application granted granted Critical
Publication of FI106863B publication Critical patent/FI106863B/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/12—Acyclic radicals, not substituted by cyclic structures attached to a nitrogen atom of the saccharide radical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/24—Heterocyclic radicals containing oxygen or sulfur as ring hetero atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Compounds Of Unknown Constitution (AREA)
FI933654A 1991-12-20 1993-08-19 Menetelmä uusien, terapeuttisesti käyttökelpoisten 5- tai 6-deoksiheksofuranoosimonosakkaridien valmistamiseksi, joissa on 5- tai 6-asemassa tyydyttynyt typpeä sisältävä heterosykli, joka kiinnittyy typpiatomin kautta FI106863B (fi)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US81090691A 1991-12-20 1991-12-20
US81090691 1991-12-20
US07/905,320 US5360792A (en) 1991-12-20 1992-06-29 Anti-proliferative and anti-inflammatory compounds: 5- or 6-deoxy hexose monosaccharides having a saturated nitrogen-containing heterocycle at the 5- or 6-position bound through the nitrogen atom
US90532092 1992-06-29
PCT/US1992/010775 WO1993013117A2 (en) 1991-12-20 1992-12-18 5- or 6-aminodeoxyfuranoside derivatives with antiinflammatory and antiproliferative activity
US9210775 1992-12-18

Publications (3)

Publication Number Publication Date
FI933654A0 true FI933654A0 (fi) 1993-08-19
FI933654A FI933654A (fi) 1993-08-19
FI106863B FI106863B (fi) 2001-04-30

Family

ID=27123396

Family Applications (1)

Application Number Title Priority Date Filing Date
FI933654A FI106863B (fi) 1991-12-20 1993-08-19 Menetelmä uusien, terapeuttisesti käyttökelpoisten 5- tai 6-deoksiheksofuranoosimonosakkaridien valmistamiseksi, joissa on 5- tai 6-asemassa tyydyttynyt typpeä sisältävä heterosykli, joka kiinnittyy typpiatomin kautta

Country Status (12)

Country Link
US (1) US5360792A (fi)
EP (1) EP0581916B1 (fi)
JP (1) JPH06508152A (fi)
CN (1) CN1077198A (fi)
AT (1) ATE163422T1 (fi)
CA (1) CA2104477A1 (fi)
DE (1) DE69224520T2 (fi)
FI (1) FI106863B (fi)
IL (1) IL104112A (fi)
NZ (1) NZ246305A (fi)
TW (1) TW293013B (fi)
WO (1) WO1993013117A2 (fi)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5432163A (en) * 1992-11-13 1995-07-11 Greenwich Pharmaceuticals Incorporated Anti-proliferative and anti-inflammatory compounds: derivatives of pentose monosaccharides
CA2164827A1 (en) * 1993-06-11 1994-12-22 David S. Thomson Immunomodulatory, anti-inflammatory, and anti-proliferative compounds: 5,6-dideoxy, 5-amino derivatives of idose and 6-deoxy, 6-amino derivatives of glucose
US6329344B1 (en) 1998-10-22 2001-12-11 Ranbaxy Laboratories Limited Derivatives of monosaccharides as cell adhesion inhibitors
WO2000045847A1 (en) 1999-02-05 2000-08-10 Alk-Abelló A/S Novel mucosal delivery system
WO2005092907A2 (en) * 2004-03-26 2005-10-06 Ranbaxy Laboratories Limited Monosaccharide derivatives as anti-cancer and anti-inflammatory agents
WO2005100373A2 (en) * 2004-04-13 2005-10-27 Ranbaxy Laboratories Limited Monosaccharide derivatives as anti-cancer and anti-inflammatory agents
CA2571710A1 (en) * 2004-06-24 2006-11-02 Nicholas Valiante Small molecule immunopotentiators and assays for their detection
EP1789428A1 (en) * 2004-09-02 2007-05-30 Ranbaxy Laboratories Limited Monosaccharide derivatives
EP1902063A2 (en) * 2004-12-22 2008-03-26 Ranbaxy Laboratories Limited Derivatives of pentose monosaccharides as anti-inflammatory compounds
EP1842855A3 (en) * 2006-03-29 2007-12-05 Ranbaxy Laboratories Limited Monosaccharide derivatives as anti-inflammatory and/or anti-cancer agents
US7790689B2 (en) * 2006-05-30 2010-09-07 Ranbaxy Laboratories Limited Monosaccharide derivatives
EP1953170A1 (en) * 2006-10-03 2008-08-06 Ranbaxy Laboratories Limited Monosaccharide derivatives as anti-inflammatory agents

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2715121A (en) * 1950-09-09 1955-08-09 American Home Prod Alkyl sugar derivatives and their preparation
US4016261A (en) * 1973-03-01 1977-04-05 Strategic Medical Research Corporation Therapeutic composition and method of therapeutically treating warm blooded animals therewith
US3939146A (en) * 1973-03-01 1976-02-17 Strategic Medical Research Corporation Novel ethereal monosubstitutions of monosaccharide derivatives
US3965262A (en) * 1973-03-01 1976-06-22 Strategic Medical Research Corporation Method of enhancing learning and/or memory in warm blooded animals
USRE32268E (en) * 1973-03-01 1986-10-21 Strategic Medical Research Corp. Therapeutic composition and method of therapeutically treating warm blooded animals therewith
USRE30379E (en) * 1973-03-01 1980-08-19 Strategic Medical Research Corp. Ethereal monosubstitutions of monosaccharide derivatives
US3939145A (en) * 1973-03-01 1976-02-17 Strategic Medical Research Corporation Novel ethereally monosubstituted monosaccharides
US4056322A (en) * 1973-12-14 1977-11-01 Strategic Medical Research Corporation Preparation of ethers of monosaccharides
US4017608A (en) * 1973-12-14 1977-04-12 Strategic Medical Research Corporation Therapeutic composition and method of therapeutically treating warm blooded animals therewith
GB1589916A (en) * 1976-11-16 1981-05-20 Prodotti Antibiotici Spa Glucofuranose derivatives
USRE30354E (en) * 1978-02-17 1980-07-29 Strategic Medical Research Corp. Novel ethereally monosubstituted monosaccharides
USRE33000E (en) * 1981-01-12 1989-07-25 Greenwich Pharmaceuticals, Incorporated Therapeutic composition and method of treating viruses
US4738953A (en) * 1981-02-17 1988-04-19 Greenwich Pharmaceuticals Incorporated Method of therapeutically treating a warm blooded animal afflicted with an autoimmune disease and a synergistic composition therefor
US4735934A (en) * 1981-02-17 1988-04-05 Greenwich Pharmaceuticals Incorporated Method of therapeutically treating a warm blooded animal afflicted with an autoimmune disease
US4996195A (en) * 1989-01-09 1991-02-26 Greenwich Pharmaceuticals Inc. Derivatives of α,D-glucofuranose or α,D-allofuranose and intermediates for preparing these derivatives
US5010058A (en) * 1989-06-22 1991-04-23 501 Greenwich Pharmaceuticals Incorporated 3,5,6-substituted derivatives of 1,2-O-isopropylidene-α,D-glucofuranose and intermediates for preparing these derivatives
WO1992004359A2 (en) * 1990-09-12 1992-03-19 Greenwich Pharmaceuticals, Inc. Monosaccharides having anti-proliferation and anti-inflammatory activity, compositions and uses thereof
IL100833A0 (en) * 1991-02-20 1992-09-06 Greenwich Pharma Method for synthesis of ethereally substituted blocked monosaccharides

Also Published As

Publication number Publication date
AU3249593A (en) 1993-07-28
EP0581916B1 (en) 1998-02-25
IL104112A0 (en) 1993-05-13
CN1077198A (zh) 1993-10-13
FI106863B (fi) 2001-04-30
US5360792A (en) 1994-11-01
DE69224520D1 (de) 1998-04-02
EP0581916A1 (en) 1994-02-09
TW293013B (fi) 1996-12-11
ATE163422T1 (de) 1998-03-15
AU665977B2 (en) 1996-01-25
WO1993013117A3 (en) 1993-09-30
DE69224520T2 (de) 1998-07-23
WO1993013117A2 (en) 1993-07-08
JPH06508152A (ja) 1994-09-14
CA2104477A1 (en) 1993-06-21
NZ246305A (en) 1996-10-28
IL104112A (en) 1997-09-30
FI933654A (fi) 1993-08-19

Similar Documents

Publication Publication Date Title
FI933654A0 (fi) Antiproliferativa och antiinflammatoriska foereningar:5- eller 6-deoxihexosmonosackarider med en kvaeve- innehaollande maettad heterocykel i 5- eller 6-staellning, som aer bunden via kvaeveatomen
DK1105393T3 (da) Bicykliske piperidin- og piperazinforbindelser med 5-HT6-receptoraffinitet
PT1158973E (pt) Utilizacao de derivados de sulfamato para o tratamento dos disturbios do controlo de impulsos
BR9305907A (pt) Uso de derivados de substituída para tratamento de esclerose múltipla
DK0804252T3 (da) Monoamin-, diamid-, thiol-holdige metalchelateringsmidler
DK1064273T3 (da) 1,3,4-Thiadiazoler, som er nyttige til behandling af CMV-infektioner
EA200300716A1 (ru) Гетероциклилалкилиндольные или -азаиндольные соединения в качестве лиганд 5-гидрокситриптамина-6
HUP0003792A2 (hu) Vegyületek antipruriticumokként történő új alkalmazása
ES2052897T3 (es) Nucleosidos didesoxidideshidrocarbociclicos.
IL100874A0 (en) Oxypurine nucleosides and their congeners,and acyl derivatives thereof,for improvement of hematopoiesis
NO902336D0 (no) Antispasmotiske midler.
ES2091489T3 (es) Derivados de imidazol y composiciones farmaceuticas que los contienen.
JPS55111420A (en) Antitumorigenic agent
ATE113628T1 (de) Ammonium-verbindung, diese enthaltende zusammensetzung und desinfektionsverfahren.
FI923759A0 (fi) Terapeutiska bensazapinfoereningar.
NO932959L (no) Antiprolifererende og antiinflammatoriske forbindelser: 5- eller 6-deoksyheksose-monosakkarider som har en mettet nitrogenholdig heterocyklus ved 5- eller 6-stillingen, bundet ved nitrogenatomet
DE69332232D1 (de) Immunsuppressive Enpyranosederivate
IE780577L (en) Propanolamines
DK0423870T3 (da) Dibenzodioxazecin- dibenzodioxaazacycloundecinderivater
TH42831EX (th) สารปราบศัตรูพืชศัตรูสัตว์ 1-แอริล-5-(ซับสทิทิว เทด แอลคิลิดีนอิมิโน)ไพราโชล
TH13960EX (th) สารละลายโซมาโตโพรพินที่เข้ากันได้ในทางชีววิทยา
TH13372EX (th) อนุพันธ์แอโรแมทิค อะมิโน-แอลกอฮอล์ ที่มีสมบัติต่อต้านโรคเบาหวานและต่อต้านโรคอ้วนที่มีไขมันเกินปกติ, การเตรียมสารเหล่านี้และการใช้รักษาโรคของสารเหล่านี้

Legal Events

Date Code Title Description
GB Transfer or assigment of application

Owner name: BOSTON LIFE SCIENCES, INC.