IL103766A - Isolated DNA sequence comprising a gene which codes for carminomycin 4-O-methyltransferase - Google Patents

Isolated DNA sequence comprising a gene which codes for carminomycin 4-O-methyltransferase

Info

Publication number
IL103766A
IL103766A IL10376692A IL10376692A IL103766A IL 103766 A IL103766 A IL 103766A IL 10376692 A IL10376692 A IL 10376692A IL 10376692 A IL10376692 A IL 10376692A IL 103766 A IL103766 A IL 103766A
Authority
IL
Israel
Prior art keywords
carminomycin
methyltransferase
gene
codes
dna sequence
Prior art date
Application number
IL10376692A
Other languages
English (en)
Other versions
IL103766A0 (en
Inventor
Charles Richard Hutchinson
Kirshna Murthy Madduri
Francesca Torti
Anna Luisa Colombo
Original Assignee
Pharmacia & Upjohn Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US07/959,941 external-priority patent/US5364781A/en
Application filed by Pharmacia & Upjohn Spa filed Critical Pharmacia & Upjohn Spa
Publication of IL103766A0 publication Critical patent/IL103766A0/xx
Publication of IL103766A publication Critical patent/IL103766A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1003—Transferases (2.) transferring one-carbon groups (2.1)
    • C12N9/1007—Methyltransferases (general) (2.1.1.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/44—Preparation of O-glycosides, e.g. glucosides
    • C12P19/56—Preparation of O-glycosides, e.g. glucosides having an oxygen atom of the saccharide radical directly bound to a condensed ring system having three or more carbocyclic rings, e.g. daunomycin, adriamycin

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IL10376692A 1991-11-18 1992-11-17 Isolated DNA sequence comprising a gene which codes for carminomycin 4-O-methyltransferase IL103766A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US79387391A 1991-11-18 1991-11-18
US07/959,941 US5364781A (en) 1991-11-18 1992-10-09 Process for preparing daunorubicin

Publications (2)

Publication Number Publication Date
IL103766A0 IL103766A0 (en) 1993-04-04
IL103766A true IL103766A (en) 2000-12-06

Family

ID=27121440

Family Applications (1)

Application Number Title Priority Date Filing Date
IL10376692A IL103766A (en) 1991-11-18 1992-11-17 Isolated DNA sequence comprising a gene which codes for carminomycin 4-O-methyltransferase

Country Status (14)

Country Link
US (1) US5563064A (xx)
EP (1) EP0567630B1 (xx)
JP (1) JP3361522B2 (xx)
AT (1) ATE192485T1 (xx)
AU (1) AU666344B2 (xx)
CA (1) CA2100334C (xx)
DE (1) DE69230997T2 (xx)
ES (1) ES2148183T3 (xx)
FI (1) FI111012B (xx)
HU (1) HU214354B (xx)
IL (1) IL103766A (xx)
MX (1) MX9206586A (xx)
NZ (1) NZ245124A (xx)
WO (1) WO1993010223A1 (xx)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI944556A0 (fi) * 1994-09-30 1994-09-30 Kristiina Ylihonko Foerfarande foer producering av antracykliner och deras mellanprodukter
GB2302540B (en) * 1995-06-23 1999-02-24 Pharmacia Spa Cofactor for transmethylation
US5652125A (en) * 1996-06-10 1997-07-29 Pharmacia S.P.A. Process for preparing daunorubicin
US6312920B1 (en) 1996-11-13 2001-11-06 Eli Lilly And Company SAM operon
GB2330144B (en) * 1997-03-06 2001-05-02 Pharmacia & Upjohn Spa Process for preparing doxorubicin
US5976836A (en) * 1997-05-07 1999-11-02 Fermalogic, Inc. Methods and compositions for enhancing erythromycin production
CN112080454B (zh) * 2020-09-01 2022-07-08 浙江大学 一株产柔红霉素的工程链霉菌及其构建方法
CN114457101B (zh) * 2022-01-12 2024-01-12 安徽大学 通过改造糖多孢红霉菌sace_1558基因提高红霉素产量的方法及应用

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5364781A (en) * 1991-11-18 1994-11-15 Farmitalia Carlo Erba S.R.L Process for preparing daunorubicin

Also Published As

Publication number Publication date
EP0567630A1 (en) 1993-11-03
AU666344B2 (en) 1996-02-08
US5563064A (en) 1996-10-08
ATE192485T1 (de) 2000-05-15
CA2100334A1 (en) 1993-05-19
DE69230997D1 (de) 2000-06-08
MX9206586A (es) 1994-07-29
HUT69768A (en) 1995-09-28
HU214354B (hu) 1998-03-30
FI111012B (fi) 2003-05-15
JPH06505402A (ja) 1994-06-23
CA2100334C (en) 2005-05-24
WO1993010223A1 (en) 1993-05-27
FI933200A (fi) 1993-08-18
AU3129093A (en) 1993-06-15
FI933200A0 (fi) 1993-07-14
DE69230997T2 (de) 2000-08-17
IL103766A0 (en) 1993-04-04
HU9302362D0 (en) 1993-11-29
ES2148183T3 (es) 2000-10-16
NZ245124A (en) 1994-06-27
JP3361522B2 (ja) 2003-01-07
EP0567630B1 (en) 2000-05-03

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Legal Events

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